DK0830377T4 - Glucagon-lignende peptid-2 og terapeutisk anvendelse deraf - Google Patents
Glucagon-lignende peptid-2 og terapeutisk anvendelse derafInfo
- Publication number
- DK0830377T4 DK0830377T4 DK96908973.9T DK96908973T DK0830377T4 DK 0830377 T4 DK0830377 T4 DK 0830377T4 DK 96908973 T DK96908973 T DK 96908973T DK 0830377 T4 DK0830377 T4 DK 0830377T4
- Authority
- DK
- Denmark
- Prior art keywords
- glucagon
- peptid
- therapeutic application
- peptide
- bowel
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/605—Glucagons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Obesity (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/422,540 US5990077A (en) | 1995-04-14 | 1995-04-14 | Glucagon-like peptide-2 and its therapeutic use |
PCT/CA1996/000232 WO1996032414A1 (en) | 1995-04-14 | 1996-04-12 | Glucagon-like peptide-2 and its therapeutic use |
Publications (2)
Publication Number | Publication Date |
---|---|
DK0830377T3 DK0830377T3 (da) | 2010-03-01 |
DK0830377T4 true DK0830377T4 (da) | 2013-03-11 |
Family
ID=23675346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96908973.9T DK0830377T4 (da) | 1995-04-14 | 1996-04-12 | Glucagon-lignende peptid-2 og terapeutisk anvendelse deraf |
Country Status (13)
Country | Link |
---|---|
US (1) | US5990077A (da) |
EP (4) | EP2277530A1 (da) |
JP (3) | JPH11505521A (da) |
CN (2) | CN100374461C (da) |
AT (1) | ATE445641T1 (da) |
AU (1) | AU720493B2 (da) |
CA (1) | CA2218225C (da) |
CY (1) | CY2615B2 (da) |
DE (1) | DE69638057D1 (da) |
DK (1) | DK0830377T4 (da) |
ES (1) | ES2334864T5 (da) |
PT (1) | PT830377E (da) |
WO (1) | WO1996032414A1 (da) |
Families Citing this family (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6184201B1 (en) * | 1995-04-14 | 2001-02-06 | Nps Allelix Corp. | Intestinotrophic glucagon-like peptide-2 analogs |
US5834428A (en) * | 1995-04-14 | 1998-11-10 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
US5990077A (en) | 1995-04-14 | 1999-11-23 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
US5912229A (en) * | 1996-03-01 | 1999-06-15 | Novo Nordisk Als | Use of a pharmaceutical composition comprising an appetite-suppressing peptide |
DK1975177T3 (da) | 1996-03-01 | 2011-07-25 | Novo Nordisk As | Appetitundertrykkende peptid, formuleringer dermed og anvendelse deraf |
AU753771B2 (en) * | 1996-04-12 | 2002-10-31 | 1149336 Ontario Inc. | Glucagon-like peptide-2 analogs |
CA2251576C (en) * | 1996-04-12 | 2012-08-21 | 1149336 Ontario Inc. | Glucagon-like peptide-2 analogs |
US5994500A (en) * | 1996-07-19 | 1999-11-30 | 1149336 Ontario Inc. | Antagonists of intestinotrophic GLP-2 peptides |
AU4112497A (en) * | 1996-08-30 | 1998-03-19 | Novo Nordisk A/S | Glp-2 derivatives |
US20020025933A1 (en) * | 1996-08-30 | 2002-02-28 | Knudsen Liselotte Bjerre | GLP-2 derivatives |
US5952301A (en) * | 1996-12-10 | 1999-09-14 | 1149336 Ontario Inc. | Compositions and methods for enhancing intestinal function |
US8592553B2 (en) | 1996-12-13 | 2013-11-26 | Nps Pharmaceuticals, Inc. | Cloned glucagon-like peptide-2 receptors |
AU722821B2 (en) * | 1996-12-13 | 2000-08-10 | Nps Pharmaceuticals, Inc. | Cloned glucagon-like peptide-2 receptors |
CA2236519C (en) * | 1997-05-02 | 2011-09-13 | 1149336 Ontario Inc. | Methods of enhancing functioning of the large intestine |
DE69819488T2 (de) * | 1997-05-16 | 2004-08-26 | 1149336 Ontario Inc., Toronto | Verwendung von glp-2 agonisten zur verbesserung der wirkung des oberen gastrointestinaltraktes |
AU2712899A (en) * | 1998-02-27 | 1999-09-15 | Novo Nordisk A/S | Glp-2 derivatives with helix-content exceeding 25 percent, forming partially structured micellar-like aggregates |
AU3273200A (en) | 1999-03-15 | 2000-10-04 | Novo Nordisk A/S | Ion exchange chromatographic separation of glp-1 and related peptides |
US6451987B1 (en) | 1999-03-15 | 2002-09-17 | Novo Nordisk A/S | Ion exchange chromatography of proteins and peptides |
US6444788B1 (en) | 1999-03-15 | 2002-09-03 | Novo Nordisk A/S | Ion exchange chromatography of GLP-1, analogs and derivatives thereof |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US7186683B2 (en) | 2000-09-18 | 2007-03-06 | Sanos Bioscience A/S | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders |
US20080249016A1 (en) * | 2000-09-18 | 2008-10-09 | Sanos Bioscience A/S | Use of GLP-2 in a combination treatment for bone-related disorders |
US7371721B2 (en) * | 2000-09-18 | 2008-05-13 | Sanos Bioscience A/S | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes |
DK1326630T3 (da) * | 2000-09-18 | 2008-09-15 | Sanos Bioscience As | Anvendelse af GLP-2-peptider |
US20070135345A1 (en) * | 2000-09-18 | 2007-06-14 | Henriksen Dennis B | Use of GLP-2 for the treatment or prevention, of bone-related disorders |
CZ306180B6 (cs) * | 2000-12-07 | 2016-09-14 | Eli Lilly And Company | GLP-1 fúzní proteiny |
EP1360202B1 (en) | 2001-02-16 | 2008-05-21 | ConjuChem Biotechnologies Inc. | Long lasting glucagon-like peptide 2 (glp-2) for the treatment of gastrointestinal diseases and disorders |
EP1894591B1 (en) | 2002-03-20 | 2013-06-26 | MannKind Corporation | Cartridge for an inhalation apparatus |
US7374930B2 (en) * | 2002-05-21 | 2008-05-20 | Expression Genetics, Inc. | GLP-1 gene delivery for the treatment of type 2 diabetes |
US20040038864A1 (en) * | 2002-06-27 | 2004-02-26 | Per Balschmidt | Use of dimethyl sulfone as isotonicity agent |
US20080260838A1 (en) * | 2003-08-01 | 2008-10-23 | Mannkind Corporation | Glucagon-like peptide 1 (glp-1) pharmaceutical formulations |
WO2004035624A2 (en) * | 2002-10-14 | 2004-04-29 | Novo Nordisk A/S | Glucagon - like peptide - 2 variants |
DE602004031927D1 (de) | 2003-02-04 | 2011-05-05 | Novo Nordisk As | Injektionsvorrichtung mit drehbarer dosiseinstellungsvorrichtung |
CA2532340A1 (en) | 2003-08-21 | 2005-03-03 | Novo Nordisk A/S | Separation of polypeptides comprising a racemized amino acid |
ATE550041T1 (de) | 2004-01-21 | 2012-04-15 | Novo Nordisk Healthcare Ag | Transglutaminase-vermittelte konjugation von peptiden |
WO2005082404A2 (en) * | 2004-02-27 | 2005-09-09 | Novo Nordisk A/S | Glp-2 derivatives modified by lipophilic substituents |
DK1786784T3 (da) | 2004-08-20 | 2011-02-14 | Mannkind Corp | Katalyse af diketopiperazinsyntese |
CN104436170B (zh) | 2004-08-23 | 2018-02-23 | 曼金德公司 | 用于药物输送的二酮哌嗪盐 |
WO2006117565A2 (en) * | 2005-05-04 | 2006-11-09 | Zealand Pharma A/S | Glucagon-like-peptide-2 (glp-2) analogues |
CN100418983C (zh) * | 2005-05-11 | 2008-09-17 | 中国药科大学 | 人胰高血糖素相关肽-2类似物 |
HUE028623T2 (en) | 2005-09-14 | 2016-12-28 | Mannkind Corp | Active substance formulation method based on increasing the affinity of the active ingredient for binding to the surface of crystalline microparticles |
IN2015DN00888A (da) | 2006-02-22 | 2015-07-10 | Mannkind Corp | |
UA102506C2 (ru) | 2006-11-08 | 2013-07-25 | Зиланд Фарма А/С | Селективные аналоги глюкагоноподобного пептида-2 (glp-2) |
WO2009055740A2 (en) * | 2007-10-24 | 2009-04-30 | Mannkind Corporation | Method of preventing adverse effects by glp-1 |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
ES2570400T3 (es) | 2008-06-13 | 2016-05-18 | Mannkind Corp | Un inhalador de polvo seco y un sistema para el suministro de fármacos |
JP5479465B2 (ja) | 2008-06-20 | 2014-04-23 | マンカインド コーポレイション | 吸入努力をリアルタイムにプロファイルする対話式機器および方法 |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US20100081622A1 (en) * | 2008-09-29 | 2010-04-01 | Sanos Bioscience A/S | Reduction of parathyroid hormone levels |
HUE037449T2 (hu) | 2008-10-17 | 2018-08-28 | Sanofi Aventis Deutschland | Egy inzulin és egy GLP-1 agonista kombinációja |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
CN102942626B (zh) * | 2009-03-05 | 2015-11-04 | 江苏豪森医药集团有限公司 | 胰高血糖素样肽-2类似物及其制备方法和用途 |
EP2405963B1 (en) | 2009-03-11 | 2013-11-06 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
KR101875969B1 (ko) | 2009-06-12 | 2018-07-06 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
EP2311486A1 (en) * | 2009-10-07 | 2011-04-20 | Nestec S.A. | GLP-2 for use in intestine and muscle recovery |
EP2314616A1 (en) | 2009-10-23 | 2011-04-27 | Ferring B.V. | Peptidic GLP-2 agonists |
JP5784622B2 (ja) | 2009-11-03 | 2015-09-24 | マンカインド コーポレ−ション | 吸入活動をシミュレートするための装置及び方法 |
WO2011058082A1 (de) | 2009-11-13 | 2011-05-19 | Sanofi-Aventis Deutschland Gmbh | Pharmazeutische zusammensetzung umfassend einen glp-1-agonisten und methionin |
AR080669A1 (es) | 2009-11-13 | 2012-05-02 | Sanofi Aventis Deutschland | Composicion farmaceutica que comprende un agonista de glp-1, una insulina y metionina |
CA2797033C (en) | 2010-04-22 | 2021-10-19 | Longevity Biotech, Inc. | Highly active polypeptides and methods of making and using the same |
MX359281B (es) | 2010-06-21 | 2018-09-21 | Mannkind Corp | Sistema y metodos para suministrar un farmaco en polvo seco. |
ES2606554T3 (es) | 2010-08-30 | 2017-03-24 | Sanofi-Aventis Deutschland Gmbh | Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2 |
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US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
BR112014004726A2 (pt) | 2011-08-29 | 2017-04-04 | Sanofi Aventis Deutschland | combinação farmacêutica para uso no controle glicêmico em pacientes de diabetes tipo 2 |
TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
EP3431098A1 (en) * | 2011-09-12 | 2019-01-23 | Amunix Operating Inc. | Glucagon-like peptide-2 compositions and methods of making and using same |
CN103945859A (zh) | 2011-10-24 | 2014-07-23 | 曼金德公司 | 用于治疗疼痛的方法和组合物 |
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EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
AU2014228415B2 (en) | 2013-03-15 | 2018-08-09 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
US9789164B2 (en) | 2013-03-15 | 2017-10-17 | Longevity Biotech, Inc. | Peptides comprising non-natural amino acids and methods of making and using the same |
KR102321339B1 (ko) | 2013-07-18 | 2021-11-02 | 맨카인드 코포레이션 | 열-안정성 건조 분말 약제학적 조성물 및 방법 |
US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
CN104055757B (zh) * | 2014-07-09 | 2016-03-16 | 中国人民解放军第三军医大学第三附属医院 | 胍丁胺用于制备治疗细菌毒素所致小肠结构损害药物的用途 |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
