DE69910580D1 - Von der telomerase abgeleitete antigene peptide - Google Patents
Von der telomerase abgeleitete antigene peptideInfo
- Publication number
- DE69910580D1 DE69910580D1 DE69910580T DE69910580T DE69910580D1 DE 69910580 D1 DE69910580 D1 DE 69910580D1 DE 69910580 T DE69910580 T DE 69910580T DE 69910580 T DE69910580 T DE 69910580T DE 69910580 D1 DE69910580 D1 DE 69910580D1
- Authority
- DE
- Germany
- Prior art keywords
- telomerase
- peptides derived
- antigenic peptides
- antigenic
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108010017842 Telomerase Proteins 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001154—Enzymes
- A61K39/001157—Telomerase or TERT [telomerase reverse transcriptase]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO983141 | 1998-07-08 | ||
NO19983141A NO313834B1 (no) | 1998-07-08 | 1998-07-08 | Telomeraseprotein eller -peptider, nukleinsyresekvenser som koder for disse, farmasöytiske sammensetninger inneholdende disseog fremgangsmÕter for Õ fremstille slike farmasöytiskesammensetninger til profylakse mot og behandling av kreft, samt |
PCT/NO1999/000220 WO2000002581A1 (en) | 1998-07-08 | 1999-06-30 | Antigenic peptides derived from telomerase |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69910580D1 true DE69910580D1 (de) | 2003-09-25 |
DE69910580T2 DE69910580T2 (de) | 2004-06-24 |
DE69910580T3 DE69910580T3 (de) | 2009-11-26 |
Family
ID=19902234
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69942072T Expired - Lifetime DE69942072D1 (de) | 1998-07-08 | 1999-06-30 | Von der Telomerase abgeleitete antigene Peptide |
DE1999610580 Expired - Lifetime DE69910580T3 (de) | 1998-07-08 | 1999-06-30 | Von der telomerase abgeleitete antigene peptide |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69942072T Expired - Lifetime DE69942072D1 (de) | 1998-07-08 | 1999-06-30 | Von der Telomerase abgeleitete antigene Peptide |
Country Status (20)
Country | Link |
---|---|
US (2) | US7030211B1 (de) |
EP (4) | EP1362597B2 (de) |
JP (2) | JP4618657B2 (de) |
CN (1) | CN100376290C (de) |
AR (2) | AR020601A1 (de) |
AT (2) | ATE247484T1 (de) |
AU (1) | AU756094B2 (de) |
CA (2) | CA2748996A1 (de) |
CY (1) | CY1109978T1 (de) |
CZ (1) | CZ303215B6 (de) |
DE (2) | DE69942072D1 (de) |
DK (2) | DK1362597T3 (de) |
ES (2) | ES2200526T5 (de) |
HK (1) | HK1039068B (de) |
HU (1) | HU230007B1 (de) |
NO (1) | NO313834B1 (de) |
PL (1) | PL203815B1 (de) |
PT (2) | PT1093381E (de) |
TW (1) | TWI261617B (de) |
WO (1) | WO2000002581A1 (de) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
KR20000048820A (ko) | 1996-10-01 | 2000-07-25 | 게론 코포레이션 | 텔로머라제 역전사 효소 |
US6475789B1 (en) | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
US7413864B2 (en) | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
US7622549B2 (en) | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
AU3456099A (en) | 1998-03-31 | 1999-10-18 | Geron Corporation | Methods and compositions for eliciting an immune response to a telomerase antigen |
US7402307B2 (en) | 1998-03-31 | 2008-07-22 | Geron Corporation | Method for identifying and killing cancer cells |
US7851591B1 (en) | 1998-10-29 | 2010-12-14 | Dana Farber Cancer Institute, Inc. | Cancer immunotherapy and diagnosis using universal tumor associated antigens, including hTERT |
EP1171612A2 (de) * | 1999-04-09 | 2002-01-16 | Biomira, Inc. | Telomerase-spezifisches krebsimpfstoff |
EP1257284A4 (de) * | 2000-02-15 | 2005-12-21 | Univ California | Ein universelles vakzin und ein verfahren zur behandlung von krebs mit telomerase reverse transkriptase |
AU2001241533A1 (en) * | 2000-02-15 | 2001-08-27 | The Regents Of The University Of California | A universal vaccine and method for treating cancer employing telomerase reverse transcriptase |
FR2812087B1 (fr) * | 2000-07-21 | 2007-05-11 | Inst Nat Sante Rech Med | Procede de criblage de peptides utilisables en immunotherapie |
