DK0535231T3 - Pyrimidinnucleosid-derivater - Google Patents

Pyrimidinnucleosid-derivater

Info

Publication number
DK0535231T3
DK0535231T3 DK91911192.2T DK91911192T DK0535231T3 DK 0535231 T3 DK0535231 T3 DK 0535231T3 DK 91911192 T DK91911192 T DK 91911192T DK 0535231 T3 DK0535231 T3 DK 0535231T3
Authority
DK
Denmark
Prior art keywords
pyrimidine nucleoside
nucleoside derivatives
hydroxy
hydrogen
represent
Prior art date
Application number
DK91911192.2T
Other languages
Danish (da)
English (en)
Inventor
Tohru Ueda
Akira Matsuda
Takuma Sasaki
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of DK0535231T3 publication Critical patent/DK0535231T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK91911192.2T 1990-06-15 1991-06-13 Pyrimidinnucleosid-derivater DK0535231T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15668890 1990-06-15

Publications (1)

Publication Number Publication Date
DK0535231T3 true DK0535231T3 (da) 1995-08-21

Family

ID=15633157

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91911192.2T DK0535231T3 (da) 1990-06-15 1991-06-13 Pyrimidinnucleosid-derivater

Country Status (13)

Country Link
US (2) US5616567A (de)
EP (1) EP0535231B1 (de)
JP (1) JP2559917B2 (de)
KR (1) KR970011306B1 (de)
AT (1) ATE122041T1 (de)
CA (1) CA2085345C (de)
DE (1) DE69109482T2 (de)
DK (1) DK0535231T3 (de)
ES (1) ES2074719T3 (de)
HK (1) HK1005871A1 (de)
HU (1) HU218924B (de)
RU (1) RU2116306C1 (de)
WO (1) WO1991019713A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2085557C1 (ru) * 1991-09-30 1997-07-27 Санкио Компани Лимитед Производные нуклеозидов пиримидина или их фармацевтически приемлемые соли и способ их получения
EP1736478B1 (de) * 2000-05-26 2015-07-22 IDENIX Pharmaceuticals, Inc. Verfahren und Zusammensetzungen zur Behandlung von Flaviviren und Pestiviren
TW200637870A (en) * 2005-01-31 2006-11-01 Taiho Pharmaceutical Co Ltd Novel pyrimidine nucleoside compound and salt thereof
GB0523041D0 (en) * 2005-11-11 2005-12-21 Cyclacel Ltd Combination
WO2008010571A1 (fr) 2006-07-21 2008-01-24 Taiho Pharmaceutical Co., Ltd. Composé nucléosidique de 2'cyanopyrimidine
GB0625283D0 (en) 2006-12-19 2007-01-24 Cyclacel Ltd Combination
MX2010003261A (es) * 2007-09-26 2010-08-18 Sinai School Medicine Analogos de azacitidina y usos de los mismos.
US8124593B2 (en) 2007-11-05 2012-02-28 Cyclacel Limited Methods of treatment using sapacitabine
US7863255B2 (en) * 2008-04-29 2011-01-04 Taiho Pharmaceutical Co., Ltd. Methods of administering antitumor agent comprising deoxycytidine derivative
GB0808359D0 (en) * 2008-05-08 2008-06-18 Cyclacel Ltd Process
GB0808357D0 (en) * 2008-05-08 2008-06-18 Cyclacel Ltd Process
EP2307002B1 (de) 2008-06-09 2013-01-02 Cyclacel Limited Kombinationen von sapacitabin oder cndac mit dna-methyltransferase-inhibitoren wie decitabin und procain
PT2431376E (pt) 2009-05-15 2013-09-17 Delta Fly Pharma Inc Novo cristal estável de monocloridrato de 1-(2¿-ciano-2¿- desoxi-β-d-arabinofuranosil)citosina
EP3560501A1 (de) 2011-04-14 2019-10-30 Cyclacel Limited Dosierungsschema für sapacitabin und decitabin in kombination zur behandlung von akuter myeloischer leukämie
EP2794627B1 (de) 2011-12-22 2018-09-26 Alios Biopharma, Inc. Substituierte nukleoside, nukleotide und analoga davon
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
EP2874631A1 (de) 2012-05-15 2015-05-27 Cyclacel Limited Dosierungsschema für sapacitabin und seliciclib
WO2019081951A1 (en) 2017-10-27 2019-05-02 Cyclacel Limited DOSAGE REGIME
US11957701B2 (en) 2020-07-17 2024-04-16 Delta-Fly Pharma, Inc. Therapy and new therapeutic agent for blood cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2007094A6 (es) * 1987-07-29 1989-06-01 Consejo Superior Investigacion Procedimiento para la preparacion de 3 -c- ciano-2,3 -didesoxinucleosido.

Also Published As

Publication number Publication date
KR970011306B1 (ko) 1997-07-09
EP0535231B1 (de) 1995-05-03
CA2085345A1 (en) 1991-12-16
CA2085345C (en) 2001-08-07
HU218924B (hu) 2000-12-28
WO1991019713A1 (en) 1991-12-26
US5616567A (en) 1997-04-01
JPH04235182A (ja) 1992-08-24
RU2116306C1 (ru) 1998-07-27
HK1005871A1 (en) 1999-01-29
EP0535231A4 (en) 1993-06-30
HU9203967D0 (en) 1993-03-29
EP0535231A1 (de) 1993-04-07
HUT62582A (en) 1993-05-28
JP2559917B2 (ja) 1996-12-04
ES2074719T3 (es) 1995-09-16
KR930700485A (ko) 1993-03-15
US5654420A (en) 1997-08-05
ATE122041T1 (de) 1995-05-15
DE69109482T2 (de) 1996-02-15
DE69109482D1 (en) 1995-06-08

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