DK1163007T3 - TRIS-holdige propofol-formuleringer - Google Patents

TRIS-holdige propofol-formuleringer

Info

Publication number
DK1163007T3
DK1163007T3 DK00918250T DK00918250T DK1163007T3 DK 1163007 T3 DK1163007 T3 DK 1163007T3 DK 00918250 T DK00918250 T DK 00918250T DK 00918250 T DK00918250 T DK 00918250T DK 1163007 T3 DK1163007 T3 DK 1163007T3
Authority
DK
Denmark
Prior art keywords
tris
containing propofol
propofol formulations
signficant
tromethamine
Prior art date
Application number
DK00918250T
Other languages
English (en)
Inventor
Mary Mathew George
Pui-Ho Yuen
Martin A Joyce
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1163007T3 publication Critical patent/DK1163007T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK00918250T 1999-03-24 2000-03-23 TRIS-holdige propofol-formuleringer DK1163007T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/275,145 US6177477B1 (en) 1999-03-24 1999-03-24 Propofol formulation containing TRIS
PCT/US2000/007598 WO2000056364A1 (en) 1999-03-24 2000-03-23 Propofol formulation containing tris

Publications (1)

Publication Number Publication Date
DK1163007T3 true DK1163007T3 (da) 2003-04-22

Family

ID=23051046

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00918250T DK1163007T3 (da) 1999-03-24 2000-03-23 TRIS-holdige propofol-formuleringer

Country Status (10)

Country Link
US (1) US6177477B1 (da)
EP (1) EP1163007B1 (da)
AT (1) ATE231003T1 (da)
AU (1) AU3909400A (da)
BR (1) BR0009286A (da)
CA (1) CA2367093A1 (da)
DE (1) DE60001223T2 (da)
DK (1) DK1163007T3 (da)
ES (1) ES2189750T3 (da)
WO (1) WO2000056364A1 (da)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6749868B1 (en) 1993-02-22 2004-06-15 American Bioscience, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
JP4198318B2 (ja) * 1998-08-19 2008-12-17 ヤーゴテック アクチェンゲゼルシャフト プロポフォールの注射可能水性分散物
US6726919B2 (en) 2000-06-16 2004-04-27 Rtp Pharma, Inc. Injectable dispersion of propofol
US20030054042A1 (en) * 2001-09-14 2003-03-20 Elaine Liversidge Stabilization of chemical compounds using nanoparticulate formulations
JP2005517679A (ja) * 2001-12-28 2005-06-16 ギルフォード ファーマシューティカルズ インコーポレイテッド プロポフォールの水溶性プロドラッグの水ベースの薬学的製剤
IL162862A0 (en) * 2002-01-25 2005-11-20 Theravance Inc Short-acting sedative hypnotic agents for anesthesia and sedation
US20080220075A1 (en) * 2002-03-20 2008-09-11 Elan Pharma International Ltd. Nanoparticulate compositions of angiogenesis inhibitors
DE60309300T3 (de) * 2002-03-20 2011-02-24 Elan Pharma International Ltd. Nanopartikelzusammensetzungen von angiogeneseinhibitoren
KR100459025B1 (ko) * 2002-05-02 2004-12-03 (주) 에프디엘 프로포폴을 함유하는 신규한 주사제용 조성물
AU2003222491A1 (en) * 2002-05-02 2003-12-31 Fdl, Inc. Novel parenteral composition comprising propofol
CN1708270A (zh) * 2002-10-29 2005-12-14 转化医药公司 丙泊酚与半胱氨酸
TR200502189T1 (tr) * 2002-12-09 2007-01-22 American Bioscience, Inc. Kompozisyonlar ve farmakolojik etken maddelerin aktarımı için yöntemler.
US20040225022A1 (en) * 2003-05-09 2004-11-11 Desai Neil P. Propofol formulation containing reduced oil and surfactants
US8476010B2 (en) 2003-07-10 2013-07-02 App Pharmaceuticals Llc Propofol formulations with non-reactive container closures
DE602004023509D1 (de) * 2003-07-23 2009-11-19 Theravance Inc Pharmazeutische zusammensetzungen eines kurzwirkenden sedativen hypnosemittels
US8546453B2 (en) * 2003-08-14 2013-10-01 Rensheng Zhang Propofol compositions and methods for reducing pain associated with propofol injection
US20070293586A1 (en) * 2005-02-03 2007-12-20 Suresh Dixit Novel propofol composition comprising ascorbic acid or pharmaceutically acceptable salts thereof
CN100358513C (zh) * 2005-04-07 2008-01-02 常州市第四制药厂有限公司 一种丙泊酚注射液的制备工艺
US20090131538A1 (en) * 2005-05-27 2009-05-21 Taro Pharmaceuticals North America, Inc. c/o Taro Pharmaceuticals U.S.A., Inc. Novel propofol composition comprising a pharmaceutically acceptable salt of formaldehyde sulfoxylate
CN101291658B (zh) * 2005-08-31 2014-04-16 阿布拉科斯生物科学有限公司 用于制备稳定性增加的水难溶性药物的组合物和方法
TWI417114B (zh) 2005-08-31 2013-12-01 Abraxis Bioscience Llc 具有增強穩定性之弱水溶性藥物之組合物及其製備方法
WO2010082092A1 (en) 2009-01-13 2010-07-22 Claris Lifesciences Limited Propofol based anesthetic with preservative
CN102869345B (zh) 2010-03-17 2015-02-11 诺瓦利克有限责任公司 用于治疗眼内压增高的药物组合物
EP2444063A1 (en) 2010-10-20 2012-04-25 Novaliq GmbH Liquid pharmaceutical compositions for the delivery of active ingredients
EP2462921A1 (en) 2010-11-11 2012-06-13 Novaliq GmbH Liquid pharmaceutical compositions for the treatment of a posterior eye disease
PL2661280T3 (pl) * 2011-01-04 2019-05-31 Novaliq Gmbh Emulsje typu olej w wodzie zawierające semifluorowane alkany
CA2834862C (en) 2011-05-25 2019-12-17 Novaliq Gmbh Pharmaceutical composition for administration to nails
PL3192501T3 (pl) 2011-05-25 2020-11-02 Novaliq Gmbh Kompozycja farmaceutyczna do miejscowego stosowania oparta na semifluorowanych alkanach
KR101989648B1 (ko) 2012-01-23 2019-06-14 노바리크 게엠베하 부분불소화 알칸에 기초한 안정화된 단백질 조성물
WO2013172999A1 (en) 2012-05-16 2013-11-21 Mewa Singh Pharmaceutical compositions for the delivery of substantially water-insoluble drugs
EP2884964A4 (en) * 2012-08-16 2016-01-06 Emcure Pharmaceuticals Ltd PHARMACEUTICAL COMPOSITION OF PROPOFOL
ES2965828T3 (es) 2012-09-12 2024-04-17 Novaliq Gmbh Composiciones de alcano semifluorado
CA2883002C (en) 2012-09-12 2019-05-21 Novaliq Gmbh Compositions comprising mixtures of semifluorinated alkanes
US10273298B2 (en) 2013-07-23 2019-04-30 Novaliq Gmbh Stabilized antibody compositions
WO2015054448A1 (en) * 2013-10-11 2015-04-16 University Of Florida Research Foundation, Inc. Method of manufacturing stable emulsions and compositions containing the same
JP6392883B2 (ja) * 2014-09-25 2018-09-19 富士フイルム株式会社 プロポフォール含有水中油型エマルション組成物及びその製造方法
WO2017017693A1 (en) 2015-07-24 2017-02-02 Neon Laboratories Limited Stabilized injectable emulsion of propofol and ketamine
US11622937B2 (en) 2015-08-20 2023-04-11 Mewa Singh Polyphenolic polymer to make water-insoluble molecules become water-soluble
CN110403923B (zh) 2015-09-30 2021-09-21 诺瓦利克有限责任公司 半氟化化合物和其组合物
EP3722274B1 (en) 2015-09-30 2023-06-07 Novaliq GmbH 2-perfluorobutyl pentane for ophthalmic administration
DK3442480T3 (da) 2016-06-23 2020-01-13 Novaliq Gmbh Fremgangsmåde til topisk indgivelse
ES2969758T3 (es) 2016-09-22 2024-05-22 Novaliq Gmbh Composiciones farmacéuticas para usar en la terapia de la blefaritis
CN109906085B (zh) 2016-09-23 2024-03-08 诺瓦利克有限责任公司 含有环孢素的眼用组合物
AU2018253944B2 (en) 2017-04-21 2022-09-15 Dermaliq Therapeutics, Inc. Iodine compositions
EP3621601A1 (en) 2017-05-12 2020-03-18 Novaliq GmbH Pharmaceutical compositions comprosing semifluorinated alkanes for the treatment of contact lense-related conditions
US11723861B2 (en) 2017-09-27 2023-08-15 Novaliq Gmbh Ophthalmic compositions comprising latanoprost for use in the treatment of ocular diseases
US11896559B2 (en) 2017-10-04 2024-02-13 Novaliq Gmbh Opthalmic compositions comprising F6H8
SG11202007858VA (en) 2018-03-02 2020-09-29 Novaliq Gmbh Pharmaceutical compositions comprising nebivolol
SG11202102820VA (en) 2018-10-12 2021-04-29 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472793A (en) * 1974-03-28 1977-05-04 Ici Ltd Pharmaceutical compositions
US4060639A (en) * 1976-05-14 1977-11-29 Merck & Co., Inc. Broad spectrum antibacterial compositions containing tris-(hydroxymethyl)-aminoethane and dicycloaliphatic-alkyl polyamines
DE4028957C2 (de) * 1990-09-12 1994-05-11 Oliver Bock Therapeutikum für den Mundbereich
US5504113A (en) * 1994-03-02 1996-04-02 Allergan, Inc. Enhancement of benzalkonium chloride preservative activity in formulations containing an incompatible drug
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
US5633240A (en) * 1994-09-01 1997-05-27 Academic Pharmaceuticals Parenteral solutions containing metolazone
US5637625A (en) * 1996-03-19 1997-06-10 Research Triangle Pharmaceuticals Ltd. Propofol microdroplet formulations
CH692322A5 (it) * 1997-05-26 2002-05-15 Westy Ag Formulazione iniettabile limpida di Propofol.
US5962536A (en) * 1998-07-31 1999-10-05 Komer; Gene Injectable propofol formulations
US6028108A (en) * 1998-10-22 2000-02-22 America Home Products Corporation Propofol composition comprising pentetate

Also Published As

Publication number Publication date
BR0009286A (pt) 2002-01-22
EP1163007A1 (en) 2001-12-19
AU3909400A (en) 2000-10-09
WO2000056364A1 (en) 2000-09-28
DE60001223D1 (de) 2003-02-20
DE60001223T2 (de) 2004-01-22
CA2367093A1 (en) 2000-09-28
US6177477B1 (en) 2001-01-23
EP1163007B1 (en) 2003-01-15
ES2189750T3 (es) 2003-07-16
ATE231003T1 (de) 2003-02-15

Similar Documents

Publication Publication Date Title
DK1163007T3 (da) TRIS-holdige propofol-formuleringer
DE69924133D1 (de) Diethylentriaminpentaessigsäure enthaltende propofol-zusammensetzung
CA2319810A1 (en) Propofol composition containing sulfite
EP1238677A3 (en) Parenteral fat emulsions comprising edetate as preservative
MXPA02008097A (es) Formulacion de propol con inhibicion microbiana mejorada.
MY125921A (en) Compositions containing organic compounds
WO1998058629A3 (en) Preparation of pharmaceutical compositions
SE7703592L (sv) Anthelmintikum
ATE427925T1 (de) Phenoxycarbonsaureverbindungen und zusammensetzungen zur verabreichung aktiver wirkstoffe
TR199801541A2 (xx) N,N-Dietil-m-Toluamid'in (DEET) Anti-Parazit i�levi
FI964285A0 (fi) Taksaanien luokkaan kuuluviin johdannaisiin perustuvat farmaseuttiset valmisteet
KR910021375A (ko) 4-(디-n-프로필)아미노-6-아미노카보닐-1,3,4,5-테트라하이드로벤즈[cd]인돌의 결정형 염
ES2037742T3 (es) Procedimiento de obtencion de una composicion para administracion intravenosa.
WO2004100935A3 (en) Propofol formulation containing reduced oil and surfactants
BRPI9916820B8 (pt) composição compreendendo 9[2[[bis[(pivaloilóxi)metil]fosfono]metóxi]etil]adenina, comprimido ou cápsula e método
SE9403389D0 (sv) Pharmaceutical composition containing derivattves of sex hormones
NZ220800A (en) Tetrahydrobenzothiazoles and pharmaceutical compositions
ATE90095T1 (de) Optisch aktive produkte von 20,21dinoreburnamenin-derivaten,verfahren zur herstellung, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammenstellungen.
AU5284999A (en) New injectable formulations containing ramoplanin
ES2171749T3 (es) Composiciones farmaceuticas que contienen inhibidores de la agregacion de plaquetas.
AR004223A1 (es) Composiciones para inhibir la agregacion de plaquetas y el uso de las mismas en la manufactura de un medicamento.
BG96101A (bg) Авермектинови производни, по-специално с-076 съединения,и метод за получаването им