DK0533840T3 - Behandling af kronisk nyresvigt med imidazol-angiotensin-II-receptor-antagonister - Google Patents

Behandling af kronisk nyresvigt med imidazol-angiotensin-II-receptor-antagonister

Info

Publication number
DK0533840T3
DK0533840T3 DK91912884.3T DK91912884T DK0533840T3 DK 0533840 T3 DK0533840 T3 DK 0533840T3 DK 91912884 T DK91912884 T DK 91912884T DK 0533840 T3 DK0533840 T3 DK 0533840T3
Authority
DK
Denmark
Prior art keywords
imidazole
angiotensin
renal failure
chronic renal
treatment
Prior art date
Application number
DK91912884.3T
Other languages
English (en)
Inventor
David John Carini
John Jonas Vytautas Duncia
Pancras Chor-Bun Wong
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of DK0533840T3 publication Critical patent/DK0533840T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK91912884.3T 1990-06-22 1991-06-07 Behandling af kronisk nyresvigt med imidazol-angiotensin-II-receptor-antagonister DK0533840T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54235190A 1990-06-22 1990-06-22

Publications (1)

Publication Number Publication Date
DK0533840T3 true DK0533840T3 (da) 1996-12-30

Family

ID=24163446

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91912884.3T DK0533840T3 (da) 1990-06-22 1991-06-07 Behandling af kronisk nyresvigt med imidazol-angiotensin-II-receptor-antagonister

Country Status (8)

Country Link
EP (1) EP0533840B1 (da)
JP (2) JPH05509086A (da)
AT (1) ATE146076T1 (da)
CA (1) CA2085584C (da)
DE (1) DE69123582T2 (da)
DK (1) DK0533840T3 (da)
GR (1) GR3022035T3 (da)
WO (1) WO1992000067A2 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2058198A1 (en) * 1991-01-04 1992-07-05 Adalbert Wagner Azole derivatives, process for their preparation, and their use
JP3810020B2 (ja) 1993-04-22 2006-08-16 武田薬品工業株式会社 腎疾患の予防または治療剤
FR2719598B1 (fr) * 1994-05-03 1996-07-26 Rhone Poulenc Chimie Composition élastomère silicone et ses applications, notamment pour l'enduction de sac gonflable, destiné à la protection d'un occupant de véhicule.
AU677702B2 (en) * 1994-10-13 1997-05-01 Takeda Pharmaceutical Company Limited A prophylactic or therapeutic drug for renal diseases
US6498142B1 (en) 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
ATE278414T1 (de) 1997-05-05 2004-10-15 Curis Inc Therapien zur behandlung von akutem nierenversagen
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
KR100637564B1 (ko) 2001-01-26 2006-10-20 추가이 세이야쿠 가부시키가이샤 대사 조절자로서 유용한 말로닐-코에이 데카르복실라제억제제
ES2284817T3 (es) 2001-01-26 2007-11-16 Chugai Seiyaku Kabushiki Kaisha Procedimientos para el tratamiento de enfermedades con inhibidores de la malonil coa descarboxilasa.
WO2002064136A2 (en) 2001-01-26 2002-08-22 Chugai Seiyaku Kabushiki Kaisha Malonyl-coa decarboxylase inhibitors useful as metabolic modulators
US7709510B2 (en) 2001-02-20 2010-05-04 Chugai Seiyaku Kabushiki Kaisha Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
PL204456B1 (pl) 2001-02-20 2010-01-29 Chugai Pharmaceutical Co Ltd Związki azolowe, ich zastosowanie i środek farmaceutyczny
ES2295930T3 (es) 2003-08-01 2008-04-16 Chugai Seiyaku Kabushiki Kaisha Compuestos de cianoamida utiles como inhibidores de malonil-coa descarboxilasa.
ES2314491T3 (es) 2003-08-01 2009-03-16 Chugai Seiyaku Kabushiki Kaisha Compuestos azol basados en cianoguanidina utiles como inhibidores de la manonil-coa descaraboxilasa.
US7696365B2 (en) 2003-08-01 2010-04-13 Chugai Seiyaku Kabushiki Kaisha Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors
DE602004014937D1 (de) 2003-08-01 2008-08-21 Chugai Pharmaceutical Co Ltd Piperidin-verbindungen als malonyl-coa decarboxylase-hemmer
US8257797B2 (en) 2003-11-03 2012-09-04 Bluestar Silicones France Silicone composition and process that is useful for improving the tear strength and the combing strength of an inflatable bag for protecting an occupant of a vehicle
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX2009013293A (es) 2007-06-04 2010-02-15 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos.
EP2297113A1 (en) * 2008-04-29 2011-03-23 Theravance, Inc. Dual-acting antihypertensive agents
ES2627848T3 (es) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
WO2011077712A1 (ja) * 2009-12-22 2011-06-30 興和株式会社 新規な１－（ビフェニル－４－イル－メチル）－１ｈ－イミダゾール誘導体及びこれを含有する医薬
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
KR102272746B1 (ko) 2013-06-05 2021-07-08 보슈 헬스 아일랜드 리미티드 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법
US11407733B2 (en) 2016-06-29 2022-08-09 Bristol-Myers Squibb Company Biarylmethyl heterocycles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
ATE190051T1 (de) * 1989-06-14 2000-03-15 Smithkline Beecham Corp Imidazoalkensäure
KR0163595B1 (ko) * 1989-06-30 1998-12-01 미리암디, 메코너헤이 치환된 이미다졸
CA2032289A1 (en) * 1989-12-29 1991-06-30 Joseph A. Finkelstein Substituted 5-(alkyl) carboxamide imidazoles

Also Published As

Publication number Publication date
CA2085584A1 (en) 1991-12-23
GR3022035T3 (en) 1997-03-31
DE69123582D1 (de) 1997-01-23
EP0533840B1 (en) 1996-12-11
JPH11228410A (ja) 1999-08-24
EP0533840A1 (en) 1993-03-31
ATE146076T1 (de) 1996-12-15
JPH05509086A (ja) 1993-12-16
WO1992000067A3 (en) 1993-05-27
WO1992000067A2 (en) 1992-01-09
DE69123582T2 (de) 1997-05-15
CA2085584C (en) 2003-02-11

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