DE69924142D1 - Kirschextrakte zur hemmung von cyclooxygenaseenzymen - Google Patents

Kirschextrakte zur hemmung von cyclooxygenaseenzymen

Info

Publication number
DE69924142D1
DE69924142D1 DE69924142T DE69924142T DE69924142D1 DE 69924142 D1 DE69924142 D1 DE 69924142D1 DE 69924142 T DE69924142 T DE 69924142T DE 69924142 T DE69924142 T DE 69924142T DE 69924142 D1 DE69924142 D1 DE 69924142D1
Authority
DE
Germany
Prior art keywords
cycles
inhibiting cyclooxygenase
cherry
cherry extracts
extracts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69924142T
Other languages
English (en)
Other versions
DE69924142T2 (de
Inventor
G Nair
Haibo Wang
M Strasburg
M Booren
I Gray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Michigan State University MSU
Original Assignee
Michigan State University MSU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/317,310 external-priority patent/US6423365B1/en
Application filed by Michigan State University MSU filed Critical Michigan State University MSU
Application granted granted Critical
Publication of DE69924142D1 publication Critical patent/DE69924142D1/de
Publication of DE69924142T2 publication Critical patent/DE69924142T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Botany (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69924142T 1998-12-11 1999-12-10 Kirschextrakte zur hemmung von cyclooxygenaseenzymen Expired - Fee Related DE69924142T2 (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US11194598P 1998-12-11 1998-12-11
US111945P 1998-12-11
US12017899P 1999-02-16 1999-02-16
US120178P 1999-02-16
US317310 1999-05-24
US09/317,310 US6423365B1 (en) 1998-12-11 1999-05-24 Method and compositions producing cherry derived products
US09/337,313 US6194469B1 (en) 1998-12-11 1999-06-21 Method for inhibiting cyclooxygenase and inflammation using cherry bioflavonoids
US337313 1999-06-21
PCT/US1999/029261 WO2000033824A2 (en) 1998-12-11 1999-12-10 Bioflavonoids, anthocyanins and phenolic compounds from cherries for inhibiting inflammation

Publications (2)

Publication Number Publication Date
DE69924142D1 true DE69924142D1 (de) 2005-04-14
DE69924142T2 DE69924142T2 (de) 2005-08-18

Family

ID=27493826

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69924142T Expired - Fee Related DE69924142T2 (de) 1998-12-11 1999-12-10 Kirschextrakte zur hemmung von cyclooxygenaseenzymen

Country Status (10)

Country Link
US (3) US6194469B1 (de)
EP (1) EP1137429B1 (de)
JP (1) JP2002531493A (de)
CN (1) CN1335775A (de)
AT (1) ATE290395T1 (de)
AU (1) AU2172100A (de)
CA (1) CA2354042C (de)
DE (1) DE69924142T2 (de)
TW (1) TWI245629B (de)
WO (1) WO2000033824A2 (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277978B1 (en) 1995-12-22 2001-08-21 University Of Utah Research Foundation KVLQT1—a long QT syndrome gene
US6194469B1 (en) * 1998-12-11 2001-02-27 Board Of Trustees Operating Michigan State Univeristy Method for inhibiting cyclooxygenase and inflammation using cherry bioflavonoids
JP4100871B2 (ja) * 1998-12-11 2008-06-11 ミシガン ステイト ユニヴァーシティー タルトチェリー誘導製品を製造するための方法及び組成物
US20010024664A1 (en) * 1999-03-19 2001-09-27 Obukowicz Mark G. Selective COX-2 inhibition from edible plant extracts
US20020160060A1 (en) * 1999-04-26 2002-10-31 Mandy Kim Chen Enriched spreads
US6210701B1 (en) 1999-04-30 2001-04-03 Healthcomm International, Inc. Medical food for treating inflammation-related diseases
AU4402600A (en) * 1999-05-18 2000-12-05 Rawlings, Anthony V. Fat containing products
KR100318223B1 (ko) * 1999-07-05 2001-12-22 김찬식 페피노 추출물을 함유하는 혈중알콜농도 저하용 조성물 및 그 제조방법
JP2003508415A (ja) * 1999-08-27 2003-03-04 ミシガン ステイト ユニヴァーシティー 天然シクロオキシゲナーゼ阻害剤を含有する食物サプリメント
KR100371971B1 (ko) * 1999-09-30 2003-02-14 주식회사 펩트론 천연물 유래 화합물 라이브러리의 제조방법
US6806257B1 (en) * 1999-10-20 2004-10-19 Board Of Trustees Of Southern Illinois University Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators
EP1104672A1 (de) * 1999-12-02 2001-06-06 Laboratoires Serobiologiques(Societe Anonyme) Kosmetische und/oder pharmazeutische Zubereitungen
US20040053859A1 (en) * 2000-08-11 2004-03-18 Tomoyuki Shirai Preventive or therapeutic agent for cancer containing cyanidin compound as active ingredient
EP1180331B1 (de) * 2000-08-16 2008-07-09 Unilever N.V. Mischungen von Isoflavonen und Flavonen
DE60134702D1 (de) 2000-08-16 2008-08-21 Unilever Nv Mischungen von Isoflavonen und Flavonen
US6780442B2 (en) * 2000-08-31 2004-08-24 Hauser, Inc. Efficient method for producing compositions enriched in anthocyanins
US6960360B2 (en) * 2000-08-31 2005-11-01 Phenolics, Llc Efficient method for producing compositions enriched in total phenols
US7306815B2 (en) * 2000-08-31 2007-12-11 Phenolics, Llc Compositions enriched in phenolic compounds and methods for producing the same
AU770436B2 (en) * 2000-09-22 2004-02-19 Unilever Plc Use of prenylated flavones
EP1190630A1 (de) * 2000-09-22 2002-03-27 Unilever N.V. Verwendung von prenylierten Flavonen
AU2001296402A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
WO2002047706A2 (en) * 2000-12-15 2002-06-20 Pharmacia Corporation Selective cox-2 inhibition from plant extracts
US7338971B2 (en) * 2001-08-30 2008-03-04 El-Naggar Mawaheb M Treatment of inflammatory, cancer, and thrombosis disorders
US8337914B2 (en) * 2002-02-27 2012-12-25 Access Business Group International Llc Dietary food supplement containing natural cyclooxygenase inhibitors and methods for inhibiting pain and inflammation
US7108868B2 (en) 2002-03-22 2006-09-19 Unigen Pharmaceuticals, Inc. Isolation of a dual cox-2 and 5-lipoxygenase inhibitor from acacia
US7972632B2 (en) 2003-02-28 2011-07-05 Unigen Pharmaceuticals, Inc. Identification of Free-B-Ring flavonoids as potent COX-2 inhibitors
CA2484192C (en) * 2002-04-30 2012-10-02 Unigen Pharmaceuticals, Inc. Formulation of a mixture of free-b-ring flavonoids and flavans as a therapeutic agent
US8034387B2 (en) 2002-04-30 2011-10-11 Unigen, Inc. Formulation of a mixture of free-B-ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments
CN1791418B (zh) * 2003-03-21 2012-03-07 K2A公司 Jucara和a*ai果实基营养补充剂
US20070184135A1 (en) * 2003-03-26 2007-08-09 Palu Afa K Morinda citrifolia-based formulation 5-LOX and 15-LOX
BRPI0409199A (pt) * 2003-04-04 2006-05-02 Cellmics Co Ltd composição para a prevenção ou tratamento de doenças alérgicas usando extrato de arroz preto e seu uso terapêutico
BRPI0409179A (pt) 2003-04-04 2006-05-02 Unigen Pharmaceuticals Inc formulação de inibidores duplos de ciclooxigenase (cox) e lipoxigenase (lox) para cuidados com a pele de mamìferos
