DE69930872T8 - Antikörper gegen verkürzten vegf-d und deren verwendungen - Google Patents
Antikörper gegen verkürzten vegf-d und deren verwendungen Download PDFInfo
- Publication number
- DE69930872T8 DE69930872T8 DE69930872T DE69930872T DE69930872T8 DE 69930872 T8 DE69930872 T8 DE 69930872T8 DE 69930872 T DE69930872 T DE 69930872T DE 69930872 T DE69930872 T DE 69930872T DE 69930872 T8 DE69930872 T8 DE 69930872T8
- Authority
- DE
- Germany
- Prior art keywords
- vegf
- shortened
- antibodies against
- antibodies
- vegfr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
- Y10S530/809—Fused cells, e.g. hybridoma
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11325498P | 1998-12-21 | 1998-12-21 | |
US113254P | 1998-12-21 | ||
US13455699P | 1999-05-17 | 1999-05-17 | |
US134556P | 1999-05-17 | ||
PCT/US1999/031332 WO2000037025A2 (en) | 1998-12-21 | 1999-12-21 | Antibodies to truncated vegf-d and uses thereof |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69930872D1 DE69930872D1 (de) | 2006-05-24 |
DE69930872T2 DE69930872T2 (de) | 2006-11-30 |
DE69930872T8 true DE69930872T8 (de) | 2007-05-03 |
Family
ID=26810852
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69930872T Active DE69930872T8 (de) | 1998-12-21 | 1999-12-21 | Antikörper gegen verkürzten vegf-d und deren verwendungen |
Country Status (13)
Country | Link |
---|---|
US (3) | US6383484B1 (de) |
EP (1) | EP1140175B1 (de) |
JP (1) | JP4632543B2 (de) |
KR (1) | KR20010081089A (de) |
CN (1) | CN1330555A (de) |
AT (1) | ATE322909T1 (de) |
AU (2) | AU770332B2 (de) |
CA (1) | CA2355896A1 (de) |
DE (1) | DE69930872T8 (de) |
DK (1) | DK1140175T3 (de) |
ES (1) | ES2259247T3 (de) |
PT (1) | PT1140175E (de) |
WO (1) | WO2000037025A2 (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6824777B1 (en) | 1992-10-09 | 2004-11-30 | Licentia Ltd. | Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy |
AU7142996A (en) * | 1995-09-29 | 1997-04-28 | Universita' Degli Studi Di Siena | Regulated genes and uses thereof |
EP0956339B1 (de) | 1996-08-23 | 2005-10-12 | Ludwig Institute For Cancer Research | Rekombinanter vaskulärer endothelzellen wachstumsfaktor d (vegf-d) |
US7125714B2 (en) | 1997-02-05 | 2006-10-24 | Licentia Ltd. | Progenitor cell materials and methods |
US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO2000058511A1 (en) * | 1999-03-26 | 2000-10-05 | Ludwig Institute For Cancer Research | Screening and therapy for lymphatic disorders involving the flt4 receptor tyrosine kinase (vegfr-3) |
US7045133B2 (en) * | 2000-01-18 | 2006-05-16 | Ludwig Institute For Cancer Research | VEGF-D/VEGF-C/VEGF peptidomimetic inhibitor |
JP4981229B2 (ja) * | 2000-02-25 | 2012-07-18 | ルードヴィッヒ インスティテュート フォー キャンサー リサーチ | ハイブリッド血管内皮成長因子DNAsおよびタンパク質に関与する物質および方法 |
ES2234818T3 (es) * | 2000-03-02 | 2005-07-01 | Ludwig Institute For Cancer Research | Procedimiento para tratar canceres que expresan el factor de crecimiento endotelial d. |
US20020102260A1 (en) | 2000-03-02 | 2002-08-01 | Marc Achen | Methods for treating neoplastic disease characterized by vascular endothelial growth factor D expression, for screening for neoplastic disease or metastatic risk, and for maintaining vascularization of tissue |
JP2004511430A (ja) * | 2000-05-24 | 2004-04-15 | イムクローン システムズ インコーポレイティド | 二重特異性免疫グロブリン様抗原結合蛋白および製造方法 |
US7611711B2 (en) * | 2001-01-17 | 2009-11-03 | Vegenics Limited | VEGFR-3 inhibitor materials and methods |
