EP1578455A4 - Radioisotope-associated polymeric hydrogel microspheres and methods for producing and using the same - Google Patents
Radioisotope-associated polymeric hydrogel microspheres and methods for producing and using the sameInfo
- Publication number
- EP1578455A4 EP1578455A4 EP03779133A EP03779133A EP1578455A4 EP 1578455 A4 EP1578455 A4 EP 1578455A4 EP 03779133 A EP03779133 A EP 03779133A EP 03779133 A EP03779133 A EP 03779133A EP 1578455 A4 EP1578455 A4 EP 1578455A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- radioisotope
- producing
- methods
- same
- polymeric hydrogel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1255—Granulates, agglomerates, microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1213—Semi-solid forms, gels, hydrogels, ointments, fats and waxes that are solid at room temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Optics & Photonics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42354702P | 2002-11-04 | 2002-11-04 | |
US423547P | 2002-11-04 | ||
PCT/US2003/033140 WO2004040972A2 (en) | 2002-11-04 | 2003-10-17 | Radioisotope-associated polymeric hydrogel microspheres and methods for producing and using the same |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1578455A2 EP1578455A2 (en) | 2005-09-28 |
EP1578455A4 true EP1578455A4 (en) | 2008-12-31 |
Family
ID=32312672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03779133A Withdrawn EP1578455A4 (en) | 2002-11-04 | 2003-10-17 | Radioisotope-associated polymeric hydrogel microspheres and methods for producing and using the same |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1578455A4 (en) |
AU (1) | AU2003285905A1 (en) |
CA (1) | CA2507404A1 (en) |
WO (1) | WO2004040972A2 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7311861B2 (en) | 2004-06-01 | 2007-12-25 | Boston Scientific Scimed, Inc. | Embolization |
US20060067883A1 (en) * | 2004-09-24 | 2006-03-30 | Biosphere Medical, Inc. | Microspheres capable of binding radioisotopes, optionally comprising metallic microparticles, and methods of use thereof |
JP2008520783A (en) * | 2004-11-16 | 2008-06-19 | ユニベルシテ・ド・リエージュ | Active substance delivery system comprising a hydrogel matrix and a microcarrier |
US20090297437A1 (en) * | 2004-12-17 | 2009-12-03 | Facultes Universitaires Notre-Dame De La Paix | Radioactive device |
US7727555B2 (en) | 2005-03-02 | 2010-06-01 | Boston Scientific Scimed, Inc. | Particles |
US7963287B2 (en) | 2005-04-28 | 2011-06-21 | Boston Scientific Scimed, Inc. | Tissue-treatment methods |
US9463426B2 (en) | 2005-06-24 | 2016-10-11 | Boston Scientific Scimed, Inc. | Methods and systems for coating particles |
US20070141727A1 (en) * | 2005-12-15 | 2007-06-21 | Kimberly-Clark Worldwide, Inc. | Luminescent metallic cluster particles and uses thereof |
WO2009046281A2 (en) * | 2007-10-05 | 2009-04-09 | Boston Scientific Scimed, Inc. | Injectable particles |
WO2014159759A1 (en) | 2013-03-13 | 2014-10-02 | Biosphere Medical, Inc. | Compositions and associated methods for radioisotope-binding microparticles |
EP2923712A1 (en) | 2014-03-28 | 2015-09-30 | Spago Imaging AB | Nanostructures and applications thereof |
US10607743B2 (en) * | 2016-05-24 | 2020-03-31 | Qsa Global, Inc. | Low density spherical iridium source |
CN111012929B (en) * | 2019-11-27 | 2022-05-17 | 原子高科股份有限公司 | Suppository carrying radioactive particles and preparation method thereof |
EP4241792A1 (en) | 2022-03-08 | 2023-09-13 | Spago Nanomedical AB | Nanostructures and applications thereof |
EP4241793A1 (en) | 2022-03-08 | 2023-09-13 | Spago Nanomedical AB | Globular nanostructures |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648100A (en) * | 1991-05-29 | 1997-07-15 | Assistance Publique Hopitaux De Paris | Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same |
WO2000023054A1 (en) * | 1998-10-16 | 2000-04-27 | Biosphere Medical, S.A. | Polyvinyl alcohol microspheres, and methods for making and therapeutic uses of the same |
US6248057B1 (en) * | 1998-07-28 | 2001-06-19 | Innerdyne, Inc. | Absorbable brachytherapy and chemotherapy delivery devices and methods |
WO2002034300A1 (en) * | 2000-10-25 | 2002-05-02 | Sirtex Medical Limited | Polymer based radionuclide containing particulate material |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6015541A (en) * | 1997-11-03 | 2000-01-18 | Micro Therapeutics, Inc. | Radioactive embolizing compositions |
-
2003
- 2003-10-17 EP EP03779133A patent/EP1578455A4/en not_active Withdrawn
- 2003-10-17 WO PCT/US2003/033140 patent/WO2004040972A2/en not_active Application Discontinuation
- 2003-10-17 CA CA002507404A patent/CA2507404A1/en not_active Abandoned
- 2003-10-17 AU AU2003285905A patent/AU2003285905A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648100A (en) * | 1991-05-29 | 1997-07-15 | Assistance Publique Hopitaux De Paris | Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same |
US6248057B1 (en) * | 1998-07-28 | 2001-06-19 | Innerdyne, Inc. | Absorbable brachytherapy and chemotherapy delivery devices and methods |
WO2000023054A1 (en) * | 1998-10-16 | 2000-04-27 | Biosphere Medical, S.A. | Polyvinyl alcohol microspheres, and methods for making and therapeutic uses of the same |
WO2002034300A1 (en) * | 2000-10-25 | 2002-05-02 | Sirtex Medical Limited | Polymer based radionuclide containing particulate material |
Non-Patent Citations (4)
Title |
---|
DUCRET R P ET AL: "Therapeutic Embolization: Enhanced Radiolabeled Monitoring", RADIOLOGY, vol. 177, 1990, pages 571 - 575, XP002501359 * |
SAKAKIBARA Y ET AL: "Prevascularization with gelatin micro spheres containing basic fibroblast growth factor enhances the benefits of cardiomyocyte transplantation", JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, MOSBY-YEAR BOOK, INC., ST. LOUIS, MO, US, vol. 124, no. 1, 1 July 2002 (2002-07-01), pages 50 - 56, XP002984640, ISSN: 0022-5223 * |
VAN ES R J ET AL: "Tumour embolization of the Vx2 rabbit head and neck cancer model with Dextran hydrogel and Holmium-poly(L-lactic acid) microspheres: a radionuclide and histological pilot study", JOURNAL OF CRANIO-MAXILLO-FACIAL SURGERY : OFFICIAL PUBLICATION OF THE EUROPEAN ASSOCIATION FOR CRANIO-MAXILLO-FACIAL SURGERY OCT 2001,, vol. 29, no. 5, 1 October 2001 (2001-10-01), pages 289 - 297, XP002500322 * |
XP007906214, Retrieved from the Internet <URL:http://www.springer.com/chemistry/book/978-88-470-1103-8> [retrieved on 20081103] * |
Also Published As
Publication number | Publication date |
---|---|
WO2004040972A2 (en) | 2004-05-21 |
AU2003285905A1 (en) | 2004-06-07 |
EP1578455A2 (en) | 2005-09-28 |
WO2004040972A3 (en) | 2004-10-14 |
CA2507404A1 (en) | 2004-05-21 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20050601 |
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AX | Request for extension of the european patent |
Extension state: AL LT LV MK |
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DAX | Request for extension of the european patent (deleted) | ||
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1094764 Country of ref document: HK |
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RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: BIOSPHERE MEDICAL, INC. |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 51/12 20060101AFI20081106BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20081203 |
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STAA | Information on the status of an ep patent application or granted ep patent |
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