DK0524579T3 - Forbedrede orale dosisformuleringer af dideoxypurinnukleosider - Google Patents

Forbedrede orale dosisformuleringer af dideoxypurinnukleosider

Info

Publication number
DK0524579T3
DK0524579T3 DK92112371.7T DK92112371T DK0524579T3 DK 0524579 T3 DK0524579 T3 DK 0524579T3 DK 92112371 T DK92112371 T DK 92112371T DK 0524579 T3 DK0524579 T3 DK 0524579T3
Authority
DK
Denmark
Prior art keywords
oral dosage
improved oral
dosage formulations
reduced mass
dideoxypurnucleosides
Prior art date
Application number
DK92112371.7T
Other languages
Danish (da)
English (en)
Inventor
Ismat Ullah
Shreeram Narahari Agharkar
Gary James Wiley
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27112590&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0524579(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK0524579T3 publication Critical patent/DK0524579T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12—Magnesium silicate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
DK92112371.7T 1991-07-22 1992-07-20 Forbedrede orale dosisformuleringer af dideoxypurinnukleosider DK0524579T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73354791A 1991-07-22 1991-07-22
US88220492A 1992-05-13 1992-05-13

Publications (1)

Publication Number Publication Date
DK0524579T3 true DK0524579T3 (da) 1998-04-06

Family

ID=27112590

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92112371.7T DK0524579T3 (da) 1991-07-22 1992-07-20 Forbedrede orale dosisformuleringer af dideoxypurinnukleosider

Country Status (23)

Country Link
US (1) US5880106A (de)
EP (1) EP0524579B1 (de)
JP (1) JP3038456B2 (de)
KR (1) KR960011772B1 (de)
CN (1) CN1042299C (de)
AT (1) ATE163855T1 (de)
AU (1) AU657337B2 (de)
CA (1) CA2074215C (de)
DE (1) DE69224684T2 (de)
DK (1) DK0524579T3 (de)
ES (1) ES2113389T3 (de)
FI (1) FI105153B (de)
GR (1) GR3026332T3 (de)
HU (3) HU9202318D0 (de)
IE (1) IE922365A1 (de)
IL (1) IL102519A (de)
MX (1) MX9204256A (de)
NO (1) NO300198B1 (de)
NZ (1) NZ243567A (de)
PL (1) PL295329A1 (de)
RU (1) RU2089193C1 (de)
TW (1) TW211521B (de)
ZA (1) ZA925484B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122207B2 (en) * 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
UA69413C2 (uk) * 1998-05-22 2004-09-15 Брістол-Майерс Сквібб Компані Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції
IL134592A0 (en) * 1998-06-18 2001-04-30 Univ George Washington Compositions comprising camptothecin compounds for the treatment of cancer with reduced side effects
UA73092C2 (uk) * 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
US6174873B1 (en) * 1998-11-04 2001-01-16 Supergen, Inc. Oral administration of adenosine analogs
US20040028772A1 (en) * 2000-08-14 2004-02-12 Carsten Andersen Method for preparation of chewing gum with customer acceptable taste
US6887926B1 (en) 2001-11-16 2005-05-03 Oatey Co. Bonding compositions for chlorinated polymers and methods of using the same
CN100415211C (zh) * 2003-07-03 2008-09-03 上海现代药物制剂工程研究中心 抗艾滋病药去羟肌苷的肠溶微粒组合物及制备方法
US20080299227A1 (en) * 2007-05-30 2008-12-04 Sunhealth Therapies, Inc. Method for removal of HIV from the gastrointestinal tract and bile of HIV-infected subjects and for the prevention of drug failure and prevention of development of AIDS in HIV-infected subjects
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
EA201100851A1 (ru) 2008-12-23 2012-04-30 Фармассет, Инк. Аналоги нуклеозидов
CL2009002206A1 (es) 2008-12-23 2011-08-26 Gilead Pharmasset Llc Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
NZ593648A (en) 2008-12-23 2013-09-27 Gilead Pharmasset Llc Nucleoside phosphoramidates
TWI576352B (zh) 2009-05-20 2017-04-01 基利法瑪席特有限責任公司 核苷磷醯胺
BR112012024884A2 (pt) 2010-03-31 2016-10-18 Gilead Pharmasset Llc síntese estereosseletiva de ativos contendo fósforo
US8563530B2 (en) 2010-03-31 2013-10-22 Gilead Pharmassel LLC Purine nucleoside phosphoramidate
EP2609923B1 (de) 2010-03-31 2017-05-24 Gilead Pharmasset LLC Verfahren zur krystallisierung von (s)-isopropyl 2-(((s)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoat
EP2428201A1 (de) 2010-09-08 2012-03-14 Merck Serono S.A. Orale Verabreichung von Nukleosidmonophosphaten
AR084044A1 (es) 2010-11-30 2013-04-17 Pharmasset Inc Compuestos 2’-espiro-nucleosidos
CN102949406B (zh) * 2011-08-31 2014-03-12 天津药物研究院 一种复方艾夫他滨药物组合物及其制备方法和用途
AR089857A1 (es) * 2012-02-02 2014-09-24 Glaxosmithkline Llc Comprimido antiacido para refrescar el aliento
ES2821528T3 (es) 2012-11-14 2021-04-26 Grace W R & Co Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado
CN104069126A (zh) * 2014-07-02 2014-10-01 浙江康乐药业股份有限公司 一种治疗胃酸过多的药物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260596A (en) * 1979-08-13 1981-04-07 Bristol-Myers Company Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same
US4339428A (en) * 1980-08-18 1982-07-13 Bristol-Myers Company Capsule product containing high dosage of aspirin in powder or granulated form and alkaline tablet or pellet comprising magnesium carbonate, calcium carbonate and a magnesium dry component
CA1239349A (en) * 1983-10-10 1988-07-19 Eberhard F. Gottwald Pharmaceutical composition containing cimetidine
JPS62501712A (ja) * 1985-08-26 1987-07-09 アメリカ合衆国 ２′、３′―ジデオキシイノシン、２′，３′―ジデオキシグアノシンまたは２′，３′―ジデオキシアデノシンを含有する抗ｈｔｌｖ―３／ｌａｖ剤
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
CH674148A5 (de) * 1986-06-24 1990-05-15 Racz Istvan
WO1988002629A1 (en) * 1986-10-16 1988-04-21 American Health Products Corporation 2',3'-didesoxyadenosine composition
US4935243A (en) * 1988-12-19 1990-06-19 Pharmacaps, Inc. Chewable, edible soft gelatin capsule
US5026687A (en) * 1990-01-03 1991-06-25 The United States Of America As Represented By The Department Of Health And Human Services Treatment of human retroviral infections with 2',3'-dideoxyinosine alone and in combination with other antiviral compounds

Also Published As

Publication number Publication date
GR3026332T3 (en) 1998-06-30
EP0524579A1 (de) 1993-01-27
PL295329A1 (en) 1993-04-05
ES2113389T3 (es) 1998-05-01
CA2074215C (en) 2001-12-18
NZ243567A (en) 1995-04-27
HU9202375D0 (en) 1992-10-28
KR930001912A (ko) 1993-02-22
MX9204256A (es) 1993-01-01
NO922807L (no) 1993-01-25
US5880106A (en) 1999-03-09
TW211521B (de) 1993-08-21
AU657337B2 (en) 1995-03-09
RU2089193C1 (ru) 1997-09-10
FI923308A (fi) 1993-01-23
HU211285A9 (en) 1995-11-28
HU220612B1 (hu) 2002-03-28
AU2039692A (en) 1993-01-28
NO922807D0 (no) 1992-07-16
CN1042299C (zh) 1999-03-03
JPH05194234A (ja) 1993-08-03
HUT61472A (en) 1993-01-28
KR960011772B1 (ko) 1996-08-30
NO300198B1 (no) 1997-04-28
HU9202318D0 (en) 1992-10-28
CA2074215A1 (en) 1993-01-23
FI923308A0 (fi) 1992-07-20
IL102519A (en) 1996-01-31
DE69224684D1 (de) 1998-04-16
FI105153B (fi) 2000-06-30
IE922365A1 (en) 1992-11-18
DE69224684T2 (de) 1998-11-12
IL102519A0 (en) 1993-01-14
CN1068739A (zh) 1993-02-10
JP3038456B2 (ja) 2000-05-08
ZA925484B (en) 1993-09-13
ATE163855T1 (de) 1998-03-15
EP0524579B1 (de) 1998-03-11

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