DK0525861T3 - Fremgangsmåde til enzymatisk fremstilling af 7-aminocephalosporansyrer - Google Patents

Fremgangsmåde til enzymatisk fremstilling af 7-aminocephalosporansyrer

Info

Publication number
DK0525861T3
DK0525861T3 DK92202159.7T DK92202159T DK0525861T3 DK 0525861 T3 DK0525861 T3 DK 0525861T3 DK 92202159 T DK92202159 T DK 92202159T DK 0525861 T3 DK0525861 T3 DK 0525861T3
Authority
DK
Denmark
Prior art keywords
acids
aminocephalosporanoic
enzymatic preparation
chem
formula
Prior art date
Application number
DK92202159.7T
Other languages
English (en)
Inventor
Ezio Battistel
Pietro Cesti
Giuliana Franzosi
Wilhelmus Van Der Goes
Original Assignee
Mini Ricerca Scient Tecnolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mini Ricerca Scient Tecnolog filed Critical Mini Ricerca Scient Tecnolog
Application granted granted Critical
Publication of DK0525861T3 publication Critical patent/DK0525861T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/025—Achromobacter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/834—Bacillus cereus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK92202159.7T 1991-07-24 1992-07-15 Fremgangsmåde til enzymatisk fremstilling af 7-aminocephalosporansyrer DK0525861T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912039A IT1250698B (it) 1991-07-24 1991-07-24 Processo per la preparazione enzimatica di acidi 7-ammino-cefalosporanici.

Publications (1)

Publication Number Publication Date
DK0525861T3 true DK0525861T3 (da) 1997-03-17

Family

ID=11360414

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92202159.7T DK0525861T3 (da) 1991-07-24 1992-07-15 Fremgangsmåde til enzymatisk fremstilling af 7-aminocephalosporansyrer

Country Status (10)

Country Link
US (1) US5332663A (da)
EP (1) EP0525861B1 (da)
JP (1) JP3195058B2 (da)
AT (1) ATE144794T1 (da)
CA (1) CA2074032A1 (da)
DE (1) DE69214891T2 (da)
DK (1) DK0525861T3 (da)
ES (1) ES2094278T3 (da)
GR (1) GR3022044T3 (da)
IT (1) IT1250698B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100345994B1 (ko) * 1994-06-22 2002-12-16 제일제당주식회사 7-아미노세팔로스포란산의효소적제조방법
US5766871A (en) * 1996-11-27 1998-06-16 Food Industry Research And Development Institute Screening and characterization of glutaryl-7-aminocephalosporanic acid acylase
DE19924632B4 (de) 1999-05-28 2006-04-13 Sanofi-Aventis Deutschland Gmbh Verfahren zur Verzögerung der Desaktivierung von Glutarylamidase während einer Enzymkatalyse
CA2423161A1 (en) 2000-09-22 2002-03-28 Bristol-Myers Squibb Company Glutaryl cephalosporin amidase from pseudomonas diminuta bs-203

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1357977A (fr) * 1963-05-20 1964-04-10 Merck & Co Inc Procédé de production d'acide 7-aminocéphalosphalosporanique par voie enzymatique
CH475284A (de) * 1963-11-19 1969-07-15 Ciba Geigy Verfahren zur Herstellung von Desacetyl-7-amino-cephalosporansäure
US3239394A (en) * 1964-06-15 1966-03-08 Merck & Co Inc Process for producing 7-amino-cephalosporanic acid
CH590292A5 (da) * 1973-12-20 1977-07-29 Ciba Geigy Ag
DK158316C (da) * 1974-01-23 1990-10-08 Toyo Jozo Kk Fremgangsmaade til fremstilling af 3-substituerede 7-amino-3-cephem-4-carboxylsyrederivater
JPS5619999B2 (da) * 1974-02-07 1981-05-11
JPS5671092A (en) * 1979-11-14 1981-06-13 Kyowa Hakko Kogyo Co Ltd Optical active cephalosporin analogous derivative
NO155547C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Optisk aktive cefalosporin-analoge og salter derav samt fremgangsmaate for deres fremstilling.
JPS6121097A (ja) * 1984-07-10 1986-01-29 Asahi Chem Ind Co Ltd ７−アミノセフアロスポラン酸及びその誘導体の製造法
EP0275901B1 (de) * 1987-01-17 1993-06-09 Hoechst Aktiengesellschaft Verwendung von Gamma-Glutamyl-Transpeptidase
EP0322032A3 (en) * 1987-12-21 1991-01-30 Merck & Co. Inc. One-step enzymatic conversion of cephalosporin c and derivatives to 7-aminocephalosporanic acid and derivatives
US5104800A (en) * 1989-06-27 1992-04-14 Merck & Co., Inc. One-step cephalosporin c amidase enzyme
CA2040707C (en) * 1990-04-27 2002-07-09 Kenji Mitsushima Cephalosporin acetylhydrolase gene and protein encoded by said gene
JPH088877B2 (ja) * 1990-06-19 1996-01-31 塩野義製薬株式会社 デアセチル―７―アミノセファロスポラン酸の製造法
JPH04104792A (ja) * 1990-08-22 1992-04-07 Asahi Chem Ind Co Ltd 新規アクレモニウム・クリソゲナム
GB9019724D0 (en) * 1990-09-10 1990-10-24 Fujisawa Pharmaceutical Co Cephalosporin c acylase
IT1252308B (it) * 1990-12-21 1995-06-08 Antibioticos Spa Procedimento enzimatico per la produzione di acido 7- amminocefalosporanico e derivati

Also Published As

Publication number Publication date
DE69214891D1 (de) 1996-12-05
ITMI912039A0 (it) 1991-07-24
ES2094278T3 (es) 1997-01-16
EP0525861B1 (en) 1996-10-30
JPH05211889A (ja) 1993-08-24
CA2074032A1 (en) 1993-01-25
EP0525861A1 (en) 1993-02-03
ATE144794T1 (de) 1996-11-15
IT1250698B (it) 1995-04-21
GR3022044T3 (en) 1997-03-31
DE69214891T2 (de) 1997-05-15
JP3195058B2 (ja) 2001-08-06
ITMI912039A1 (it) 1993-01-25
US5332663A (en) 1994-07-26

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