DK0538754T3 - Anvendelse af antistofholdige præparater til immunundertrykkelse - Google Patents

Anvendelse af antistofholdige præparater til immunundertrykkelse

Info

Publication number
DK0538754T3
DK0538754T3 DK92117775.4T DK92117775T DK0538754T3 DK 0538754 T3 DK0538754 T3 DK 0538754T3 DK 92117775 T DK92117775 T DK 92117775T DK 0538754 T3 DK0538754 T3 DK 0538754T3
Authority
DK
Denmark
Prior art keywords
immunosuppression
antibody
containing preparations
preparations
vcd44
Prior art date
Application number
DK92117775.4T
Other languages
Danish (da)
English (en)
Inventor
Margot Zoeller
Peter Herrlich
Helmut Ponta
Original Assignee
Boehringer Ingelheim Int
Deutsches Krebsforsch
Kernforschungsz Karlsruhe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Deutsches Krebsforsch, Kernforschungsz Karlsruhe filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of DK0538754T3 publication Critical patent/DK0538754T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2884—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Transplantation (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK92117775.4T 1991-10-23 1992-10-17 Anvendelse af antistofholdige præparater til immunundertrykkelse DK0538754T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4134982A DE4134982A1 (de) 1991-10-23 1991-10-23 Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression

Publications (1)

Publication Number Publication Date
DK0538754T3 true DK0538754T3 (da) 1998-03-30

Family

ID=6443260

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92117775.4T DK0538754T3 (da) 1991-10-23 1992-10-17 Anvendelse af antistofholdige præparater til immunundertrykkelse

Country Status (17)

Country Link
US (1) US5951982A (fr)
EP (1) EP0538754B1 (fr)
JP (1) JPH05310596A (fr)
KR (1) KR100252620B1 (fr)
AT (1) ATE162079T1 (fr)
AU (1) AU659687B2 (fr)
CA (1) CA2081150C (fr)
DE (2) DE4134982A1 (fr)
DK (1) DK0538754T3 (fr)
ES (1) ES2111031T3 (fr)
GR (1) GR3026526T3 (fr)
HU (1) HU216020B (fr)
IL (1) IL103510A0 (fr)
NO (1) NO311965B1 (fr)
NZ (1) NZ244851A (fr)
TW (1) TW273514B (fr)
ZA (1) ZA928162B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589458A (en) * 1992-11-13 1996-12-31 Thomas Jefferson University Compounds that inhibit T cell proliferation and methods for using the same
EP0703989B1 (fr) 1993-06-18 1997-11-05 Oy Biotie Therapies Compositions et methodes de diagnostic utilisant des anticorps monoclonaux contre le cd44v6
DE4326573A1 (de) * 1993-08-07 1995-02-23 Boehringer Ingelheim Int Durch Exon v5 des CD44-Gens kodierte Polypeptide als Targets für Immuntherapie und Immunszintigraphie von Tumoren
DE4431297A1 (de) * 1994-09-02 1996-03-07 Boehringer Ingelheim Int Monoklonaler Antikörper gegen CD44v6
DE19540515C1 (de) * 1995-10-31 1997-02-06 Boehringer Ingelheim Int Tumortherapie durch adoptiven Transfer CD44v-spezifischer zytotoxischer T-Lymphozyten
US6440733B1 (en) * 1996-02-15 2002-08-27 Chugai Seiyaku Kabushiki Kaisha Monoclonal antibodies recognizing antigens on the surface of endothelial cells of tumor vessel
US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
DE19652815C2 (de) * 1996-12-18 1999-11-11 Karlsruhe Forschzent Mittel zur Identifizierung und Therapie metastasierender Tumore
DE19653607A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Int Verfahren zur Diagnose und Therapie von Hodgkin-Lymphomen
DE19708713C2 (de) * 1997-03-04 2002-11-28 Boehringer Ingelheim Int Verwendung von anti-CD44 Antikörpern enthaltenden Präparationen zur Behandlung bestimmter Tumore und zur Unterdrückung von Immunreaktionen
IL121656A0 (en) * 1997-08-29 1998-02-08 Yissum Res Dev Co Diagnosis prevention and treatment of diabetes
US7534605B2 (en) * 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
AU2003272511A1 (en) * 2002-09-13 2004-04-30 Dyax Corporation Cd44-binding ligands
US9701754B1 (en) 2002-10-23 2017-07-11 City Of Hope Covalent disulfide-linked diabodies and uses thereof
US20070280930A1 (en) * 2004-03-17 2007-12-06 Kasper Mathias Antoon Rouschop Cd44-Targeting for Reducing/Preventing Ischemia-Reperfusion-Injury
WO2007025166A2 (fr) 2005-08-25 2007-03-01 Repair Technologies, Inc. Dispositifs, compositions et methodes de protection et de reparation de cellules et de tissus
ATE509033T1 (de) 2006-03-20 2011-05-15 Univ California Manipulierte anti-prostatastammzellenantigen (psca)-antikörper für krebs-targeting
CA2698343C (fr) 2007-09-04 2018-06-12 The Regents Of The University Of California Anticorps d'antigene de cellule souche anti-prostate (psca) a haute affinite pour un ciblage et une detection de cancer
WO2010058396A1 (fr) 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Anticorps anti-cd44vra et procédés diagnostiques et thérapeutiques l'utilisant
ES2712732T3 (es) 2009-02-17 2019-05-14 Cornell Res Foundation Inc Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
EP3511023A1 (fr) 2009-12-02 2019-07-17 Imaginab, Inc. Minicorps j591 et cys-diacorps pour cibler l'antigène membranaire spécifique de la prostate humaine (psma) et leurs procédés d'utilisation
DK2886126T3 (en) 2013-12-23 2017-09-18 Exchange Imaging Tech Gmbh Nanoparticle conjugated to CD44-binding peptides
BR112017000710B1 (pt) 2014-07-15 2024-02-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Polipeptídeo isolado, composição de matéria, e, uso do polipeptídeo isolado ou da composição da matéria
EP3331564A4 (fr) 2015-08-07 2019-05-22 Imaginab, Inc. Constructions de liaison d'antigène se liant à des molécules cibles
WO2018147960A1 (fr) 2017-02-08 2018-08-16 Imaginab, Inc. Séquences d'extension pour dianticorps
US11313243B2 (en) 2018-07-12 2022-04-26 Rolls-Royce North American Technologies, Inc. Non-continuous abradable coatings

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0303463B1 (fr) * 1987-08-11 1994-11-30 The Board Of Trustees Of The Leland Stanford Junior University Méthode pour contrôler l'extravasation des leucocytes
DE4014510A1 (de) * 1990-05-07 1991-11-14 Kernforschungsz Karlsruhe Variante cd44-oberflaechenproteine, diese kodierende c-dna-sequenzen, antikoerper gegen diese proteine sowie ihre verwendung in der diagnostik und therapie
CA2059824A1 (fr) * 1991-02-26 1992-08-27 Thomas M. Aune Hybridomes et anticorps monoclonaux qui inhibent la proliferation des lymphocytes t stimules anti-cd3
EP0703989B1 (fr) * 1993-06-18 1997-11-05 Oy Biotie Therapies Compositions et methodes de diagnostic utilisant des anticorps monoclonaux contre le cd44v6

Also Published As

Publication number Publication date
EP0538754B1 (fr) 1998-01-14
GR3026526T3 (en) 1998-07-31
NO311965B1 (no) 2002-02-25
NZ244851A (en) 1997-07-27
IL103510A0 (en) 1993-03-15
ES2111031T3 (es) 1998-03-01
NO924103L (no) 1993-04-26
ZA928162B (en) 1993-05-05
EP0538754A2 (fr) 1993-04-28
DE59209129D1 (de) 1998-02-19
NO924103D0 (no) 1992-10-22
CA2081150A1 (fr) 1993-04-24
KR100252620B1 (ko) 2000-09-01
CA2081150C (fr) 2001-04-10
ATE162079T1 (de) 1998-01-15
JPH05310596A (ja) 1993-11-22
AU2724492A (en) 1993-04-29
KR930007460A (ko) 1993-05-20
US5951982A (en) 1999-09-14
AU659687B2 (en) 1995-05-25
HUT63063A (en) 1993-07-28
TW273514B (fr) 1996-04-01
DE4134982A1 (de) 1993-04-29
HU216020B (hu) 1999-04-28
EP0538754A3 (en) 1994-05-25

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