DE69910580D1 - Von der telomerase abgeleitete antigene peptide - Google Patents
Von der telomerase abgeleitete antigene peptideInfo
- Publication number
- DE69910580D1 DE69910580D1 DE69910580T DE69910580T DE69910580D1 DE 69910580 D1 DE69910580 D1 DE 69910580D1 DE 69910580 T DE69910580 T DE 69910580T DE 69910580 T DE69910580 T DE 69910580T DE 69910580 D1 DE69910580 D1 DE 69910580D1
- Authority
- DE
- Germany
- Prior art keywords
- telomerase
- peptides derived
- antigenic peptides
- antigenic
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108010017842 Telomerase Proteins 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001154—Enzymes
- A61K39/001157—Telomerase or TERT [telomerase reverse transcriptase]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO983141 | 1998-07-08 | ||
NO19983141A NO313834B1 (no) | 1998-07-08 | 1998-07-08 | Telomeraseprotein eller -peptider, nukleinsyresekvenser som koder for disse, farmasöytiske sammensetninger inneholdende disseog fremgangsmÕter for Õ fremstille slike farmasöytiskesammensetninger til profylakse mot og behandling av kreft, samt |
PCT/NO1999/000220 WO2000002581A1 (en) | 1998-07-08 | 1999-06-30 | Antigenic peptides derived from telomerase |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69910580D1 true DE69910580D1 (de) | 2003-09-25 |
DE69910580T2 DE69910580T2 (de) | 2004-06-24 |
DE69910580T3 DE69910580T3 (de) | 2009-11-26 |
Family
ID=19902234
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69942072T Expired - Lifetime DE69942072D1 (de) | 1998-07-08 | 1999-06-30 | Von der Telomerase abgeleitete antigene Peptide |
DE1999610580 Expired - Lifetime DE69910580T3 (de) | 1998-07-08 | 1999-06-30 | Von der telomerase abgeleitete antigene peptide |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69942072T Expired - Lifetime DE69942072D1 (de) | 1998-07-08 | 1999-06-30 | Von der Telomerase abgeleitete antigene Peptide |
Country Status (20)
Country | Link |
---|---|
US (2) | US7030211B1 (de) |
EP (4) | EP1362597B2 (de) |
JP (2) | JP4618657B2 (de) |
CN (1) | CN100376290C (de) |
AR (2) | AR020601A1 (de) |
AT (2) | ATE458494T1 (de) |
AU (1) | AU756094B2 (de) |
CA (2) | CA2336743C (de) |
CY (1) | CY1109978T1 (de) |
CZ (1) | CZ303215B6 (de) |
DE (2) | DE69942072D1 (de) |
DK (2) | DK1362597T3 (de) |
ES (2) | ES2200526T5 (de) |
HK (1) | HK1039068B (de) |
HU (1) | HU230007B1 (de) |
NO (1) | NO313834B1 (de) |
PL (1) | PL203815B1 (de) |
PT (2) | PT1093381E (de) |
TW (1) | TWI261617B (de) |
WO (1) | WO2000002581A1 (de) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6475789B1 (en) | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
GB2321642B8 (en) | 1996-10-01 | 2006-08-22 | Geron Corp | Human telomerase reverse transcriptase promoter |
US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
US7413864B2 (en) | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
US7622549B2 (en) | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
AU3456099A (en) | 1998-03-31 | 1999-10-18 | Geron Corporation | Methods and compositions for eliciting an immune response to a telomerase antigen |
US7402307B2 (en) | 1998-03-31 | 2008-07-22 | Geron Corporation | Method for identifying and killing cancer cells |
DE69934426T2 (de) | 1998-10-29 | 2007-10-04 | Whitehead Institute For Biomedical Research, Cambridge | KREBSIMMUNTHERAPIE UND KREBSDIAGNOSE UNTER VERWENDUNG UNIVERSELLER TUMORASSOZIIERTER ANTIGENE EINSCHLIESSLICH hTERT |
JP2002541811A (ja) * | 1999-04-09 | 2002-12-10 | バイオミラ,インコーポレイテッド | テロメラーゼ特異的癌ワクチン |
EP1257284A4 (de) * | 2000-02-15 | 2005-12-21 | Univ California | Ein universelles vakzin und ein verfahren zur behandlung von krebs mit telomerase reverse transkriptase |
AU2001241533A1 (en) | 2000-02-15 | 2001-08-27 | The Regents Of The University Of California | A universal vaccine and method for treating cancer employing telomerase reverse transcriptase |
FR2812087B1 (fr) * | 2000-07-21 | 2007-05-11 | Inst Nat Sante Rech Med | Procede de criblage de peptides utilisables en immunotherapie |
GB0031430D0 (en) * | 2000-12-22 | 2001-02-07 | Norsk Hydro As | Polypeptides |
GB0105238D0 (en) * | 2001-03-02 | 2001-04-18 | Norsk Hydro As | Vaccines |
GB0112342D0 (en) * | 2001-05-21 | 2001-07-11 | Norsk Hydro As | Polypeptides |
ES2527946T3 (es) * | 2003-03-05 | 2015-02-02 | Dendreon Corporation | Composiciones y métodos que emplean polipéptidos de marco de lectura alternativa para el tratamiento de cáncer y enfermedades infecciosas |
EP1748067A1 (de) * | 2005-07-29 | 2007-01-31 | Institut Pasteur | Polynukleotide, die für MHC Klasse I-beschränkte Epitope der hTERT, Analoge und Polyepitope kodieren |
US10767167B2 (en) | 2005-07-29 | 2020-09-08 | Institut Pasteur | Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes |
CA2652310A1 (en) * | 2006-01-19 | 2007-08-23 | The Regents Of The University Of California | Human telomerase reverse transcriptase peptides |
US9732131B2 (en) | 2006-02-27 | 2017-08-15 | Calviri, Inc. | Identification and use of novopeptides for the treatment of cancer |
WO2008010010A1 (en) * | 2006-07-12 | 2008-01-24 | Vaxon Biotech | Identification, optimization and use of cryptic hla-b7 epitopes for immunotherapy |
EP1887084A1 (de) * | 2006-08-10 | 2008-02-13 | International Investment and Patents SA | Plasmide mit immunologischer Wirkung |
JP5207354B2 (ja) * | 2008-03-12 | 2013-06-12 | 独立行政法人産業技術総合研究所 | 転写抑制ペプチド及びその遺伝子 |
EP2310044B1 (de) * | 2008-06-16 | 2016-08-24 | Mediolanum Farmaceutici S.p.A. | Antitumorale immuntherapie |
US20110318380A1 (en) * | 2008-10-01 | 2011-12-29 | Dako Denmark A/S | MHC Multimers in Cancer Vaccines and Immune Monitoring |
GB0821616D0 (en) | 2008-11-26 | 2008-12-31 | Lytix Biopharma As | Compounds |
ES2730927T3 (es) | 2009-11-10 | 2019-11-13 | Allegro Pharmaceuticals Llc | Composiciones y métodos para inhibir la adhesión celular o dirigir agentes diagnósticos o terapéuticos a sitios de unión a RGD |
US11673914B2 (en) | 2009-11-10 | 2023-06-13 | Allegro Pharmaceuticals, LLC | Peptide therapies for reduction of macular thickening |
EP3581649A1 (de) * | 2010-02-16 | 2019-12-18 | Ultimovacs ASA | Polypeptide |
FR2960542B1 (fr) * | 2010-05-27 | 2012-08-17 | Esther Suzy Arlette Fellous | Peptide en tant que medicament, en particulier pour le traitement du cancer |
JP6106159B2 (ja) | 2011-05-09 | 2017-03-29 | アレグロ ファーマシューティカルズ インコーポレイテッドAllegro Pharmaceuticals,Inc. | R−g−システイン酸ペプチドを含む医薬組成物 |
WO2013167298A1 (en) * | 2012-05-11 | 2013-11-14 | Kael-Gemvax Co., Ltd. | Anti-inflammatory peptides and composition comprising the same |
EP3333180B1 (de) * | 2012-05-11 | 2019-08-21 | KAEL-GemVax Co.,Ltd | Antientzündliche peptide und zusammensetzungen die diese enthaltend |
US9907837B2 (en) | 2012-05-11 | 2018-03-06 | Gemvax & Kael Co., Ltd. | Composition for preventing or treating cachexia |
JP6272853B2 (ja) * | 2012-07-11 | 2018-01-31 | ジェムバックス アンド カエル カンパニー,リミティド | 細胞透過性ペプチド、それを含んだコンジュゲート、及びそれを含んだ組成物 |
US20150125438A1 (en) * | 2012-07-20 | 2015-05-07 | Sang Jae Kim | Anti-Inflammatory Peptides and Composition Comprising the Same |
TWI616530B (zh) * | 2012-09-19 | 2018-03-01 | 傑姆維克斯&凱爾有限公司 | 穿膜胜肽以及包含該胜肽之共軛物及組成物(一) |
CN104768967B (zh) * | 2012-09-19 | 2019-02-15 | 珍白斯凯尔有限公司 | 细胞穿透性肽、包含该肽的缀合物、及包含该缀合物的组合物 |
KR102038487B1 (ko) | 2012-09-19 | 2019-10-30 | 주식회사 젬백스앤카엘 | 텔로머라제 펩티드를 포함하는 항균 또는 항진균용 조성물 |
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KR102166542B1 (ko) | 2012-09-28 | 2020-10-16 | 주식회사 젬백스앤카엘 | 줄기세포 검출을 위한 텔로머라제 유래 펩티드 및 조영물질의 컨쥬게이트 및 이를 포함하는 조영제 |
CN102875657B (zh) * | 2012-10-22 | 2014-04-09 | 南京工业大学 | 一种制备端粒酶多肽疫苗的方法 |
KR102106756B1 (ko) | 2012-12-13 | 2020-05-06 | 주식회사 젬백스앤카엘 | 자외선에 의한 피부 손상 예방 또는 치료용 조성물 |
KR102093093B1 (ko) | 2012-12-13 | 2020-03-25 | 주식회사 젬백스앤카엘 | 피부 노화 개선용 조성물 |
US9907838B2 (en) * | 2013-04-19 | 2018-03-06 | Gemvax & Kael Co., Ltd. | Composition and methods for treating ischemic damage |
WO2014178680A1 (ko) * | 2013-05-03 | 2014-11-06 | 주식회사 카엘젬백스 | Hsp 발현 억제 펩티드 및 이를 포함하는 조성물 |
ES2927473T3 (es) | 2013-06-07 | 2022-11-07 | Gemvax & Kael Co Ltd | GV1001, gemcitabina y capecitabina para su uso en el tratamiento del cáncer de páncreas en pacientes con un nivel inicial de eotaxina elevado |
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EP3020724A4 (de) * | 2013-07-12 | 2017-01-18 | Gemvax & Kael Co., Ltd. | Zellenpenetrierendes peptid und konjugat damit |
WO2015023132A1 (ko) * | 2013-08-14 | 2015-02-19 | 주식회사 카엘젬백스 | 다발성 경화증 치료 및 예방용 조성물 |
GB201315946D0 (en) * | 2013-09-06 | 2013-10-23 | Immune Targeting Systems Its Ltd | Oncology vaccine |
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KR102314231B1 (ko) * | 2013-12-17 | 2021-10-19 | 주식회사 젬백스앤카엘 | 전립선 암 치료용 조성물 |
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KR101503341B1 (ko) | 2014-03-12 | 2015-03-18 | 국립암센터 | 자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법 |
ES2908096T3 (es) | 2014-04-11 | 2022-04-27 | Gemvax & Kael Co Ltd | Péptido con actividad inhibidora de la fibrosis y composición que lo contiene |
KR102232320B1 (ko) | 2014-04-30 | 2021-03-26 | 주식회사 젬백스앤카엘 | 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법 |
WO2015170790A1 (ko) * | 2014-05-09 | 2015-11-12 | 주식회사 카엘젬백스 | 허혈성 손상 치료 및 예방용 조성물 |
CN105597078B (zh) * | 2014-05-29 | 2019-01-25 | 深圳市盛景基因医疗有限公司 | 一种治疗癌症的肽变体及其应用 |
KR102166543B1 (ko) | 2014-06-02 | 2020-10-16 | 주식회사 젬백스앤카엘 | 켈로이드 억제용 조성물 및 그 억제 방법 |
KR102397510B1 (ko) * | 2014-12-23 | 2022-05-13 | 주식회사 젬백스앤카엘 | 난소 기능 보존용 펩티드 및 이를 포함하는 조성물 |
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US10835582B2 (en) | 2015-02-27 | 2020-11-17 | Gemvax & Kael Co. Ltd. | Peptide for preventing hearing loss, and composition comprising same |
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JP7114481B2 (ja) | 2016-04-07 | 2022-08-08 | ジェムバックス アンド カエル カンパニー,リミティド | テロメラーゼ活性の増加及びテロメアの延長の効能を有するペプチド、及びこれを含む組成物 |
EP3523332B1 (de) | 2017-01-06 | 2021-12-29 | Eutilex Co., Ltd. | Anti-human-4-1-bb-antikörper und deren verwendung |
EP3576764A4 (de) | 2017-02-03 | 2020-12-16 | The Medical College of Wisconsin, Inc. | Kras-peptid-impfstoffzusammensetzungen und verfahren zur verwendung |
WO2018223092A1 (en) | 2017-06-02 | 2018-12-06 | Arizona Board Of Regents On Behalf Of Arizona State University | A method to create personalized cancer vaccines |
US12025615B2 (en) | 2017-09-15 | 2024-07-02 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods of classifying response to immunotherapy for cancer |
WO2020002650A1 (en) | 2018-06-29 | 2020-01-02 | Targovax Asa | A formulation |
WO2021067550A1 (en) | 2019-10-02 | 2021-04-08 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods and compositions for identifying neoantigens for use in treating and preventing cancer |
JP2023521895A (ja) * | 2020-04-17 | 2023-05-25 | リネージ セル セラピューティクス インコーポレイテッド | テロメラーゼ逆転写酵素に特異的なmhc拘束性免疫原性ペプチド、その複合体コンジュゲート、およびそれらを使用する方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9103974D0 (en) | 1991-02-26 | 1991-04-10 | Norsk Hydro As | Therapeutically useful peptides or peptide fragments |
WO1995034638A1 (en) | 1994-06-14 | 1995-12-21 | The Board Of Trustees Of Leland Stanford Junior University | Methods for in vivo t cell activation by antigen-pulsed dendritic cells |
US5968506A (en) | 1995-08-04 | 1999-10-19 | Geron Corporation | Purified telomerase |
ES2184990T3 (es) * | 1996-02-12 | 2003-04-16 | Ml Lab Plc | Nuevos metodos de vacunacion y vacunas para los mismos que comprenden un acido nucleico que codifica un primer epitope y un peptido que contiene un segundo epitope. |
BR9708387A (pt) | 1996-03-28 | 2000-01-04 | Genitrix Llc | Processo para vacinação de um mamìfero a um antìgeno selecionado, células patogênica e hospedeira, composição de vacina, ácido nucleico, e, opsonina engenheirada. |
US5770422A (en) | 1996-07-08 | 1998-06-23 | The Regents Of The University Of California | Human telomerase |
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AU3456099A (en) | 1998-03-31 | 1999-10-18 | Geron Corporation | Methods and compositions for eliciting an immune response to a telomerase antigen |
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