CA2285048C - Analytical device for membrane-based assays - Google Patents
Analytical device for membrane-based assays Download PDFInfo
- Publication number
- CA2285048C CA2285048C CA002285048A CA2285048A CA2285048C CA 2285048 C CA2285048 C CA 2285048C CA 002285048 A CA002285048 A CA 002285048A CA 2285048 A CA2285048 A CA 2285048A CA 2285048 C CA2285048 C CA 2285048C
- Authority
- CA
- Canada
- Prior art keywords
- reaction membrane
- support layer
- analytical device
- membrane
- top support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000012528 membrane Substances 0.000 title claims abstract description 187
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- FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 description 11
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- 239000003599 detergent Substances 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 230000003100 immobilizing effect Effects 0.000 description 3
- 239000002953 phosphate buffered saline Substances 0.000 description 3
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- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical class OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 2
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- SWGJCIMEBVHMTA-UHFFFAOYSA-K trisodium;6-oxido-4-sulfo-5-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2-sulfonate Chemical compound [Na+].[Na+].[Na+].C1=CC=C2C(N=NC3=C4C(=CC(=CC4=CC=C3O)S([O-])(=O)=O)S([O-])(=O)=O)=CC=C(S([O-])(=O)=O)C2=C1 SWGJCIMEBVHMTA-UHFFFAOYSA-K 0.000 description 2
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 2
- 229920002554 vinyl polymer Polymers 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229920002799 BoPET Polymers 0.000 description 1
- 241000701022 Cytomegalovirus Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000590002 Helicobacter pylori Species 0.000 description 1
- 239000005041 Mylar™ Substances 0.000 description 1
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- 210000004369 blood Anatomy 0.000 description 1
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- 229920002678 cellulose Polymers 0.000 description 1
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- 238000010276 construction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
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- 230000005012 migration Effects 0.000 description 1
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- 238000012986 modification Methods 0.000 description 1
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- 229920003052 natural elastomer Polymers 0.000 description 1
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- 239000013642 negative control Substances 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 230000009871 nonspecific binding Effects 0.000 description 1
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- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 230000007925 protein solubilization Effects 0.000 description 1
- 238000001799 protein solubilization Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
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- 238000012546 transfer Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54391—Immunochromatographic test strips based on vertical flow
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/823,936 | 1997-03-25 | ||
| US08/823,936 US5885526A (en) | 1997-03-25 | 1997-03-25 | Analytical device for membrane-based assays |
| PCT/US1998/005373 WO1998043083A1 (en) | 1997-03-25 | 1998-03-18 | Analytical device for membrane-based assays |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2285048A1 CA2285048A1 (en) | 1998-10-01 |
| CA2285048C true CA2285048C (en) | 2008-11-18 |
Family
ID=25240175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002285048A Expired - Fee Related CA2285048C (en) | 1997-03-25 | 1998-03-18 | Analytical device for membrane-based assays |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5885526A (https=) |
| EP (1) | EP0988546B1 (https=) |
| JP (1) | JP4040110B2 (https=) |
| CN (1) | CN1125983C (https=) |
| AT (1) | ATE356354T1 (https=) |
| CA (1) | CA2285048C (https=) |
| DE (1) | DE69837257T2 (https=) |
| ES (1) | ES2283050T3 (https=) |