GB0031430D0 (en) * | 2000-12-22 | 2001-02-07 | Norsk Hydro As | Polypeptides |
GB0105238D0 (en) * | 2001-03-02 | 2001-04-18 | Norsk Hydro As | Vaccines |
GB0112342D0 (en) * | 2001-05-21 | 2001-07-11 | Norsk Hydro As | Polypeptides |
WO2004111075A2 (en) * | 2003-03-05 | 2004-12-23 | Dendreon Corporation | Alternative reading frame polypeptides for treatment |
EP1748067A1 (de) * | 2005-07-29 | 2007-01-31 | Institut Pasteur | Polynukleotide, die für MHC Klasse I-beschränkte Epitope der hTERT, Analoge und Polyepitope kodieren |
US10767167B2 (en) | 2005-07-29 | 2020-09-08 | Institut Pasteur | Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes |
JP2009523817A (ja) * | 2006-01-19 | 2009-06-25 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ヒトテロメラーゼ逆転写酵素ペプチド |
US9732131B2 (en) | 2006-02-27 | 2017-08-15 | Calviri, Inc. | Identification and use of novopeptides for the treatment of cancer |
WO2008010010A1 (en) * | 2006-07-12 | 2008-01-24 | Vaxon Biotech | Identification, optimization and use of cryptic hla-b7 epitopes for immunotherapy |
EP1887084A1 (de) * | 2006-08-10 | 2008-02-13 | International Investment and Patents SA | Plasmide mit immunologischer Wirkung |
JP5207354B2 (ja) * | 2008-03-12 | 2013-06-12 | 独立行政法人産業技術総合研究所 | 転写抑制ペプチド及びその遺伝子 |
JP5787752B2 (ja) * | 2008-06-16 | 2015-09-30 | メディオラヌム・ファルマチェウティチ・ソチエタ・ペル・アツィオーニ | 抗腫瘍免疫療法 |
WO2010037395A2 (en) * | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
GB0821616D0 (en) | 2008-11-26 | 2008-12-31 | Lytix Biopharma As | Compounds |
US11673914B2 (en) | 2009-11-10 | 2023-06-13 | Allegro Pharmaceuticals, LLC | Peptide therapies for reduction of macular thickening |
MX346362B (es) | 2009-11-10 | 2017-03-15 | Allegro Pharmaceuticals Inc * | Composiciones y metodos para inhibir la adhesion celular o dirigir agentes de diagnostico o terapeuticos a sitios de enlace rgd. |
RU2581800C2 (ru) * | 2010-02-16 | 2016-04-20 | Ультимовакс Ас | Полипептиды |
FR2960542B1 (fr) | 2010-05-27 | 2012-08-17 | Esther Suzy Arlette Fellous | Peptide en tant que medicament, en particulier pour le traitement du cancer |
ES2820855T3 (es) * | 2011-05-09 | 2021-04-22 | Allegro Pharmaceuticals Llc | Antagonistas del receptor de integrina y sus métodos de uso |
EP3333180B1 (de) * | 2012-05-11 | 2019-08-21 | KAEL-GemVax Co.,Ltd | Antientzündliche peptide und zusammensetzungen die diese enthaltend |
CN108949717B (zh) * | 2012-05-11 | 2023-06-20 | 珍白斯凯尔有限公司 | 抗炎性肽及包含其的组合物 |
WO2013169060A1 (ko) * | 2012-05-11 | 2013-11-14 | 주식회사 카엘젬백스 | 패혈증 예방 또는 치료용 조성물 |
US10967000B2 (en) * | 2012-07-11 | 2021-04-06 | Gemvax & Kael Co., Ltd. | Cell-penetrating peptide, conjugate comprising same and composition comprising same |
US20150125438A1 (en) * | 2012-07-20 | 2015-05-07 | Sang Jae Kim | Anti-Inflammatory Peptides and Composition Comprising the Same |
KR102201430B1 (ko) * | 2012-09-19 | 2021-01-12 | 주식회사 젬백스앤카엘 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
KR102038487B1 (ko) | 2012-09-19 | 2019-10-30 | 주식회사 젬백스앤카엘 | 텔로머라제 펩티드를 포함하는 항균 또는 항진균용 조성물 |
JP6517692B2 (ja) * | 2012-09-19 | 2019-05-22 | ジェムバックス アンド カエル カンパニー,リミティド | 細胞透過性ペプチド、それを含んだコンジュゲート、及びそれを含んだ組成物 |
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CN102875657B (zh) * | 2012-10-22 | 2014-04-09 | 南京工业大学 | 一种制备端粒酶多肽疫苗的方法 |
KR102106756B1 (ko) | 2012-12-13 | 2020-05-06 | 주식회사 젬백스앤카엘 | 자외선에 의한 피부 손상 예방 또는 치료용 조성물 |
KR102093093B1 (ko) | 2012-12-13 | 2020-03-25 | 주식회사 젬백스앤카엘 | 피부 노화 개선용 조성물 |
ES2716870T3 (es) * | 2013-04-19 | 2019-06-17 | Gemvax & Kael Co Ltd | Composición para el tratamiento y prevención de lesión isquémica |
TWI634210B (zh) * | 2013-05-03 | 2018-09-01 | 傑姆維克斯&凱爾有限公司 | 抑制熱休克蛋白質表現之胜肽及包含其之組成物 |
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KR102166545B1 (ko) * | 2013-06-21 | 2020-10-16 | 주식회사 젬백스앤카엘 | 호르몬 분비 조절제, 이를 포함하는 조성물, 및 이를 사용한 호르몬 분비 조절 방법 |
