DE69919325T3 - Spektrometer mit gepulster Ionenquelle, Kopplungsvorrichtung zur Dämpfung der Ionenbewegung, und Methode zur Verwendung derselben - Google Patents

Spektrometer mit gepulster Ionenquelle, Kopplungsvorrichtung zur Dämpfung der Ionenbewegung, und Methode zur Verwendung derselben Download PDF

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Publication number
DE69919325T3
DE69919325T3 DE69919325.7T DE69919325T DE69919325T3 DE 69919325 T3 DE69919325 T3 DE 69919325T3 DE 69919325 T DE69919325 T DE 69919325T DE 69919325 T3 DE69919325 T3 DE 69919325T3
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DE
Germany
Prior art keywords
ion
ions
mass spectrometer
ion source
mass
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69919325.7T
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German (de)
English (en)
Other versions
DE69919325D1 (de
DE69919325T2 (de
Inventor
Andrew Krutchinsky
Alexandre Loboda
Victor Spicer
Erich ENS
Kenneth Standing
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University of Manitoba
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University of Manitoba
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4162020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69919325(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of Manitoba filed Critical University of Manitoba
Publication of DE69919325D1 publication Critical patent/DE69919325D1/de
Application granted granted Critical
Publication of DE69919325T2 publication Critical patent/DE69919325T2/de
Publication of DE69919325T3 publication Critical patent/DE69919325T3/de
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Electron Sources, Ion Sources (AREA)
DE69919325.7T 1998-01-23 1999-01-25 Spektrometer mit gepulster Ionenquelle, Kopplungsvorrichtung zur Dämpfung der Ionenbewegung, und Methode zur Verwendung derselben Expired - Lifetime DE69919325T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA2227806 1998-01-23
CA002227806A CA2227806C (en) 1998-01-23 1998-01-23 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
EP99900849.3A EP1050061B2 (en) 1998-01-23 1999-01-25 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
PCT/CA1999/000034 WO1999038185A2 (en) 1998-01-23 1999-01-25 Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use

Publications (3)

Publication Number Publication Date
DE69919325D1 DE69919325D1 (de) 2004-09-16
DE69919325T2 DE69919325T2 (de) 2005-02-17
DE69919325T3 true DE69919325T3 (de) 2017-03-02

Family

ID=4162020

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69919325.7T Expired - Lifetime DE69919325T3 (de) 1998-01-23 1999-01-25 Spektrometer mit gepulster Ionenquelle, Kopplungsvorrichtung zur Dämpfung der Ionenbewegung, und Methode zur Verwendung derselben
DE1050061T Pending DE1050061T1 (de) 1998-01-23 1999-01-25 Spektrometer mit gepulster ionenquelle, kopplungsvorrichting zur dämpfung der ionenbewegung, und methode zur verwendung derselben

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1050061T Pending DE1050061T1 (de) 1998-01-23 1999-01-25 Spektrometer mit gepulster ionenquelle, kopplungsvorrichting zur dämpfung der ionenbewegung, und methode zur verwendung derselben

Country Status (8)

Country Link
EP (1) EP1050061B2 (cg-RX-API-DMAC7.html)
JP (1) JP4331398B2 (cg-RX-API-DMAC7.html)
AT (1) ATE273561T2 (cg-RX-API-DMAC7.html)
AU (1) AU745866B2 (cg-RX-API-DMAC7.html)
CA (1) CA2227806C (cg-RX-API-DMAC7.html)
DE (2) DE69919325T3 (cg-RX-API-DMAC7.html)
DK (1) DK1050061T4 (cg-RX-API-DMAC7.html)
WO (1) WO1999038185A2 (cg-RX-API-DMAC7.html)

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US5965884A (en) * 1998-06-04 1999-10-12 The Regents Of The University Of California Atmospheric pressure matrix assisted laser desorption
US6849847B1 (en) 1998-06-12 2005-02-01 Agilent Technologies, Inc. Ambient pressure matrix-assisted laser desorption ionization (MALDI) apparatus and method of analysis
GB9820210D0 (en) * 1998-09-16 1998-11-11 Vg Elemental Limited Means for removing unwanted ions from an ion transport system and mass spectrometer
US6504150B1 (en) 1999-06-11 2003-01-07 Perseptive Biosystems, Inc. Method and apparatus for determining molecular weight of labile molecules
DE10010204A1 (de) 2000-03-02 2001-09-13 Bruker Daltonik Gmbh Konditionierung eines Ionenstrahls für den Einschuss in ein Flugzeitmassenspektrometer
DE10010902A1 (de) 2000-03-07 2001-09-20 Bruker Daltonik Gmbh Tandem-Massenspektrometer aus zwei Quadrupolfiltern
US6586727B2 (en) * 2000-06-09 2003-07-01 Micromass Limited Methods and apparatus for mass spectrometry
CA2340150C (en) * 2000-06-09 2005-11-22 Micromass Limited Methods and apparatus for mass spectrometry
US6642514B2 (en) 2000-11-29 2003-11-04 Micromass Limited Mass spectrometers and methods of mass spectrometry
US6891153B2 (en) 2000-11-29 2005-05-10 Micromass Uk Limited Mass spectrometers and methods of mass spectrometry
US20020115056A1 (en) 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
US6617577B2 (en) * 2001-04-16 2003-09-09 The Rockefeller University Method and system for mass spectroscopy
EP1430508A1 (en) 2001-09-17 2004-06-23 MDS Inc., doing business as MDS Sciex Method and apparatus for cooling and focusing ions
AU2002349241A1 (en) 2001-12-14 2003-06-30 Mds Inc., D.B.A. Mds Sciex Method of chemical of ionization at reduced pressures
AU2003220320A1 (en) 2002-03-21 2003-10-08 Thermo Finnigan Llc Ionization apparatus and method for mass spectrometer system
US7388194B2 (en) 2002-03-28 2008-06-17 Mds Sciex Inc. Method and system for high-throughput quantitation using laser desorption and multiple-reaction-monitoring
AU2003230093A1 (en) * 2002-03-28 2003-10-13 Mds Sciex Method and system for high-throughput quantitation of small molecules using laser desorption and multiple-reaction-monitoring
US7405397B2 (en) 2002-03-28 2008-07-29 Mds Sciex Inc. Laser desorption ion source with ion guide coupling for ion mass spectroscopy
GB0210930D0 (en) 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
US6977371B2 (en) 2003-06-10 2005-12-20 Micromass Uk Limited Mass spectrometer
DE102004025841B4 (de) * 2004-05-24 2015-07-09 Bruker Daltonik Gmbh Verfahren und Vorrichtung zur massenspektroskopischen Untersuchung von Analyten
GB0420408D0 (en) * 2004-09-14 2004-10-20 Micromass Ltd Mass spectrometer
DE102004051785B4 (de) 2004-10-25 2008-04-24 Bruker Daltonik Gmbh Proteinprofile mit Luft-MALDI
EP1955077B1 (en) 2005-12-02 2012-06-13 Sirtris Pharmaceuticals, Inc. Mass spectrometry assays for acetyltransferase/deacetylase activity
CA2645159A1 (en) 2006-03-10 2008-06-26 Michael S. Urdea Multiplex protein fractionation
DE102007043456B4 (de) 2007-07-31 2012-02-09 Bruker Daltonik Gmbh Matrixunterstützte Laserdesorption hoher Ionisierungsausbeute
KR102744729B1 (ko) * 2018-02-13 2024-12-18 바이오메리욱스, 인코포레이티드. 기기에서 하전 입자 생성을 확인하기 위한 방법들 및 관련 기기들
US12205807B2 (en) 2020-04-01 2025-01-21 Mstm, Llc Multi-mode ionization apparatus and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535235A (en) † 1983-05-06 1985-08-13 Finnigan Corporation Apparatus and method for injection of ions into an ion cyclotron resonance cell
DE3650304T2 (de) † 1985-05-24 1995-10-12 Finnigan Corp Betriebsverfahren für eine Ionenfalle.
WO1989006044A1 (en) † 1987-12-24 1989-06-29 Unisearch Limited Mass spectrometer
CA1307859C (en) † 1988-12-12 1992-09-22 Donald James Douglas Mass spectrometer and method with improved ion transmission
DE4202123C2 (de) † 1992-01-27 1995-04-06 Bruker Franzen Analytik Gmbh Vorrichtung für die massenspektrometrische Untersuchung schneller organischer Ionen
US5689111A (en) * 1995-08-10 1997-11-18 Analytica Of Branford, Inc. Ion storage time-of-flight mass spectrometer
DE19511333C1 (de) * 1995-03-28 1996-08-08 Bruker Franzen Analytik Gmbh Verfahren und Vorrichtung für orthogonalen Einschuß von Ionen in ein Flugzeit-Massenspektrometer
DE19629134C1 (de) † 1996-07-19 1997-12-11 Bruker Franzen Analytik Gmbh Vorrichtung zur Überführung von Ionen und mit dieser durchgeführtes Meßverfahren
CA2312806A1 (en) * 1997-12-05 1999-06-17 University Of British Columbia Method of analyzing ions in an apparatus including a time of flight mass spectrometer and a linear ion trap

Also Published As

Publication number Publication date
CA2227806C (en) 2006-07-18
DK1050061T4 (en) 2017-01-23
AU2042899A (en) 1999-08-09
DK1050061T3 (da) 2004-11-22
ATE273561T2 (de) 2004-08-15
DE1050061T1 (de) 2001-06-07
DE69919325D1 (de) 2004-09-16
WO1999038185A2 (en) 1999-07-29
JP2002502084A (ja) 2002-01-22
AU745866B2 (en) 2002-04-11
JP4331398B2 (ja) 2009-09-16
WO1999038185A3 (en) 1999-10-21
EP1050061A2 (en) 2000-11-08
EP1050061B2 (en) 2016-10-19
CA2227806A1 (en) 1999-07-23
EP1050061B1 (en) 2004-08-11
DE69919325T2 (de) 2005-02-17

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