DE69837257T2 - Analytische versuchsanordnung für auf membranen basierende versuche - Google Patents
Analytische versuchsanordnung für auf membranen basierende versuche Download PDFInfo
- Publication number
- DE69837257T2 DE69837257T2 DE69837257T DE69837257T DE69837257T2 DE 69837257 T2 DE69837257 T2 DE 69837257T2 DE 69837257 T DE69837257 T DE 69837257T DE 69837257 T DE69837257 T DE 69837257T DE 69837257 T2 DE69837257 T2 DE 69837257T2
- Authority
- DE
- Germany
- Prior art keywords
- reaction membrane
- support layer
- analytical device
- membrane
- absorbent body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000012528 membrane Substances 0.000 title claims abstract description 182
- 238000004458 analytical method Methods 0.000 title 1
- 239000002250 absorbent Substances 0.000 claims abstract description 67
- 230000002745 absorbent Effects 0.000 claims abstract description 67
- 239000000853 adhesive Substances 0.000 claims abstract description 27
- 239000013076 target substance Substances 0.000 claims abstract description 27
- 230000001070 adhesive effect Effects 0.000 claims abstract description 25
- 239000007788 liquid Substances 0.000 claims abstract description 18
- 239000000126 substance Substances 0.000 claims abstract description 9
- 238000004891 communication Methods 0.000 claims abstract description 4
- 239000000463 material Substances 0.000 claims description 54
- 238000003556 assay Methods 0.000 claims description 29
- 230000006835 compression Effects 0.000 claims description 15
- 238000007906 compression Methods 0.000 claims description 15
- 239000000020 Nitrocellulose Substances 0.000 claims description 13
- 229920001220 nitrocellulos Polymers 0.000 claims description 13
- 239000000427 antigen Substances 0.000 claims description 10
- 102000036639 antigens Human genes 0.000 claims description 10
- 108091007433 antigens Proteins 0.000 claims description 10
- 230000027455 binding Effects 0.000 claims description 7
- 229920000728 polyester Polymers 0.000 claims description 7
- 239000012530 fluid Substances 0.000 claims description 5
- 229920002457 flexible plastic Polymers 0.000 claims description 4
- 239000003365 glass fiber Substances 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 abstract description 23
- 238000001514 detection method Methods 0.000 abstract description 5
- 239000000523 sample Substances 0.000 description 60
- 102000005962 receptors Human genes 0.000 description 42
- 108020003175 receptors Proteins 0.000 description 42
- 230000035945 sensitivity Effects 0.000 description 16
- 230000000903 blocking effect Effects 0.000 description 12
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 11
- FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 description 11
- 239000000243 solution Substances 0.000 description 11
- 239000003153 chemical reaction reagent Substances 0.000 description 10
- 239000004033 plastic Substances 0.000 description 10
- 229920003023 plastic Polymers 0.000 description 10
- 238000012360 testing method Methods 0.000 description 9
- 230000001965 increasing effect Effects 0.000 description 8
- 239000003292 glue Substances 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 7
- 102000004169 proteins and genes Human genes 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 6
- 229940098773 bovine serum albumin Drugs 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- 238000012801 analytical assay Methods 0.000 description 5
- 238000002965 ELISA Methods 0.000 description 4
- 239000004677 Nylon Substances 0.000 description 4
- 229920001778 nylon Polymers 0.000 description 4
- 239000011148 porous material Substances 0.000 description 4
- 229920001213 Polysorbate 20 Polymers 0.000 description 3
- 239000003599 detergent Substances 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 239000002953 phosphate buffered saline Substances 0.000 description 3
- -1 polycarbon Polymers 0.000 description 3
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical class OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 2
- 241000725303 Human immunodeficiency virus Species 0.000 description 2
- 229920001214 Polysorbate 60 Polymers 0.000 description 2
- 125000003277 amino group Chemical group 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 229920002301 cellulose acetate Polymers 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000000873 masking effect Effects 0.000 description 2
- 229920000056 polyoxyethylene ether Polymers 0.000 description 2
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 2
- 229920002554 vinyl polymer Polymers 0.000 description 2
- 241000701022 Cytomegalovirus Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000590002 Helicobacter pylori Species 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 201000005485 Toxoplasmosis Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000011152 fibreglass Substances 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 102000006240 membrane receptors Human genes 0.000 description 1
- 108020004084 membrane receptors Proteins 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 230000009871 nonspecific binding Effects 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000007925 protein solubilization Effects 0.000 description 1
- 238000001799 protein solubilization Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54391—Immunochromatographic test strips based on vertical flow
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US823936 | 1997-03-25 | ||
| US08/823,936 US5885526A (en) | 1997-03-25 | 1997-03-25 | Analytical device for membrane-based assays |
| PCT/US1998/005373 WO1998043083A1 (en) | 1997-03-25 | 1998-03-18 | Analytical device for membrane-based assays |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69837257D1 DE69837257D1 (de) | 2007-04-19 |
| DE69837257T2 true DE69837257T2 (de) | 2007-11-08 |
Family
ID=25240175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69837257T Expired - Lifetime DE69837257T2 (de) | 1997-03-25 | 1998-03-18 | Analytische versuchsanordnung für auf membranen basierende versuche |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5885526A (https=) |
| EP (1) | EP0988546B1 (https=) |
| JP (1) | JP4040110B2 (https=) |
| CN (1) | CN1125983C (https=) |
| AT (1) | ATE356354T1 (https=) |
| CA (1) | CA2285048C (https=) |
| DE (1) | DE69837257T2 (https=) |
| ES (1) | ES2283050T3 (https=) |
| WO (1) | WO1998043083A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451607B1 (en) | 1998-05-07 | 2002-09-17 | Litmus Concepts, Inc. | External dried-reagent control for analytical test devices |
| US6171870B1 (en) * | 1998-08-06 | 2001-01-09 | Spectral Diagnostics, Inc. | Analytical test device and method for use in medical diagnoses |
| US6410341B1 (en) * | 1998-08-06 | 2002-06-25 | Spectral Diagnostics, Inc. | Analytical test device and method for use in medical diagnoses |
| US6214629B1 (en) * | 1998-08-06 | 2001-04-10 | Spectral Diagnostics, Inc. | Analytical test device and method for use in medical diagnoses |
| US7011940B1 (en) * | 1999-04-14 | 2006-03-14 | Medical Discovery Partners Llc | Quality control for cytochemical assays |
| US6281004B1 (en) * | 1999-04-14 | 2001-08-28 | Cytologix Corporation | Quality control for cytochemical assays |
| FR2792724B1 (fr) * | 1999-04-26 | 2001-05-25 | Biomerieux Sa | Dispositif de prelevement et de conservation d'un echantillon biologique et son procede de mise en oeuvre |
| JP2001083162A (ja) * | 1999-09-17 | 2001-03-30 | Fuji Photo Film Co Ltd | 膜状生体高分子吸着材及び吸着用キット |
| US6632681B1 (en) | 2000-07-24 | 2003-10-14 | Ey Laboratories | Reagent delivery device and method of use |
| US20030104492A1 (en) * | 2000-12-15 | 2003-06-05 | Albert Chu | Flow-through membrane assays for carbohydrates using labeled lectins |
| US20040241876A1 (en) * | 2000-12-22 | 2004-12-02 | France Fannes | Flow through assay device, diagnostic kit comprising said assay device and use of said assay device in the detection of an analyte present in a sample |
| US7087389B2 (en) | 2001-02-09 | 2006-08-08 | Council Of Scientific & Industrial Research | Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity |
| US7531362B2 (en) | 2001-06-07 | 2009-05-12 | Medmira Inc. | Rapid diagnostic assay |
| US7205159B2 (en) * | 2001-08-20 | 2007-04-17 | Proteome Systems Intellectual Property Pty Ltd. | Diagnostic testing process and apparatus |
| WO2003016902A1 (en) * | 2001-08-20 | 2003-02-27 | Proteome Systems Intellectual Property Pty Ltd | Diagnostic testing process and apparatus |