CN1494552A (zh) | 2001-01-19 | 2004-05-05 | ·��ά��֢�о�Ժ | Flt4(VEGFR-3)作为靶用于肿瘤成像和抗肿瘤治疗 |
US20020164624A1 (en) * | 2001-02-12 | 2002-11-07 | Waldemar Debinski | VEGF-D expression in brain cancer |
US20050232921A1 (en) * | 2001-04-13 | 2005-10-20 | Rosen Craig A | Vascular endothelial growth factor 2 |
JP2004536579A (ja) | 2001-04-13 | 2004-12-09 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 血管内皮増殖因子2 |
US7595378B2 (en) | 2001-06-13 | 2009-09-29 | Genmab A/S | Human monoclonal antibodies to epidermal growth factor receptor (EGFR) |
CA2450285C (en) * | 2001-06-13 | 2016-08-02 | Genmab A/S | Human monoclonal antibodies to epidermal growth factor receptor (egfr) |
EP1411983A4 (de) * | 2001-06-26 | 2006-06-21 | Imclone Systems Inc | Bispezifische antikörper, die an vegf-rezeptoren binden |
AU2002322461B2 (en) * | 2001-07-12 | 2007-12-06 | Vegenics Limited | Lymphatic endothelial cells materials and methods |
US20040214766A1 (en) * | 2001-10-01 | 2004-10-28 | Kari Alitalo | VEGF-C or VEGF-D materials and methods for treatment of neuropathologies |
US20030113324A1 (en) * | 2001-10-01 | 2003-06-19 | Kari Alitalo | Neuropilin/VEGF-C/VEGFR-3 materials and methods |
CA2493572A1 (en) * | 2002-07-23 | 2004-01-29 | Ludwig Institute For Cancer Research | Methods and compositions for activating or inhibiting vegf-d and vegf-c |
US7608684B2 (en) * | 2002-11-12 | 2009-10-27 | Mochida Pharmaceuticals Co., Ltd. | Soluble CD14 antigen |
ATE460430T1 (de) | 2002-11-12 | 2010-03-15 | Mochida Pharm Co Ltd | Kit zur untersuchung von menschlichem niedermolekulargewicht cd14 und antikörper |
DE10256410B3 (de) * | 2002-12-02 | 2004-03-11 | Daimlerchrysler Ag | Verfahren zum Energiemanagement von Klimaanlagen |
US20040120950A1 (en) * | 2002-12-20 | 2004-06-24 | Kari Alitalo | Modulation of VEGF-C/VEGFR-3 interactions in the treatment of rheumatoid arthritis |
US20040248796A1 (en) * | 2003-02-04 | 2004-12-09 | Kari Alitalo | VEGF-B and PDGF modulation of stem cells |
US20050043235A1 (en) * | 2003-06-12 | 2005-02-24 | Kari Alitalo | Use of VEGF-C or VEGF-D in reconstructive surgery |
WO2005016963A2 (en) * | 2003-06-12 | 2005-02-24 | Ludwig Institute For Cancer Research | Heparin binding veger-3 ligands |
KR101471732B1 (ko) | 2003-08-27 | 2014-12-16 | 옵쏘테크 코포레이션 | 안구의 혈관신생성 장애를 치료하기 위한 조합 치료법 |
WO2005087812A1 (en) * | 2004-03-05 | 2005-09-22 | Ludwig Institute For Cancer Research | Multivalent antibody materials and methods for vegf/pdgf family of growth factors |
US20060024302A1 (en) * | 2004-03-05 | 2006-02-02 | Ludwig Institute For Cancer Research | Chimeric anti-VEGF-D antibodies and humanized anti-VEGF-D antibodies and methods of using same |
US7595149B1 (en) | 2004-11-08 | 2009-09-29 | University Of Kentucky Research Foundation | Methods for cancer detection |
ES2350269T3 (es) * | 2006-01-18 | 2011-01-20 | The General Hospital Corporation | Métodos de aumento de la función linfática. |
US7667880B2 (en) * | 2006-02-10 | 2010-02-23 | Adobe Systems, Incorporated | Method and apparatus for previewing digital motion picture content |
US9073997B2 (en) * | 2007-02-02 | 2015-07-07 | Vegenics Pty Limited | Growth factor antagonists for organ transplant alloimmunity and arteriosclerosis |
AR066660A1 (es) * | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
DE102007038730A1 (de) * | 2007-08-16 | 2009-02-19 | Carl Zeiss Meditec Ag | Nachweis des menschlichen Vascular Endothelial Growth Factor |
CN101245106B (zh) * | 2007-12-04 | 2011-07-20 | 澳赛尔斯生物技术(上海)有限公司 | 抗vegf受体单克隆抗体及其制备方法和应用 |
US7811776B2 (en) | 2007-12-05 | 2010-10-12 | University Of Cincinnati | Use of VEGF-D in the diagnosis of lymphangioleiomyomatosis (LAM) disease |
WO2009143584A1 (en) * | 2008-05-30 | 2009-12-03 | Vegenics Limited | Treatment of pulmonary edema |
CN102076844B (zh) | 2008-06-30 | 2013-08-07 | 成血管细胞系统公司 | 采用组合疗法的眼病和过度血管新生的治疗 |
US11298113B2 (en) | 2008-10-01 | 2022-04-12 | Covidien Lp | Device for needle biopsy with integrated needle protection |
US9186128B2 (en) | 2008-10-01 | 2015-11-17 | Covidien Lp | Needle biopsy device |
US8968210B2 (en) | 2008-10-01 | 2015-03-03 | Covidien LLP | Device for needle biopsy with integrated needle protection |
US9782565B2 (en) | 2008-10-01 | 2017-10-10 | Covidien Lp | Endoscopic ultrasound-guided biliary access system |
US9332973B2 (en) | 2008-10-01 | 2016-05-10 | Covidien Lp | Needle biopsy device with exchangeable needle and integrated needle protection |
EP2393832B1 (de) * | 2009-02-06 | 2015-07-08 | Pepscan Systems BV | Verkürzte cystin-knoten-proteine |
HRP20221259T1 (hr) | 2009-02-13 | 2022-12-09 | Immunomedics, Inc. | Imunokonjugati s intracelularnom vezom koja se može rascijepiti |
AU2010230855A1 (en) * | 2009-04-03 | 2012-01-12 | Vegenics Limited | Anti-VEGF-D antibodies |
IN2012DN01663A (de) | 2009-09-16 | 2015-06-05 | Immunomedics Inc | |
ES2978177T3 (es) | 2009-12-02 | 2024-09-06 | Immunomedics Inc | Combinación de radio inmunoterapia y conjugados anticuerpo-fármaco para mejorar la terapia contra el cáncer |
WO2011106697A1 (en) | 2010-02-25 | 2011-09-01 | Schepens Eye Research Institute | Therapeutic compositions for the treatment of dry eye disease |
CA2831572C (en) | 2011-05-02 | 2019-11-26 | Immunomedics, Inc. | Ultrafiltration concentration of allotype selected antibodies for small-volume administration |
US9315567B2 (en) | 2012-08-14 | 2016-04-19 | Ibc Pharmaceuticals, Inc. | T-cell redirecting bispecific antibodies for treatment of disease |
HUE057977T2 (hu) | 2012-12-13 | 2022-06-28 | Immunomedics Inc | Ellenanyagok és SN-38 immunkonjugátumainak dózisai javított hatásossággal és csökkentett toxicitással |
RS60026B1 (sr) | 2013-02-18 | 2020-04-30 | Vegenics Pty Ltd | Molekuli koji vezuju ligande i njihove upotrebe |
CA3107182A1 (en) | 2013-07-12 | 2015-01-15 | Iveric Bio, Inc. | Methods for treating or preventing ophthalmological conditions |
CA2937236C (en) | 2014-02-21 | 2023-03-07 | Ibc Pharmaceuticals, Inc. | Disease therapy by inducing immune response to trop-2 expressing cells |
EP3110445A4 (de) | 2014-02-25 | 2017-09-27 | Immunomedics, Inc. | Humanisierter rfb4-anti-cd22-antikörper |
WO2015200260A1 (en) | 2014-06-24 | 2015-12-30 | Immunomedics, Inc. | Anti-histone therapy for vascular necrosis in severe glomerulonephritis |
PL3204018T3 (pl) | 2014-10-07 | 2022-01-03 | Immunomedics, Inc. | Neoadiuwantowe zastosowanie koniugatów przeciwciało-lek |
CA2981543A1 (en) | 2015-04-22 | 2016-10-27 | Immunomedics, Inc. | Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells |
PL3313443T3 (pl) | 2015-06-25 | 2023-11-06 | Immunomedics, Inc. | Łączenie przeciwciał anty-hla-dr lub anty-trop-2 z inhibitorami mikrotubuli, inhibitorami parp, 5 inhibitorami kinazy brutona lub inhibitorami 3-kinazy fosfoinozytydu istotnie poprawia wynik terapeutyczny nowotworu |
