DE69930401D1 - Vorrichtung zur abgabe von fentanyl und sufentanil - Google Patents

Vorrichtung zur abgabe von fentanyl und sufentanil

Info

Publication number
DE69930401D1
DE69930401D1 DE69930401T DE69930401T DE69930401D1 DE 69930401 D1 DE69930401 D1 DE 69930401D1 DE 69930401 T DE69930401 T DE 69930401T DE 69930401 T DE69930401 T DE 69930401T DE 69930401 D1 DE69930401 D1 DE 69930401D1
Authority
DE
Germany
Prior art keywords
delivery systems
sufentanil
heat
transdermal analgesic
analgesic delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69930401T
Other languages
English (en)
Other versions
DE69930401T2 (de
Inventor
Jie Zhang
Hao Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zars Inc
Original Assignee
Zars Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zars Inc filed Critical Zars Inc
Publication of DE69930401D1 publication Critical patent/DE69930401D1/de
Application granted granted Critical
Publication of DE69930401T2 publication Critical patent/DE69930401T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/00187—Wound bandages insulating; warmth or cold applying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/00187—Wound bandages insulating; warmth or cold applying
    • A61F2013/00204—Wound bandages insulating; warmth or cold applying insulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00902—Plasters containing means
    • A61F2013/00906—Plasters containing means for transcutaneous or transdermal drugs application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00902—Plasters containing means
    • A61F2013/0091—Plasters containing means with disinfecting or anaesthetics means, e.g. anti-mycrobic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
    • A61F7/032—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction using oxygen from the air, e.g. pocket-stoves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
    • A61F7/032—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction using oxygen from the air, e.g. pocket-stoves
    • A61F7/034—Flameless
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Thermal Sciences (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69930401T 1998-09-29 1999-09-15 Vorrichtung zur abgabe von fentanyl und sufentanil Expired - Fee Related DE69930401T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/162,587 US6284266B1 (en) 1995-07-28 1998-09-29 Methods and apparatus for improved administration of fentanyl and sufentanil
PCT/US1999/021140 WO2000018338A1 (en) 1998-09-29 1999-09-15 Methods and apparatus for improved administration of fentanyl and sufentanil
US162587 2005-09-15

Publications (2)

Publication Number Publication Date
DE69930401D1 true DE69930401D1 (de) 2006-05-11
DE69930401T2 DE69930401T2 (de) 2006-11-16

Family

ID=22586280

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69930401T Expired - Fee Related DE69930401T2 (de) 1998-09-29 1999-09-15 Vorrichtung zur abgabe von fentanyl und sufentanil

Country Status (11)

