DE69726449D1 - Aminophosphonsäure-derivate als arzneimittel - Google Patents

Aminophosphonsäure-derivate als arzneimittel

Info

Publication number
DE69726449D1
DE69726449D1 DE69726449T DE69726449T DE69726449D1 DE 69726449 D1 DE69726449 D1 DE 69726449D1 DE 69726449 T DE69726449 T DE 69726449T DE 69726449 T DE69726449 T DE 69726449T DE 69726449 D1 DE69726449 D1 DE 69726449D1
Authority
DE
Germany
Prior art keywords
aminophosphonsäure
als arzneimittel
derivate
derivate als
arzneimittel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69726449T
Other languages
English (en)
Other versions
DE69726449T2 (de
Inventor
Mong Nguyen
Trung Phan
Diep Vinh Van
Simon Floret
Raymond Azoulay
Eric Niesor
Leigh Bentzen
John Ife
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IIEX PRODUCTS,INC., SAN ANTONIO, TEX., US
Original Assignee
Ilex Oncology Research SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ilex Oncology Research SARL filed Critical Ilex Oncology Research SARL
Publication of DE69726449D1 publication Critical patent/DE69726449D1/de
Application granted granted Critical
Publication of DE69726449T2 publication Critical patent/DE69726449T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69726449T 1996-12-20 1997-12-17 Aminophosphonsäure-derivate als arzneimittel Expired - Fee Related DE69726449T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9626615.0A GB9626615D0 (en) 1996-12-20 1996-12-20 Novel compounds
GB9626615 1996-12-20
PCT/EP1997/007161 WO1998028310A1 (en) 1996-12-20 1997-12-17 Pharmaceutical aminophosphonic acid derivatives

Publications (2)

Publication Number Publication Date
DE69726449D1 true DE69726449D1 (en) 2004-01-08
DE69726449T2 DE69726449T2 (de) 2004-08-26

Family

ID=10804837

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69726449T Expired - Fee Related DE69726449T2 (de) 1996-12-20 1997-12-17 Aminophosphonsäure-derivate als arzneimittel

Country Status (31)

Country Link
US (2) US6303784B1 (de)
EP (1) EP0946572B1 (de)
JP (1) JP2001506667A (de)
KR (1) KR20000069609A (de)
CN (1) CN1105117C (de)
AP (1) AP9901546A0 (de)
AR (1) AR008541A1 (de)
AT (1) ATE255117T1 (de)
AU (1) AU5858898A (de)
BG (1) BG103574A (de)
BR (1) BR9714650A (de)
CA (1) CA2275696A1 (de)
CO (1) CO4930276A1 (de)
DE (1) DE69726449T2 (de)
DZ (1) DZ2377A1 (de)
EA (1) EA199900580A1 (de)
GB (1) GB9626615D0 (de)
HU (1) HUP0002171A3 (de)
ID (1) ID22053A (de)
IL (1) IL130334A0 (de)
MA (1) MA24427A1 (de)
NO (1) NO993001L (de)
NZ (1) NZ335884A (de)
OA (1) OA11068A (de)
PE (1) PE46799A1 (de)
PL (1) PL334189A1 (de)
SK (1) SK81099A3 (de)
TR (1) TR199901423T2 (de)
TW (1) TW434221B (de)
WO (1) WO1998028310A1 (de)
ZA (1) ZA9711431B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK287296B6 (sk) 2000-02-16 2010-06-07 Smithkline Beecham Plc Pyrimidín-4-ónové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie
EP1531157B1 (de) * 2000-02-29 2008-03-19 Medicure International Inc. Cardioprotektive Phosphonate
ATE293119T1 (de) * 2000-02-29 2005-04-15 Medicure Int Inc Cardioprotektive phosphonate
JP2004513891A (ja) * 2000-09-27 2004-05-13 アイレックス　オンコロジー　リサーチ　エス．エイ． α−置換β−アミノエチルホスホネート
US20030114421A1 (en) * 2000-09-27 2003-06-19 Phan Hieu Trung Alpha-substituted beta-aminoethyl phosphonate derivatives
GB0024808D0 (en) 2000-10-10 2000-11-22 Smithkline Beecham Plc Novel compounds
GB0025849D0 (en) * 2000-10-23 2000-12-06 Smithkline Beecham Plc Novel compounds
JP2005529071A (ja) * 2002-02-11 2005-09-29 アイレツクス・プロダクツ・インコーポレイテツド α−置換ヘテロアリールアルキルホスホン酸エステル誘導体
WO2003070169A2 (en) * 2002-02-19 2003-08-28 Ilex Products, Inc. Aminodiphosphonate apolipoprotein e modulators
JP4824968B2 (ja) * 2005-08-18 2011-11-30 株式会社クレハ ホスホン酸誘導体及びその酸付加塩、並びにそれを用いた農園芸用病害防除剤
EP2649053B1 (de) 2010-12-06 2015-11-04 Glaxo Group Limited Pyrimidinonverbindungen zur verwendung bei der behandlung von durch lp-pla2 bedingten krankheiten oder zuständen
EP2739627A4 (de) 2011-07-27 2015-01-21 Glaxo Group Ltd 2,3-dihydroimidazo-[1,2-c-] pyrimidin-5 (1h)-on-verbindungen als lp-pla²- inhibitoren
KR20140059204A (ko) 2011-07-27 2014-05-15 글락소 그룹 리미티드 비시클릭 피리미돈 화합물
LT2751094T (lt) 2011-09-01 2018-11-12 Glaxo Group Limited Naujoji kristalinė forma
EP2948457A4 (de) 2013-01-25 2016-09-07 Glaxosmithkline Ip Dev Ltd Verbindungen
WO2014114694A1 (en) 2013-01-25 2014-07-31 Glaxosmithkline Intellectual Property Development Limited 2,3-dihydroimidazol[1,2-c]pyrimidin-5(1h)-one based lipoprotein-associated phospholipase a2 (lp-pla2) inhibitors
AU2014210260B2 (en) 2013-01-25 2016-08-04 Glaxosmithkline Intellectual Property Development Limited Bicyclic pyrimidone compounds as inhibitors of Lp-PLA2
WO2016012916A1 (en) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2
WO2016012917A1 (en) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2
MX2022005615A (es) 2019-11-09 2022-07-27 Shanghai Simr Biotechnology Co Ltd Derivado triciclico de dihidroimidazopirimidona, metodo de preparacion del mismo, composicion farmaceutica y uso del mismo.
CN115304620A (zh) 2021-05-07 2022-11-08 上海赛默罗生物科技有限公司 嘧啶酮衍生物、其制备方法、药物组合物和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH683996A5 (fr) 1992-03-05 1994-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et compositions pharmaceutiques les contenant.
DE4433244A1 (de) * 1994-09-19 1996-03-28 Hoechst Ag Aminomethylphosphon- und Aminomethylphosphinsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen
CH690264A5 (fr) 1995-06-30 2000-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et leur utilisation pour la préparation de compositions pharmaceutiques.
GB9626536D0 (en) 1996-12-20 1997-02-05 Symphar Sa Novel compounds