PL3229828T3 (pl) | 2014-12-12 | 2023-07-31 | Sanofi-Aventis Deutschland Gmbh | Formulacja o ustalonym stosunku insuliny glargine/liksysenatydu |
TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
ES2979184T3 (es) | 2016-12-09 | 2024-09-24 | Zealand Pharma As | Agonistas duales de glp-1/glp-2 acilados |
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JPS5186117A (en) | 1975-01-27 | 1976-07-28 | Tanabe Seiyaku Co | Johoseibiryushiseizainoseiho |
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US5990077A (en) | 1995-04-14 | 1999-11-23 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
DK1975177T3 (da) * | 1996-03-01 | 2011-07-25 | Novo Nordisk As | Appetitundertrykkende peptid, formuleringer dermed og anvendelse deraf |
CA2251576C (en) * | 1996-04-12 | 2012-08-21 | 1149336 Ontario Inc. | Glucagon-like peptide-2 analogs |
-
1995
- 1995-04-14 US US08/422,540 patent/US5990077A/en not_active Expired - Lifetime
-
1996
- 1996-04-12 CA CA2218225A patent/CA2218225C/en not_active Expired - Lifetime
- 1996-04-12 EP EP10012215A patent/EP2277530A1/en not_active Withdrawn
- 1996-04-12 CN CNB961946938A patent/CN100374461C/zh not_active Expired - Lifetime
- 1996-04-12 DE DE69638057T patent/DE69638057D1/de not_active Expired - Lifetime
- 1996-04-12 ES ES96908973T patent/ES2334864T5/es not_active Expired - Lifetime
- 1996-04-12 CN CN2008100012906A patent/CN101254300B/zh not_active Expired - Lifetime
- 1996-04-12 PT PT96908973T patent/PT830377E/pt unknown
- 1996-04-12 AU AU52658/96A patent/AU720493B2/en not_active Expired
- 1996-04-12 DK DK96908973.9T patent/DK0830377T4/da active
- 1996-04-12 WO PCT/CA1996/000232 patent/WO1996032414A1/en active Application Filing
- 1996-04-12 JP JP8530606A patent/JPH11505521A/ja not_active Withdrawn
- 1996-04-12 AT AT96908973T patent/ATE445641T1/de active
- 1996-04-12 EP EP96908973A patent/EP0830377B2/en not_active Expired - Lifetime
- 1996-04-12 EP EP10012214A patent/EP2277909A1/en not_active Withdrawn
- 1996-04-12 EP EP08154372.0A patent/EP1988100B1/en not_active Expired - Lifetime
-
2006
- 2006-07-05 JP JP2006185610A patent/JP4496183B2/ja not_active Expired - Lifetime
-
2010
- 2010-01-25 JP JP2010012787A patent/JP5281594B2/ja not_active Expired - Lifetime
-
2011
- 2011-04-15 CY CY1100004A patent/CY2615B2/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JP5281594B2 (ja) | 2013-09-04 |
EP0830377B1 (en) | 2009-10-14 |
CN101254300B (zh) | 2013-05-08 |
CN1188485A (zh) | 1998-07-22 |
DE69638057D1 (de) | 2009-11-26 |
AU720493B2 (en) | 2000-06-01 |
US5990077A (en) | 1999-11-23 |
EP1988100B1 (en) | 2015-03-04 |
JP4496183B2 (ja) | 2010-07-07 |
PT830377E (pt) | 2010-01-19 |
JPH11505521A (ja) | 1999-05-21 |
EP0830377A1 (en) | 1998-03-25 |
DK0830377T3 (da) | 2010-03-01 |
CA2218225C (en) | 2014-09-23 |
JP2006342172A (ja) | 2006-12-21 |
EP0830377B2 (en) | 2012-12-12 |
WO1996032414A1 (en) | 1996-10-17 |
ATE445641T1 (de) | 2009-10-15 |
EP2277530A1 (en) | 2011-01-26 |
EP2277909A1 (en) | 2011-01-26 |
MX9707949A (es) | 1998-06-30 |
JP2010159259A (ja) | 2010-07-22 |
EP1988100A1 (en) | 2008-11-05 |
CN101254300A (zh) | 2008-09-03 |
AU5265896A (en) | 1996-10-30 |
CA2218225A1 (en) | 1996-10-17 |
CY2615B2 (en) | 2012-01-25 |
ES2334864T3 (es) | 2010-03-16 |
CN100374461C (zh) | 2008-03-12 |
ES2334864T5 (es) | 2013-04-08 |
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