DE69930401D1 - Vorrichtung zur abgabe von fentanyl und sufentanil - Google Patents

Vorrichtung zur abgabe von fentanyl und sufentanil

Info

Publication number
DE69930401D1
DE69930401D1 DE69930401T DE69930401T DE69930401D1 DE 69930401 D1 DE69930401 D1 DE 69930401D1 DE 69930401 T DE69930401 T DE 69930401T DE 69930401 T DE69930401 T DE 69930401T DE 69930401 D1 DE69930401 D1 DE 69930401D1
Authority
DE
Germany
Prior art keywords
delivery systems
sufentanil
heat
transdermal analgesic
analgesic delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69930401T
Other languages
English (en)
Other versions
DE69930401T2 (de
Inventor
Jie Zhang
Hao Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zars Inc
Original Assignee
Zars Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zars Inc filed Critical Zars Inc
Publication of DE69930401D1 publication Critical patent/DE69930401D1/de
Application granted granted Critical
Publication of DE69930401T2 publication Critical patent/DE69930401T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4468Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • A61B2017/00765Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00089Wound bandages
    • A61F2013/00187Wound bandages insulating; warmth or cold applying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00089Wound bandages
    • A61F2013/00187Wound bandages insulating; warmth or cold applying
    • A61F2013/00204Wound bandages insulating; warmth or cold applying insulating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00902Plasters containing means
    • A61F2013/00906Plasters containing means for transcutaneous or transdermal drugs application
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00902Plasters containing means
    • A61F2013/0091Plasters containing means with disinfecting or anaesthetics means, e.g. anti-mycrobic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F7/03Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
    • A61F7/032Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction using oxygen from the air, e.g. pocket-stoves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F7/03Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
    • A61F7/032Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction using oxygen from the air, e.g. pocket-stoves
    • A61F7/034Flameless
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Vascular Medicine (AREA)
  • Thermal Sciences (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69930401T 1998-09-29 1999-09-15 Vorrichtung zur abgabe von fentanyl und sufentanil Expired - Fee Related DE69930401T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US162587 1998-09-29
US09/162,587 US6284266B1 (en) 1995-07-28 1998-09-29 Methods and apparatus for improved administration of fentanyl and sufentanil
PCT/US1999/021140 WO2000018338A1 (en) 1998-09-29 1999-09-15 Methods and apparatus for improved administration of fentanyl and sufentanil

Publications (2)

Publication Number Publication Date
DE69930401D1 true DE69930401D1 (de) 2006-05-11
DE69930401T2 DE69930401T2 (de) 2006-11-16

Family

ID=22586280

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69930401T Expired - Fee Related DE69930401T2 (de) 1998-09-29 1999-09-15 Vorrichtung zur abgabe von fentanyl und sufentanil

Country Status (11)

Country Link
US (1) US6284266B1 (de)
EP (1) EP1117356B1 (de)
JP (1) JP2002525297A (de)
CN (1) CN100402001C (de)
AT (1) ATE320233T1 (de)
AU (1) AU5924199A (de)
CA (1) CA2345494C (de)
DE (1) DE69930401T2 (de)
ES (1) ES2260936T3 (de)
HK (1) HK1040047A1 (de)
WO (1) WO2000018338A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6756053B2 (en) * 1995-07-28 2004-06-29 Zars, Inc. Controlled heat induced rapid delivery of pharmaceuticals from skin depot
US6245347B1 (en) * 1995-07-28 2001-06-12 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
US20020114827A1 (en) * 1995-07-28 2002-08-22 Jie Zhang Methods and apparatus for improved administration of analgesics
US20040265353A1 (en) * 1995-07-28 2004-12-30 Zars, Inc. Systems and methods for treating panic attacks
JP2003524652A (ja) * 2000-02-29 2003-08-19 ツァン,ツィエ 改良された経皮薬剤パッチ
US20020106407A1 (en) * 2000-12-11 2002-08-08 Dennis Coleman Method and apparatus for treating breakthrough pain
DE10102817B4 (de) * 2001-01-23 2006-01-12 Lts Lohmann Therapie-Systeme Ag Vorrichtung und Verfahren zur Hitzepulsgestützten transdermalen Applikation von Wirkstoffen
US6893453B2 (en) * 2002-12-17 2005-05-17 Kimberly-Clark Worldwide, Inc. Thermal therapy pad with variable heat control
US8524272B2 (en) 2003-08-15 2013-09-03 Mylan Technologies, Inc. Transdermal patch incorporating active agent migration barrier layer
GB0412793D0 (en) * 2004-06-09 2004-07-14 Boots Healthcare Int Ltd Therapeutic product
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
US9004059B2 (en) * 2006-08-10 2015-04-14 Rechargeable Battery Corporation Reusable heater in a package
CN101678169A (zh) 2007-03-19 2010-03-24 茵苏莱恩医药有限公司 药物输送设备
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
CA2681483C (en) * 2007-03-20 2015-09-22 Wyeth Thermal device
US8409133B2 (en) 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
KR20100129269A (ko) 2008-01-04 2010-12-08 엣지 시스템즈 코포레이션 피부 처리 장치 및 방법
RU2532893C2 (ru) 2008-11-07 2014-11-10 Инсьюлин Медикал Лтд. Устройство и способ доставки лекарственных средств
JP4934163B2 (ja) * 2009-03-18 2012-05-16 オカモト株式会社 皮膚貼付積層体
CA2757302A1 (en) * 2009-04-01 2010-10-07 Andrew Crockett Methods for treating myofascial, muscle, and/or back pain
WO2010129542A1 (en) * 2009-05-04 2010-11-11 Jie Zhang Methods of treating pains associated with neuroma, nerve entrapment, and other conditions
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia
EP3437575B1 (de) 2013-03-15 2021-04-21 Edge Systems LLC Vorrichtungen und systeme zur hautbehandlung
US20170231813A1 (en) * 2014-08-06 2017-08-17 Handy Technology (Zhuhai) Ltd. Self-heating thermal-insulation film and face mask and eye mask manufactured therefrom
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
EP4324414A3 (de) 2014-12-23 2024-05-01 HydraFacial LLC Vorrichtungen und verfahren zur hautbehandlung mit einem rollball oder einem dochtelement
US9650338B1 (en) 2016-07-29 2017-05-16 VDM Biochemicals, Inc. Opioid antagonist compounds and methods of making and using
EP3773828A4 (de) * 2018-03-28 2021-05-12 Needlecalm Pty Ltd Vorrichtung und system zur schmerzbehandlung
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929131A (en) 1975-01-09 1975-12-30 Thomas L Hardwick Bandage and method of using same
DE2823174A1 (de) 1977-07-06 1979-01-25 Astra Laekemedel Ab Arzneimittel fuer die prophylaktische behandlung postoperativer tiefer venenthrombose
SE7713618L (sv) 1977-12-01 1979-06-02 Astra Laekemedel Ab Lokalanestetisk blandning
US4230105A (en) 1978-11-13 1980-10-28 Merck & Co., Inc. Transdermal delivery of drugs
US4286592A (en) 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US5651768A (en) 1983-08-18 1997-07-29 Drug Delivery Systems, Inc. Transdermal drug applicator and electrodes therefor
US5605536A (en) 1983-08-18 1997-02-25 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
JPS60174716A (ja) 1984-02-21 1985-09-09 Yamanouchi Pharmaceut Co Ltd パツチ剤
GB2163956B (en) 1984-09-08 1988-03-30 Ile De France Percutaneous anaesthetic composition for topical application
US4747841A (en) 1985-03-19 1988-05-31 Yasuro Kuratomi Methods and instruments of moxibustion
US4693706A (en) 1986-08-11 1987-09-15 Mark L. Anderson Two compartment mixing syringe
DE3762480D1 (de) 1986-08-23 1990-06-07 Arno W Latzke Mittel zur applikation von transdermal resorbierbaren wirkstoffen.
US4911707A (en) 1987-02-13 1990-03-27 Ciba-Geigy Corporation Monolithic user-activated transdermal therapeutic system
GB8712518D0 (en) 1987-05-28 1987-07-01 Univ Belfast Unit-dose film composition
DK158336C (da) 1987-09-22 1990-10-01 Coloplast As Forbindsmateriale til behandling af saar samt smaalegemer til brug ved fremstilling deraf
US4830855A (en) 1987-11-13 1989-05-16 Landec Labs, Inc. Temperature-controlled active agent dispenser
JPH01122037U (de) 1988-02-12 1989-08-18
DE3806562A1 (de) 1988-03-01 1989-09-14 Alpha Therapeutic Gmbh Zweikammerspritze mit einer fuellung aus aktivitaetsempfindlichem humanen protein als wirkstoff
US4913957A (en) 1988-05-23 1990-04-03 Kimberly-Clark Corporation Thermal retaining fabric laminate
US5236714A (en) * 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
DE3903794A1 (de) 1989-02-09 1990-08-16 Lohmann Therapie Syst Lts Therapeutisches system zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung
US5217718A (en) 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5276032A (en) 1989-12-28 1994-01-04 King O Newton Vision aid and anesthetic composition
US5229133A (en) 1990-01-24 1993-07-20 Alza Corporation Delivery system comprising means for controlling internal pressure
US5279594A (en) 1990-05-23 1994-01-18 Jackson Richard R Intubation devices with local anesthetic effect for medical use
US5114411A (en) 1990-11-19 1992-05-19 Habley Medical Technology Corporation Multi-chamber vial
US5108710A (en) 1990-11-26 1992-04-28 Little Amy C Transdermal patch holder
US5580573A (en) 1991-02-01 1996-12-03 E. R. Squibb And Sons, Inc. Temperature activated controlled release
US5213129A (en) 1991-03-25 1993-05-25 Csb Limited Partnership Fluid mixing device
AU2782592A (en) * 1991-10-15 1993-05-21 Cygnus Therapeutic Systems Thermal enhancement of transdermal drug administration
US5329976A (en) 1991-12-09 1994-07-19 Habley Medical Technology Corporation Syringe-filling and medication mixing dispenser
DK168420B1 (da) 1992-03-27 1994-03-28 Coloplast As Varmebandage
CN1092330A (zh) * 1993-03-18 1994-09-21 孙金森 医疗止痛热敷袋
US5330452A (en) 1993-06-01 1994-07-19 Zook Gerald P Topical medicating device
US5534021A (en) 1994-09-01 1996-07-09 Dvoretzky; Israel Heating pad for providing heat therapy
EP0835086B1 (de) 1995-06-29 2003-08-27 The Procter & Gamble Company Nackenwärmepackung mit flügelform und mitteln zur lageeinhaltung
US5728058A (en) 1995-06-29 1998-03-17 The Procter & Gamble Company Elastic knee wrap
DK0835083T3 (da) 1995-06-29 2003-11-10 Procter & Gamble Elastisk rygomvikling, der har rombeformet varmemønster og antisliporgan
EP0835087B1 (de) 1995-06-29 2002-02-06 The Procter & Gamble Company Wärmezellen
US5658583A (en) 1995-07-28 1997-08-19 Zhang; Jie Apparatus and methods for improved noninvasive dermal administration of pharmaceuticals
US5906830A (en) 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
WO1997014473A1 (en) 1995-10-18 1997-04-24 Novartis Ag Thermopile powered transdermal drug delivery device
US5626571A (en) 1995-11-30 1997-05-06 The Procter & Gamble Company Absorbent articles having soft, strong nonwoven component
US5984995A (en) 1996-03-29 1999-11-16 The Procter & Gamble Company Heat cells
AU3136897A (en) * 1996-05-22 1997-12-09 Diversified Pharmaceuticals, Inc. Compositions, methods and devices for the transdermal delivery of drugs
US5674270A (en) 1996-06-27 1997-10-07 The Procter & Gamble Company Thermal pad having a common attachment and oxygen permeable side
WO1997049361A1 (en) 1996-06-27 1997-12-31 The Procter & Gamble Company Thermal pad having a common attachment and oxygen permeable side
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TR199901509T2 (xx) 1996-12-31 1999-09-21 The Procter & Gamble Company At�labilir termal boyun bandaj�
BR9714457A (pt) 1996-12-31 2000-03-21 Procter & Gamble Embalagem térmica dotada de várias células de aquecimento individuais
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EP1117356A4 (de) 2002-07-24
CA2345494A1 (en) 2000-04-06
DE69930401T2 (de) 2006-11-16
WO2000018338A1 (en) 2000-04-06
EP1117356B1 (de) 2006-03-15
CN100402001C (zh) 2008-07-16
JP2002525297A (ja) 2002-08-13
AU5924199A (en) 2000-04-17
EP1117356A1 (de) 2001-07-25
CA2345494C (en) 2007-08-21
CN1331575A (zh) 2002-01-16
ATE320233T1 (de) 2006-04-15
US6284266B1 (en) 2001-09-04
HK1040047A1 (zh) 2002-05-24
ES2260936T3 (es) 2006-11-01

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