DE69831007T2 - Humane checkpointkinase, hcds1, zusammensetzungen und verfahren - Google Patents

Humane checkpointkinase, hcds1, zusammensetzungen und verfahren Download PDF

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Publication number
DE69831007T2
DE69831007T2 DE69831007T DE69831007T DE69831007T2 DE 69831007 T2 DE69831007 T2 DE 69831007T2 DE 69831007 T DE69831007 T DE 69831007T DE 69831007 T DE69831007 T DE 69831007T DE 69831007 T2 DE69831007 T2 DE 69831007T2
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DE
Germany
Prior art keywords
nucleic acid
protein
hcds1
seq
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831007T
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German (de)
English (en)
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DE69831007D1 (de
Inventor
H. Walter LUYTEN
E. Andrew Macclesfield PARKER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
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Janssen Pharmaceutica NV
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Publication of DE69831007D1 publication Critical patent/DE69831007D1/de
Publication of DE69831007T2 publication Critical patent/DE69831007T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE69831007T 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren Expired - Lifetime DE69831007T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9722320 1997-10-22
GBGB9722320.0A GB9722320D0 (en) 1997-10-22 1997-10-22 Human cell cycle checkpoint proteins
PCT/EP1998/006982 WO1999020747A2 (en) 1997-10-22 1998-10-21 HUMAN CHECKPOINT KINASE, hCDS1, COMPOSITIONS AND METHODS

Publications (2)

Publication Number Publication Date
DE69831007D1 DE69831007D1 (de) 2005-09-01
DE69831007T2 true DE69831007T2 (de) 2006-04-20

Family

ID=10820925

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69831007T Expired - Lifetime DE69831007T2 (de) 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren
DE69831500T Expired - Lifetime DE69831500T2 (de) 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69831500T Expired - Lifetime DE69831500T2 (de) 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren

Country Status (13)

Country Link
US (4) US6413755B1 (https=)
EP (2) EP1025236B1 (https=)
JP (2) JP4261050B2 (https=)
AT (2) ATE300619T1 (https=)
AU (2) AU760544B2 (https=)
CA (2) CA2306492C (https=)
DE (2) DE69831007T2 (https=)
DK (2) DK1025237T3 (https=)
ES (2) ES2245807T3 (https=)
GB (1) GB9722320D0 (https=)
IL (2) IL135687A (https=)
NZ (2) NZ503983A (https=)
WO (2) WO1999020747A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins
AU4289599A (en) * 1998-06-23 2000-01-10 Chugai Seiyaku Kabushiki Kaisha Cell cycle regulatory factor
GB9827430D0 (en) * 1998-12-11 1999-02-03 Ludwig Inst Cancer Res Differential expression in primary breast cancer
AU783686B2 (en) * 2000-02-18 2005-11-24 Lexicon Pharmaceuticals, Inc. Human kinases and polynucleotides encoding the same
EP1265992A2 (en) * 2000-03-08 2002-12-18 Zealand Pharma A/S Materials and methods relating to the degradation of cdc25a in response to dna damage
AU2001255573A1 (en) * 2000-04-20 2001-11-07 Incyte Genomics, Inc. Human kinases
US6323016B1 (en) 2000-06-09 2001-11-27 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
FR2812945B1 (fr) * 2000-08-10 2002-10-04 Aventis Pharma Sa Utilisation de la proteine grf1 et cellules exprimant la proteine grf1 pour le criblage de molecules
US6372468B1 (en) * 2000-09-14 2002-04-16 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
CA2439800A1 (en) * 2000-12-14 2002-06-20 Pe Corporation (Ny) Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof
WO2002051858A2 (en) * 2000-12-22 2002-07-04 Isis Pharmaceuticals, Inc. Antisense modulation of chk2 expression
US6451538B1 (en) * 2000-12-22 2002-09-17 Isis Pharmaceuticals, Inc. Antisense modulation of CHK2 expression
AU2002246858A1 (en) 2000-12-27 2002-08-06 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
EP1224942A1 (en) * 2001-01-23 2002-07-24 Bernhard Dr. Nieswandt Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases
CA2512683C (en) * 2003-01-09 2010-03-16 Pfizer Inc. Tricyclic compounds protein kinase inhibitors for enhancing the efficacy of anti-neoplastic agents and radiation therapy
EP1660504B1 (en) * 2003-08-29 2008-10-29 Pfizer Inc. Thienopyridine-phenylacet amides and their derivatives useful as new anti-angiogenic agents
EP1660503A1 (en) * 2003-08-29 2006-05-31 Pfizer Inc. Naphthalene carboxamides and their derivatives useful as new anti-angiogenic agents
US8572169B2 (en) * 2006-08-28 2013-10-29 Myspace, Llc System, apparatus and method for discovery of music within a social network
EP2409700A1 (en) 2007-05-08 2012-01-25 Schering Corporation Methods of treatment using intravenous formulations comprising temozolomide
ES2378513T3 (es) * 2008-08-06 2012-04-13 Pfizer Inc. Compuestos 2-heterociclilamino piracinas sustituidas en posición 6 como inhibidores de CHK-1

