DE69933172D1 - Verfahren zur Herstellung einer optisch aktiven N-substituierten Azetidin-2-carbonsäure-Verbindung - Google Patents

Verfahren zur Herstellung einer optisch aktiven N-substituierten Azetidin-2-carbonsäure-Verbindung

Info

Publication number
DE69933172D1
DE69933172D1 DE69933172T DE69933172T DE69933172D1 DE 69933172 D1 DE69933172 D1 DE 69933172D1 DE 69933172 T DE69933172 T DE 69933172T DE 69933172 T DE69933172 T DE 69933172T DE 69933172 D1 DE69933172 D1 DE 69933172D1
Authority
DE
Germany
Prior art keywords
producing
carboxylic acid
optically active
acid compound
substituted azetidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69933172T
Other languages
English (en)
Other versions
DE69933172T2 (de
Inventor
Yoshiki Takashima
Junko Kudo
Motoo Hazama
Amumu Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of DE69933172D1 publication Critical patent/DE69933172D1/de
Publication of DE69933172T2 publication Critical patent/DE69933172T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69933172T 1998-07-17 1999-07-15 Verfahren zur Herstellung einer optisch aktiven N-substituierten Azetidin-2-carbonsäure-Verbindung Expired - Lifetime DE69933172T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20336298A JP3757629B2 (ja) 1998-07-17 1998-07-17 光学活性ｎ−置換アゼチジン−２−カルボン酸化合物の製造方法
JP20336298 1998-07-17

Publications (2)

Publication Number Publication Date
DE69933172D1 true DE69933172D1 (de) 2006-10-26
DE69933172T2 DE69933172T2 (de) 2007-09-13

Family

ID=16472781

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69933172T Expired - Lifetime DE69933172T2 (de) 1998-07-17 1999-07-15 Verfahren zur Herstellung einer optisch aktiven N-substituierten Azetidin-2-carbonsäure-Verbindung

Country Status (4)

Country Link
US (1) US6143554A (de)
EP (1) EP0974670B1 (de)
JP (1) JP3757629B2 (de)
DE (1) DE69933172T2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69834276T2 (de) * 1997-01-24 2007-04-12 Sumitomo Chemical Co. Ltd. Verfahren zur Verbesserung der optischen Reinheit von Azetidin-2-carbonsäure
JP2000344739A (ja) 1999-06-01 2000-12-12 Sumitomo Chem Co Ltd Ｎ−保護−アゼチジン−２−カルボン酸の製造方法
EP1057894B1 (de) * 1999-06-04 2010-04-28 Sumitomo Chemical Company, Limited Esterase Gene und Verwendungen davon
DE60103959T2 (de) 2000-04-19 2005-07-07 Kaneka Corp. Neue azetidin-derivate und ein verfahren zur herstellung derselben
EP1536017B1 (de) 2003-10-30 2007-04-18 Sumitomo Chemical Company, Limited Verfahren zur Herstellung einer optisch aktiven Octahydro-1H-Indol-2-Carbonsäure
JP2006061112A (ja) * 2004-08-30 2006-03-09 Sumitomo Chemical Co Ltd 光学活性な２−（シクロペンチルメチル）−マロン酸モノエステルの製造方法
JP5825086B2 (ja) * 2011-12-19 2015-12-02 住友化学株式会社 α−置換−β−アミノ酸エステル誘導体不斉加水分解酵素

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4455372A (en) * 1981-10-06 1984-06-19 Tanabe Seiyaku Co., Ltd. Method for fermentative production of L-proline
EP0197474B1 (de) * 1985-04-01 1991-07-10 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Verfahren zur Herstellung von optisch aktiver Indolin-2-carbonsäure
EP0497103B1 (de) * 1991-01-10 1998-04-08 Sumitomo Chemical Company Limited Eine asymmetrisch aktive Esterase kodierendes Gen
TW397866B (en) * 1993-07-14 2000-07-11 Bristol Myers Squibb Co Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
JP3875283B2 (ja) * 1993-12-15 2007-01-31 住友化学株式会社 エステラーゼ遺伝子
IN187238B (de) * 1995-06-30 2002-03-09 Astra Ab
GB9614856D0 (en) * 1996-07-15 1996-09-04 Chiroscience Ltd New resolution method
DE69722538T2 (de) * 1996-09-06 2004-04-29 Sumitomo Chemical Co., Ltd. Verfahren zur Herstellung von optisch aktiver Azetidin-2-Carbonsäure
DE69834276T2 (de) * 1997-01-24 2007-04-12 Sumitomo Chemical Co. Ltd. Verfahren zur Verbesserung der optischen Reinheit von Azetidin-2-carbonsäure

Also Published As

Publication number Publication date
DE69933172T2 (de) 2007-09-13
JP2000032994A (ja) 2000-02-02
EP0974670B1 (de) 2006-09-13
EP0974670A3 (de) 2001-11-07
EP0974670A2 (de) 2000-01-26
JP3757629B2 (ja) 2006-03-22
US6143554A (en) 2000-11-07

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