DE69907137T2 - Autoklavierbare pharmazeutische zusammensetzungen mit komplexbildner - Google Patents

Autoklavierbare pharmazeutische zusammensetzungen mit komplexbildner

Info

Publication number
DE69907137T2
DE69907137T2 DE69907137T DE69907137T DE69907137T2 DE 69907137 T2 DE69907137 T2 DE 69907137T2 DE 69907137 T DE69907137 T DE 69907137T DE 69907137 T DE69907137 T DE 69907137T DE 69907137 T2 DE69907137 T2 DE 69907137T2
Authority
DE
Germany
Prior art keywords
autoclavable
illuminators
complex
pharmaceutical compositions
ketotifen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69907137T
Other languages
English (en)
Other versions
DE69907137D1 (de
Inventor
Lajos Kis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharma GmbH
Novartis AG
Original Assignee
Novartis Pharma GmbH
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8235893&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69907137(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Pharma GmbH, Novartis AG filed Critical Novartis Pharma GmbH
Application granted granted Critical
Publication of DE69907137D1 publication Critical patent/DE69907137D1/de
Publication of DE69907137T2 publication Critical patent/DE69907137T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69907137T 1998-01-15 1999-01-13 Autoklavierbare pharmazeutische zusammensetzungen mit komplexbildner Expired - Lifetime DE69907137T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98810016A EP0938896A1 (de) 1998-01-15 1998-01-15 In Autoklaven behandelbare pharmazeutische Zusammensetzungen mit Komplexbildner
PCT/EP1999/000160 WO1999036055A1 (en) 1998-01-15 1999-01-13 Autoclavable pharmaceutical compositions containing a chelating agent

Publications (2)

Publication Number Publication Date
DE69907137D1 DE69907137D1 (de) 2003-05-28
DE69907137T2 true DE69907137T2 (de) 2003-11-27

Family

ID=8235893

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69943051T Expired - Lifetime DE69943051D1 (de) 1998-01-15 1999-01-13 Augentropfen enthaltend Ketotifen
DE69907137T Expired - Lifetime DE69907137T2 (de) 1998-01-15 1999-01-13 Autoklavierbare pharmazeutische zusammensetzungen mit komplexbildner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69943051T Expired - Lifetime DE69943051D1 (de) 1998-01-15 1999-01-13 Augentropfen enthaltend Ketotifen

Country Status (12)

Country Link
US (2) US6468548B1 (de)
EP (4) EP0938896A1 (de)
JP (2) JP5442919B2 (de)
AT (2) ATE491434T1 (de)
AU (1) AU742920B2 (de)
CA (1) CA2315767C (de)
CY (1) CY1111126T1 (de)
DE (2) DE69943051D1 (de)
DK (2) DK1172098T3 (de)
ES (2) ES2198127T3 (de)
PT (2) PT1172098E (de)
WO (1) WO1999036055A1 (de)

