JP4750222B2
(ja)
*
|
1998-09-03 |
2011-08-17 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
JP4689781B2
(ja)
*
|
1998-09-03 |
2011-05-25 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
GB0024444D0
(en)
*
|
2000-10-05 |
2000-11-22 |
Glaxo Group Ltd |
Novel protein
|
AU2002310256A1
(en)
*
|
2001-06-05 |
2002-12-16 |
Exelixis Inc. |
Ppp2cs as modifiers of the p53 pathway and methods of use
|
CA2633413C
(en)
|
2001-06-20 |
2012-08-21 |
Genentech, Inc. |
Antibodies against tumor-associated antigenic target (tat) polypeptides
|
US20050272120A1
(en)
|
2001-06-20 |
2005-12-08 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
US7803915B2
(en)
*
|
2001-06-20 |
2010-09-28 |
Genentech, Inc. |
Antibody compositions for the diagnosis and treatment of tumor
|
DE60236307D1
(de)
|
2001-09-28 |
2010-06-17 |
Pharma Co Ltd J |
Erender natriumunabhängiger transporter, dessen gen mittels konstruktion von die spezifizierung der funktion ermöglichenden fusionsproteinen
|
JP4278906B2
(ja)
*
|
2002-02-18 |
2009-06-17 |
ジェイファーマ株式会社 |
酸性アミノ酸を輸送するナトリウム非依存性トランスポーター及びその遺伝子
|
EP1499741A4
(de)
*
|
2002-03-13 |
2006-07-05 |
Univ Creighton |
Vorrichtung und verfahren zum nachweis antibiotisch-inaktivierender enzyme
|
EP1483962A3
(de)
*
|
2003-06-06 |
2005-01-12 |
F. Hoffmann-La Roche Ag |
Transgenes Tiermodel für Glyt1 Funktion
|
CA2469992A1
(en)
*
|
2003-06-06 |
2004-12-06 |
F. Hoffmann-La Roche Ag |
Transgenic animal model for glyt1 function
|
DK2489364T3
(en)
|
2003-11-06 |
2015-03-02 |
Seattle Genetics Inc |
Monomethylvaline compounds conjugated to antibodies
|
US7462459B2
(en)
*
|
2004-01-30 |
2008-12-09 |
Xenoport, Inc. |
LAT1 transporters expressed in blood brain barrier cells
|
JP4560314B2
(ja)
*
|
2004-03-17 |
2010-10-13 |
ジェイファーマ株式会社 |
中性アミノ酸トランスポーターによる癌の検出法、及びそのためのキット
|
AU2005249490B2
(en)
|
2004-06-01 |
2010-07-29 |
Genentech, Inc. |
Antibody drug conjugates and methods
|
US20060003920A1
(en)
*
|
2004-06-04 |
2006-01-05 |
Xenoport, Inc. |
LAT1 transporters expressed in cancer cells
|
AU2005286607B2
(en)
|
2004-09-23 |
2011-01-27 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
WO2007084715A2
(en)
*
|
2006-01-19 |
2007-07-26 |
Caprion Pharmaceuticals, Inc. |
Tat-031 and methods of assessing and treating cancer
|
TWI390034B
(zh)
|
2006-04-06 |
2013-03-21 |
Kyowa Hakko Kirin Co Ltd |
Novel anti-CD98 antibody
|
CN105372425A
(zh)
*
|
2007-02-06 |
2016-03-02 |
J制药股份有限公司 |
前列腺癌的恶性程度判定试剂盒和其方法
|
JPWO2008096416A1
(ja)
*
|
2007-02-06 |
2010-05-20 |
ジェイファーマ株式会社 |
前立腺がんの悪性度判定キット及びその方法
|
US7935494B2
(en)
*
|
2007-03-01 |
2011-05-03 |
Carnegie Institution Of Washington |
Trp/his exchange and kynurenine induced Trp transport
|
RU2523419C2
(ru)
|
2008-07-15 |
2014-07-20 |
Дженетек, Инк. |
Конъюгаты производного антрациклина, способы их получения и их применение в качестве противоопухолевых соединений
|
EP2459064A1
(de)
*
|
2009-07-27 |
2012-06-06 |
Cardiac Pacemakers, Inc. |
Medizinische vorrichtung zur behandlung von herzinsuffizienz mittels umverteilung des blutvolumens
|
CA2809819A1
(en)
|
2009-09-09 |
2011-03-17 |
Centrose, Llc |
Extracellular targeted drug conjugates
|
CN103038255A
(zh)
|
2010-03-26 |
2013-04-10 |
国立大学法人德岛大学 |
新抗cd98抗体及其用途
|
US9021394B2
(en)
*
|
2010-04-01 |
2015-04-28 |
Eventsq Llc |
Capturing user feedback of software content in a networked environment and controlling the software using a single action
|
EP2528625B1
(de)
|
2010-04-15 |
2013-07-10 |
Spirogen Sàrl |
Pyrrolobenzodiazepine und konjugate daraus
|
CA2799540A1
(en)
|
2010-06-08 |
2011-12-15 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
JP5866138B2
(ja)
*
|
2010-10-28 |
2016-02-17 |
幸雄 米田 |
骨粗鬆症の予防及び/又は治療剤、骨吸収抑制剤、骨形成促進剤及びそれらのスクリーニング方法
|
CN103313990B
(zh)
|
2010-11-17 |
2016-07-20 |
基因泰克公司 |
丙氨酰美登醇抗体偶联物
|
KR101976219B1
(ko)
|
2011-04-15 |
2019-05-07 |
제이 파마 가부시끼가이샤 |
유방암의 바이오마커
|
WO2012155019A1
(en)
|
2011-05-12 |
2012-11-15 |
Genentech, Inc. |
Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature pepides
|
BR112014009050B1
(pt)
|
2011-10-14 |
2022-06-21 |
Medimmune Limited |
Conjugado anticorpo-fármaco de pirrolbenzodiazepinas, composição farmacêutica que compreende o mesmo, bem como compostos de pirrolbenzodiazepinas
|
WO2013130093A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
|
US10695433B2
(en)
|
2012-10-12 |
2020-06-30 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
NZ707490A
(en)
|
2012-10-12 |
2018-09-28 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-anti-cd22 antibody conjugates
|
CA2887894C
(en)
|
2012-10-12 |
2019-10-29 |
Adc Therapeutics Sarl |
Pyrrolobenzodiazepine - anti-psma antibody conjugates
|
LT2839860T
(lt)
|
2012-10-12 |
2019-07-10 |
Medimmune Limited |
Pirolobenzodiazepinai ir jų konjugatai
|
NZ707534A
(en)
|
2012-10-12 |
2018-08-31 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
KR101995620B1
(ko)
|
2012-10-12 |
2019-07-03 |
에이디씨 테라퓨틱스 에스에이 |
피롤로벤조디아제핀-항체 컨주게이트
|
US10736903B2
(en)
|
2012-10-12 |
2020-08-11 |
Medimmune Limited |
Pyrrolobenzodiazepine-anti-PSMA antibody conjugates
|
JP2013063978A
(ja)
*
|
2012-10-24 |
2013-04-11 |
J-Pharma Co Ltd |
抗ヒトlat1モノクローナル抗体及び前立腺がんの悪性度判定キット
|
AU2013366493B2
(en)
|
2012-12-21 |
2017-08-24 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
EA032986B1
(ru)
|
2012-12-21 |
2019-08-30 |
Медимьюн Лимитед |
Пирролобензодиазепины
|
TWI680766B
(zh)
|
2013-03-13 |
2020-01-01 |
英商梅迪繆思有限公司 |
吡咯并苯并二氮呯及其共軛物
|
JP6340019B2
(ja)
|
2013-03-13 |
2018-06-06 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピン及びそのコンジュゲート
|
BR112015023333A8
(pt)
|
2013-03-13 |
2018-04-17 |
Medimmune Ltd |
pirrolbenzodiazepinas e conjugados dos mesmos
|
KR20160042080A
(ko)
|
2013-08-12 |
2016-04-18 |
제넨테크, 인크. |
1-(클로로메틸)-2,3-디히드로-1H-벤조[e]인돌 이량체 항체-약물 접합체 화합물, 및 사용 및 치료 방법
|
WO2015052535A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
EP3054985B1
(de)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepin-antikörper-konjugate
|
WO2015052532A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
MX2016007578A
(es)
|
2013-12-16 |
2016-10-03 |
Genentech Inc |
Compuestos de conjugado anticuerpo-farmaco dimerico de 1-(clorometil)-2,3-dihidro-1h-benzo [e] indol, y metodos de uso y tratamiento.
