DE69924133D1 - Diethylentriaminpentaessigsäure enthaltende propofol-zusammensetzung - Google Patents
Diethylentriaminpentaessigsäure enthaltende propofol-zusammensetzungInfo
- Publication number
- DE69924133D1 DE69924133D1 DE69924133T DE69924133T DE69924133D1 DE 69924133 D1 DE69924133 D1 DE 69924133D1 DE 69924133 T DE69924133 T DE 69924133T DE 69924133 T DE69924133 T DE 69924133T DE 69924133 D1 DE69924133 D1 DE 69924133D1
- Authority
- DE
- Germany
- Prior art keywords
- pentacic
- diethylenetriamine
- acid containing
- containing propofol
- propofol composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
- Polyethers (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/176,881 US6028108A (en) | 1998-10-22 | 1998-10-22 | Propofol composition comprising pentetate |
PCT/US1999/024906 WO2000023050A1 (en) | 1998-10-22 | 1999-10-21 | Propofol composition comprising pentetate |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69924133D1 true DE69924133D1 (de) | 2005-04-14 |
Family
ID=22646263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69924133T Expired - Lifetime DE69924133D1 (de) | 1998-10-22 | 1999-10-21 | Diethylentriaminpentaessigsäure enthaltende propofol-zusammensetzung |
Country Status (17)
Country | Link |
---|---|
US (1) | US6028108A (de) |
EP (1) | EP1124536B1 (de) |
JP (1) | JP2002527465A (de) |
KR (1) | KR20010080263A (de) |
CN (1) | CN1331582A (de) |
AT (1) | ATE290367T1 (de) |
AU (1) | AU1226400A (de) |
BR (1) | BR9914725A (de) |
CA (1) | CA2347118A1 (de) |
CZ (1) | CZ20011420A3 (de) |
DE (1) | DE69924133D1 (de) |
EA (1) | EA003771B1 (de) |
IL (1) | IL142555A0 (de) |
NO (1) | NO20011967L (de) |
NZ (1) | NZ511149A (de) |
PL (1) | PL347395A1 (de) |
WO (1) | WO2000023050A1 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6749868B1 (en) | 1993-02-22 | 2004-06-15 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
DE69912441T2 (de) * | 1998-08-19 | 2004-08-19 | Skyepharma Canada Inc., Verdun | Injizierbare wässerige propofoldispersionen |
US6177477B1 (en) * | 1999-03-24 | 2001-01-23 | American Home Products Corporation | Propofol formulation containing TRIS |
JP2002541087A (ja) * | 1999-04-05 | 2002-12-03 | バクスター・インターナショナル・インコーポレイテッド | 防腐添加剤を含有するプロポフォール組成物 |
US6726919B2 (en) | 2000-06-16 | 2004-04-27 | Rtp Pharma, Inc. | Injectable dispersion of propofol |
US20030054042A1 (en) * | 2001-09-14 | 2003-03-20 | Elaine Liversidge | Stabilization of chemical compounds using nanoparticulate formulations |
ATE522498T1 (de) * | 2002-01-25 | 2011-09-15 | Theravance Inc | Sedative hypnotisch wirkende verbindungen mit kurzer wirkungsdauer zur anaesthesie und sedierung |
US20080220075A1 (en) * | 2002-03-20 | 2008-09-11 | Elan Pharma International Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
WO2003080027A1 (en) * | 2002-03-20 | 2003-10-02 | Elan Pharma International, Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
AU2003222491A1 (en) * | 2002-05-02 | 2003-12-31 | Fdl, Inc. | Novel parenteral composition comprising propofol |
EP1555976A4 (de) * | 2002-10-29 | 2007-11-14 | Transform Pharmaceuticals Inc | Propofol mit cystein |
AU2003299590B8 (en) | 2002-12-09 | 2010-04-08 | Abraxis Bioscience, Llc | Compositions and methods of delivery of pharmacological agents |
US20040225022A1 (en) * | 2003-05-09 | 2004-11-11 | Desai Neil P. | Propofol formulation containing reduced oil and surfactants |
US8476010B2 (en) | 2003-07-10 | 2013-07-02 | App Pharmaceuticals Llc | Propofol formulations with non-reactive container closures |
ES2332514T3 (es) * | 2003-07-23 | 2010-02-08 | Theravance, Inc. | Composiciones farmaceuticas de un agente hipnotico sedante de accion corta. |
US8546453B2 (en) | 2003-08-14 | 2013-10-01 | Rensheng Zhang | Propofol compositions and methods for reducing pain associated with propofol injection |
WO2006030450A2 (en) * | 2004-09-13 | 2006-03-23 | Bharat Serums & Vaccines Ltd. | Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy |
US8557861B2 (en) * | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
WO2007000662A2 (en) * | 2005-02-03 | 2007-01-04 | Taro Pharmaceuticals U.S.A., Inc. | Novel propofol composition comprising ascorbic acid or pharmaceutically acceptable salts thereof |
CN100358513C (zh) * | 2005-04-07 | 2008-01-02 | 常州市第四制药厂有限公司 | 一种丙泊酚注射液的制备工艺 |
WO2006112276A1 (ja) * | 2005-04-13 | 2006-10-26 | Otsuka Pharmaceutical Factory, Inc. | プロポフォール含有脂肪乳剤 |