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US6777429B1 (en) 1999-07-23 2004-08-17 Novartis Ag Ophthalmic composition
JP2001158750A (ja) * 1999-12-02 2001-06-12 Lion Corp 眼科用組成物及び抗アレルギー薬の持続性向上方法
WO2001052812A1 (de) * 2000-01-20 2001-07-26 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Diclofenamid suspensionsgel
DE60117043T2 (de) * 2000-11-22 2006-07-13 Rxkinetix, Inc., Louisville Behandlung von mukositis
US20040214797A1 (en) * 2001-05-07 2004-10-28 Allergan, Inc. Preserved pharmaceutical compositions comprising cyclodextrins
AR034372A1 (es) * 2001-06-08 2004-02-18 Novartis Ag Composiciones farmaceuticas
WO2002100436A2 (en) * 2001-06-08 2002-12-19 Novartis Ag Ophthalmic once-a-day composition
ATE547122T1 (de) * 2001-11-21 2012-03-15 Novartis Pharma Gmbh Zusammensetzung zur stabilisierung von hyaluronsäure
DE10222561B4 (de) * 2002-05-17 2009-12-10 Dr. Franz Köhler Chemie GmbH Protektive Lösung zur Verhinderung von Ischämieschäden
ES2685436T3 (es) * 2002-12-09 2018-10-09 Abraxis Bioscience, Llc Composiciones y procedimientos para administración de agentes farmacológicos
EP1454636A1 (de) * 2003-03-04 2004-09-08 Dompé S.P.A. Sterilisierung von Glucocorticoid-Arzneimittelteilchen zur Anwendung in der Lunge
US6933289B2 (en) * 2003-07-01 2005-08-23 Allergan, Inc. Inhibition of irritating side effects associated with use of a topical ophthalmic medication
US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20050234018A1 (en) * 2004-04-15 2005-10-20 Allergan, Inc. Drug delivery to the back of the eye
GB0410995D0 (en) 2004-05-17 2004-06-23 Norton Healthcare Ltd Heat sterilization of glucocorticosteroids
CA2585266C (en) * 2004-10-25 2010-10-19 Bausch & Lomb Incorporated Ophthalmic compositions and methods of using the same
US20070208058A1 (en) * 2004-10-25 2007-09-06 Bryant Roy W Stable Pharmaceutical Compositions and Methods of Making and Using Same
US20060089384A1 (en) * 2004-10-25 2006-04-27 Minno George E Ophthalmic compositions and methods of using the same
US20060094700A1 (en) * 2004-11-02 2006-05-04 Allergan, Inc. Heat sterilization of a steroid in the presence of phosphate
GB0425266D0 (en) 2004-11-16 2004-12-15 Norton Healthcare Ltd Pharmaceutical manufacturing process
US7178703B2 (en) 2004-11-23 2007-02-20 Allergan, Inc. Autoclaveable small-volume dropper bottle
US20060186005A1 (en) * 2005-02-24 2006-08-24 Sina Ebnesajjad Terminally sterilizing pharmaceutical package
US20060243696A1 (en) * 2005-04-27 2006-11-02 Spada Lon T Tip design for reducing capillary leakage and water loss for plastic container closures
US20070048388A1 (en) * 2005-08-26 2007-03-01 Fu-Pao Tsao Stabilized and preserved ketotifen ophthalmic compositions
US20070048389A1 (en) * 2005-08-26 2007-03-01 Fu-Pao Tsao Stabilized and preserved ketotifen ophthalmic compositions
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
PT1965787E (pt) * 2005-11-30 2013-07-05 Endo Pharmaceuticals Inc Tratamento de xerostomia com um antioxidante que contém enxofre
CA2646424C (en) 2006-03-17 2015-12-29 Johnson & Johnson Vision Care, Inc. Methods for stabilizing oxidatively unstable compositions
US20070238789A1 (en) * 2006-03-31 2007-10-11 Chin-Ming Chang Prednisolone acetate compositions
SG177934A1 (en) * 2006-09-29 2012-02-28 Johnson & Johnson Vision Care Methods and ophthalmic devices used in the treatment of ocular allergies
WO2008153761A1 (en) * 2007-05-23 2008-12-18 Mastcell Pharmaceuticals, Inc. Methods
US20090005362A1 (en) * 2007-06-26 2009-01-01 Vo Toan P Compositions Comprising Antihistamines or Mast Cell Stabilizers, and Methods of Making and Using Same
JP5460996B2 (ja) * 2007-10-19 2014-04-02 大正製薬株式会社 眼科用剤
MD3975C2 (ro) * 2007-11-07 2010-06-30 Технический университет Молдовы Sistem de orientare a instalaţiei solare paraboloidale (variante)
WO2009142772A2 (en) 2008-05-23 2009-11-26 Mastcell Pharmaceuticals, Inc. Methods and treatment for allergies and inflammation associated with gastrointestinal diseases
US8741930B2 (en) * 2008-10-24 2014-06-03 Bridge Pharma, Inc. Treating xerophthalmia with norketotifen
WO2010059894A1 (en) * 2008-11-21 2010-05-27 Bridge Pharma, Inc. Ocular formulations of norketotifen
JP6462201B2 (ja) * 2012-06-14 2019-01-30 ロート製薬株式会社 水性眼科組成物
ITMI20122002A1 (it) * 2012-11-26 2014-05-27 Farmacologico Milanese Srl Lab Preparazioni farmaceutiche liquide stabilizzate
US10174006B2 (en) * 2013-06-06 2019-01-08 Novartis Ag Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease
WO2015105135A1 (ja) * 2014-01-10 2015-07-16 参天製薬株式会社 ピリジルアミノ酢酸化合物含有医薬組成物
WO2015169728A1 (en) * 2014-05-07 2015-11-12 Croma-Pharma Gesellschaft M.B.H. Aqueous ophthalmic solution and method for treating dry eye syndrome
GB201419540D0 (en) * 2014-11-03 2014-12-17 Nanomerics Ltd Delivery of drugs
US9694003B2 (en) 2015-10-15 2017-07-04 Bridge Pharma, Inc. Formulations and methods for treating high intraocular pressure
CN106109407A (zh) * 2016-08-25 2016-11-16 安徽环球药业股份有限公司 盐酸安妥沙星氯化钠注射液的配制方法
HRP20220046T1 (hr) 2016-11-29 2022-04-15 Oculis SA Priprema čvrstih kompleksa ciklodekstrina za uporabu oftalmološki aktivnih farmaceutskih sastojka
CN109833294B (zh) * 2019-04-19 2020-06-09 江苏远恒药业有限公司 一种盐酸洛美沙星滴眼液及其制备工艺
WO2021236671A1 (en) * 2020-05-18 2021-11-25 Vyluma Inc. Low-dose carbachol compositions and methods for treatment of night vision disturbance

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GB1399834A (en) * 1971-05-12 1975-07-02 Fisons Ltd Pharmaceutical compositions
JPS5428810A (en) * 1977-08-01 1979-03-03 American Home Prod Pharmaceutical composition for eye disease containing 1*33dioxoo1hhbenzo *d * e* isoquinolinee2*3h**acetic acid
JPS62277323A (ja) * 1986-02-19 1987-12-02 Sankyo Co Ltd フマル酸ケトチフエン含有点眼液の製法
US5032392A (en) * 1986-09-04 1991-07-16 Vision Pharmaceuticals Aqueous ophthalmic solutions for the treatment of dryness and/or irritation of human or animal eyes
US5165918A (en) * 1988-06-28 1992-11-24 Ciba-Geigy Corporation Antimicrobial ophthalmic solutions containing dodecyl-dimethyl-(2 phenoxyethyl)-ammonium bromide and methods of using the same
CA2044878C (en) * 1990-08-07 2000-12-26 Tacey X. Viegas Thermally reversible and irreversible gels
EP0492902A1 (de) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituierte Pyridine zur Anwendung in der Behandlung von Glaukoma
EP0492904A1 (de) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituierte Benzol-Derivate zur Anwendung in der Behandlung von Glaukom
US5182102A (en) * 1991-07-12 1993-01-26 Alcon Laboratories, Inc. Anti-glaucoma compositions
AU666957B2 (en) * 1992-08-28 1996-02-29 Alcon Laboratories, Inc. Use of certain anionic surfactants to enhance antimicrobial effectiveness of ophthalmic compositions
ES2079994B1 (es) * 1992-10-07 1996-08-01 Cusi Lab Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica.
US5624893A (en) * 1993-10-14 1997-04-29 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
JP3597239B2 (ja) * 1994-03-31 2004-12-02 ライオン株式会社 安定な点眼剤
JPH07324034A (ja) * 1994-05-30 1995-12-12 Toa Yakuhin Kk フマル酸ケトチフェン含有の点眼剤
JP3055753B2 (ja) * 1994-07-05 2000-06-26 昭和薬品化工株式会社 フマル酸ケトチフェン含有点眼液
US5576311A (en) * 1994-11-30 1996-11-19 Pharmos Corporation Cyclodextrins as suspending agents for pharmaceutical suspensions
US5683993A (en) * 1995-06-22 1997-11-04 Ciba Vision Corporation Compositions and methods for stabilizing polymers
FR2738149B1 (fr) * 1995-09-06 1997-11-14 Chauvin Lab Sa Collyre a base d'indometacine pret a l'emploi
JPH09301873A (ja) * 1996-05-13 1997-11-25 Senju Pharmaceut Co Ltd サルファ剤の可溶化方法及びサルファ剤を可溶化させた水性薬剤
DE69705057T2 (de) * 1996-09-20 2001-09-20 Bausch & Lomb Verfahren und zusammensetzung zur wiederbenetzung von kontaktlinsen und linderung der augentrockenheit
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US6395756B2 (en) * 1999-12-23 2002-05-28 Novartis Ag Use of ophthalmic agent

Also Published As

Publication number Publication date
ES2198127T3 (es) 2004-01-16
DK1047406T3 (da) 2003-07-21
AU2616999A (en) 1999-08-02
EP1172098B1 (de) 2010-12-15
CY1111126T1 (el) 2015-06-11
ES2356229T3 (es) 2011-04-06
WO1999036055A1 (en) 1999-07-22
CA2315767C (en) 2008-10-28
JP5587237B2 (ja) 2014-09-10
DK1172098T3 (da) 2011-03-14
JP2002509101A (ja) 2002-03-26
JP5442919B2 (ja) 2014-03-19
ATE491434T1 (de) 2011-01-15
US6468548B1 (en) 2002-10-22
AU742920B2 (en) 2002-01-17
DE69943051D1 (de) 2011-01-27
EP0938896A1 (de) 1999-09-01
US6776982B2 (en) 2004-08-17
EP1172098A1 (de) 2002-01-16
EP2281554A1 (de) 2011-02-09
ATE238036T1 (de) 2003-05-15
EP1047406B1 (de) 2003-04-23
EP1047406A1 (de) 2000-11-02
DE69907137D1 (de) 2003-05-28
JP2011168601A (ja) 2011-09-01
PT1172098E (pt) 2011-02-01
PT1047406E (pt) 2003-08-29
CA2315767A1 (en) 1999-07-22
US20020165254A1 (en) 2002-11-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN