DE69932281D1 - Antimikrobiell wirkendes Peptid - Google Patents

Antimikrobiell wirkendes Peptid

Info

Publication number
DE69932281D1
DE69932281D1 DE69932281T DE69932281T DE69932281D1 DE 69932281 D1 DE69932281 D1 DE 69932281D1 DE 69932281 T DE69932281 T DE 69932281T DE 69932281 T DE69932281 T DE 69932281T DE 69932281 D1 DE69932281 D1 DE 69932281D1
Authority
DE
Germany
Prior art keywords
amino acid
peptide
acid residue
arg ile
xaa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69932281T
Other languages
English (en)
Other versions
DE69932281T2 (de
Inventor
Michimasa Hirata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Publication of DE69932281D1 publication Critical patent/DE69932281D1/de
Application granted granted Critical
Publication of DE69932281T2 publication Critical patent/DE69932281T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S210/00—Liquid purification or separation
    • Y10S210/902—Materials removed
    • Y10S210/908—Organic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
DE69932281T 1998-03-25 1999-03-24 Antimikrobiell wirkendes Peptid Expired - Lifetime DE69932281T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP7813698 1998-03-25
JP7813698 1998-03-25
JP17646698A JP4037525B2 (ja) 1998-03-25 1998-06-23 新規抗菌性ペプチド
JP17646698 1998-06-23

Publications (2)

Publication Number Publication Date
DE69932281D1 true DE69932281D1 (de) 2006-08-24
DE69932281T2 DE69932281T2 (de) 2007-07-12

Family

ID=26419213

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69932281T Expired - Lifetime DE69932281T2 (de) 1998-03-25 1999-03-24 Antimikrobiell wirkendes Peptid

Country Status (6)

Country Link
US (1) US6040291A (de)
EP (1) EP0955312B1 (de)
JP (1) JP4037525B2 (de)
AT (1) ATE332922T1 (de)
CA (1) CA2264258C (de)
DE (1) DE69932281T2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2397835A1 (en) * 2000-01-20 2001-07-26 Regents Of The University Of Minnesota Polypeptides with therapeutic activity and methods of use
KR100442527B1 (ko) * 2001-02-22 2004-07-30 (주)펩티팜 항암 및 항생활성을 갖는 신규 폴리펩티드와 그를함유하는 항암제 및 항생제 조성물
KR100441402B1 (ko) * 2002-03-26 2004-07-23 한국과학기술원 항균 활성을 갖는 펩타이드, 이들의 유도체 및 이들을포함하는 항균 조성물
EP1380290A1 (de) 2002-07-09 2004-01-14 Universitair Medisch Centrum Utrecht Cross-Beta-Strukturweg und seine therapeutische Relevanz
US20050249724A1 (en) * 2002-07-11 2005-11-10 Upfront Chromatography A/S Extracorporeal stablised expanded bed adsorption method for the treatment of sepsis
US20060057134A1 (en) * 2002-07-22 2006-03-16 Teruo Kirikae Antibody against antibacterial peptide and utiliazation thereof
JP4471968B2 (ja) * 2003-01-28 2010-06-02 アカデミス ツィーケンホイス ライデン 毒素に対するｌｌ−３７由来のペプチド性阻害剤
US20060275303A1 (en) * 2003-02-27 2006-12-07 Robert Bals Modulating angiogenesis using LL-37/HCAP-18
WO2004098536A2 (en) * 2003-03-06 2004-11-18 The Regents Of The University Of California Anti-viral activity of cathelicidin peptides
US7173007B1 (en) 2003-04-02 2007-02-06 The Regents Of The University Of California Therapy for microbial infections
US7776823B2 (en) * 2003-10-21 2010-08-17 The Regents Of The University Of California Human cathelicidin antimicrobial peptides
US7718618B2 (en) * 2003-10-21 2010-05-18 The Regents Of The University Of California Human cathelicidin antimicrobial peptides
US20050282755A1 (en) * 2004-03-18 2005-12-22 Ansata Therapeutics, Inc. Compositions having antimicrobial activity and uses thereof
US7452856B2 (en) * 2004-07-06 2008-11-18 Seikagaku Corporation Antibacterial peptide
EP1621205A1 (de) * 2004-07-28 2006-02-01 OctoPlus Technologies B.V. CAP18 ähnliche Peptide mit antibiotischer Wirkung
ATE554394T1 (de) 2005-07-13 2012-05-15 Crossbeta Biosciences Bv Cross-beta-struktur-bindende verbindungen
US8114832B2 (en) 2005-07-13 2012-02-14 Crossbeta Biosciences B.V. Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition
US7799347B2 (en) * 2006-09-07 2010-09-21 Chondrex Inc. Endotoxin-adsorbent for the prevention and treatment of autoimmune diseases
WO2008073174A2 (en) * 2006-09-08 2008-06-19 The Regents Of The University Of California Antimicrobial therapy
US20090318534A1 (en) * 2006-09-27 2009-12-24 The Regents Of The University Of California Methods and compositions for the treatment of skin diseases and disorders
US20100166708A1 (en) * 2007-02-20 2010-07-01 The Regents Of The University Of California Antimicrobial and anti-inflammatory therapies and compositions
JP5354206B2 (ja) * 2007-02-26 2013-11-27 国立大学法人 奈良先端科学技術大学院大学 抗菌性ペプチド
US20100150985A1 (en) * 2008-04-24 2010-06-17 George Just Dental Implant, Endodontic Instrument, and Dental Filling Material Coated with a Peptide-Based Antimicrobial and Methods of Using and Making the Same
KR101303299B1 (ko) * 2010-10-08 2013-09-03 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 항균 펩타이드의 피부 세포 재생 촉진제로서의 신규한 용도
CN102766196B (zh) * 2011-05-06 2014-10-29 上海医药工业研究院 一组阳离子抗菌肽及其制备方法和应用
WO2017098474A1 (en) * 2015-12-09 2017-06-15 Universidade Do Minho Antimicrobial peptide-loaded hyaluronic acid-based formulations, method of production and uses thereof
CN112110984B (zh) * 2020-09-27 2022-06-14 深圳瑞德林生物技术有限公司 多肽的制备方法
CN113999285B (zh) * 2021-12-02 2023-02-14 浙江大学 抗菌七肽及其应用
CN114181293B (zh) * 2021-12-06 2023-09-22 郑州大学 一种人源抗菌肽ll-37改造体及其应用
CN115010791B (zh) * 2022-04-28 2024-03-08 南方海洋科学与工程广东省实验室(广州) 一种抗菌肽gw18及其应用
CN116874564B (zh) * 2023-08-24 2024-01-26 东北农业大学 人源广谱抗菌肽及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5489676A (en) * 1990-03-30 1996-02-06 Elsbach; Peter Polypeptides that potentiate bactericidal/permeability-increasing protein and methods for treating bacterial infections
US5618675A (en) * 1992-07-16 1997-04-08 Panorama Research, Inc. Methods and compositions for detecting lipopolysaccharides using CAP18 fragments
WO1994002589A1 (en) * 1992-07-17 1994-02-03 Panorama Research, Inc. Mammalian cationic proteins having lipopolysaccharide binding and anti-coagulant activity
AU7175694A (en) * 1993-06-17 1995-01-17 Xoma Corporation Lipopolysaccharide binding protein derivatives
US5804553A (en) * 1994-04-05 1998-09-08 University Of California Prophenins - antibiotic peptides

Also Published As

Publication number Publication date
JP4037525B2 (ja) 2008-01-23
EP0955312B1 (de) 2006-07-12
EP0955312A3 (de) 2002-03-20
CA2264258A1 (en) 1999-09-25
EP0955312A2 (de) 1999-11-10
ATE332922T1 (de) 2006-08-15
JPH11335396A (ja) 1999-12-07
CA2264258C (en) 2011-05-24
DE69932281T2 (de) 2007-07-12
US6040291A (en) 2000-03-21

Similar Documents

Publication Publication Date Title
ATE332922T1 (de) Antimikrobiell wirkendes peptid
AU1633200A (en) Human parathyroid hormone modifications, preparation and use
ES2192620T3 (es) Polipeptido receptor de il-13.
AUPP051497A0 (en) Antimicrobial peptides
WO1994007523A1 (en) Antimicrobial peptides
PL312989A1 (en) Therapeutic derivatives of peptides
EP0528312A3 (de) Zyklische Peptide und ihre Verwendung
AU4753297A (en) Peptide compositions with growth factor-like activity
AU4363199A (en) Use of hmg proteins for the preparation of medicaments having cytotoxic activity
CA2453112A1 (en) New cationic peptides of the dermaseptin family isolated from the skin secretion of phyllomedusa hypochondrialls
GB9606040D0 (en) Active peptide
WO2002000882A3 (en) Transport peptides dirived from erns protein, cytotoxic rnase of ribosome-inactivating protein or a rsv g-protein and analogues thereof
EP1887015A3 (de) Verfahren zur Gewinnung und Anwendung neuer humaner Defensine als biologisch aktive Eiweißstoffe zur Behandlung von Infektionen und anderen Erkrankungen
CA2306441A1 (fr) Peptides issus de gene env du virus de l'immunodeficience feline et leurs applications
DE60003860D1 (de) Peptide, die anti-Zellanhaftungsaktivität aufweisen
EP1557466A4 (de) Tumorantigenprotein und dessen verwendung
EP0837074A3 (de) Biologisch aktives Fibronektin-Fragment als Krebsmetastasehemmstoff
NZ508812A (en) Peptides for the prevention or treatment of HIV
AU2001278884A1 (en) Anti-hiv and anti-tumor peptides and fragments of lysozyme
BR9707067A (pt) Construção peptìdica, ácida nucleico recombinante, composição, utilização da mesma, e, de ácido nucleico.
NZ509284A (en) Tumour antigen peptide derived from SART-that binds to HLA-A24 antigen thereby facilitating recognition by a T call
WO1999060117A3 (fr) Polypeptide prax-1
EP1295943A4 (de) Polypeptide mit aktivität der stimulierung von neutrophilen
WO2022136442A3 (en) Compositions comprising cyclotides and other insecticidal peptides and uses thereof
WO2003048187A3 (en) Peptides and use thereof in therapeutic agents against hiv infection

Legal Events

Date Code Title Description
8364 No opposition during term of opposition