ATE371645T1 - Naphthalinderivate, die sich an den ep4?rezeptor binden - Google Patents
Naphthalinderivate, die sich an den ep4?rezeptor bindenInfo
- Publication number
- ATE371645T1 ATE371645T1 AT01271355T AT01271355T ATE371645T1 AT E371645 T1 ATE371645 T1 AT E371645T1 AT 01271355 T AT01271355 T AT 01271355T AT 01271355 T AT01271355 T AT 01271355T AT E371645 T1 ATE371645 T1 AT E371645T1
- Authority
- AT
- Austria
- Prior art keywords
- bind
- receptor
- naphthaline derivatives
- derivatives
- naphthaline
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
- C07D209/64—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with an oxygen atom in position 1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
- C07D209/66—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with oxygen atoms in positions 1 and 3
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
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- Diabetes (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Addiction (AREA)
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- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0031302.3A GB0031302D0 (en) | 2000-12-21 | 2000-12-21 | Napthalene derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE371645T1 true ATE371645T1 (de) | 2007-09-15 |
Family
ID=9905630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01271355T ATE371645T1 (de) | 2000-12-21 | 2001-12-20 | Naphthalinderivate, die sich an den ep4?rezeptor binden |
Country Status (9)
Country | Link |
---|---|
US (1) | US6924297B2 (de) |
EP (1) | EP1351934B1 (de) |
JP (1) | JP4397586B2 (de) |
AT (1) | ATE371645T1 (de) |
AU (1) | AU2002216218A1 (de) |
DE (1) | DE60130256T2 (de) |
ES (1) | ES2290093T3 (de) |
GB (1) | GB0031302D0 (de) |
WO (1) | WO2002050032A1 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HN2001000224A (es) | 2000-10-19 | 2002-06-13 | Pfizer | Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos. |
GB0031295D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Naphthalene derivatives |
US20090036495A1 (en) * | 2004-04-20 | 2009-02-05 | Pfizer, Inc. | Combinations Comprising Alpha-2-Delta Ligands and Ep4 Receptor Antagonists |
US8013159B2 (en) | 2005-05-19 | 2011-09-06 | Merck Canada Inc. | Quinoline derivatives as EP4 antagonists |
UY30121A1 (es) | 2006-02-03 | 2007-08-31 | Glaxo Group Ltd | Nuevos compuestos |
GB0615111D0 (en) * | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
GB0615105D0 (en) * | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
CA2672631A1 (en) | 2006-12-15 | 2008-06-19 | Glaxo Group Limited | Benzamide derivatives as ep4 receptor agonists |
US8003661B2 (en) | 2007-03-26 | 2011-08-23 | Merck Canada Inc. | Naphthalene and quinoline sulfonylurea derivatives as EP4 receptor antagonists |
GB0721611D0 (en) | 2007-11-02 | 2007-12-12 | Glaxo Group Ltd | Novel compounds |
EP2149554A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma Aktiengesellschaft | Indolylamide als Modulatoren des EP2-Rezeptors |
EP2149551A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | N-(Indol-3-ylalkyl)-(hetero)arylamidderivate als Modulatoren des EP2-Rezeptors |
EP2149552A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | 5,6 substituierte Benzamid-Derivate als Modulatoren des EP2-Rezeptors |
WO2010087425A1 (ja) | 2009-01-30 | 2010-08-05 | 国立大学法人京都大学 | 前立腺癌の進行抑制剤および進行抑制方法 |