Country Link
US (1) US6284266B1 (de)
EP (1) EP1117356B1 (de)
JP (1) JP2002525297A (de)
CN (1) CN100402001C (de)
AT (1) ATE320233T1 (de)
AU (1) AU5924199A (de)
CA (1) CA2345494C (de)
DE (1) DE69930401T2 (de)
ES (1) ES2260936T3 (de)
HK (1) HK1040047A1 (de)
WO (1) WO2000018338A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245347B1 (en) * 1995-07-28 2001-06-12 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
US20020114827A1 (en) * 1995-07-28 2002-08-22 Jie Zhang Methods and apparatus for improved administration of analgesics
US20040265353A1 (en) * 1995-07-28 2004-12-30 Zars, Inc. Systems and methods for treating panic attacks
US6756053B2 (en) * 1995-07-28 2004-06-29 Zars, Inc. Controlled heat induced rapid delivery of pharmaceuticals from skin depot
WO2001064149A1 (en) * 2000-02-29 2001-09-07 Jie Zhang Improved transdermal drug patch
US20020106407A1 (en) * 2000-12-11 2002-08-08 Dennis Coleman Method and apparatus for treating breakthrough pain
DE10102817B4 (de) * 2001-01-23 2006-01-12 Lts Lohmann Therapie-Systeme Ag Vorrichtung und Verfahren zur Hitzepulsgestützten transdermalen Applikation von Wirkstoffen
US6893453B2 (en) * 2002-12-17 2005-05-17 Kimberly-Clark Worldwide, Inc. Thermal therapy pad with variable heat control
US8524272B2 (en) 2003-08-15 2013-09-03 Mylan Technologies, Inc. Transdermal patch incorporating active agent migration barrier layer
GB0412793D0 (en) * 2004-06-09 2004-07-14 Boots Healthcare Int Ltd Therapeutic product
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
US9004059B2 (en) * 2006-08-10 2015-04-14 Rechargeable Battery Corporation Reusable heater in a package
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
CN104069567A (zh) 2007-03-19 2014-10-01 茵苏莱恩医药有限公司 药物输送设备
WO2009081262A1 (en) 2007-12-18 2009-07-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
NZ579669A (en) * 2007-03-20 2013-05-31 Wyeth Llc Thermal device with insulative layer to dampen temperature changes in heat source
EP2240099B1 (de) 2008-01-04 2018-02-21 Edge Systems LLC Vorrichtung zur hautbehandlung
CA2743027C (en) 2008-11-07 2016-04-12 Insuline Medical Ltd. Device and method for drug delivery
JP4934163B2 (ja) * 2009-03-18 2012-05-16 オカモト株式会社 皮膚貼付積層体
WO2010114973A1 (en) * 2009-04-01 2010-10-07 Jie Zhang Methods for treating myofascial, muscle, and/or back pain
JP5648174B2 (ja) * 2009-05-04 2015-01-07 ヌボ リサーチ インコーポレイテッド 神経腫、神経絞扼、および他の状態と関連する疼痛を処置する方法
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia
EP3437575B1 (de) 2013-03-15 2021-04-21 Edge Systems LLC Vorrichtungen und systeme zur hautbehandlung
JP6711816B2 (ja) * 2014-08-06 2020-06-17 珠海漢盈科技有限公司Ｈａｎｄｙ Ｔｅｃｈｎｏｌｏｇｙ （Ｚｈｕｈａｉ） Ｌｔｄ． 自己発熱保温型フィルム並びにそれにより製造されたフェイスマスク及びアイシート
EP3237055B1 (de) 2014-12-23 2020-08-12 Edge Systems LLC Vorrichtungen und verfahren zur behandlung der haut unter verwendung eines rollerballs oder eines abführenden elements
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
US9650338B1 (en) 2016-07-29 2017-05-16 VDM Biochemicals, Inc. Opioid antagonist compounds and methods of making and using
JP2021518233A (ja) * 2018-03-28 2021-08-02 ニードルカルム・プロプライエタリー・リミテッド 疼痛管理のためのデバイスおよびシステム
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929131A (en) 1975-01-09 1975-12-30 Thomas L Hardwick Bandage and method of using same
DE2823174A1 (de) 1977-07-06 1979-01-25 Astra Laekemedel Ab Arzneimittel fuer die prophylaktische behandlung postoperativer tiefer venenthrombose
SE7713618L (sv) 1977-12-01 1979-06-02 Astra Laekemedel Ab Lokalanestetisk blandning
US4230105A (en) 1978-11-13 1980-10-28 Merck & Co., Inc. Transdermal delivery of drugs
US4286592A (en) 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US5651768A (en) 1983-08-18 1997-07-29 Drug Delivery Systems, Inc. Transdermal drug applicator and electrodes therefor
US5605536A (en) 1983-08-18 1997-02-25 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
JPS60174716A (ja) 1984-02-21 1985-09-09 Yamanouchi Pharmaceut Co Ltd パツチ剤
GB2163956B (en) 1984-09-08 1988-03-30 Ile De France Percutaneous anaesthetic composition for topical application
US4747841A (en) 1985-03-19 1988-05-31 Yasuro Kuratomi Methods and instruments of moxibustion
US4693706A (en) 1986-08-11 1987-09-15 Mark L. Anderson Two compartment mixing syringe
EP0258521B1 (de) 1986-08-23 1990-05-02 Arno Walter Latzke Mittel zur Applikation von transdermal resorbierbaren Wirkstoffen
US4911707A (en) 1987-02-13 1990-03-27 Ciba-Geigy Corporation Monolithic user-activated transdermal therapeutic system
GB8712518D0 (en) 1987-05-28 1987-07-01 Univ Belfast Unit-dose film composition
DK158336C (da) 1987-09-22 1990-10-01 Coloplast As Forbindsmateriale til behandling af saar samt smaalegemer til brug ved fremstilling deraf
US4830855A (en) 1987-11-13 1989-05-16 Landec Labs, Inc. Temperature-controlled active agent dispenser
JPH01122037U (de) 1988-02-12 1989-08-18
DE3806562A1 (de) 1988-03-01 1989-09-14 Alpha Therapeutic Gmbh Zweikammerspritze mit einer fuellung aus aktivitaetsempfindlichem humanen protein als wirkstoff
US4913957A (en) 1988-05-23 1990-04-03 Kimberly-Clark Corporation Thermal retaining fabric laminate
US5236714A (en) * 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