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443962A (en) * 1993-06-04 1995-08-22 Mitotix, Inc. Methods of identifying inhibitors of cdc25 phosphatase
US5674748A (en) * 1995-03-14 1997-10-07 Thomas Jefferson University Human cyclin-dependent kinase-like proteins and methods of using the same
IL121306A0 (en) * 1995-11-16 1998-01-04 Icos Corp Cell cycle checkpoint pik-related kinase materials and methods
US5744349A (en) * 1996-03-05 1998-04-28 Washington University DNA sequences encoding human Myt1 kinase
US6218109B1 (en) * 1997-09-05 2001-04-17 Baylor College Of Medicine Mammalian checkpoint genes and proteins
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins

Also Published As

Publication number Publication date
ATE304052T1 (de) 2005-09-15
DE69831500T2 (de) 2006-06-14
JP2001523461A (ja) 2001-11-27
WO1999020747A2 (en) 1999-04-29
JP4261050B2 (ja) 2009-04-30
IL135688A0 (en) 2001-05-20
US6943013B2 (en) 2005-09-13
AU752617B2 (en) 2002-09-26
US6413755B1 (en) 2002-07-02
ES2245050T3 (es) 2005-12-16
ATE300619T1 (de) 2005-08-15
US6531312B1 (en) 2003-03-11
DE69831007D1 (de) 2005-09-01
EP1025236B1 (en) 2005-07-27
DE69831500D1 (de) 2005-10-13
NZ503983A (en) 2002-03-28
NZ503965A (en) 2002-03-28
US20050180981A1 (en) 2005-08-18
IL135688A (en) 2010-04-29
AU760544B2 (en) 2003-05-15
JP4418103B2 (ja) 2010-02-17
US7414020B2 (en) 2008-08-19
US20030017160A1 (en) 2003-01-23
AU2612699A (en) 1999-06-07
EP1025237B1 (en) 2005-09-07
WO1999020747A3 (en) 1999-07-01
IL135687A0 (en) 2001-05-20
CA2306492A1 (en) 1999-05-27
DK1025236T3 (da) 2005-10-24
EP1025236A2 (en) 2000-08-09
JP2001520037A (ja) 2001-10-30
CA2306492C (en) 2014-03-25
EP1025237A2 (en) 2000-08-09
DK1025237T3 (da) 2005-11-28
WO1999025843A3 (en) 1999-08-05
AU1232299A (en) 1999-05-10
GB9722320D0 (en) 1997-12-17
CA2308013A1 (en) 1999-04-29
ES2245807T3 (es) 2006-01-16
WO1999025843A2 (en) 1999-05-27
IL135687A (en) 2007-07-04

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