DE69726672T2 - Polyätherester-Copolymere als Matrixmaterialien für die Arzneistoffabgabe - Google Patents

Polyätherester-Copolymere als Matrixmaterialien für die Arzneistoffabgabe Download PDF

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Publication number
DE69726672T2
DE69726672T2 DE69726672T DE69726672T DE69726672T2 DE 69726672 T2 DE69726672 T2 DE 69726672T2 DE 69726672 T DE69726672 T DE 69726672T DE 69726672 T DE69726672 T DE 69726672T DE 69726672 T2 DE69726672 T2 DE 69726672T2
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DE
Germany
Prior art keywords
drug delivery
matrix materials
polyetherester copolymers
polyetherester
glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69726672T
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English (en)
Other versions
DE69726672D1 (de
Inventor
Jacob Hillebrand Goedemoed
Wilhelmus Everhardus Hennink
Jeroen Mattijs Bezemer
Jan Feijen
Blitterswijk Clemens Anton Van
Bruijn Joost Dick De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Octoplus Polyactive Sciences Bv Leiden Nl
OctoPlus Sciences BV
Biolex Therapeutics Inc
Original Assignee
Chienna BV
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Filing date
Publication date
Application filed by Chienna BV filed Critical Chienna BV
Publication of DE69726672D1 publication Critical patent/DE69726672D1/de
Application granted granted Critical
Publication of DE69726672T2 publication Critical patent/DE69726672T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69726672T 1996-08-16 1997-08-18 Polyätherester-Copolymere als Matrixmaterialien für die Arzneistoffabgabe Expired - Lifetime DE69726672T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/699,896 US5980948A (en) 1996-08-16 1996-08-16 Polyetherester copolymers as drug delivery matrices

Publications (2)

Publication Number Publication Date
DE69726672D1 DE69726672D1 (de) 2004-01-22
DE69726672T2 true DE69726672T2 (de) 2004-10-07

Family

ID=24811379

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69729228T Expired - Lifetime DE69729228T2 (de) 1996-08-16 1997-08-18 Polyetherester-Copolymere als Matrixmaterial für die Arzneistoffabgabe
DE69726672T Expired - Lifetime DE69726672T2 (de) 1996-08-16 1997-08-18 Polyätherester-Copolymere als Matrixmaterialien für die Arzneistoffabgabe

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69729228T Expired - Lifetime DE69729228T2 (de) 1996-08-16 1997-08-18 Polyetherester-Copolymere als Matrixmaterial für die Arzneistoffabgabe

Country Status (9)

Country Link
US (1) US5980948A (de)
EP (2) EP0830859B1 (de)
AT (2) ATE255884T1 (de)
CA (1) CA2213368C (de)
DE (2) DE69729228T2 (de)
DK (2) DK1247522T3 (de)
ES (2) ES2221916T3 (de)
PT (2) PT830859E (de)
WO (1) WO1998006439A1 (de)

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US5980948A (en) 1999-11-09
DK0830859T3 (da) 2004-04-05
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CA2213368C (en) 2008-04-01
ATE267006T1 (de) 2004-06-15
DE69726672D1 (de) 2004-01-22
ATE255884T1 (de) 2003-12-15
DE69729228T2 (de) 2005-05-04
WO1998006439A1 (en) 1998-02-19
CA2213368A1 (en) 1998-02-16
EP0830859A2 (de) 1998-03-25
DE69729228D1 (de) 2004-06-24
ES2212037T3 (es) 2004-07-16
EP1247522A1 (de) 2002-10-09
DK1247522T3 (da) 2004-09-27
PT830859E (pt) 2004-04-30
ES2221916T3 (es) 2005-01-16
EP1247522B1 (de) 2004-05-19

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