SI3316885T1 (sl) | 2015-07-01 | 2021-09-30 | Immunomedics, Inc. | Imunokonjugati protitelo-SN-38 z linkerjem CL2A |
CN109072241A (zh) | 2016-02-08 | 2018-12-21 | 维特里萨医疗公司 | 具有改善的玻璃体内半衰期的组合物及其用途 |
CN108794629A (zh) * | 2018-06-28 | 2018-11-13 | 浙江众意生物科技有限公司 | 一种vegf-d单克隆抗体及试剂盒 |
WO2022239720A1 (ja) | 2021-05-10 | 2022-11-17 | 公益財団法人川崎市産業振興財団 | 抗原への結合親和性を低減させた抗体 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998033917A1 (en) * | 1994-11-14 | 1998-08-06 | The Ludwig Institute For Cancer Research | Vascular endothelial growth factor c (vegf-c) protein and gene, mutants thereof, and uses thereof |
EP0935001B2 (de) * | 1996-07-15 | 2011-08-10 | Chugai Seiyaku Kabushiki Kaisha | Neuartige vegf-ähnliche faktoren |
EP0956339B1 (de) * | 1996-08-23 | 2005-10-12 | Ludwig Institute For Cancer Research | Rekombinanter vaskulärer endothelzellen wachstumsfaktor d (vegf-d) |
AU5439998A (en) * | 1996-12-06 | 1998-06-29 | Zymogenetics Inc. | Vascular endothelial growth factor |
EP1054687B8 (de) * | 1997-12-24 | 2008-07-16 | Vegenics Limited | Expressionsvektoren und zellinien zur expression von vaskulärem wachstumsfaktor d, sowie verfahren zur behandlung von melanomen |
EP1185559A2 (de) * | 1999-04-28 | 2002-03-13 | Board Of Regents, The University Of Texas System | Zusammensetzungen und verfahren zur krebsbehandlung durch die selektive hemmung von vegf |
-
1999
- 1999-12-21 DK DK99969995T patent/DK1140175T3/da active
- 1999-12-21 ES ES99969995T patent/ES2259247T3/es not_active Expired - Lifetime
- 1999-12-21 DE DE69930872T patent/DE69930872T8/de active Active
- 1999-12-21 WO PCT/US1999/031332 patent/WO2000037025A2/en not_active Application Discontinuation
- 1999-12-21 EP EP99969995A patent/EP1140175B1/de not_active Expired - Lifetime
- 1999-12-21 PT PT99969995T patent/PT1140175E/pt unknown
- 1999-12-21 CN CN99814571A patent/CN1330555A/zh active Pending
- 1999-12-21 KR KR1020017007826A patent/KR20010081089A/ko not_active Application Discontinuation
- 1999-12-21 CA CA002355896A patent/CA2355896A1/en not_active Abandoned
- 1999-12-21 AT AT99969995T patent/ATE322909T1/de not_active IP Right Cessation
- 1999-12-21 JP JP2000589139A patent/JP4632543B2/ja not_active Expired - Fee Related
- 1999-12-21 US US09/469,186 patent/US6383484B1/en not_active Expired - Lifetime
- 1999-12-21 AU AU33432/00A patent/AU770332B2/en not_active Ceased
-
2002
- 2002-03-19 US US10/100,037 patent/US6730489B1/en not_active Expired - Fee Related
-
2004
- 2004-02-18 US US10/779,731 patent/US7097986B2/en not_active Expired - Fee Related
- 2004-05-17 AU AU2004202080A patent/AU2004202080A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2002532113A (ja) | 2002-10-02 |
WO2000037025A3 (en) | 2000-11-16 |
CA2355896A1 (en) | 2000-06-29 |
US20040141917A1 (en) | 2004-07-22 |
AU3343200A (en) | 2000-07-12 |
WO2000037025A2 (en) | 2000-06-29 |
DK1140175T3 (da) | 2006-08-14 |
AU770332B2 (en) | 2004-02-19 |
US6730489B1 (en) | 2004-05-04 |
EP1140175A2 (de) | 2001-10-10 |
US6383484B1 (en) | 2002-05-07 |
EP1140175A4 (de) | 2003-03-05 |
JP4632543B2 (ja) | 2011-02-16 |
PT1140175E (pt) | 2006-06-30 |
US7097986B2 (en) | 2006-08-29 |
DE69930872T2 (de) | 2006-11-30 |
EP1140175B1 (de) | 2006-04-12 |
ATE322909T1 (de) | 2006-04-15 |
ES2259247T3 (es) | 2006-09-16 |
AU2004202080A1 (en) | 2004-06-10 |
KR20010081089A (ko) | 2001-08-25 |
CN1330555A (zh) | 2002-01-09 |
DE69930872D1 (de) | 2006-05-24 |
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