DE69812957T2 - Verfahren zur herstellung von 1,3-diaza-spiro[4.4]non-1-en-4-on derivaten und 1-cyano-1-acylaminocyclopentan zwischenprodukte - Google Patents

Verfahren zur herstellung von 1,3-diaza-spiro[4.4]non-1-en-4-on derivaten und 1-cyano-1-acylaminocyclopentan zwischenprodukte

Info

Publication number
DE69812957T2
DE69812957T2 DE69812957T DE69812957T DE69812957T2 DE 69812957 T2 DE69812957 T2 DE 69812957T2 DE 69812957 T DE69812957 T DE 69812957T DE 69812957 T DE69812957 T DE 69812957T DE 69812957 T2 DE69812957 T2 DE 69812957T2
Authority
DE
Germany
Prior art keywords
formula
compound
preparation
transformed
acylaminocyclopentane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69812957T
Other languages
English (en)
Other versions
DE69812957D1 (de
Inventor
Csaba Huszar
Attila Kis-Tamas
Attila Nemeth
Zsuzsanna Nad
Zoltan Makovi
Antal Gajary
Endre Kollar
Peter Aranyosi
Karoly Gyuere
Istvan Meszaros
Hari Zsuzsanna Csetrin
Attila Supic
Zrinyi Ilona Dervalicsne
Katalin Dubovszki
Lajosne Pali
Karasz Agnes Kunsztn
Erzsebet Bognar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Application granted granted Critical
Publication of DE69812957D1 publication Critical patent/DE69812957D1/de
Publication of DE69812957T2 publication Critical patent/DE69812957T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69812957T 1997-07-25 1998-07-22 Verfahren zur herstellung von 1,3-diaza-spiro[4.4]non-1-en-4-on derivaten und 1-cyano-1-acylaminocyclopentan zwischenprodukte Expired - Lifetime DE69812957T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP9701295A HU218680B (hu) 1997-07-25 1997-07-25 Eljárás 1,3-diaza-spiro[4,4]non-1-én-4-on-származékok előállítására és 1-ciano-1-(acil-amino)-ciklopentán intermedierek
PCT/HU1998/000068 WO1999005120A1 (en) 1997-07-25 1998-07-22 Process for the preparation of 1,3-diaza-spiro (4.4) non-1-en-4-one derivatives and 1-cyano-1-acylaminocyclopentane intermediates

Publications (2)

Publication Number Publication Date
DE69812957D1 DE69812957D1 (de) 2003-05-08
DE69812957T2 true DE69812957T2 (de) 2003-12-04

Family

ID=89995421

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69812957T Expired - Lifetime DE69812957T2 (de) 1997-07-25 1998-07-22 Verfahren zur herstellung von 1,3-diaza-spiro[4.4]non-1-en-4-on derivaten und 1-cyano-1-acylaminocyclopentan zwischenprodukte

Country Status (12)

Country Link
US (1) US6211382B1 (de)
EP (1) EP0998463B1 (de)
JP (1) JP4322420B2 (de)
AT (1) ATE236132T1 (de)
AU (1) AU8553798A (de)
BR (1) BR9811481B1 (de)
CA (1) CA2297189C (de)
DE (1) DE69812957T2 (de)
ES (1) ES2193548T3 (de)
HU (1) HU218680B (de)
NO (1) NO315157B1 (de)
WO (1) WO1999005120A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101704788B (zh) * 2009-11-12 2011-09-07 苏州雅本化学股份有限公司 2-丁基-1,3-二氮杂螺环[4.4]壬烷-1-烯-4-酮的制备方法
JP6202935B2 (ja) * 2013-08-21 2017-09-27 株式会社東芝 原子炉圧力容器
JP6950676B2 (ja) * 2016-03-15 2021-10-13 アステラス製薬株式会社 錠剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2681067B1 (fr) * 1991-09-10 1993-12-17 Elf Sanofi Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
US5541209A (en) 1994-08-22 1996-07-30 Bristol-Myers Squibb Company Method of treating or preventing cardiac arrhythmia employing an N-substituted heterocyclic derivative
AU5843996A (en) * 1995-05-31 1996-12-18 Ihara Chemical Industry Co. Ltd. Phenylalkanamide derivatives and agrohorticultural bacterici des
CA2196263C (en) * 1996-02-09 2004-10-26 Barry Jackson Process for the preparation of 4-oxoimidazolinium salts
ES2259804T3 (es) * 1996-04-02 2006-10-16 Bayer Cropscience Ag Fenilcetoenoles sustituidos como pesticidas y herbicidas.
US6162922A (en) * 1998-01-30 2000-12-19 Bristol-Myers Squibb Co. Method for preparing N-substituted heterocyclic derivatives using a phase-transfer catalyst
DE19912383A1 (de) * 1998-03-27 1999-09-30 Degussa Verfahren zur Herstellung von cyclischen 4-Oxoamidinen
US5910595A (en) * 1998-06-26 1999-06-08 Salsbury Chemicals, Inc. Process for preparing oximidazoles

Also Published As

Publication number Publication date
ES2193548T3 (es) 2003-11-01
NO315157B1 (no) 2003-07-21
HU218680A (en) 2000-10-28
HU9701295D0 (en) 1997-09-29
US6211382B1 (en) 2001-04-03
EP0998463B1 (de) 2003-04-02
BR9811481A (pt) 2000-09-19
CA2297189C (en) 2007-08-28
DE69812957D1 (de) 2003-05-08
JP2001510830A (ja) 2001-08-07
AU8553798A (en) 1999-02-16
NO20000344D0 (no) 2000-01-24
WO1999005120A1 (en) 1999-02-04
CA2297189A1 (en) 1999-02-04
EP0998463A1 (de) 2000-05-10
NO20000344L (no) 2000-03-22
HU218680B (hu) 2000-10-30
ATE236132T1 (de) 2003-04-15
BR9811481B1 (pt) 2010-10-05
JP4322420B2 (ja) 2009-09-02

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