|
MX371092B
(es)
|
2013-12-16 |
2020-01-16 |
Genentech Inc |
Compuestos peptidomimeticos y conjugados de anticuerpo-farmaco de los mismos.
|
BR112016013861A2
(pt)
|
2013-12-16 |
2017-10-10 |
Genentech Inc |
conjugados de droga e anticorpo, compostos, método de tratamento e composição farmacêutica
|
JP6531166B2
(ja)
|
2014-09-10 |
2019-06-12 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピン及びそのコンジュゲート
|
US10149913B2
(en)
|
2014-09-12 |
2018-12-11 |
Genentech, Inc. |
Anthracycline disulfide intermediates, antibody-drug conjugates and methods
|
TW201625688A
(zh)
|
2014-09-12 |
2016-07-16 |
建南德克公司 |
經半胱胺酸改造之抗體及接合物
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
PE20170905A1
(es)
|
2014-09-17 |
2017-07-12 |
Genentech Inc |
Pirrolobenzodiazepinas y conjugados de anticuerpo-disulfuro de las mismas
|
CN107148285B
(zh)
|
2014-11-25 |
2022-01-04 |
Adc治疗股份有限公司 |
吡咯并苯并二氮杂䓬-抗体缀合物
|
WO2016090050A1
(en)
|
2014-12-03 |
2016-06-09 |
Genentech, Inc. |
Quaternary amine compounds and antibody-drug conjugates thereof
|
JP2015134778A
(ja)
*
|
2015-02-06 |
2015-07-27 |
ジェイファーマ株式会社 |
抗ヒトlat1モノクローナル抗体及び前立腺がんの悪性度判定キット
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
CN108700598A
(zh)
|
2016-03-25 |
2018-10-23 |
豪夫迈·罗氏有限公司 |
多路总抗体和抗体缀合的药物量化测定法
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
CN109152843A
(zh)
|
2016-05-20 |
2019-01-04 |
豪夫迈·罗氏有限公司 |
Protac抗体缀合物及其使用方法
|
EP3465221B1
(de)
|
2016-05-27 |
2020-07-22 |
H. Hoffnabb-La Roche Ag |
Bioanalytisches verfahren zur charakterisierung von ortsspezifischen antikörper-wirkstoff-konjugaten
|
US10639378B2
(en)
|
2016-06-06 |
2020-05-05 |
Genentech, Inc. |
Silvestrol antibody-drug conjugates and methods of use
|
CN109689111B
(zh)
|
2016-08-11 |
2024-04-05 |
基因泰克公司 |
吡咯并苯并二氮杂䓬前药及其抗体缀合物
|
EP3522933B1
(de)
|
2016-10-05 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Verfahren zur herstellung von antikörperarzneimittelkonjugaten
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
PT3544636T
(pt)
|
2017-02-08 |
2021-05-04 |
Medimmune Ltd |
Conjugados de anticorpos-pirrolobenzodiazepinas
|
HUE059828T2
(hu)
|
2017-04-18 |
2023-01-28 |
Medimmune Ltd |
Pirrolobenzodiazepin konjugátumok
|
CA3057748A1
(en)
|
2017-04-20 |
2018-10-25 |
Adc Therapeutics Sa |
Combination therapy with an anti-axl antibody-drug conjugate
|
BR112019026564A2
(pt)
|
2017-06-14 |
2020-06-30 |
Adc Therapeutics Sa |
regimes de dosagem para a administração de um adc anti-cd19
|
SI3668874T1
(sl)
|
2017-08-18 |
2022-04-29 |
Medimmune Limited |
Pirolobenzodiazepinski konjugati
|
KR20220156974A
(ko)
|
2017-09-20 |
2022-11-28 |
주식회사 피에이치파마 |
타일란스타틴 유사체
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
AU2019365238A1
(en)
|
2018-10-24 |
2021-05-13 |
F. Hoffmann-La Roche Ag |
Conjugated chemical inducers of degradation and methods of use
|
JP2022513198A
(ja)
|
2018-12-10 |
2022-02-07 |
ジェネンテック, インコーポレイテッド |
Fc含有タンパク質への部位特異的コンジュゲーションのための光架橋性ペプチド
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
WO2024138128A2
(en)
|
2022-12-23 |
2024-06-27 |
Genentech, Inc. |
Cereblon degrader conjugates, and uses thereof
|