| ATE358274T1 (de) * | 2001-12-12 | 2007-04-15 | Proteome Systems Intellectual | Diagnostisches testverfahren |
| WO2003098215A1 (en) * | 2002-05-16 | 2003-11-27 | Medmira Inc. | Rapid vaccinia antibody detection device, method and test kit |
| US20060205086A1 (en) * | 2002-10-24 | 2006-09-14 | Spectral Diagnostics Inc. | Diagnostic device |
| US7256053B2 (en) * | 2002-10-24 | 2007-08-14 | Nanogen, Inc. | Diagnostic device for analyte detection |
| US7488450B2 (en) * | 2004-03-04 | 2009-02-10 | Beckman Coulter, Inc. | Analyte collection and detection devices |
| FR2872288B1 (fr) * | 2004-06-28 | 2007-08-03 | Biomerieux Sa | Dispositif d'analyse integre, adaptable sur un conteneur d'un echantillon a analyser |
| US20060019406A1 (en) * | 2004-07-23 | 2006-01-26 | Ning Wei | Lateral flow device for the detection of large pathogens |
| US20060068500A1 (en) * | 2004-09-28 | 2006-03-30 | Kimberly-Clark Worldwide, Inc. | Detecting yeast infections using a lateral flow assay |
| DK1843850T3 (en) | 2005-01-31 | 2015-12-07 | Realbio Technologies Ltd | LATERAL FLOW STEERING CAPILLAR DEVICE |
| US7189522B2 (en) | 2005-03-11 | 2007-03-13 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
| WO2006098804A2 (en) * | 2005-03-11 | 2006-09-21 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
| US20070141723A1 (en) * | 2005-12-16 | 2007-06-21 | Sompuram Seshi A | Immunohistochemistry staining controls |
| JP4860489B2 (ja) * | 2007-01-09 | 2012-01-25 | 浜松ホトニクス株式会社 | 免疫クロマト試験片の測定方法 |
| US7816090B2 (en) * | 2007-01-10 | 2010-10-19 | Ortho-Clinical Diagnostics, Inc. | Multiple immunochemistry assays on an element |
| EP2012126A1 (en) * | 2007-07-04 | 2009-01-07 | Koninklijke Philips Electronics N.V. | Porous biological assay substrate and method for producing such substrate |
| CN101603967B (zh) * | 2008-06-10 | 2015-02-18 | 英科新创(厦门)科技有限公司 | 快速检测人ABO/Rh/MN血型的方法及试剂盒 |
| WO2010007613A1 (en) | 2008-06-29 | 2010-01-21 | Realbio Technologies Ltd. | Liquid–transfer device particularly useful as a capturing device in a biological assay process |
| US20100022916A1 (en) | 2008-07-24 | 2010-01-28 | Javanbakhsh Esfandiari | Method and Apparatus for Collecting and Preparing Biological Samples for Testing |
| US8603835B2 (en) | 2011-02-10 | 2013-12-10 | Chembio Diagnostic Systems, Inc. | Reduced step dual path immunoassay device and method |
| US20130164193A1 (en) | 2011-12-22 | 2013-06-27 | Life Technologies Corporation | Sequential lateral flow capillary device for analyte determination |
| DK3578635T3 (da) | 2014-04-02 | 2022-02-07 | Chembio Diagnostic Systems Inc | Immunoassay, som anvender indfangningskonjugat |
| US9568404B2 (en) | 2014-05-16 | 2017-02-14 | Junyu Mai | Method and apparatus for biomolecule analysis |
| US20160116466A1 (en) | 2014-10-27 | 2016-04-28 | Chembio Diagnostic Systems, Inc. | Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses |
| EP3427049A4 (en) * | 2016-03-07 | 2019-10-16 | Nanodx Healthcare Pvt. Ltd. | ASSAY AND KITS FOR DETECTING ENDOTOXIN |
| EP4023338B1 (en) | 2016-04-14 | 2024-10-02 | Roche Diagnostics GmbH | Cartridge and optical measurement of an analyte with said cartridge |
| ES3009378T3 (en) | 2016-08-30 | 2025-03-26 | Outsense Diagnostics Ltd | Bodily emission analysis |
| WO2018128585A1 (en) * | 2017-01-04 | 2018-07-12 | Agency For Science, Technology And Research | Sieve-through vertical flow system for particle-based bioassays |
| CN111572053B (zh) * | 2020-05-29 | 2021-12-14 | 常州达姆斯检测技术有限公司 | 一种复合材料测试样条的加工方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4632901A (en) * | 1984-05-11 | 1986-12-30 | Hybritech Incorporated | Method and apparatus for immunoassays |
| US4965187A (en) * | 1986-09-10 | 1990-10-23 | Idexx Corporation | Method and apparatus for assaying whole blood |
| US5169789A (en) * | 1986-12-03 | 1992-12-08 | New Horizons Diagnostics Corporation | Device and method for self contained solid phase immunodiffusion assay |
| EP0301141A1 (en) * | 1987-07-30 | 1989-02-01 | Microbiological Research Corporation | Solid phase enzyme immunoassay test apparatus and process for detecting antibodies |
| US5006464A (en) * | 1987-10-01 | 1991-04-09 | E-Y Laboratories, Inc. | Directed flow diagnostic device and method |
| US4818677A (en) * | 1987-12-03 | 1989-04-04 | Monoclonal Antibodies, Inc. | Membrane assay using focused sample application |
| CA2017329A1 (en) * | 1989-05-26 | 1990-11-26 | Albert E. Chu | Elongated membrane flow-through diagnostic device and method |
| US5185127A (en) * | 1989-09-21 | 1993-02-09 | Becton, Dickinson And Company | Test device including flow control means |
| US5166051A (en) * | 1990-08-08 | 1992-11-24 | Genesis Labs, Inc. | Membranes, membrane overlays for exclusion of erythrocytes, and method for immunoassay of whole blood analytes |
| US5296192A (en) * | 1992-04-03 | 1994-03-22 | Home Diagnostics, Inc. | Diagnostic test strip |
| US5354692A (en) * | 1992-09-08 | 1994-10-11 | Pacific Biotech, Inc. | Analyte detection device including a hydrophobic barrier for improved fluid flow |
| US5500375A (en) * | 1993-04-13 | 1996-03-19 | Serex, Inc. | Integrated packaging-holder device for immunochromatographic assays in flow-through or dipstick formats |
-
1997
- 1997-03-25 US US08/823,936 patent/US5885526A/en not_active Expired - Lifetime
-
1998
- 1998-03-18 JP JP54579698A patent/JP4040110B2/ja not_active Expired - Fee Related
- 1998-03-18 CA CA002285048A patent/CA2285048C/en not_active Expired - Fee Related
- 1998-03-18 ES ES98910493T patent/ES2283050T3/es not_active Expired - Lifetime
- 1998-03-18 EP EP98910493A patent/EP0988546B1/en not_active Expired - Lifetime
- 1998-03-18 DE DE69837257T patent/DE69837257T2/de not_active Expired - Lifetime
- 1998-03-18 WO PCT/US1998/005373 patent/WO1998043083A1/en not_active Ceased
- 1998-03-18 CN CN98804585A patent/CN1125983C/zh not_active Expired - Fee Related
- 1998-03-18 AT AT98910493T patent/ATE356354T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998043083A1 (en) | 1998-10-01 |
| EP0988546A4 (en) | 2004-04-28 |
| JP2001525063A (ja) | 2001-12-04 |
| EP0988546A1 (en) | 2000-03-29 |
| CA2285048A1 (en) | 1998-10-01 |
| CN1256754A (zh) | 2000-06-14 |
| JP4040110B2 (ja) | 2008-01-30 |
| CA2285048C (en) | 2008-11-18 |
| CN1125983C (zh) | 2003-10-29 |
| ES2283050T3 (es) | 2007-10-16 |
| DE69837257D1 (de) | 2007-04-19 |
| EP0988546B1 (en) | 2007-03-07 |
| US5885526A (en) | 1999-03-23 |
| ATE356354T1 (de) | 2007-03-15 |
| HK1024743A1 (en) | 2000-10-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69837257T2 (de) | Analytische versuchsanordnung für auf membranen basierende versuche | |
| DE60003606T2 (de) | Immunochromatographisches Assay | |
| DE3851744T2 (de) | Membran-Untersuchung mit fokussierendem Probeauflegen. | |
| DE69921199T2 (de) | Zweirichtungsquerflussteststreifen und verfahren | |
| DE60219207T2 (de) | Diagnostisches testverfahren | |
| DE3887771T2 (de) | Immunoassays und Vorrichtungen dafür. | |
| DE3889833T2 (de) | Diagnostische Vorrichtung und Verfahren, gekennzeichnet durch einen gezielten Durchfluss. | |
| DE69732131T2 (de) | Immuno-Assay-Vorrichtung mit teilbarem Gehäuse | |
| DE3887941T2 (de) | Testvorrichtung mit mehrfachen Öffnungen. | |
| DE3852040T2 (de) | Vorrichtung und verfahren zur bestimmung einer komponente einer probe. | |
| DE69630295T2 (de) | Diagnostische vorrichtung und verfahren | |
| DE69226257T2 (de) | Vorrichtung zur antigen-bestimmung in kapillär-blut | |
| DE3851772T2 (de) | Einrichtung für Immunoassay. | |
| DE69708743T2 (de) | Verfahren und Vorrichtung zur Einschrittbestimmung von Vollblut | |
| DE69128618T3 (de) | Vorrichtung und verfahren zur ausführung von immunoassays | |
| DE69802412T2 (de) | Analytische Testvorrichtung und Verfahren zu ihren Verwendung | |
| DE69428798T2 (de) | Gerät für die medizinische diagnostik mit lateralem fluss und einer vorrichtung zur probenextraktion | |
| DE602004013147T2 (de) | Nativer analyt als referenz in lateralfluss-assays | |
| DE69227834T2 (de) | Testvorrichtung | |
| DE69906986T2 (de) | Analytisches testgerät und verfahren | |
| DE60223041T2 (de) | Diagnostiktestvorrichtung und verfahren | |
| DE3887491T2 (de) | Chromatographische Bindungstesteinrichtungen und Verfahren. | |
| DE3782597T2 (de) | Immunodiagnostische vorrichtung. | |
| DE69131933T2 (de) | Testvorrictung für Liganden-Rezeptor- Verfahren | |
| DE69231362T2 (de) | Gleichzeitiges testen von arzneimitteln und fingerabdrucktestverfahren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |