DK0527942T3 - System til frigivelse af et lægemiddel i tyktarmen - Google Patents

System til frigivelse af et lægemiddel i tyktarmen

Info

Publication number
DK0527942T3
DK0527942T3 DK91910743T DK91910743T DK0527942T3 DK 0527942 T3 DK0527942 T3 DK 0527942T3 DK 91910743 T DK91910743 T DK 91910743T DK 91910743 T DK91910743 T DK 91910743T DK 0527942 T3 DK0527942 T3 DK 0527942T3
Authority
DK
Denmark
Prior art keywords
colon
drug
matrix
stomach
degraded
Prior art date
Application number
DK91910743T
Other languages
English (en)
Inventor
Amnon Sintov
Abraham Rubinstein
Original Assignee
Yissum Res Dev Co
Perio Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24065163&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0527942(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yissum Res Dev Co, Perio Prod Ltd filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of DK0527942T3 publication Critical patent/DK0527942T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0045—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Galacturonans, e.g. methyl ester of (alpha-1,4)-linked D-galacturonic acid units, i.e. pectin, or hydrolysis product of methyl ester of alpha-1,4-linked D-galacturonic acid units, i.e. pectinic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Surgical Instruments (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Memory System Of A Hierarchy Structure (AREA)
DK91910743T 1990-05-04 1991-05-02 System til frigivelse af et lægemiddel i tyktarmen DK0527942T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51871490A 1990-05-04 1990-05-04
PCT/US1991/003014 WO1991016881A1 (en) 1990-05-04 1991-05-02 Colonic drug delivery system

Publications (1)

Publication Number Publication Date
DK0527942T3 true DK0527942T3 (da) 2000-03-27

Family

ID=24065163

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91910743T DK0527942T3 (da) 1990-05-04 1991-05-02 System til frigivelse af et lægemiddel i tyktarmen

Country Status (17)

Country Link
EP (1) EP0527942B1 (da)
JP (1) JPH05508631A (da)
KR (1) KR100194161B1 (da)
AT (1) ATE185267T1 (da)
AU (1) AU660147B2 (da)
BR (1) BR9106419A (da)
CA (1) CA2082156A1 (da)
DE (2) DE69131688T2 (da)
DK (1) DK0527942T3 (da)
ES (1) ES2048133T3 (da)
FI (1) FI924984A0 (da)
GR (2) GR940300025T1 (da)
HU (1) HU210497B (da)
MC (1) MC2288A1 (da)
NO (1) NO306096B1 (da)
RU (1) RU2113221C1 (da)
WO (1) WO1991016881A1 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4209160A1 (de) * 1992-03-20 1993-09-30 Bauer Kurt Heinz Prof Dr Vernetzte Polysaccharide, Verfahren zu ihrer Herstellung und ihre Verwendung
US5656290A (en) * 1993-02-26 1997-08-12 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
EP0730447B1 (en) * 1993-11-17 2002-02-20 Commonwealth Scientific And Industrial Research Organisation Fatty acid delivery system
AU695906B2 (en) * 1993-11-17 1998-08-27 Commonwealth Scientific And Industrial Research Organisation Fatty acid delivery system
DE4340057A1 (de) * 1993-11-24 1995-06-01 Falk Pharma Gmbh Budesonid-Arzneimittel zur Verbesserung der enteralen Flüssigkeitsresorption, insbesondere nach postoperativen Zuständen
DE69528583T2 (de) * 1994-04-22 2003-07-10 Yamanouchi Pharmaceutical Co., Ltd. Kolon-spezifisches arzneistofffreisetzungssystem
US5849327A (en) * 1994-07-29 1998-12-15 Advanced Polymer Systems, Inc. Delivery of drugs to the lower gastrointestinal tract
US5811388A (en) * 1995-06-07 1998-09-22 Cibus Pharmaceutical, Inc. Delivery of drugs to the lower GI tract
US5656294A (en) * 1995-06-07 1997-08-12 Cibus Pharmaceutical, Inc. Colonic delivery of drugs
GB9516268D0 (en) 1995-08-08 1995-10-11 Danbiosyst Uk Compositiion for enhanced uptake of polar drugs from the colon
ES2163000T3 (es) * 1996-01-16 2002-01-16 Advanced Polymer Systems Inc Suministro topico de farmacos al tracto gastrointestinal inferior.
FR2752843B1 (fr) * 1996-08-30 1998-10-16 Sod Conseils Rech Applic Copolymeres reticules a base de polymeres polycarboxyliques et leur utilisation comme support de composition pharmaceutique
WO1998026767A2 (en) * 1996-12-17 1998-06-25 Poli Industria Chimica S.P.A. Site-specific controlled release dosage formulation for mesalamine
US6229009B1 (en) 1997-08-29 2001-05-08 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Polycarboxylic based cross-linked copolymers
AU2484399A (en) 1998-01-30 1999-08-16 Scios Inc. Controlled release delivery of peptide or protein
KR20000011247A (ko) * 1998-07-23 2000-02-25 김윤 다당류를이용한대장선택성약물전달조성물및약학제제
IT1303738B1 (it) * 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
IT1303735B1 (it) * 1998-11-11 2001-02-23 Falorni Italia Farmaceutici S Acidi ialuronici reticolati e loro usi medici.
EP1184038B1 (en) 1999-06-09 2005-12-28 Mochida Pharmaceutical Co., Ltd. System for release in lower digestive tract
FR2799196B1 (fr) * 1999-10-04 2002-02-08 Sod Conseils Rech Applic Copolymeres reticules a base de copolymeres polycarboxyliques non reticules
CN1744827B (zh) * 2003-01-31 2010-05-26 帝斯曼知识产权资产管理有限公司 包含类胡萝卜素的新颖的组合物
US7670624B2 (en) 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
GB0607534D0 (en) * 2006-04-13 2006-05-24 Univ London Pharmacy Colonic drug delivery formulation
KR101122845B1 (ko) 2009-07-30 2012-03-21 부산대학교 산학협력단 경구용 염증성 장질환 치료제
BR112014024159A2 (pt) 2012-03-29 2017-06-20 Therabiome Llc Formulações de vacina oral específicas do local gastrintestinal , ativas no íleo e apêndice.
US9907755B2 (en) 2013-03-14 2018-03-06 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
EP3246037A4 (en) 2015-01-16 2018-07-11 Seikagaku Corporation Crosslinked chondroitin sulfate, composition containing same, and treatment agent for eye disease

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7504049L (sv) * 1975-04-09 1976-10-10 Haessle Ab Colonpreparation
DE2717707C3 (de) * 1977-04-21 1979-11-22 Chephasaar Chemisch-Pharmazeutische Fabrik Gmbh, 6670 St Ingbert Karamellisierte Lactulose
US4668517A (en) * 1985-04-04 1987-05-26 Norwich Eaton Pharmaceuticals, Inc. Furazolidone dosage form
ZA881301B (en) * 1987-02-27 1989-10-25 Lilly Co Eli Sustained release matrix formulations
DK110188D0 (da) * 1988-03-02 1988-03-02 Claus Selch Larsen High molecular weight prodrug derivatives of antiinflammatory drugs
US4857331A (en) * 1988-03-31 1989-08-15 Warner-Lambert Company Sugarless pectin delivery system
IT1219942B (it) * 1988-05-13 1990-05-24 Fidia Farmaceutici Esteri polisaccaridici
DE4006521A1 (de) * 1990-03-02 1991-09-05 Bayer Ag Zuckerhaltige polymere zur umhuellung und einbettung von arzneistoffen

Also Published As

Publication number Publication date
EP0527942A4 (en) 1993-10-13
FI924984A (fi) 1992-11-04
JPH05508631A (ja) 1993-12-02
EP0527942A1 (en) 1993-02-24
DE69131688T2 (de) 2000-05-25
CA2082156A1 (en) 1991-11-05
DE527942T1 (de) 1994-03-03
EP0527942B1 (en) 1999-10-06
KR100194161B1 (ko) 1999-06-15
DE69131688D1 (de) 1999-11-11
RU2113221C1 (ru) 1998-06-20
HU210497B (en) 1995-04-28
AU8087791A (en) 1991-11-27
GR3031906T3 (en) 2000-02-29
BR9106419A (pt) 1993-05-04
AU660147B2 (en) 1995-06-15
ES2048133T1 (es) 1994-03-16
ATE185267T1 (de) 1999-10-15
GR940300025T1 (da) 1994-05-31
FI924984A0 (fi) 1992-11-04
WO1991016881A1 (en) 1991-11-14
NO306096B1 (no) 1999-09-20
NO924227L (no) 1992-12-30
HU9203451D0 (en) 1993-05-28
ES2048133T3 (es) 2000-01-16
MC2288A1 (fr) 1993-07-14
NO924227D0 (no) 1992-11-03
HUT64210A (en) 1993-12-28

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