| WO (1) | WO1998043083A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451607B1 (en) | 1998-05-07 | 2002-09-17 | Litmus Concepts, Inc. | External dried-reagent control for analytical test devices |
| US6171870B1 (en) * | 1998-08-06 | 2001-01-09 | Spectral Diagnostics, Inc. | Analytical test device and method for use in medical diagnoses |
| US6410341B1 (en) * | 1998-08-06 | 2002-06-25 | Spectral Diagnostics, Inc. | Analytical test device and method for use in medical diagnoses |
| US6214629B1 (en) * | 1998-08-06 | 2001-04-10 | Spectral Diagnostics, Inc. | Analytical test device and method for use in medical diagnoses |
| US7011940B1 (en) * | 1999-04-14 | 2006-03-14 | Medical Discovery Partners Llc | Quality control for cytochemical assays |
| US6281004B1 (en) * | 1999-04-14 | 2001-08-28 | Cytologix Corporation | Quality control for cytochemical assays |
| FR2792724B1 (fr) * | 1999-04-26 | 2001-05-25 | Biomerieux Sa | Dispositif de prelevement et de conservation d'un echantillon biologique et son procede de mise en oeuvre |
| JP2001083162A (ja) * | 1999-09-17 | 2001-03-30 | Fuji Photo Film Co Ltd | 膜状生体高分子吸着材及び吸着用キット |
| US6632681B1 (en) | 2000-07-24 | 2003-10-14 | Ey Laboratories | Reagent delivery device and method of use |
| US20030104492A1 (en) * | 2000-12-15 | 2003-06-05 | Albert Chu | Flow-through membrane assays for carbohydrates using labeled lectins |
| US20040241876A1 (en) * | 2000-12-22 | 2004-12-02 | France Fannes | Flow through assay device, diagnostic kit comprising said assay device and use of said assay device in the detection of an analyte present in a sample |
| US7087389B2 (en) | 2001-02-09 | 2006-08-08 | Council Of Scientific & Industrial Research | Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity |
| US7531362B2 (en) | 2001-06-07 | 2009-05-12 | Medmira Inc. | Rapid diagnostic assay |
| US7205159B2 (en) * | 2001-08-20 | 2007-04-17 | Proteome Systems Intellectual Property Pty Ltd. | Diagnostic testing process and apparatus |
| WO2003016902A1 (en) * | 2001-08-20 | 2003-02-27 | Proteome Systems Intellectual Property Pty Ltd | Diagnostic testing process and apparatus |
| ATE358274T1 (de) * | 2001-12-12 | 2007-04-15 | Proteome Systems Intellectual | Diagnostisches testverfahren |
| WO2003098215A1 (en) * | 2002-05-16 | 2003-11-27 | Medmira Inc. | Rapid vaccinia antibody detection device, method and test kit |
| US20060205086A1 (en) * | 2002-10-24 | 2006-09-14 | Spectral Diagnostics Inc. | Diagnostic device |
| US7256053B2 (en) * | 2002-10-24 | 2007-08-14 | Nanogen, Inc. | Diagnostic device for analyte detection |
| US7488450B2 (en) * | 2004-03-04 | 2009-02-10 | Beckman Coulter, Inc. | Analyte collection and detection devices |
| FR2872288B1 (fr) * | 2004-06-28 | 2007-08-03 | Biomerieux Sa | Dispositif d'analyse integre, adaptable sur un conteneur d'un echantillon a analyser |
| US20060019406A1 (en) * | 2004-07-23 | 2006-01-26 | Ning Wei | Lateral flow device for the detection of large pathogens |
| US20060068500A1 (en) * | 2004-09-28 | 2006-03-30 | Kimberly-Clark Worldwide, Inc. | Detecting yeast infections using a lateral flow assay |
| DK1843850T3 (en) | 2005-01-31 | 2015-12-07 | Realbio Technologies Ltd | LATERAL FLOW STEERING CAPILLAR DEVICE |
| US7189522B2 (en) | 2005-03-11 | 2007-03-13 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
| WO2006098804A2 (en) * | 2005-03-11 | 2006-09-21 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
| US20070141723A1 (en) * | 2005-12-16 | 2007-06-21 | Sompuram Seshi A | Immunohistochemistry staining controls |
| JP4860489B2 (ja) * | 2007-01-09 | 2012-01-25 | 浜松ホトニクス株式会社 | 免疫クロマト試験片の測定方法 |
| US7816090B2 (en) * | 2007-01-10 | 2010-10-19 | Ortho-Clinical Diagnostics, Inc. | Multiple immunochemistry assays on an element |
| EP2012126A1 (en) * | 2007-07-04 | 2009-01-07 | Koninklijke Philips Electronics N.V. | Porous biological assay substrate and method for producing such substrate |
| CN101603967B (zh) * | 2008-06-10 | 2015-02-18 | 英科新创(厦门)科技有限公司 | 快速检测人ABO/Rh/MN血型的方法及试剂盒 |
| WO2010007613A1 (en) | 2008-06-29 | 2010-01-21 | Realbio Technologies Ltd. | Liquid–transfer device particularly useful as a capturing device in a biological assay process |
| US20100022916A1 (en) | 2008-07-24 | 2010-01-28 | Javanbakhsh Esfandiari | Method and Apparatus for Collecting and Preparing Biological Samples for Testing |
| US8603835B2 (en) | 2011-02-10 | 2013-12-10 | Chembio Diagnostic Systems, Inc. | Reduced step dual path immunoassay device and method |
| US20130164193A1 (en) | 2011-12-22 | 2013-06-27 | Life Technologies Corporation | Sequential lateral flow capillary device for analyte determination |
| DK3578635T3 (da) | 2014-04-02 | 2022-02-07 | Chembio Diagnostic Systems Inc | Immunoassay, som anvender indfangningskonjugat |
| US9568404B2 (en) | 2014-05-16 | 2017-02-14 | Junyu Mai | Method and apparatus for biomolecule analysis |
| US20160116466A1 (en) | 2014-10-27 | 2016-04-28 | Chembio Diagnostic Systems, Inc. | Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses |
| EP3427049A4 (en) * | 2016-03-07 | 2019-10-16 | Nanodx Healthcare Pvt. Ltd. | ASSAY AND KITS FOR DETECTING ENDOTOXIN |
| EP4023338B1 (en) | 2016-04-14 | 2024-10-02 | Roche Diagnostics GmbH | Cartridge and optical measurement of an analyte with said cartridge |
| ES3009378T3 (en) | 2016-08-30 | 2025-03-26 | Outsense Diagnostics Ltd | Bodily emission analysis |
| WO2018128585A1 (en) * | 2017-01-04 | 2018-07-12 | Agency For Science, Technology And Research | Sieve-through vertical flow system for particle-based bioassays |
| CN111572053B (zh) * | 2020-05-29 | 2021-12-14 | 常州达姆斯检测技术有限公司 | 一种复合材料测试样条的加工方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4632901A (en) * | 1984-05-11 | 1986-12-30 | Hybritech Incorporated | Method and apparatus for immunoassays |
| US4965187A (en) * | 1986-09-10 | 1990-10-23 | Idexx Corporation | Method and apparatus for assaying whole blood |
| US5169789A (en) * | 1986-12-03 | 1992-12-08 | New Horizons Diagnostics Corporation | Device and method for self contained solid phase immunodiffusion assay |
| EP0301141A1 (en) * | 1987-07-30 | 1989-02-01 | Microbiological Research Corporation | Solid phase enzyme immunoassay test apparatus and process for detecting antibodies |
| US5006464A (en) * | 1987-10-01 | 1991-04-09 | E-Y Laboratories, Inc. | Directed flow diagnostic device and method |
| US4818677A (en) * | 1987-12-03 | 1989-04-04 | Monoclonal Antibodies, Inc. | Membrane assay using focused sample application |
| CA2017329A1 (en) * | 1989-05-26 | 1990-11-26 | Albert E. Chu | Elongated membrane flow-through diagnostic device and method |
| US5185127A (en) * | 1989-09-21 | 1993-02-09 | Becton, Dickinson And Company | Test device including flow control means |
| US5166051A (en) * | 1990-08-08 | 1992-11-24 | Genesis Labs, Inc. | Membranes, membrane overlays for exclusion of erythrocytes, and method for immunoassay of whole blood analytes |
| US5296192A (en) * | 1992-04-03 | 1994-03-22 | Home Diagnostics, Inc. | Diagnostic test strip |
| US5354692A (en) * | 1992-09-08 | 1994-10-11 | Pacific Biotech, Inc. | Analyte detection device including a hydrophobic barrier for improved fluid flow |
| US5500375A (en) * | 1993-04-13 | 1996-03-19 | Serex, Inc. | Integrated packaging-holder device for immunochromatographic assays in flow-through or dipstick formats |
-
1997
- 1997-03-25 US US08/823,936 patent/US5885526A/en not_active Expired - Lifetime
-
1998
- 1998-03-18 JP JP54579698A patent/JP4040110B2/ja not_active Expired - Fee Related
- 1998-03-18 CA CA002285048A patent/CA2285048C/en not_active Expired - Fee Related
- 1998-03-18 ES ES98910493T patent/ES2283050T3/es not_active Expired - Lifetime
- 1998-03-18 EP EP98910493A patent/EP0988546B1/en not_active Expired - Lifetime
- 1998-03-18 DE DE69837257T patent/DE69837257T2/de not_active Expired - Lifetime
- 1998-03-18 WO PCT/US1998/005373 patent/WO1998043083A1/en not_active Ceased
- 1998-03-18 CN CN98804585A patent/CN1125983C/zh not_active Expired - Fee Related
- 1998-03-18 AT AT98910493T patent/ATE356354T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998043083A1 (en) | 1998-10-01 |
| EP0988546A4 (en) | 2004-04-28 |
| JP2001525063A (ja) | 2001-12-04 |
| EP0988546A1 (en) | 2000-03-29 |
| CA2285048A1 (en) | 1998-10-01 |
| DE69837257T2 (de) | 2007-11-08 |
| CN1256754A (zh) | 2000-06-14 |
| JP4040110B2 (ja) | 2008-01-30 |
| CN1125983C (zh) | 2003-10-29 |
| ES2283050T3 (es) | 2007-10-16 |
| DE69837257D1 (de) | 2007-04-19 |
| EP0988546B1 (en) | 2007-03-07 |
| US5885526A (en) | 1999-03-23 |
| ATE356354T1 (de) | 2007-03-15 |
| HK1024743A1 (en) | 2000-10-20 |
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| MKLA | Lapsed |
Effective date: 20170320 |