JP6574175B2 (ja) * | 2013-07-12 | 2019-09-11 | ジェムバックス アンド カエル カンパニー,リミティド | 細胞透過性ペプチド、及びそれを含むコンジュゲート |
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KR102106757B1 (ko) * | 2013-11-29 | 2020-05-06 | 주식회사 젬백스앤카엘 | 난소 동결 보존용 펩티드 및 이를 포함하는 조성물 |
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KR102166549B1 (ko) | 2014-01-10 | 2020-10-16 | 주식회사 젬백스앤카엘 | 혈뇌장벽 투과성 펩티드 및 이를 포함하는 컨쥬게이트 |
KR101503341B1 (ko) | 2014-03-12 | 2015-03-18 | 국립암센터 | 자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법 |
CN106456697B (zh) | 2014-04-11 | 2019-12-17 | 珍白斯凯尔有限公司 | 具有纤维化抑制活性的肽和含有其的组合物 |
WO2015170790A1 (ko) * | 2014-05-09 | 2015-11-12 | 주식회사 카엘젬백스 | 허혈성 손상 치료 및 예방용 조성물 |
ES2962532T3 (es) | 2014-04-30 | 2024-03-19 | Gemvax & Kael Co Ltd | Composición para el trasplante de órganos, tejidos o células, kit y procedimiento de trasplante |
CN105622722B (zh) * | 2014-05-29 | 2019-12-24 | 北京东方略生物医药科技股份有限公司 | 一种治疗癌症的肽变体xa3及其应用 |
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EP3263122B1 (de) * | 2015-02-27 | 2020-05-06 | Gemvax & Kael Co., Ltd. | Peptid zur verhinderung von hörverlust und zusammensetzung damit |
JP7000161B2 (ja) | 2015-05-26 | 2022-01-19 | ジェムバックス アンド カエル カンパニー,リミティド | 新規ペプチド及びこれを含む組成物 |
US11015179B2 (en) | 2015-07-02 | 2021-05-25 | Gemvax & Kael Co., Ltd. | Peptide having anti-viral effect and composition containing same |
KR20170054310A (ko) * | 2015-11-09 | 2017-05-17 | 주식회사 젬백스앤카엘 | 텔로머라제 유래 펩티드를 포함하는 수지상세포 치료제 및 면역 치료제, 및 이를 사용하는 치료방법 |
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WO2018145020A1 (en) | 2017-02-03 | 2018-08-09 | The Medical College Of Wisconsin, Inc. | Kras peptide vaccine compositions and method of use |
CN110996970A (zh) | 2017-06-02 | 2020-04-10 | 亚利桑那州立大学董事会 | 创建个性化癌症疫苗的方法 |
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WO2021067550A1 (en) | 2019-10-02 | 2021-04-08 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods and compositions for identifying neoantigens for use in treating and preventing cancer |
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GB9103974D0 (en) | 1991-02-26 | 1991-04-10 | Norsk Hydro As | Therapeutically useful peptides or peptide fragments |
EP0765386B1 (de) | 1994-06-14 | 2014-12-10 | The Board Of Trustees Of The Leland Stanford Junior University | Methode zur in vivo aktivierung von t-zellen mit antigen inkubierten dendritischen zellen |
US5968506A (en) | 1995-08-04 | 1999-10-19 | Geron Corporation | Purified telomerase |
PT880360E (pt) * | 1996-02-12 | 2003-02-28 | Ml Lab Plc | Novos metodos de vacinacao e consequentes vacinas que compreendem um acido nucleico que codifica um primeiro epitopo e um peptido que contem um segundo epitopo |
US5951976A (en) | 1996-03-28 | 1999-09-14 | Whitenead Institute For Biomedical Research | Opsonin-enhanced cells, and methods of modulating an immune response to an antigen |
WO1998001493A1 (en) * | 1996-07-08 | 1998-01-15 | Jvs-Polymers Oy | High impact strength biodegradable material |
US5770422A (en) | 1996-07-08 | 1998-06-23 | The Regents Of The University Of California | Human telomerase |
KR20000048820A (ko) | 1996-10-01 | 2000-07-25 | 게론 코포레이션 | 텔로머라제 역전사 효소 |
US7390891B1 (en) | 1996-11-15 | 2008-06-24 | Amgen Inc. | Polynucleotides encoding a telomerase component TP2 |
US6337200B1 (en) | 1998-03-31 | 2002-01-08 | Geron Corporation | Human telomerase catalytic subunit variants |
AU3456099A (en) | 1998-03-31 | 1999-10-18 | Geron Corporation | Methods and compositions for eliciting an immune response to a telomerase antigen |
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1990
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1998
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1999
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2002
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2006
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2010
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