DE102009049662A1 (de) | 2009-10-13 | 2011-04-14 | Bayer Schering Pharma Aktiengesellschaft | 2,5-Disubstituierte 2H-Indazole als EP2-Rezeptor-Antagonisten |
US20120190637A1 (en) | 2009-10-14 | 2012-07-26 | Gemmus Pharma, Inc. | Combination therapy treatment for viral infections |
MX2016001714A (es) | 2013-08-09 | 2016-10-03 | Ardelyx Inc | Compuestos y metodos para inhibir el transporte de fosfato. |
MX2017009037A (es) * | 2015-01-09 | 2017-10-04 | Ono Pharmaceutical Co | Compuestos espiro triciclicos. |
CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
JP6269888B1 (ja) * | 2016-07-07 | 2018-01-31 | 小野薬品工業株式会社 | 医薬用途 |
KR102626982B1 (ko) | 2017-05-18 | 2024-01-18 | 이도르시아 파마슈티컬스 리미티드 | Pge2 수용체 조절제로서의 피리미딘 유도체 |
AU2018269666B2 (en) | 2017-05-18 | 2022-02-03 | Idorsia Pharmaceuticals Ltd | Phenyl derivatives as PGE2 receptor modulators |
WO2018210992A1 (en) | 2017-05-18 | 2018-11-22 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives |
CN110621671A (zh) | 2017-05-18 | 2019-12-27 | 爱杜西亚药品有限公司 | 作为pge2受体调节剂的苯并呋喃及苯并噻吩衍生物 |
PT3625224T (pt) | 2017-05-18 | 2021-10-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-substituídos |
EP3759102A1 (de) | 2018-03-02 | 2021-01-06 | Inflazome Limited | Neuartige verbindungen |
WO2019166632A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
WO2019166628A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
EP3759073A1 (de) * | 2018-03-02 | 2021-01-06 | Inflazome Limited | Sulfonamidderivate als nlrp3-inhibitoren |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4014899A (en) * | 1973-10-29 | 1977-03-29 | Ciba-Geigy Corporation | 5,6-Benzoisoindolines |
US4395417A (en) * | 1980-04-22 | 1983-07-26 | Research Corporation | Antihyperlipidemic compositions |
ID18046A (id) * | 1996-08-20 | 1998-02-19 | Takeda Chemical Industries Ltd | Senyawa siklik campuran, pembuatan dan penngunaannya. |
DE19650975A1 (de) | 1996-12-09 | 1998-06-10 | Basf Ag | Neue heterocyclisch substituierte Benzamide und deren Anwendung |
JP2003502313A (ja) * | 1999-06-10 | 2003-01-21 | ワーナー−ランバート・カンパニー | イソインドリン誘導体を用いたアミロイドタンパク質凝集抑制およびアミロイド付着部画像化の方法 |
-
2000
- 2000-12-21 GB GBGB0031302.3A patent/GB0031302D0/en not_active Ceased
-
2001
- 2001-12-20 JP JP2002551529A patent/JP4397586B2/ja not_active Expired - Fee Related
- 2001-12-20 EP EP01271355A patent/EP1351934B1/de not_active Expired - Lifetime
- 2001-12-20 WO PCT/GB2001/005676 patent/WO2002050032A1/en active IP Right Grant
- 2001-12-20 US US10/450,891 patent/US6924297B2/en not_active Expired - Fee Related
- 2001-12-20 AT AT01271355T patent/ATE371645T1/de not_active IP Right Cessation
- 2001-12-20 DE DE60130256T patent/DE60130256T2/de not_active Expired - Lifetime
- 2001-12-20 AU AU2002216218A patent/AU2002216218A1/en not_active Abandoned
- 2001-12-20 ES ES01271355T patent/ES2290093T3/es not_active Expired - Lifetime
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EP1351934A1 (de) | 2003-10-15 |
DE60130256D1 (de) | 2007-10-11 |
GB0031302D0 (en) | 2001-01-31 |
JP2004517099A (ja) | 2004-06-10 |
ES2290093T3 (es) | 2008-02-16 |
JP4397586B2 (ja) | 2010-01-13 |
WO2002050032A1 (en) | 2002-06-27 |
DE60130256T2 (de) | 2008-05-21 |
AU2002216218A1 (en) | 2002-07-01 |
US20040102508A1 (en) | 2004-05-27 |
US6924297B2 (en) | 2005-08-02 |
EP1351934B1 (de) | 2007-08-29 |
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