DE3903794A1 (de) 1989-02-09 1990-08-16 Lohmann Therapie Syst Lts Therapeutisches system zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung
US5217718A (en) 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5276032A (en) 1989-12-28 1994-01-04 King O Newton Vision aid and anesthetic composition
US5229133A (en) 1990-01-24 1993-07-20 Alza Corporation Delivery system comprising means for controlling internal pressure
US5279594A (en) 1990-05-23 1994-01-18 Jackson Richard R Intubation devices with local anesthetic effect for medical use
US5114411A (en) 1990-11-19 1992-05-19 Habley Medical Technology Corporation Multi-chamber vial
US5108710A (en) 1990-11-26 1992-04-28 Little Amy C Transdermal patch holder
US5580573A (en) 1991-02-01 1996-12-03 E. R. Squibb And Sons, Inc. Temperature activated controlled release
US5213129A (en) 1991-03-25 1993-05-25 Csb Limited Partnership Fluid mixing device
WO1993007842A1 (en) * 1991-10-15 1993-04-29 Cygnus Therapeutic Systems Thermal enhancement of transdermal drug administration
US5329976A (en) 1991-12-09 1994-07-19 Habley Medical Technology Corporation Syringe-filling and medication mixing dispenser
DK168420B1 (da) 1992-03-27 1994-03-28 Coloplast As Varmebandage
CN1092330A (zh) * 1993-03-18 1994-09-21 孙金森 医疗止痛热敷袋
US5330452A (en) 1993-06-01 1994-07-19 Zook Gerald P Topical medicating device
US5534021A (en) 1994-09-01 1996-07-09 Dvoretzky; Israel Heating pad for providing heat therapy
US5728058A (en) 1995-06-29 1998-03-17 The Procter & Gamble Company Elastic knee wrap
ATE212819T1 (de) 1995-06-29 2002-02-15 Procter & Gamble Wärmezellen
JP3685263B2 (ja) 1995-06-29 2005-08-17 ザ、プロクター、エンド、ギャンブル、カンパニー 位置保持手段を有する翼形状の熱ネックラップ
AU5956096A (en) 1995-06-29 1997-01-30 Procter & Gamble Company, The Elastic back wrap having diamond-shaped thermal pattern and anti-slip means
US5658583A (en) 1995-07-28 1997-08-19 Zhang; Jie Apparatus and methods for improved noninvasive dermal administration of pharmaceuticals
US5906830A (en) 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
AU7286996A (en) 1995-10-18 1997-05-07 Ciba-Geigy Ag Thermopile powered transdermal drug delivery device
US5626571A (en) 1995-11-30 1997-05-06 The Procter & Gamble Company Absorbent articles having soft, strong nonwoven component
US5984995A (en) 1996-03-29 1999-11-16 The Procter & Gamble Company Heat cells
AU3136897A (en) * 1996-05-22 1997-12-09 Diversified Pharmaceuticals, Inc. Compositions, methods and devices for the transdermal delivery of drugs
WO1997049361A1 (en) 1996-06-27 1997-12-31 The Procter & Gamble Company Thermal pad having a common attachment and oxygen permeable side
US5674270A (en) 1996-06-27 1997-10-07 The Procter & Gamble Company Thermal pad having a common attachment and oxygen permeable side
US5980562A (en) 1996-07-26 1999-11-09 The Procter & Gamble Company Elastic back wrap having diamond-shaped thermal pattern and anti-slip means
US5735889A (en) 1996-11-08 1998-04-07 The Procter & Gamble Company Thermal neck wrap having means for position maintenance
DE69737695T2 (de) 1996-12-23 2008-01-10 The Procter & Gamble Company, Cincinnati Lokal anwendbares adhäsiv für die haut und bequeme entfernung
PL334398A1 (en) 1996-12-31 2000-02-28 Procter & Gamble Disposable elastic thermal dorsum bandage and method of treating backache
PL334389A1 (en) 1996-12-31 2000-02-28 Procter & Gamble Thermal package containing a plurality of separate heating cells
US6048326A (en) 1996-12-31 2000-04-11 The Procter & Gamble Company Disposable elastic thermal knee wrap
US6019782A (en) 1996-12-31 2000-02-01 The Procter & Gamble Company Disposable thermal body pad
US5925072A (en) 1996-12-31 1999-07-20 The Procter & Gamble Company Disposable elastic thermal back wrap
US5860945A (en) 1996-12-31 1999-01-19 The Procter & Gamble Company Disposable elastic thermal knee wrap
JP2002512539A (ja) 1996-12-31 2002-04-23 ザ、プロクター、エンド、ギャンブル、カンパニー 使い捨て式温熱首包装体
US6020040A (en) 1996-12-31 2000-02-01 The Procter & Gamble Company Thermal pack having a plurality of individual heat cells
US6042673A (en) 1997-05-15 2000-03-28 The Procter & Gamble Company Method for making a flangeless seam for use in disposable articles
US5906637A (en) 1997-08-21 1999-05-25 The Procter & Gamble Company Disposable elastic thermal uniaxial joint wrap
US5904710A (en) 1997-08-21 1999-05-18 The Procter & Gamble Company Disposable elastic thermal body wrap
USD403779S (en) 1998-01-20 1999-01-05 The Procter & Gamble Company Knee wrap having thermal cells
USD409757S (en) 1998-01-20 1999-05-11 The Procter & Gamble Company Back wrap having thermal cells
USD407822S (en) 1998-01-20 1999-04-06 The Procter & Gamble Company Back wrap having thermal cells
USD403778S (en) 1998-01-20 1999-01-05 The Procter & Gamble Company Neck wrap having thermal cells
USD412751S (en) 1998-05-07 1999-08-10 The Procter & Gamble Company Back wrap having thermal cells
USD407824S (en) 1998-05-07 1999-04-06 The Procter & Gamble Company Neck wrap having thermal cells
USD417283S (en) 1998-05-07 1999-11-30 The Procter & Gamble Company Neck wrap having thermal cells
USD408923S (en) 1998-05-07 1999-04-27 The Procter & Gamble Company Neck wrap having thermal cells
USD418606S (en) 1998-05-07 2000-01-04 The Procter & Gamble Company Neck wrap having thermal cells

Also Published As

Publication number Publication date
ES2260936T3 (es) 2006-11-01
US6284266B1 (en) 2001-09-04
EP1117356A4 (de) 2002-07-24
HK1040047A1 (zh) 2002-05-24
AU5924199A (en) 2000-04-17
JP2002525297A (ja) 2002-08-13
DE69930401T2 (de) 2006-11-16
EP1117356A1 (de) 2001-07-25
EP1117356B1 (de) 2006-03-15
CN100402001C (zh) 2008-07-16
CN1331575A (zh) 2002-01-16
CA2345494C (en) 2007-08-21
ATE320233T1 (de) 2006-04-15
CA2345494A1 (en) 2000-04-06
WO2000018338A1 (en) 2000-04-06

Similar Documents

Publication Publication Date Title
ATE320233T1 (de) Vorrichtung zur abgabe von fentanyl und sufentanil
DK1284656T3 (da) Opretningsindretning til fremföring af en usymmetrisk indretning med en forudbestemt orientering
BR0311443A (pt) Método e dispositivo para controlar farmacocinética de droga
AU2003216321A1 (en) Tamper-resistant transdermal opioid delivery devices
GR960100179A (el) Συσκευη διαδερμικης χορηγησης των φεντανιλ και σουφεντανιλ με ηλεκτρομεταφορα.
AU6501201A (en) Systems and methods for monitoring health and delivering drugs transdermally
DE69506007T2 (de) Transdermales system zur gleichzeitigen verabreichung von mehreren wirkstoffen
WO2005107726A3 (en) Method for the treatment of back pain
ATE232735T1 (de) Vorrichtung zur gesteuerten anästhesie, analgesie und/oder sedierung
WO2003024383A3 (en) Methods and apparatus for improved administration of analgesics
ATE267004T1 (de) Vorrichtung zur arzneistoffabgabe, insbesondere zur verabreichung von progestinen und östrogenen
ATE442184T1 (de) Vorrichtung zur iontophoretischen, transdermalen verabreichung von fentanyl und sufentanil
MY137620A (en) Therapeutic treatment
SE9603725D0 (sv) New teatment
DE50108168D1 (de) Transdermales therapeutisches system zur abgabe von lerisetron
PL351922A1 (en) Use of saredutant and its pharmaceutically-permitted salts for making drugs usable in therapy or prevention of any mood disorders, adaptability disorders, or mixed drug-depressive disorders
ATE335496T1 (de) Angiotensin ii und analoga zur begrenzung von narben und adhäsionbildung
TR200003502T2 (tr) Bir Piperidin Maddesi P Antagonistini İçeren Mikroemülsiyon Prekonsantratları
DE69901805T2 (de) Pharmazeutische zusammensetzung mit mutiertem tyrosin 353 ezrin
HK1046847A1 (en) Pharmaceutical combination with analgesic action containing paracetamol and buspirone.
DE60028207D1 (de) Transdermales therapeutisches system zur verabreichung von calciumantagonisten
ATE228356T1 (de) Verfahren zur vermeidung des missbrauchs eines transdermalen therapeutischen systems
BR9801839A (pt) Medicamento analgésico e aplicação de (+) -0-demetiltramadol.
UA37510A (uk) Спосіб лікування загрози передчасного переривання вагітності
UA36251A (uk) Спосіб комплексної терапії простої шизофренії

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee