DE69913242D1 - Peptidanaloge des Glucagon-ähnlichen-Peptids-1 (7-37), deren Herstellung und pharmazeutische Zusammensetzungen - Google Patents

Peptidanaloge des Glucagon-ähnlichen-Peptids-1 (7-37), deren Herstellung und pharmazeutische Zusammensetzungen

Info

Publication number
DE69913242D1
DE69913242D1 DE69913242T DE69913242T DE69913242D1 DE 69913242 D1 DE69913242 D1 DE 69913242D1 DE 69913242 T DE69913242 T DE 69913242T DE 69913242 T DE69913242 T DE 69913242T DE 69913242 D1 DE69913242 D1 DE 69913242D1
Authority
DE
Germany
Prior art keywords
peptide
glucagon
preparation
pharmaceutical compositions
heteroarylcarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69913242T
Other languages
English (en)
Other versions
DE69913242T2 (de
Inventor
Bernard Calas
Gerard Grassy
Alain Chavanieu
De Menthiere Cyril Sarrauste
Pierre Renard
Bruno Pfeiffer
Dominique Manechez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Publication of DE69913242D1 publication Critical patent/DE69913242D1/de
Application granted granted Critical
Publication of DE69913242T2 publication Critical patent/DE69913242T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE69913242T 1998-04-10 1999-03-12 Peptidanaloge des Glucagon-ähnlichen-Peptids-1 (7-37), deren Herstellung und pharmazeutische Zusammensetzungen Expired - Fee Related DE69913242T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9804559A FR2777283B1 (fr) 1998-04-10 1998-04-10 Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR9804559 1998-04-10

Publications (2)

Publication Number Publication Date
DE69913242D1 true DE69913242D1 (de) 2004-01-15
DE69913242T2 DE69913242T2 (de) 2004-09-09

Family

ID=9525150

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69913242T Expired - Fee Related DE69913242T2 (de) 1998-04-10 1999-03-12 Peptidanaloge des Glucagon-ähnlichen-Peptids-1 (7-37), deren Herstellung und pharmazeutische Zusammensetzungen

Country Status (19)

Country Link
US (1) US6620910B1 (de)
EP (1) EP0955314B1 (de)
JP (1) JP3787242B2 (de)
CN (1) CN1305897C (de)
AT (1) ATE255596T1 (de)
AU (1) AU761652B2 (de)
BR (1) BR9902014A (de)
CA (1) CA2263059A1 (de)
DE (1) DE69913242T2 (de)
DK (1) DK0955314T3 (de)
ES (1) ES2212485T3 (de)
FR (1) FR2777283B1 (de)
HK (1) HK1022320A1 (de)
HU (1) HUP9900604A3 (de)
NO (1) NO323137B1 (de)
NZ (1) NZ334379A (de)
PL (1) PL331960A1 (de)
PT (1) PT955314E (de)
ZA (1) ZA992035B (de)

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US7186683B2 (en) 2000-09-18 2007-03-06 Sanos Bioscience A/S Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders
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WO2003057235A2 (en) 2002-01-10 2003-07-17 Imperial College Innovations Ltd Modification of feeding behavior
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
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CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
US7872124B2 (en) 2004-12-21 2011-01-18 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
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GB0511986D0 (en) * 2005-06-13 2005-07-20 Imp College Innovations Ltd Novel compounds and their effects on feeding behaviour
DK1942898T4 (da) 2005-09-14 2014-06-02 Takeda Pharmaceutical Dipeptidylpeptidase-inhibitorer til behandling af diabetes
DK1937219T3 (en) 2005-09-14 2016-02-15 Mannkind Corp A method for drug formulation based on increasing the affinity of the crystalline surfaces of the microparticle of active principles
KR101368988B1 (ko) 2005-09-16 2014-02-28 다케다 야쿠힌 고교 가부시키가이샤 디펩티딜 펩티다제 억제제
WO2007051987A1 (en) * 2005-11-01 2007-05-10 Activotec Spp Limited Insulinotropic compounds and uses thereof
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CN1982336B (zh) * 2006-03-03 2011-01-12 华东师范大学 一种人胰高血糖素样肽-1衍生物及其制备和应用
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EP2954893A1 (de) * 2007-10-24 2015-12-16 MannKind Corporation Eine inhalierbare, trockenpulver-formulierung, enthaltend glp-1 zur verwendung in der behandlung von hyperglykämie und diabetes
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
KR101933816B1 (ko) 2008-06-13 2019-03-29 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
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TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CN101463081B (zh) * 2009-01-12 2012-07-04 华东师范大学 一种glp-1衍生物
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
EP2413955A4 (de) 2009-04-01 2012-12-26 Amylin Pharmaceuticals Inc N-terminale konformationseingeschränkte glp-1-rezeptoragonistenverbindungen
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
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KR20130101005A (ko) * 2010-07-28 2013-09-12 아밀린 파마슈티칼스, 엘엘씨. 안정화된 영역을 갖는 glp-1 수용체 효능제 화합물
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
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CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CN104185639B (zh) * 2012-03-01 2018-06-19 诺和诺德股份有限公司 Glp-1前体药物
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Also Published As

Publication number Publication date
CA2263059A1 (fr) 1999-10-10
ZA992035B (en) 1999-09-27
NO991199D0 (no) 1999-03-11
HK1022320A1 (en) 2000-08-04
EP0955314A3 (de) 2000-03-29
ATE255596T1 (de) 2003-12-15
AU2368899A (en) 1999-10-21
FR2777283B1 (fr) 2000-11-24
JPH11310597A (ja) 1999-11-09
CN1305897C (zh) 2007-03-21
PL331960A1 (en) 1999-10-11
PT955314E (pt) 2004-03-31
FR2777283A1 (fr) 1999-10-15
NZ334379A (en) 1999-10-28
DK0955314T3 (da) 2004-04-13
HUP9900604A2 (hu) 1999-09-28
ES2212485T3 (es) 2004-07-16
JP3787242B2 (ja) 2006-06-21
HU9900604D0 (en) 1999-05-28
US6620910B1 (en) 2003-09-16
CN1232038A (zh) 1999-10-20
NO323137B1 (no) 2007-01-08
EP0955314B1 (de) 2003-12-03
EP0955314A2 (de) 1999-11-10
HUP9900604A3 (en) 2001-01-29
AU761652B2 (en) 2003-06-05
BR9902014A (pt) 2000-05-02
NO991199L (no) 1999-10-11
DE69913242T2 (de) 2004-09-09

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