DE812812C - Verfahren zur Herstellung von therapeutisch wertvollen, Calcium enthaltenden Suppositorien - Google Patents
Verfahren zur Herstellung von therapeutisch wertvollen, Calcium enthaltenden SuppositorienInfo
- Publication number
- DE812812C DE812812C DE1950W0001695 DEW0001695A DE812812C DE 812812 C DE812812 C DE 812812C DE 1950W0001695 DE1950W0001695 DE 1950W0001695 DE W0001695 A DEW0001695 A DE W0001695A DE 812812 C DE812812 C DE 812812C
- Authority
- DE
- Germany
- Prior art keywords
- calcium
- suppository
- cocoa butter
- melted
- suppositories
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000829 suppository Substances 0.000 title claims description 19
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims description 14
- 239000011575 calcium Substances 0.000 title claims description 14
- 229910052791 calcium Inorganic materials 0.000 title claims description 14
- 238000000034 method Methods 0.000 title claims description 7
- 159000000007 calcium salts Chemical class 0.000 claims description 9
- 229940110456 cocoa butter Drugs 0.000 claims description 9
- 235000019868 cocoa butter Nutrition 0.000 claims description 9
- 239000002511 suppository base Substances 0.000 claims description 7
- 229930003316 Vitamin D Natural products 0.000 claims description 6
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 6
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 6
- 229930195729 fatty acid Natural products 0.000 claims description 6
- 239000000194 fatty acid Substances 0.000 claims description 6
- 150000004665 fatty acids Chemical class 0.000 claims description 6
- 235000019166 vitamin D Nutrition 0.000 claims description 6
- 239000011710 vitamin D Substances 0.000 claims description 6
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 6
- 229940046008 vitamin d Drugs 0.000 claims description 6
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 4
- 239000000155 melt Substances 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 claims description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 2
- 102000003982 Parathyroid hormone Human genes 0.000 claims description 2
- 108090000445 Parathyroid hormone Proteins 0.000 claims description 2
- 229930003268 Vitamin C Natural products 0.000 claims description 2
- 239000003613 bile acid Substances 0.000 claims description 2
- 230000003913 calcium metabolism Effects 0.000 claims description 2
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000000199 parathyroid hormone Substances 0.000 claims description 2
- 229960001319 parathyroid hormone Drugs 0.000 claims description 2
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 claims description 2
- 235000005493 rutin Nutrition 0.000 claims description 2
- IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 claims description 2
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 claims description 2
- 229960004555 rutoside Drugs 0.000 claims description 2
- 235000019154 vitamin C Nutrition 0.000 claims description 2
- 239000011718 vitamin C Substances 0.000 claims description 2
- CBOCVOKPQGJKKJ-UHFFFAOYSA-L Calcium formate Chemical compound [Ca+2].[O-]C=O.[O-]C=O CBOCVOKPQGJKKJ-UHFFFAOYSA-L 0.000 claims 2
- 229940044172 calcium formate Drugs 0.000 claims 2
- 235000019255 calcium formate Nutrition 0.000 claims 2
- 239000004281 calcium formate Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 229960005069 calcium Drugs 0.000 description 11
- VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 description 7
- 229960005147 calcium acetate Drugs 0.000 description 7
- 239000001639 calcium acetate Substances 0.000 description 7
- 235000011092 calcium acetate Nutrition 0.000 description 7
- 150000003839 salts Chemical class 0.000 description 5
- BCZXFFBUYPCTSJ-UHFFFAOYSA-L Calcium propionate Chemical compound [Ca+2].CCC([O-])=O.CCC([O-])=O BCZXFFBUYPCTSJ-UHFFFAOYSA-L 0.000 description 4
- 235000010331 calcium propionate Nutrition 0.000 description 4
- 239000004330 calcium propionate Substances 0.000 description 4
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 description 3
- 229960002401 calcium lactate Drugs 0.000 description 3
- 239000001527 calcium lactate Substances 0.000 description 3
- 235000011086 calcium lactate Nutrition 0.000 description 3
- FYPVXEILSNEKOO-UHFFFAOYSA-L calcium;butanoate Chemical compound [Ca+2].CCCC([O-])=O.CCCC([O-])=O FYPVXEILSNEKOO-UHFFFAOYSA-L 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000002253 acid Substances 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 239000000654 additive Substances 0.000 description 1
- 229940043430 calcium compound Drugs 0.000 description 1
- 150000001674 calcium compounds Chemical class 0.000 description 1
- 229960004494 calcium gluconate Drugs 0.000 description 1
- 239000004227 calcium gluconate Substances 0.000 description 1
- 235000013927 calcium gluconate Nutrition 0.000 description 1
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE502552D BE502552A (enrdf_load_stackoverflow) | 1950-04-18 | ||
| NL75009D NL75009C (enrdf_load_stackoverflow) | 1950-04-18 | ||
| DE1950W0001695 DE812812C (de) | 1950-04-18 | 1950-04-18 | Verfahren zur Herstellung von therapeutisch wertvollen, Calcium enthaltenden Suppositorien |
| FR1055846D FR1055846A (fr) | 1950-04-18 | 1951-04-17 | Procédé pour la préparation de suppositoires au calciun? de grande valeur thérapeutique |
| GB898751A GB689722A (en) | 1950-04-18 | 1951-04-17 | Process for the production of suppositories containing therapeutically valuable calcium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1950W0001695 DE812812C (de) | 1950-04-18 | 1950-04-18 | Verfahren zur Herstellung von therapeutisch wertvollen, Calcium enthaltenden Suppositorien |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE812812C true DE812812C (de) | 1951-09-06 |
Family
ID=7591325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE1950W0001695 Expired DE812812C (de) | 1950-04-18 | 1950-04-18 | Verfahren zur Herstellung von therapeutisch wertvollen, Calcium enthaltenden Suppositorien |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE502552A (enrdf_load_stackoverflow) |
| DE (1) | DE812812C (enrdf_load_stackoverflow) |
| FR (1) | FR1055846A (enrdf_load_stackoverflow) |
| GB (1) | GB689722A (enrdf_load_stackoverflow) |
| NL (1) | NL75009C (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0612519A1 (en) * | 1993-02-23 | 1994-08-31 | Wolfgang Dr. Werner | Calcium formulation for treating milk cows suffering from hypocalcemia |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2790746A (en) * | 1954-01-29 | 1957-04-30 | Souza Seabra & Cia Ltda | Anti-rheumatic mixture and method of preparing |
| US6241997B1 (en) * | 1998-03-16 | 2001-06-05 | Smtm Group. Llc | Chewable calcium supplement and method |
-
0
- NL NL75009D patent/NL75009C/xx active
- BE BE502552D patent/BE502552A/xx unknown
-
1950
- 1950-04-18 DE DE1950W0001695 patent/DE812812C/de not_active Expired
-
1951
- 1951-04-17 GB GB898751A patent/GB689722A/en not_active Expired
- 1951-04-17 FR FR1055846D patent/FR1055846A/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0612519A1 (en) * | 1993-02-23 | 1994-08-31 | Wolfgang Dr. Werner | Calcium formulation for treating milk cows suffering from hypocalcemia |
Also Published As
| Publication number | Publication date |
|---|---|
| GB689722A (en) | 1953-04-01 |
| BE502552A (enrdf_load_stackoverflow) | |
| FR1055846A (fr) | 1954-02-22 |
| NL75009C (enrdf_load_stackoverflow) |
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