US7744943B2 (en) * 2003-05-12 2010-06-29 Grand Brands, LLC Edible mix and method of making the same
US20050261197A1 (en) * 2004-05-19 2005-11-24 Henry Aoki Coffee bean extract, method of extraction and composition containing the same
US20060073220A1 (en) * 2004-07-08 2006-04-06 Daugherty F J Cinnamon extract enriched for polyphenols and methods of preparing same
US7737121B2 (en) * 2004-07-29 2010-06-15 Board Of Trustees Of Michigan State University Insulin secretion by anthocyanins and anthocyanidins
US20100160244A1 (en) * 2004-09-02 2010-06-24 Marcel Nimni Methods and compositions for enhancing collagen, proteoglycan, and glutathione synthesis in the skin
US7598291B2 (en) * 2004-09-02 2009-10-06 Marcel Nimni Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin
GB2424833B (en) * 2005-04-08 2008-12-10 Nicholas John Larkins Anti-inflammatory formulation comprising apocyanin and paeonol
US8367126B2 (en) 2005-09-27 2013-02-05 University Of Kentucky Research Foundation Berry preparations and extracts
US7964223B2 (en) * 2005-09-27 2011-06-21 University Of Kentucky Research Foundation Berry preparations and extracts
JP5303697B2 (ja) * 2005-10-26 2013-10-02 オリザ油化株式会社 抗炎症剤
US20070248694A1 (en) * 2006-04-25 2007-10-25 Phytomyco Research Corporation Anti-inflammatory properties of a standardized extract from Euphorbia hirta (PM-251) activity and for treating conditions of inflammation
KR100785466B1 (ko) 2006-05-09 2007-12-13 (주)천년약속 검정콩으로부터 추출한 안토시아닌을 함유하는 의약 조성물
US20080031869A1 (en) * 2006-08-02 2008-02-07 Fontaine Juliette S Pain relief composition
US20100047371A1 (en) * 2006-08-29 2010-02-25 Mumper Russell J Compositions and methods for oral cancer chemoprevention using berry preparations and extracts
KR100832240B1 (ko) 2007-04-11 2008-05-28 경상대학교산학협력단 검정콩 껍질로부터 추출한 안토시아닌을 함유하는 창상치료용 의약 조성물
KR100880876B1 (ko) 2007-04-11 2009-01-30 경상대학교산학협력단 검정콩 껍질로부터 추출한 안토시아닌을 함유하는 피판이나조직의 허혈-재관류 손상의 예방 또는 치료용 의약 조성물
US10376550B2 (en) 2007-12-12 2019-08-13 Dacy Tech Pty Ltd. Nutraceutical composition and methods of use
KR101564056B1 (ko) * 2007-12-12 2015-10-28 데이씨 테크 피티와이 리미티드 기능식품 조성물 및 용도 방법
US20090269425A1 (en) * 2008-04-28 2009-10-29 Truscott Kent J Formulation and method for relieving or preventing symptoms associated with uric acid crystals
US9000033B2 (en) * 2008-07-31 2015-04-07 Arch Personal Care Products, L.P. Composition for improving skin condition and appearance
US8133436B2 (en) 2008-08-05 2012-03-13 Howmedica Osteonics Corp. Polyethylene cross-linked with an anthocyanin
JP2010105975A (ja) * 2008-10-31 2010-05-13 Okayama Univ ヤマブドウ由来の腫瘍発生抑制剤
CA2746652C (en) * 2008-12-11 2018-03-06 Axcentua Pharmaceuticals Ab Crystalline forms of genistein
BRPI1008607B1 (pt) 2009-02-23 2017-04-18 Unilever Nv composição cosmética comestível para o tratamento da pele envelhecida, método cosmético para proporcionar benefícios para a pele, e, usos da referida composição.
JP6101077B2 (ja) 2009-04-20 2017-03-22 ガレンバイオ、インコーポレイテッド 生体分子を細胞へトランスフェクトするための組成物
SG10201500620PA (en) 2009-07-24 2015-03-30 Amazentis Sa Compounds, compositions and methods for protecting brain health in neurodegenerative disorders
JP5744529B2 (ja) * 2011-01-13 2015-07-08 株式会社コーセー メラニン生成抑制剤
CN103156837B (zh) * 2013-03-27 2015-04-15 许翔 类黄酮在制药中的应用
KR101989012B1 (ko) * 2013-08-14 2019-06-13 주식회사 엘지생활건강 피부 재생, 주름개선, 항산화, 항염증 및 피부 미백용 조성물
JP2015051934A (ja) * 2013-09-05 2015-03-19 地方独立行政法人青森県産業技術センター 皮膚の酸化的ストレス抑制剤
CN104892700A (zh) * 2015-06-11 2015-09-09 威海紫光科技园有限公司 樱桃中花色苷的提取制备方法
US11541094B2 (en) 2019-08-06 2023-01-03 Healthrite Partners, LLC Formulations for treating metabolic syndrome and increasing energy levels
WO2021197971A1 (en) * 2020-04-01 2021-10-07 Evonik Operations Gmbh Preparation for use as antioxidant
US20230330172A1 (en) * 2020-08-25 2023-10-19 National University Corporation Kumamoto University Composition for ameliorating unpleasant state caused by menstruation
CN114288216A (zh) * 2021-12-16 2022-04-08 优颜皮肤科学研究(广州)有限公司 一种抗氧化抗糖化组合物及其制备方法
HUP2200188A1 (hu) * 2022-05-30 2023-12-28 Debreceni Egyetem Komplex meggyextraktum és eljárás ilyen extraktum elõállítására

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL241315A (de) 1958-07-18
GB1589294A (en) 1976-09-08 1981-05-13 Inverni Della Beffa Spa Pharmaceutical compositions containing anthocyanidines
US4439458A (en) 1982-04-26 1984-03-27 The Coca-Cola Company Preparation of citrus juices, concentrates and dried powders which are reduced in bitterness
US4712310A (en) * 1986-09-15 1987-12-15 E. I. Du Pont De Nemours And Company Co-spray technique
US5266685A (en) 1992-05-05 1993-11-30 Grain Processing Corporation Non-bitter protein hydrolyzates
US5691360A (en) * 1993-12-08 1997-11-25 Alcon Laboratories, Inc. Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents
US5462932A (en) * 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
US5908650A (en) * 1995-10-20 1999-06-01 Hauser, Inc. Pigment composition containing anthocyanins stabilized by plant extracts
JPH09151198A (ja) * 1995-11-30 1997-06-10 Nippon Mektron Ltd 鎮痛抗炎症剤
US5665783A (en) 1996-02-08 1997-09-09 Ecotech Recyclable regenerant for weak acid ion exhange resins
US5817354A (en) 1996-08-22 1998-10-06 Sepragen Corporation High throughput debittering
DE19720767A1 (de) * 1997-05-07 1998-11-12 Protekum Umweltinstitut Gmbh O Pharmazeutisches Produkt, insbesondere zur Therapie und Prophylaxe von Herz-Kreislauf-Erkrankungen
US6194469B1 (en) * 1998-12-11 2001-02-27 Board Of Trustees Operating Michigan State Univeristy Method for inhibiting cyclooxygenase and inflammation using cherry bioflavonoids
US6676978B1 (en) * 1999-02-16 2004-01-13 Board Of Trustees Of Michigan State University Method and compositions for producing berry derived products
US6818234B1 (en) * 1999-08-27 2004-11-16 Access Business Group International Llc Dietary food supplement containing natural cyclooxygenase inhibitors and methods for inhibiting pain and inflammation

Also Published As

Publication number Publication date
DE69924142T2 (de) 2005-08-18
AU2172100A (en) 2000-06-26
EP1137429A2 (de) 2001-10-04
WO2000033824A3 (en) 2000-08-10
US6576271B2 (en) 2003-06-10
WO2000033824A2 (en) 2000-06-15
JP2002531493A (ja) 2002-09-24
US20010002407A1 (en) 2001-05-31
CA2354042C (en) 2009-02-03
CA2354042A1 (en) 2000-06-15
TWI245629B (en) 2005-12-21
EP1137429B1 (de) 2005-03-09
CN1335775A (zh) 2002-02-13
ATE290395T1 (de) 2005-03-15
US20010020009A1 (en) 2001-09-06
US6194469B1 (en) 2001-02-27

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