FI935245A - Antibiotikafoereningar - Google Patents

Antibiotikafoereningar Download PDF

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Publication number
FI935245A
FI935245A FI935245A FI935245A FI935245A FI 935245 A FI935245 A FI 935245A FI 935245 A FI935245 A FI 935245A FI 935245 A FI935245 A FI 935245A FI 935245 A FI935245 A FI 935245A
Authority
FI
Finland
Prior art keywords
antibiotikafoereningar
Prior art date
Application number
FI935245A
Other languages
English (en)
Other versions
FI104075B1 (fi
FI104075B (fi
FI935245A0 (fi
Inventor
Frederic Henri Jung
Original Assignee
Zeneca Ltd
Zeneca Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd, Zeneca Pharma Sa filed Critical Zeneca Ltd
Publication of FI935245A publication Critical patent/FI935245A/fi
Publication of FI935245A0 publication Critical patent/FI935245A0/fi
Application granted granted Critical
Publication of FI104075B1 publication Critical patent/FI104075B1/fi
Publication of FI104075B publication Critical patent/FI104075B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI935245A 1992-03-26 1993-11-25 Menetelmä terapeuttisesti käyttökelpoisten 2-karboksitienyylikarbamoyylipyrrolidin-4-yylitiokarbapeneemi-3-karboksyylihappojohdannaisten valmistamiseksi FI104075B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP92400836 1992-03-26
EP92400836 1992-03-26
EP92402763 1992-10-09
EP92402763 1992-10-09
GB9300603 1993-03-24
PCT/GB1993/000603 WO1993019070A1 (en) 1992-03-26 1993-03-24 Carbapenem derivatives as antibiotics and intermediates thereof

Publications (4)

Publication Number Publication Date
FI935245A true FI935245A (fi) 1993-11-25
FI935245A0 FI935245A0 (fi) 1993-11-25
FI104075B1 FI104075B1 (fi) 1999-11-15
FI104075B FI104075B (fi) 1999-11-15

Family

ID=26132349

Family Applications (1)

Application Number Title Priority Date Filing Date
FI935245A FI104075B (fi) 1992-03-26 1993-11-25 Menetelmä terapeuttisesti käyttökelpoisten 2-karboksitienyylikarbamoyylipyrrolidin-4-yylitiokarbapeneemi-3-karboksyylihappojohdannaisten valmistamiseksi

Country Status (24)

Country Link
US (1) US5519015A (fi)
EP (1) EP0586663B1 (fi)
JP (1) JP3313366B2 (fi)
KR (1) KR100283196B1 (fi)
CN (1) CN1036713C (fi)
AP (1) AP9300561A0 (fi)
AT (1) ATE185140T1 (fi)
AU (1) AU662972B2 (fi)
CA (1) CA2108356C (fi)
CZ (1) CZ254193A3 (fi)
DE (1) DE69326588T2 (fi)
DK (1) DK0586663T3 (fi)
ES (1) ES2136124T3 (fi)
FI (1) FI104075B (fi)
GB (1) GB9304156D0 (fi)
GR (1) GR3031340T3 (fi)
HU (1) HUT65713A (fi)
IL (1) IL105135A (fi)
MW (1) MW11393A1 (fi)
NO (1) NO303938B1 (fi)
NZ (1) NZ249947A (fi)
SK (1) SK132193A3 (fi)
WO (1) WO1993019070A1 (fi)
ZW (1) ZW3493A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202298D0 (en) * 1992-02-04 1992-03-18 Ici Plc Antibiotic compounds
CA2106330A1 (en) * 1992-10-07 1994-04-08 Patrice J. Siret Antibiotic compounds
WO1994029313A1 (en) * 1993-06-16 1994-12-22 Sumitomo Pharmaceuticals Company, Limited NOVEL β-LACTAM COMPOUND AND PROCESS FOR PRODUCING THE SAME
GB9515975D0 (en) 1995-08-04 1995-10-04 Zeneca Ltd Chemical compounds
EP0923545A1 (en) 1996-08-17 1999-06-23 Zeneca Limited 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors
JPH1077285A (ja) 1996-09-04 1998-03-24 Sumitomo Pharmaceut Co Ltd 新規なβ−ラクタム化合物およびその製造法
GB9930317D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds
GB9930318D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds
CN101367812B (zh) * 2007-06-28 2011-04-27 山东轩竹医药科技有限公司 被巯基吡咯烷甲酰胺基环戊烯酸取代的培南衍生物
CN101372490B (zh) * 2007-08-15 2011-02-09 山东轩竹医药科技有限公司 含有巯基氮杂环乙烯基氮杂环的培南衍生物
BRPI0905681A2 (pt) * 2008-01-08 2015-07-07 Purdue Pharma Lp "análogos da prolina como ligantes para receptores de canabinóide"
CN101613352B (zh) * 2008-06-25 2013-03-27 山东轩竹医药科技有限公司 含有甲酰胺杂环基巯基吡咯烷的培南衍生物
IT201800009385A1 (it) 2018-10-11 2020-04-11 Isagro Spa Derivati caffeinici ad attività nematocida, loro composizioni agronomiche e relativo uso
IT201900001339A1 (it) 2019-01-30 2020-07-30 Isagro Spa Derivati teofillinici ad attività nematocida, loro composizioni agronomiche e relativo uso
CN113666907A (zh) * 2021-08-25 2021-11-19 都创(上海)医药开发有限公司 一种基于微通道反应技术快速制备4-硝基噻吩-2-甲酸的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS60202886A (ja) * 1984-03-27 1985-10-14 Sankyo Co Ltd 1―置換カルバペネム―3―カルボン酸誘導体
JPS60233076A (ja) * 1984-05-03 1985-11-19 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物およびその製造法
EP0182213B1 (en) * 1984-11-08 1990-09-26 Sumitomo Pharmaceuticals Company, Limited Carbapenem compounds and production thereof
EP0243686B1 (en) * 1986-03-27 1992-07-15 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production
US4963544A (en) * 1988-05-23 1990-10-16 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
US5194624A (en) * 1988-05-23 1993-03-16 Fujisawa Pharmaceutical Co., Ltd. Intermediates for the preparation of compounds of antimicrobial activity
GB8923844D0 (en) * 1989-10-23 1989-12-13 Fujisawa Pharmaceutical Co Carbapenem compounds
CA2036941A1 (en) * 1990-02-23 1991-08-24 Isao Kawamoto Carbapenem derivatives having antibiotic activity, their preparation and their use
AU644008B2 (en) * 1990-08-10 1993-12-02 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production and use
GB9107341D0 (en) * 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
RU2093514C1 (ru) * 1991-06-04 1997-10-20 Санкио Компани Лимитед Производные 1-метилкарбапенема и способ их получения

Also Published As

Publication number Publication date
FI104075B1 (fi) 1999-11-15
IL105135A0 (en) 1993-07-08
FI104075B (fi) 1999-11-15
CA2108356A1 (en) 1993-09-27
ZW3493A1 (en) 1994-03-02
GR3031340T3 (en) 1999-12-31
HU9303304D0 (en) 1994-03-28
NZ249947A (en) 1996-02-27
HUT65713A (en) 1994-07-28
EP0586663A1 (en) 1994-03-16
MW11393A1 (en) 1994-06-08
ATE185140T1 (de) 1999-10-15
CN1036713C (zh) 1997-12-17
CA2108356C (en) 2004-01-20
SK132193A3 (en) 1994-11-09
CZ254193A3 (en) 1994-04-13
AU3763693A (en) 1993-10-21
IL105135A (en) 2000-01-31
GB9304156D0 (en) 1993-04-21
DK0586663T3 (da) 2000-04-10
JPH06508372A (ja) 1994-09-22
CN1077957A (zh) 1993-11-03
AU662972B2 (en) 1995-09-21
AP9300561A0 (en) 1995-02-26
DE69326588D1 (de) 1999-11-04
KR100283196B1 (ko) 2001-03-02
JP3313366B2 (ja) 2002-08-12
ES2136124T3 (es) 1999-11-16
FI935245A0 (fi) 1993-11-25
NO934264L (no) 1993-11-25
WO1993019070A1 (en) 1993-09-30
US5519015A (en) 1996-05-21
NO934264D0 (no) 1993-11-25
DE69326588T2 (de) 2000-01-20
EP0586663B1 (en) 1999-09-29
NO303938B1 (no) 1998-09-28

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