WO2006128088A1 (en) * | 2005-05-27 | 2006-11-30 | Sandhya Goyal | Novel propofol composition comprising a pharmaceutically acceptable salt of formaldehyde sulfoxylate |
US20070031482A1 (en) * | 2005-08-02 | 2007-02-08 | Ceramoptec Industries, Ind. | PDT treatment method for cellulites and cosmetic use |
DE602006004887D1 (de) * | 2005-08-05 | 2009-03-05 | Bharat Serums & Vaccines Ltd | Intravenöse propofol-emulsionszusammensetzungen mit konservierendem effekt |
AU2006310044A1 (en) * | 2005-08-12 | 2007-05-10 | Bharat Serums & Vaccines Ltd. | Aqueous anaesthetic compositions comprising propofol |
BRPI0615265A8 (pt) * | 2005-08-31 | 2018-03-06 | Abraxis Bioscience Llc | composições compreendendo agentes farmacêuticos pouco hidrossoluíveis e agentes antimicrobianos |
JP5368093B2 (ja) * | 2005-08-31 | 2013-12-18 | アブラクシス バイオサイエンス, エルエルシー | 増大した安定性を有する難水溶性薬剤の組成物および調製の方法 |
TWI376239B (en) * | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
WO2008023384A1 (en) * | 2006-08-24 | 2008-02-28 | Bharat Serums & Vaccines Ltd. | Propofol emulsion compositions for intravenous administration |
US9132090B2 (en) | 2009-01-13 | 2015-09-15 | Chetan Majmudar | Propofol based anesthetic with preservative |
AU2013263292B2 (en) | 2012-05-16 | 2018-03-08 | Maninder SANDHU | Pharmaceutical compositions for the delivery of substantially water-insoluble drugs |
WO2014033751A2 (en) * | 2012-08-16 | 2014-03-06 | Emcure Pharmaceuticals Limited | Pharmaceutical composition of propofol |
WO2017017693A1 (en) | 2015-07-24 | 2017-02-02 | Neon Laboratories Limited | Stabilized injectable emulsion of propofol and ketamine |
WO2017031261A1 (en) | 2015-08-20 | 2017-02-23 | Mewa Singh | Polyphenolic polymer to make water-insoluble molecules become water-soluble |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1472793A (en) * | 1974-03-28 | 1977-05-04 | Ici Ltd | Pharmaceutical compositions |
US4798846A (en) * | 1974-03-28 | 1989-01-17 | Imperial Chemical Industries Plc | Pharmaceutical compositions |
JPS61204137A (ja) * | 1985-03-06 | 1986-09-10 | Yutaka Mizushima | 放射性造影剤 |
GB9405593D0 (en) * | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
US5614170A (en) * | 1994-11-30 | 1997-03-25 | Hemagen/Pfc | Paramagnetic complexes of N-alkyl-N-hydroxylamides of organic acids and emulsions containing same for magnetic resonance imaging (MRI) |
JP2868206B2 (ja) * | 1996-04-16 | 1999-03-10 | 株式会社オフテクス | 消毒および/または防腐のための有害微生物防除用組成物 |
-
1998
- 1998-10-22 US US09/176,881 patent/US6028108A/en not_active Expired - Fee Related
-
1999
- 1999-10-21 JP JP2000576825A patent/JP2002527465A/ja active Pending
- 1999-10-21 IL IL14255599A patent/IL142555A0/xx unknown
- 1999-10-21 BR BR9914725-4A patent/BR9914725A/pt not_active IP Right Cessation
- 1999-10-21 EP EP99970593A patent/EP1124536B1/de not_active Expired - Lifetime
- 1999-10-21 KR KR1020017004958A patent/KR20010080263A/ko not_active Application Discontinuation
- 1999-10-21 NZ NZ511149A patent/NZ511149A/en unknown
- 1999-10-21 CN CN99814721A patent/CN1331582A/zh active Pending
- 1999-10-21 EA EA200100459A patent/EA003771B1/ru not_active IP Right Cessation
- 1999-10-21 WO PCT/US1999/024906 patent/WO2000023050A1/en not_active Application Discontinuation
- 1999-10-21 DE DE69924133T patent/DE69924133D1/de not_active Expired - Lifetime
- 1999-10-21 CA CA002347118A patent/CA2347118A1/en not_active Abandoned
- 1999-10-21 CZ CZ20011420A patent/CZ20011420A3/cs unknown
- 1999-10-21 PL PL99347395A patent/PL347395A1/xx unknown
- 1999-10-21 AT AT99970593T patent/ATE290367T1/de not_active IP Right Cessation
- 1999-10-21 AU AU12264/00A patent/AU1226400A/en not_active Abandoned
-
2001
- 2001-04-20 NO NO20011967A patent/NO20011967L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU1226400A (en) | 2000-05-08 |
EP1124536B1 (de) | 2005-03-09 |
NO20011967L (no) | 2001-05-09 |
CZ20011420A3 (cs) | 2001-09-12 |
IL142555A0 (en) | 2002-03-10 |
WO2000023050A1 (en) | 2000-04-27 |
CA2347118A1 (en) | 2000-04-27 |
NZ511149A (en) | 2003-10-31 |
EA200100459A1 (ru) | 2001-10-22 |
NO20011967D0 (no) | 2001-04-20 |
US6028108A (en) | 2000-02-22 |
BR9914725A (pt) | 2001-08-07 |
EA003771B1 (ru) | 2003-08-28 |
JP2002527465A (ja) | 2002-08-27 |
ATE290367T1 (de) | 2005-03-15 |
EP1124536A1 (de) | 2001-08-22 |
PL347395A1 (en) | 2002-04-08 |
KR20010080263A (ko) | 2001-08-22 |
CN1331582A (zh) | 2002-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |