DK0547422T3 - Stabile pulverformige vitamin- og/eller carotenoid-præparater og fremgangsmåde til deres fremstilling - Google Patents

Stabile pulverformige vitamin- og/eller carotenoid-præparater og fremgangsmåde til deres fremstilling

Info

Publication number
DK0547422T3
DK0547422T3 DK92120456.6T DK92120456T DK0547422T3 DK 0547422 T3 DK0547422 T3 DK 0547422T3 DK 92120456 T DK92120456 T DK 92120456T DK 0547422 T3 DK0547422 T3 DK 0547422T3
Authority
DK
Denmark
Prior art keywords
preparation
methods
carotenoid preparations
stable powdery
powdery vitamin
Prior art date
Application number
DK92120456.6T
Other languages
English (en)
Inventor
Joachim U Dr Schneider
Udo Dr Rheude
Wolfgang Dr Bewert
Horst Dr Schumacher
Guenter Dr Gaus
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK0547422T3 publication Critical patent/DK0547422T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
DK92120456.6T 1991-12-14 1992-12-01 Stabile pulverformige vitamin- og/eller carotenoid-præparater og fremgangsmåde til deres fremstilling DK0547422T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4141351A DE4141351A1 (de) 1991-12-14 1991-12-14 Stabile pulverfoermige vitamin- und/oder carotinoid-praeparate und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
DK0547422T3 true DK0547422T3 (da) 1996-04-01

Family

ID=6447112

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92120456.6T DK0547422T3 (da) 1991-12-14 1992-12-01 Stabile pulverformige vitamin- og/eller carotenoid-præparater og fremgangsmåde til deres fremstilling

Country Status (7)

Country Link
US (1) US5356636A (da)
EP (1) EP0547422B1 (da)
JP (1) JP2519008B2 (da)
CA (1) CA2083754C (da)
DE (2) DE4141351A1 (da)
DK (1) DK0547422T3 (da)
IL (1) IL103866A (da)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL110139A0 (en) * 1993-06-28 1994-10-07 Howard Foundation Pharmaceutically-active antioxidants
CN1067548C (zh) * 1994-01-21 2001-06-27 上海第六制药厂 β－胡萝卜素或类胡萝卜素微型胶囊的制备及其应用
DE4405545A1 (de) * 1994-02-22 1995-08-31 Dietl Hans Fettlösliche Vitamine enthaltende Zubereitung zur oralen Applikation
DE19539574A1 (de) * 1995-10-25 1997-04-30 Boehringer Mannheim Gmbh Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren
JPH09124470A (ja) 1995-10-26 1997-05-13 Suntory Ltd 抗ストレス組成物
CA2188983C (en) 1995-10-31 2001-02-27 Kevin M. Garnett Pure 3r-3'r stereoisomer of zeaxanthin for treating macular degeneration in humans
US5854015A (en) * 1995-10-31 1998-12-29 Applied Food Biotechnology, Inc. Method of making pure 3R-3'R stereoisomer of zeaxanthin for human ingestion
US5827652A (en) * 1995-10-31 1998-10-27 Applied Food Biotechnology, Inc. Zeaxanthin formulations for human ingestion
US5747544A (en) * 1995-10-31 1998-05-05 Applied Food Biotechnology, Inc. Method of using pure 3R-3'R stereoisomer of zeaxanthin to treat or prevent retinal degeneration in humans
US5948443A (en) * 1996-02-23 1999-09-07 Medical Doctor's Research Institute, Inc. Acetylsalicylic acid and micronutrient supplementation for nutritional losses and coronary heart disease
JP3555640B2 (ja) * 1996-05-10 2004-08-18 ライオン株式会社 天然カロチノイドを包含した多芯型構造のマイクロカプセル並びに錠剤、食品用及び医薬品用配合剤
GB9616910D0 (en) * 1996-08-12 1996-09-25 Dunnett Mark A method of increasing ›-alanylihistidine pipetide synthesis and accumulation in humans and animals
DE19637517A1 (de) * 1996-09-13 1998-03-19 Basf Ag Herstellung von pulverförmigen, kaltwasserdispergierbaren Carotinoid-Zubereitungen und die Verwendung der neuen Carotinoid-Zubereitungen
DE19642359A1 (de) * 1996-10-14 1998-04-16 Basf Ag Stabile Emulsionen und Trockenpulver von Mischungen fettlöslicher Vitamine, deren Herstellung und Verwendung
DE19649062A1 (de) * 1996-11-27 1998-05-28 Basf Ag Flüssige, mit Öl mischbare Carotinoid-Zubereitungen
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
DE19703469C2 (de) * 1997-01-31 2003-10-30 Wolfgang Von Rhein Verfahren zur Herstellung eines oxidationsgeschützten Vitamin-C-Präparats
US5976568A (en) * 1997-02-21 1999-11-02 Medical Doctors' Research Institute, Inc. Modular system of dietary supplement compositions for optimizing health benefits and methods
US6007856A (en) * 1997-08-08 1999-12-28 The Procter & Gamble Company Oil-in-water dispersions of β-carotene and other carotenoids stable against oxidation prepared from water-dispersible beadlets having high concentrations of carotenoid
ID23915A (id) * 1997-10-20 2000-05-25 Dainippon Pharmaceutical Co Komposisi farmasi yang larut dengan cepat
EP0913177A1 (de) 1997-11-03 1999-05-06 Roche Diagnostics GmbH Verfahren zur Herstellung trockener, amorpher Produkte enthaltend biologisch aktive Materialien mittels Konvektionstrocknung, insbesondere Sprühtrocknung
JP4027535B2 (ja) * 1998-05-26 2007-12-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 脂溶性薬物を含有した粉末
US6146671A (en) * 1999-05-08 2000-11-14 Kemin Industries, Inc. Method and protecting heat-or oxygen-labile compounds to preserve activity and bioavailability
AU758534B2 (en) * 1998-09-25 2003-03-27 Kemin Industries, Inc. Method of protecting heat- or oxygen-labile compounds to preserve activity and bioavailability
DK1066761T3 (da) * 1999-07-06 2005-01-03 Dsm Ip Assets Bv Præparater indeholdende fedtoplöselige stoffer i en carbohydratmatrix
US6582721B1 (en) 1999-09-17 2003-06-24 Alcon, Inc. Stable carotene-xanthophyll beadlet compositions and methods of use
US6328995B1 (en) * 1999-09-24 2001-12-11 Basf Aktiengesellschaft Stable vitamin and/or carotenoid products in powder form and process for their production
JP2002051732A (ja) 2000-06-12 2002-02-19 Access Business Group Llc 食事による植物性化学物質欠乏症を矯正する組成物及び方法
US7939115B2 (en) * 2000-06-12 2011-05-10 Access Business Group International Llc Dietary supplement and related method
US7416749B2 (en) * 2000-06-12 2008-08-26 Access Business Group International Llc Dietary supplement and related method
US6989161B2 (en) 2000-06-12 2006-01-24 Access Business Group International Llc Phytonutrient nutritional supplement
US7438936B2 (en) * 2000-06-12 2008-10-21 Access Business Group International Llc Dietary supplement and related method
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US7691406B2 (en) * 2000-10-27 2010-04-06 ZeaVision LLC. Zeaxanthin formulations for human ingestion
DE10064387A1 (de) 2000-12-21 2002-06-27 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Sauerstoff-haltiger Carotinoide
US7595378B2 (en) 2001-06-13 2009-09-29 Genmab A/S Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
ATE291856T1 (de) * 2001-08-23 2005-04-15 Dsm Ip Assets Bv Neuartige, stabilisierte carotenoid-mischungen
US6663900B2 (en) * 2002-02-01 2003-12-16 Kemin Foods, Lc Microcapsules having high carotenoid content
US6974592B2 (en) * 2002-04-11 2005-12-13 Ocean Nutrition Canada Limited Encapsulated agglomeration of microcapsules and method for the preparation thereof
US6936279B2 (en) * 2002-06-18 2005-08-30 Zeavision Llc Microcrystalline zeaxanthin with high bioavailability in oily carrier formulations
CA2522036C (en) * 2002-07-08 2014-01-07 Mars, Incorporated Improved tasting energy bar
US7794764B2 (en) * 2002-10-15 2010-09-14 Mars Incorporated Preservation of process sensitive ingredients in an energy food product by product partitioning
AU2003301654A1 (en) * 2002-10-22 2004-05-13 Dainippon Pharmaceutical Co., Ltd. Stabilized composition
US8088363B2 (en) 2002-10-28 2012-01-03 Zeavision Llc Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin
KR101175774B1 (ko) * 2002-11-04 2012-08-21 오션 뉴트리션 캐나다 리미티드 다중 쉘을 갖는 마이크로캡슐 및 이의 제조 방법
US9192586B2 (en) 2003-03-10 2015-11-24 Zeavision Llc Zeaxanthin formulations with additional ocular-active nutrients, for protecting eye health and treating eye disorders
EP1433387A1 (en) * 2002-12-26 2004-06-30 Adisseo France S.A.S. Solid granules containing carotenoids
JP2006516396A (ja) 2003-01-31 2006-07-06 デーエスエム アイピー アセッツ ベー． ヴェー． カロテノイドを含む新規な組成物
WO2004084862A1 (en) * 2003-03-27 2004-10-07 Dsm Ip Assets B.V. Process for the production of cross-linked gelatin beadlets
ATE455471T1 (de) * 2003-04-03 2010-02-15 Dsm Ip Assets Bv Pulverförmige zusammensetzungen von fettlöslichen substanzen
US20070082066A1 (en) * 2003-05-07 2007-04-12 Gierhart Dennis L Use of zeaxanthin to reduce light hyper-sensitivity, photophobia, and medical conditions relating to light hyper-sensitivity
EP1643845B1 (en) * 2003-07-15 2011-11-02 DSM IP Assets B.V. Powderous formulations of fat-soluble active ingredients
CN1833052B (zh) * 2003-08-08 2010-10-20 昭和电工株式会社 带有黑膜的基质的生产方法和带有黑膜的基质
US7541166B2 (en) * 2003-09-19 2009-06-02 Microfluidic Systems, Inc. Sonication to selectively lyse different cell types
US7941211B2 (en) * 2003-11-17 2011-05-10 Zeavision, Llc. Preloading with macular pigment to improve photodynamic treatment of retinal vascular disorders
DE102004006106A1 (de) * 2004-02-06 2005-08-25 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Carotinolde
US20050186307A1 (en) * 2004-02-20 2005-08-25 Axelrod Glen S. Pet food with enhanced nutritional value
PL1732405T3 (pl) * 2004-03-18 2015-12-31 Dsm Ip Assets Bv Stabilne ekstruzyjnie kompozycje wielonienasyconych kwasów tłuszczowych do produktów spożywczych
ES2304154T3 (es) * 2004-07-09 2008-09-16 Mavi Sud S.R.L Composiciones que contienen gelatina-glicina y carotenoides.
US20060089411A1 (en) * 2004-08-07 2006-04-27 Gierhart Dennis L Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin
US8034450B2 (en) * 2005-01-21 2011-10-11 Ocean Nutrition Canada Limited Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
US20080139649A1 (en) * 2005-01-27 2008-06-12 Barrow Colin J Fatty Acid-Benzenediol Derivatives and Methods of Making and Using Thereof
US20080206316A1 (en) * 2005-01-27 2008-08-28 Colin Barrow Chromium-Fatty Acid Compounds and Methods of Making and Using Thereof
US20060182826A1 (en) * 2005-02-11 2006-08-17 Kalamazoo Holdings, Inc. Extracts of Asteraceae containing reduced levels of phototoxic thiophene derivatives and methods for preparing same
US8592662B2 (en) 2005-02-11 2013-11-26 Kalamazoo Holdings, Inc. Capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom
EP2494965A3 (en) * 2005-04-15 2013-01-02 The Albert Einstein College Of Medicine Of Yeshiva University Vitamin K for Prevention and Treatment of Skin Rash Secondary to Anti-EGFR Therapy
US9968120B2 (en) * 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
JP2009533490A (ja) * 2006-04-07 2009-09-17 オーシャン ニュートリッション カナダ リミテッド 低い界面張力を有する物質を含む乳濁液およびマイクロカプセル、ならびにそれらを作製および使用する方法
NZ596403A (en) * 2006-06-05 2013-02-22 Ocean Nutrition Canada Ltd Microcapsules with improved shells with wax in the outer shell
US8221809B2 (en) * 2006-06-22 2012-07-17 Martek Biosciences Corporation Encapsulated labile compound compositions and methods of making the same
EP2043685B1 (en) * 2006-07-03 2015-12-23 Genmab A/S Prevention of rash in patients undergoing anti-egfr therapy
CN101641087B (zh) 2007-01-10 2013-08-21 加拿大海洋营养食品有限公司 素食的微胶囊
DE102007015701A1 (de) * 2007-03-19 2008-09-25 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Neue pharmazeutische Zusammensetzungen für die Lipolyse und Verfahren zu deren Herstellung
EP2166874B1 (en) * 2007-06-19 2016-09-28 DSM IP Assets B.V. Microencapsulating compositions, methods of making, methods of using and products thereof
PT2164975E (pt) 2007-07-06 2012-03-08 Basf Se Processo para a produção de uma solução aquosa de glicose
US8815953B2 (en) * 2008-03-13 2014-08-26 Spectrum Pharmaceuticals, Inc. Formulations of vitamin K analogs for topical use
CN101971917A (zh) * 2010-08-14 2011-02-16 格特生物制药（天津）有限公司 一种畜禽用脂溶性维生素功能性饲料添加剂及其制备方法
EP2831183B1 (en) 2012-03-27 2018-08-22 3M Innovative Properties Company Composite particles, methods of making, and articles including the same
CN103284290B (zh) * 2013-05-24 2015-04-08 肇庆巨元生化有限公司 一种良好的类胡萝卜素的微囊化方法
CN103315370B (zh) * 2013-05-24 2015-04-08 肇庆巨元生化有限公司 一种稳定的类胡萝卜素的微囊化方法
CN112638492A (zh) * 2018-09-28 2021-04-09 陶氏环球技术有限责任公司 烷基醚胺泡沫控制化合物和加工食品的方法
EP4250961A1 (en) * 2020-11-30 2023-10-04 DSM IP Assets B.V. New formulations with reduced antioxidant content, their manufacture and use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB993138A (en) * 1961-11-22 1965-05-26 Pfizer & Co C Improvements in the preparation of vitamin-containing beadlets
DE3307095A1 (de) * 1983-03-01 1984-09-06 Degussa Ag, 6000 Frankfurt Mikrobiologisch hergestellte l-phenylalanin-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung
DE3484584D1 (de) * 1983-10-14 1991-06-20 Sumitomo Pharma Injektionen mit verzoegerter abgabe.
US4863950A (en) * 1985-03-12 1989-09-05 Morganti Pier F Medicinal formulation for promoting keratinogenesis and reducing seborrhea of the face and scalp
DE3610191A1 (de) * 1986-03-26 1987-10-01 Basf Ag Verfahren zur herstellung von feinteiligen, wasserdispergierbaren carotinoid-praeparationen
US4892889A (en) * 1986-11-18 1990-01-09 Basf Corporation Process for making a spray-dried, directly-compressible vitamin powder comprising unhydrolyzed gelatin
ATE64527T1 (de) * 1987-04-06 1991-07-15 Hoffmann La Roche Verfahren zur herstellung von vitaminpraeparaten.
US5153177A (en) * 1991-01-10 1992-10-06 Basf Corporation Process for incorporating a material in a crosslinked gelatin, and product therefrom

Also Published As

Publication number Publication date
JP2519008B2 (ja) 1996-07-31
US5356636A (en) 1994-10-18
EP0547422A2 (de) 1993-06-23
IL103866A0 (en) 1993-04-04
DE4141351A1 (de) 1993-06-17
IL103866A (en) 1996-12-05
EP0547422A3 (en) 1994-05-11
CA2083754C (en) 2001-08-14
EP0547422B1 (de) 1996-03-13
DE59205688D1 (de) 1996-04-18
JPH0665062A (ja) 1994-03-08
CA2083754A1 (en) 1993-06-15

Similar Documents

Publication Publication Date Title
DK0547422T3 (da) Stabile pulverformige vitamin- og/eller carotenoid-præparater og fremgangsmåde til deres fremstilling
DK56086D0 (da) 11beta-phenylgonaner, deres fremstilling og farmaceutiske praeparaterindeholdende dem
NO893678D0 (no) Cyklosporinholdige preparater og fremgangsmaate for deres fremstilling.
DK288184D0 (da) 13alfa-alkylgonaner, deres fremstilling og farmaceutiske praeparater indeholdende disse
DK166007C (da) Farvet naeringsmiddelpraeparat, isaer til dekorationsbrug og fremgangsmaade til fremstilling af praeparatet
NO900577D0 (no) Cyklosporinholdige preparater og fremgangsmaate for deres fremstilling.
DK408786A (da) Fremgangsmaade til fremstilling af vitaminforstadier og vitaminer
DK304090A (da) Glycerolderivater, fremgangsmaade til deres fremstilling og terapeutiske praeparater indeholdende disse
DK488385A (da) N6-bicycloadenosinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende saadanne forbindelser
DK514989D0 (da) Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler
DK261485D0 (da) Kosmetiske praeparater og fremgangsmaade til deres fremstilling
DK449989D0 (da) Quinolinderivater, deres fremstilling og laegemidler indeholdende disse derivater
DK299590D0 (da) Phospholipidderivater, fremgangsmaade til deres fremstilling og terapeutiske praeparater indeholdende disse
DK155692D0 (da) Benzofuranylimidazolderivater, fremgangsmaade til deres fremstilling og farmaceutiske praeparater indeholdende disse
DK443186D0 (da) Vitamin d derivater og fremgangsmaade til fremstilling deraf
DK347789D0 (da) Cysteinderivater, fremgangsmaade til fremstilling af dem og farmaceutiske praeparater indeholdende saadanne forbindelser
DK457386D0 (da) 4-substituerede catechol-derivater, fremgangsmaade til fremstillingderaf og farmaceutiske praeparater indeholdende saadanne derivater
DK9086A (da) Naphthalenderivater af benzonorbornen, fremgangsmaade til deres fremstilling og laegemidler og kosmetikpraeparater indeholdende saadanne forbindelser
DK352586A (da) 11-methylen-aestr-15-ener, fremgangsmaader til deres fremstilling og farmaceutiske praeparater indeholdende disse aestrener
DK180588D0 (da) Anti-tumor-virksomme praeparater og fremgangsmaade til deres fremstilling
DK276690A (da) Selenophenderivater, fremgangsmaade til deres fremstilling og terapeutiske praeparater indeholdende disse
DK19085D0 (da) Triazolylsubstituerede propanforbindelser, deres fremstilling og farmaceutiske praeparater, som indeholder dem
DK170290A (da) Fremgangsmaade til fremstilling af vandoploeseligt primycin og dets komponent samt farmaceutiske praeparater indeholdende dem
NO924563L (no) Benzokinoksaliner, fremgangsmaate for deres fremstilling og farmasoeytiske preparater inneholdende de nevnte forbindelser
DK182089A (da) Fremgangsmaade til fremstilling og pakning af levnedsmiddelprodukter og/eller praeparater og pakning til saadanne produkter og/eller praeparater