DK0458696T3 - Anvendelse af 1-(2-naphtylethyl)-4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridin til fremstilling af et lægemiddel til behandling af cerebrale og neuronale sygdomme - Google Patents
Anvendelse af 1-(2-naphtylethyl)-4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridin til fremstilling af et lægemiddel til behandling af cerebrale og neuronale sygdommeInfo
- Publication number
- DK0458696T3 DK0458696T3 DK91401311.5T DK91401311T DK0458696T3 DK 0458696 T3 DK0458696 T3 DK 0458696T3 DK 91401311 T DK91401311 T DK 91401311T DK 0458696 T3 DK0458696 T3 DK 0458696T3
- Authority
- DK
- Denmark
- Prior art keywords
- naphthylethyl
- tetrahydropyridine
- trifluoromethylphenyl
- cerebral
- medicament
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9006399A FR2662355B1 (fr) | 1990-05-22 | 1990-05-22 | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0458696T3 true DK0458696T3 (da) | 1996-05-20 |
Family
ID=9396855
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK91401311.5T DK0458696T3 (da) | 1990-05-22 | 1991-05-21 | Anvendelse af 1-(2-naphtylethyl)-4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridin til fremstilling af et lægemiddel til behandling af cerebrale og neuronale sygdomme |
DK94403014T DK0655247T3 (da) | 1990-05-22 | 1991-05-21 | Anvendelse af vinkristin til bestemmelse af substanser på neuralt niveau |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94403014T DK0655247T3 (da) | 1990-05-22 | 1991-05-21 | Anvendelse af vinkristin til bestemmelse af substanser på neuralt niveau |
Country Status (17)
Country | Link |
---|---|
US (3) | US5229389A (ja) |
EP (2) | EP0458696B1 (ja) |
JP (2) | JP2618115B2 (ja) |
KR (1) | KR0181330B1 (ja) |
AT (2) | ATE207747T1 (ja) |
BR (1) | BR9105015A (ja) |
CA (2) | CA2042974C (ja) |
CY (1) | CY2283B1 (ja) |
DE (2) | DE69132797T2 (ja) |
DK (2) | DK0458696T3 (ja) |
FR (1) | FR2662355B1 (ja) |
HK (1) | HK1001471A1 (ja) |
HU (1) | HU208922B (ja) |
IE (1) | IE911707A1 (ja) |
IL (3) | IL112167A (ja) |
TW (1) | TW216771B (ja) |
ZA (1) | ZA913865B (ja) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0192386A (ja) * | 1987-10-05 | 1989-04-11 | Hitachi Ltd | 密閉循環型吸収式冷凍機及び吸収式冷凍機用吸収液 |
FR2662355B1 (fr) * | 1990-05-22 | 1994-11-10 | Sanofi Sa | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
US5618822A (en) * | 1990-05-23 | 1997-04-08 | Sanofi | N-substituted trifluoromethylphenyltetrahydropyridines, process for the preparation thereof, intermediates in said process and pharmaceutical compositions containing them |
FR2662442A1 (fr) * | 1990-05-23 | 1991-11-29 | Midy Spa | Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant. |
US5557209A (en) * | 1990-12-20 | 1996-09-17 | Hewlett-Packard Company | Identification of pin-open faults by capacitive coupling through the integrated circuit package |
FR2690158B1 (fr) * | 1992-04-17 | 1994-07-22 | Sanofi Elf | Nouveau derive arylpiperidinique, procede pour sa preparation et compositions pharmaceutiques le contenant. |
FR2702656B1 (fr) * | 1993-03-18 | 1995-06-16 | Sanofi Elf | Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments cardioprotecteurs. |
US5698565A (en) * | 1995-06-09 | 1997-12-16 | Hoffmann-La Roche Inc. | Use of phenoxy-pyridine derivatives |
FR2736053B1 (fr) * | 1995-06-28 | 1997-09-19 | Sanofi Sa | Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines |
CA2235747C (en) * | 1995-10-26 | 2006-01-03 | Sanofi | Use of 1-(2-naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine for preparing drugs for treating amyotrophic lateral sclerosis |
FR2740343B1 (fr) * | 1995-10-26 | 1999-01-22 | Sanofi Sa | Utilisation de la 1-(2-napht-2-yl-ethyl)-4- (3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de la sclerose laterale amyotrophique |
DE69736976T2 (de) * | 1996-03-29 | 2007-10-18 | Trustees Of Boston University, Boston | Mit Alzheimer Krankheit verknüpften Verfahren zur Diagnose, zur Herstellung von Medikamenten und zum Screenen von Substanzen sowie aus Beta-Amyloid abgeleiteten Peptiden |
US5891465A (en) * | 1996-05-14 | 1999-04-06 | Biozone Laboratories, Inc. | Delivery of biologically active material in a liposomal formulation for administration into the mouth |
FR2757160B1 (fr) * | 1996-12-13 | 1999-03-12 | Sanofi Sa | 1-phenylalkyl-1,2,3,6-tetrahydropyridines |
FR2757161B1 (fr) * | 1996-12-13 | 1999-03-12 | Sanofi Sa | Diphenylalkyl-tetrahydropyridines |
FR2757510B1 (fr) * | 1996-12-23 | 2000-01-07 | Sanofi Sa | Forme microparticulaire d'un derive de tetrahydropyridine |
FR2757512B1 (fr) | 1996-12-24 | 1999-03-12 | Sanofi Sa | Utilisation de benzoylalkyl-1-1,2,3,6-tetrahydropyridines |
CA2279326A1 (fr) * | 1997-02-03 | 1998-08-06 | Sanofi-Synthelabo | Utilisation du 1-[4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyrid-1yl]-2-(6,7-dimethoxynapht-2-yl)ethane pour la preparation de medicaments destines aux traitements de troubles cerebraux et neuronaux |
FR2762514B1 (fr) | 1997-04-29 | 1999-10-22 | Sanofi Sa | Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation |
FR2763847B1 (fr) * | 1997-05-28 | 2003-06-06 | Sanofi Sa | Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1 |
FR2771007B1 (fr) * | 1997-11-14 | 2000-12-01 | Sanofi Sa | Association de principes actifs pour le traitement de la demence senile du type alzheimer |
CO4980891A1 (es) * | 1997-11-14 | 2000-11-27 | Sanofi Sa | Asociacion de principios activos para el tratamiento de la demencia senil de tipo azheimer |
DE19751949A1 (de) | 1997-11-24 | 1999-05-27 | Bayer Ag | Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration |
TWI237035B (en) * | 1998-07-24 | 2005-08-01 | Polyplastics Co | Polyacetal copolymer |
KR101130212B1 (ko) * | 2002-03-27 | 2012-04-13 | 파이토팜 피엘씨 | 사포게닌 및 그 유도체의 치료 방법 및 사용법 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2531707A1 (fr) * | 1982-08-16 | 1984-02-17 | Midy Spa | Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques |
FR2639226B1 (fr) * | 1988-11-18 | 1993-11-05 | Sanofi | Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs |
FR2662355B1 (fr) * | 1990-05-22 | 1994-11-10 | Sanofi Sa | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
-
1990
- 1990-05-22 FR FR9006399A patent/FR2662355B1/fr not_active Expired - Lifetime
-
1991
- 1991-05-17 IL IL11216791A patent/IL112167A/en not_active IP Right Cessation
- 1991-05-17 IL IL9817591A patent/IL98175A/en not_active IP Right Cessation
- 1991-05-20 TW TW080103889A patent/TW216771B/zh not_active IP Right Cessation
- 1991-05-20 IE IE170791A patent/IE911707A1/en not_active IP Right Cessation
- 1991-05-21 DE DE69132797T patent/DE69132797T2/de not_active Expired - Fee Related
- 1991-05-21 DK DK91401311.5T patent/DK0458696T3/da active
- 1991-05-21 AT AT94403014T patent/ATE207747T1/de not_active IP Right Cessation
- 1991-05-21 CA CA002042974A patent/CA2042974C/en not_active Expired - Lifetime
- 1991-05-21 DE DE69115989T patent/DE69115989T2/de not_active Expired - Lifetime
- 1991-05-21 CA CA002365832A patent/CA2365832C/en not_active Expired - Fee Related
- 1991-05-21 EP EP91401311A patent/EP0458696B1/fr not_active Expired - Lifetime
- 1991-05-21 AT AT91401311T patent/ATE132369T1/de not_active IP Right Cessation
- 1991-05-21 DK DK94403014T patent/DK0655247T3/da active
- 1991-05-21 US US07/703,835 patent/US5229389A/en not_active Expired - Lifetime
- 1991-05-21 EP EP94403014A patent/EP0655247B1/fr not_active Expired - Lifetime
- 1991-05-22 HU HU911729A patent/HU208922B/hu unknown
- 1991-05-22 KR KR1019910008272A patent/KR0181330B1/ko not_active IP Right Cessation
- 1991-05-22 ZA ZA913865A patent/ZA913865B/xx unknown
- 1991-05-22 JP JP3146949A patent/JP2618115B2/ja not_active Expired - Lifetime
- 1991-11-07 US US07/789,044 patent/US5270320A/en not_active Expired - Lifetime
- 1991-11-19 BR BR919105015A patent/BR9105015A/pt not_active Application Discontinuation
-
1993
- 1993-10-20 US US08/142,069 patent/US5468753A/en not_active Expired - Lifetime
-
1994
- 1994-12-27 IL IL11216794A patent/IL112167A0/xx unknown
-
1996
- 1996-08-20 JP JP8218926A patent/JP2954029B2/ja not_active Expired - Fee Related
-
1998
- 1998-01-20 HK HK98100449A patent/HK1001471A1/xx not_active IP Right Cessation
-
2002
- 2002-05-15 CY CY0200037A patent/CY2283B1/xx unknown
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