DK0586663T3 - Carbapenem-derivater som antibiotika samt mellemprodukter dertil - Google Patents
Carbapenem-derivater som antibiotika samt mellemprodukter dertilInfo
- Publication number
- DK0586663T3 DK0586663T3 DK93906740T DK93906740T DK0586663T3 DK 0586663 T3 DK0586663 T3 DK 0586663T3 DK 93906740 T DK93906740 T DK 93906740T DK 93906740 T DK93906740 T DK 93906740T DK 0586663 T3 DK0586663 T3 DK 0586663T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibiotics
- intermediates therefor
- carbapenem derivatives
- carbapenem
- derivatives
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- YZBQHRLRFGPBSL-RXMQYKEDSA-N carbapenem Chemical class C1C=CN2C(=O)C[C@H]21 YZBQHRLRFGPBSL-RXMQYKEDSA-N 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92400836 | 1992-03-26 | ||
| EP92402763 | 1992-10-09 | ||
| PCT/GB1993/000603 WO1993019070A1 (en) | 1992-03-26 | 1993-03-24 | Carbapenem derivatives as antibiotics and intermediates thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0586663T3 true DK0586663T3 (da) | 2000-04-10 |
Family
ID=26132349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93906740T DK0586663T3 (da) | 1992-03-26 | 1993-03-24 | Carbapenem-derivater som antibiotika samt mellemprodukter dertil |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5519015A (sk) |
| EP (1) | EP0586663B1 (sk) |
| JP (1) | JP3313366B2 (sk) |
| KR (1) | KR100283196B1 (sk) |
| CN (1) | CN1036713C (sk) |
| AP (1) | AP9300561A0 (sk) |
| AT (1) | ATE185140T1 (sk) |
| AU (1) | AU662972B2 (sk) |
| CA (1) | CA2108356C (sk) |
| CZ (1) | CZ254193A3 (sk) |
| DE (1) | DE69326588T2 (sk) |
| DK (1) | DK0586663T3 (sk) |
| ES (1) | ES2136124T3 (sk) |
| FI (1) | FI104075B (sk) |
| GB (1) | GB9304156D0 (sk) |
| GR (1) | GR3031340T3 (sk) |
| HU (1) | HUT65713A (sk) |
| IL (1) | IL105135A (sk) |
| MW (1) | MW11393A1 (sk) |
| NO (1) | NO303938B1 (sk) |
| NZ (1) | NZ249947A (sk) |
| SK (1) | SK132193A3 (sk) |
| WO (1) | WO1993019070A1 (sk) |
| ZW (1) | ZW3493A1 (sk) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9202298D0 (en) * | 1992-02-04 | 1992-03-18 | Ici Plc | Antibiotic compounds |
| CA2106330A1 (en) * | 1992-10-07 | 1994-04-08 | Patrice J. Siret | Antibiotic compounds |
| WO1994029313A1 (en) * | 1993-06-16 | 1994-12-22 | Sumitomo Pharmaceuticals Company, Limited | NOVEL β-LACTAM COMPOUND AND PROCESS FOR PRODUCING THE SAME |
| GB9515975D0 (en) | 1995-08-04 | 1995-10-04 | Zeneca Ltd | Chemical compounds |
| EP0923545A1 (en) | 1996-08-17 | 1999-06-23 | Zeneca Limited | 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors |
| JPH1077285A (ja) | 1996-09-04 | 1998-03-24 | Sumitomo Pharmaceut Co Ltd | 新規なβ−ラクタム化合物およびその製造法 |
| GB9930317D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| GB9930318D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| CN101367812B (zh) * | 2007-06-28 | 2011-04-27 | 山东轩竹医药科技有限公司 | 被巯基吡咯烷甲酰胺基环戊烯酸取代的培南衍生物 |
| CN101372490B (zh) * | 2007-08-15 | 2011-02-09 | 山东轩竹医药科技有限公司 | 含有巯基氮杂环乙烯基氮杂环的培南衍生物 |
| BRPI0905681A2 (pt) * | 2008-01-08 | 2015-07-07 | Purdue Pharma Lp | "análogos da prolina como ligantes para receptores de canabinóide" |
| CN101613352B (zh) * | 2008-06-25 | 2013-03-27 | 山东轩竹医药科技有限公司 | 含有甲酰胺杂环基巯基吡咯烷的培南衍生物 |
| IT201800009385A1 (it) | 2018-10-11 | 2020-04-11 | Isagro Spa | Derivati caffeinici ad attività nematocida, loro composizioni agronomiche e relativo uso |
| IT201900001339A1 (it) | 2019-01-30 | 2020-07-30 | Isagro Spa | Derivati teofillinici ad attività nematocida, loro composizioni agronomiche e relativo uso |
| CN113666907A (zh) * | 2021-08-25 | 2021-11-19 | 都创(上海)医药开发有限公司 | 一种基于微通道反应技术快速制备4-硝基噻吩-2-甲酸的方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0017992A1 (en) * | 1979-04-19 | 1980-10-29 | Merck & Co. Inc. | 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates |
| CA1283906C (en) * | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
| JPS60202886A (ja) * | 1984-03-27 | 1985-10-14 | Sankyo Co Ltd | １―置換カルバペネム―３―カルボン酸誘導体 |
| JPS60233076A (ja) * | 1984-05-03 | 1985-11-19 | Sumitomo Chem Co Ltd | 新規なβ−ラクタム化合物およびその製造法 |
| EP0182213B1 (en) * | 1984-11-08 | 1990-09-26 | Sumitomo Pharmaceuticals Company, Limited | Carbapenem compounds and production thereof |
| EP0243686B1 (en) * | 1986-03-27 | 1992-07-15 | Sumitomo Pharmaceuticals Company, Limited | Beta-lactam compounds, and their production |
| US4963544A (en) * | 1988-05-23 | 1990-10-16 | Fujisawa Pharmaceutical Company, Ltd. | 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds |
| US5194624A (en) * | 1988-05-23 | 1993-03-16 | Fujisawa Pharmaceutical Co., Ltd. | Intermediates for the preparation of compounds of antimicrobial activity |
| GB8923844D0 (en) * | 1989-10-23 | 1989-12-13 | Fujisawa Pharmaceutical Co | Carbapenem compounds |
| CA2036941A1 (en) * | 1990-02-23 | 1991-08-24 | Isao Kawamoto | Carbapenem derivatives having antibiotic activity, their preparation and their use |
| AU644008B2 (en) * | 1990-08-10 | 1993-12-02 | Sumitomo Pharmaceuticals Company, Limited | Beta-lactam compounds, and their production and use |
| GB9107341D0 (en) * | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| RU2093514C1 (ru) * | 1991-06-04 | 1997-10-20 | Санкио Компани Лимитед | Производные 1-метилкарбапенема и способ их получения |
-
1993
- 1993-03-02 GB GB939304156A patent/GB9304156D0/en active Pending
- 1993-03-10 ZW ZW3493A patent/ZW3493A1/xx unknown
- 1993-03-23 IL IL10513593A patent/IL105135A/xx not_active IP Right Cessation
- 1993-03-24 SK SK1321-93A patent/SK132193A3/sk unknown
- 1993-03-24 DK DK93906740T patent/DK0586663T3/da active
- 1993-03-24 DE DE69326588T patent/DE69326588T2/de not_active Expired - Lifetime
- 1993-03-24 JP JP51639893A patent/JP3313366B2/ja not_active Expired - Lifetime
- 1993-03-24 NZ NZ249947A patent/NZ249947A/en not_active IP Right Cessation
- 1993-03-24 EP EP93906740A patent/EP0586663B1/en not_active Expired - Lifetime
- 1993-03-24 AT AT93906740T patent/ATE185140T1/de active
- 1993-03-24 US US08/142,459 patent/US5519015A/en not_active Expired - Lifetime
- 1993-03-24 HU HU9303304A patent/HUT65713A/hu unknown
- 1993-03-24 CA CA002108356A patent/CA2108356C/en not_active Expired - Lifetime
- 1993-03-24 CZ CZ932541A patent/CZ254193A3/cs unknown
- 1993-03-24 AU AU37636/93A patent/AU662972B2/en not_active Expired
- 1993-03-24 KR KR1019930703616A patent/KR100283196B1/ko not_active IP Right Cessation
- 1993-03-24 ES ES93906740T patent/ES2136124T3/es not_active Expired - Lifetime
- 1993-03-24 WO PCT/GB1993/000603 patent/WO1993019070A1/en active IP Right Grant
- 1993-03-26 CN CN93102800A patent/CN1036713C/zh not_active Expired - Lifetime
- 1993-08-26 AP APAP/P/1993/000561A patent/AP9300561A0/en unknown
- 1993-10-07 MW MW11393A patent/MW11393A1/xx unknown
- 1993-11-25 FI FI935245A patent/FI104075B/fi not_active IP Right Cessation
- 1993-11-25 NO NO934264A patent/NO303938B1/no not_active IP Right Cessation
-
1999
- 1999-09-30 GR GR990402353T patent/GR3031340T3/el unknown
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