ATE533766T1 - Chinolinderivate als ep4-antagonisten - Google Patents

Chinolinderivate als ep4-antagonisten

Info

Publication number
ATE533766T1
ATE533766T1 AT06741503T AT06741503T ATE533766T1 AT E533766 T1 ATE533766 T1 AT E533766T1 AT 06741503 T AT06741503 T AT 06741503T AT 06741503 T AT06741503 T AT 06741503T AT E533766 T1 ATE533766 T1 AT E533766T1
Authority
AT
Austria
Prior art keywords
derivatives
group
quinoline derivatives
antagonists
formula
Prior art date
Application number
AT06741503T
Other languages
English (en)
Inventor
Michel Belley
Jason Burch
John Colucci
Julie Farand
Mario Girard
Yongxin Han
Original Assignee
Merck Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Canada Inc filed Critical Merck Canada Inc
Application granted granted Critical
Publication of ATE533766T1 publication Critical patent/ATE533766T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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AT06741503T 2005-05-19 2006-05-15 Chinolinderivate als ep4-antagonisten ATE533766T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68258905P 2005-05-19 2005-05-19
PCT/CA2006/000789 WO2006122403A1 (en) 2005-05-19 2006-05-15 Quinoline derivatives as ep4 antagonists

Publications (1)

Publication Number Publication Date
ATE533766T1 true ATE533766T1 (de) 2011-12-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
AT06741503T ATE533766T1 (de) 2005-05-19 2006-05-15 Chinolinderivate als ep4-antagonisten

Country Status (7)

Country Link
US (1) US8013159B2 (de)
EP (1) EP1885722B1 (de)
JP (1) JP5289046B2 (de)
AT (1) ATE533766T1 (de)
AU (1) AU2006246930C1 (de)
CA (1) CA2608214C (de)
WO (1) WO2006122403A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR057023A1 (es) * 2005-05-16 2007-11-14 Gilead Sciences Inc Compuestos heterociclicos con propiedades inhibidoras de hiv-integrasa
UY30121A1 (es) 2006-02-03 2007-08-31 Glaxo Group Ltd Nuevos compuestos
WO2008071736A1 (en) 2006-12-15 2008-06-19 Glaxo Group Limited Benzamide derivatives as ep4 receptor agonists
US8158671B2 (en) * 2007-02-26 2012-04-17 Merck Canada Inc. Indole and indoline cyclopropyl amide derivatives as EP4 receptor antagonists
JP2010522218A (ja) * 2007-03-26 2010-07-01 メルク フロスト カナダ リミテツド Ｅｐ４受容体アンタゴニストとしてのナフタレン及びキノリンスルホニル尿素誘導体
GB0721611D0 (en) 2007-11-02 2007-12-12 Glaxo Group Ltd Novel compounds
CN102224154A (zh) 2008-09-25 2011-10-19 默克弗罗斯特加拿大有限公司 作为EP4受体拮抗剂的β-咔啉磺酰脲衍生物
WO2010087425A1 (ja) 2009-01-30 2010-08-05 国立大学法人京都大学 前立腺癌の進行抑制剤および進行抑制方法
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