Also Published As

Publication number Publication date
MA24427A1 (fr) 1998-07-01
HUP0002171A3 (en) 2002-12-28
ID22053A (id) 1999-08-26
PE46799A1 (es) 1999-06-24
EP0946572B1 (de) 2003-11-26
CO4930276A1 (es) 2000-06-27
AU5858898A (en) 1998-07-17
DE69726449T2 (de) 2004-08-26
CA2275696A1 (en) 1998-07-02
ZA9711431B (en) 1999-06-21
GB9626615D0 (en) 1997-02-05
JP2001506667A (ja) 2001-05-22
SK81099A3 (en) 1999-11-08
KR20000069609A (ko) 2000-11-25
CN1105117C (zh) 2003-04-09
OA11068A (en) 2003-03-10
TW434221B (en) 2001-05-16
WO1998028310A1 (en) 1998-07-02
NZ335884A (en) 2000-11-24
CN1240451A (zh) 2000-01-05
AR008541A1 (es) 2000-01-19
IL130334A0 (en) 2000-06-01
ATE255117T1 (de) 2003-12-15
US6303784B1 (en) 2001-10-16
BG103574A (bg) 2000-11-30
TR199901423T2 (xx) 1999-10-21
HUP0002171A2 (hu) 2001-05-28
BR9714650A (pt) 2000-10-03
PL334189A1 (en) 2000-02-14
NO993001D0 (no) 1999-06-18
EA199900580A1 (ru) 1999-12-29
EP0946572A1 (de) 1999-10-06
DZ2377A1 (fr) 2002-12-28
US20020082423A1 (en) 2002-06-27
NO993001L (no) 1999-06-18
AP9901546A0 (en) 1999-06-30

Similar Documents

Publication Publication Date Title
DE69634986D1 (en) Modulares wandlersystem
DE59704951D1 (en) Plättchenförmiges titandioxidpigment
DE69608577D1 (en) Thermostabiler schalldämmstoff
DE69702926D1 (en) Polyurethanhartschäume
DE69705420D1 (en) Polyurethanhartschäume
DE59705192D1 (en) Lcp-blends
DE69726449D1 (en) Aminophosphonsäure-derivate als arzneimittel
DE59711450D1 (en) Arylalkanoylpyridazine
DE59700372D1 (en) Blockcopolymere
DE69703480D1 (en) Anionische photokatalysator
DE69717494D1 (en) Shampoo
EP0866961A4 (de) Verbessertes spektrophotometer
DE69621466D1 (en) Thermoplastische hydroxy-phenoxyetherpolymerverbundwerkstoffe
DE69706823D1 (en) Bicyclische 4-aralkylaminopyrimidin-derivate als tyrosinkinase-inhibitoren
DE59707730D1 (en) Peripheralpumpe
DE59703905D1 (en) Linearmotorgetriebene transportanlage
DE59704086D1 (en) Twin-dualmode-filter
HU9701631D0 (en) Compact oil-cut-device
DE69717811D1 (en) Substituierte phenethyl-derivate als matrx-metalloprotease-inhibitoren
DE59903329D1 (en) Phosphin- und phosphonsäurederivate als arzneimittel
DE59703023D1 (en) Cyclopeptidderivate
DE59711583D1 (en) Heterocyclyluracile
DE59702027D1 (en) Bragg-modulator
DE59709914D1 (en) Substituierte aromatische phosphonsäurederivate
DE59705556D1 (en) Peripheralpumpe

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: IIEX PRODUCTS,INC., SAN ANTONIO, TEX., US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee