DE69939021D1 - N-(iminomethyl)amin-derivate, ihre herstellung, ihre verwendung in medikamenten und sie enthaltende pharmazeutische zubereitungen - Google Patents

N-(iminomethyl)amin-derivate, ihre herstellung, ihre verwendung in medikamenten und sie enthaltende pharmazeutische zubereitungen

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Publication number
DE69939021D1
DE69939021D1 DE69939021T DE69939021T DE69939021D1 DE 69939021 D1 DE69939021 D1 DE 69939021D1 DE 69939021 T DE69939021 T DE 69939021T DE 69939021 T DE69939021 T DE 69939021T DE 69939021 D1 DE69939021 D1 DE 69939021D1
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Germany
Prior art keywords
iminomethyl
medicaments
preparation
pharmaceutical preparations
preparations containing
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Expired - Lifetime
Application number
DE69939021T
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English (en)
Inventor
Dennis Bigg
De Lassauniere Pierre Chabrier
Serge Auvin
Jeremiah Harnett
Gerard Ulibarri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P37/02—Immunomodulators
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
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  • Communicable Diseases (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
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  • Urology & Nephrology (AREA)
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DE69939021T 1998-09-23 1999-09-22 N-(iminomethyl)amin-derivate, ihre herstellung, ihre verwendung in medikamenten und sie enthaltende pharmazeutische zubereitungen Expired - Lifetime DE69939021D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9811867A FR2784678B1 (fr) 1998-09-23 1998-09-23 Nouveaux derives de n-(iminomethyl)amines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
PCT/FR1999/002251 WO2000017191A2 (fr) 1998-09-23 1999-09-22 Derives de n-(iminomethyl)amines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
DE69939021D1 true DE69939021D1 (de) 2008-08-14

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DE69939021T Expired - Lifetime DE69939021D1 (de) 1998-09-23 1999-09-22 N-(iminomethyl)amin-derivate, ihre herstellung, ihre verwendung in medikamenten und sie enthaltende pharmazeutische zubereitungen

Country Status (26)

Country Link
US (5) US6482822B1 (de)
EP (1) EP1115720B1 (de)
JP (1) JP2003517444A (de)
KR (1) KR100655340B1 (de)
CN (1) CN1144799C (de)
AR (1) AR024837A1 (de)
AT (1) ATE399774T1 (de)
AU (1) AU759958B2 (de)
BR (1) BR9913899A (de)
CA (1) CA2344223A1 (de)
CZ (1) CZ299664B6 (de)
DE (1) DE69939021D1 (de)
DK (1) DK1115720T3 (de)
ES (1) ES2310045T3 (de)
FR (1) FR2784678B1 (de)
HK (1) HK1043365B (de)
HU (1) HUP0104013A3 (de)
IL (2) IL141997A0 (de)
MY (1) MY123219A (de)
NO (1) NO328466B1 (de)
NZ (1) NZ511188A (de)
PL (1) PL347471A1 (de)
PT (1) PT1115720E (de)
RU (1) RU2230742C2 (de)
WO (1) WO2000017191A2 (de)
ZA (1) ZA200103206B (de)

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KR20080044273A (ko) 2005-08-08 2008-05-20 아스텔라스세이야쿠 가부시키가이샤 아실구아니딘 유도체 또는 그의 염
KR20140057409A (ko) * 2005-09-02 2014-05-12 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한 (＋)-1,4-디히드로-7-［(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리디닐］-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
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US20050027009A1 (en) 2005-02-03
US6809090B2 (en) 2004-10-26
HK1043365A1 (en) 2002-09-13
NZ511188A (en) 2003-08-29
KR20010085832A (ko) 2001-09-07
AU759958B2 (en) 2003-05-01
CN1335841A (zh) 2002-02-13
IL141997A0 (en) 2002-03-10
NO20011478L (no) 2001-03-22
EP1115720A2 (de) 2001-07-18
US6620840B1 (en) 2003-09-16
ES2310045T3 (es) 2008-12-16
KR100655340B1 (ko) 2006-12-08
US7186752B2 (en) 2007-03-06
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Owner name: IPSEN PHARMA S.A.S., BOULOGNE-BILLANCOURT, FR