DE69721838D1 - 1-[1-(4-chlorphenyl)cyclobutyl]-3-methylbutyl amin derivate zur senkung von harnsäurespiegeln beim menschen - Google Patents

1-[1-(4-chlorphenyl)cyclobutyl]-3-methylbutyl amin derivate zur senkung von harnsäurespiegeln beim menschen

Info

Publication number
DE69721838D1
DE69721838D1 DE69721838T DE69721838T DE69721838D1 DE 69721838 D1 DE69721838 D1 DE 69721838D1 DE 69721838 T DE69721838 T DE 69721838T DE 69721838 T DE69721838 T DE 69721838T DE 69721838 D1 DE69721838 D1 DE 69721838D1
Authority
DE
Germany
Prior art keywords
humans
pct
cyclobutyl
chlorphenyl
reduction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69721838T
Other languages
English (en)
Other versions
DE69721838T2 (de
Inventor
Finian Kelly
Paul Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Abbott GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott GmbH and Co KG filed Critical Abbott GmbH and Co KG
Publication of DE69721838D1 publication Critical patent/DE69721838D1/de
Application granted granted Critical
Publication of DE69721838T2 publication Critical patent/DE69721838T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
DE69721838T 1996-09-25 1997-09-15 1-[1-(4-chlorphenyl)cyclobutyl]-3-methylbutyl amin derivate zur senkung von harnsäurespiegeln beim menschen Expired - Fee Related DE69721838T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9619962 1996-09-25
GBGB9619962.5A GB9619962D0 (en) 1996-09-25 1996-09-25 Medical treatment
PCT/EP1997/005034 WO1998013033A1 (en) 1996-09-25 1997-09-15 Medical treatment

Publications (2)

Publication Number Publication Date
DE69721838D1 true DE69721838D1 (de) 2003-06-12
DE69721838T2 DE69721838T2 (de) 2004-01-22

Family

ID=10800448

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69721838T Expired - Fee Related DE69721838T2 (de) 1996-09-25 1997-09-15 1-[1-(4-chlorphenyl)cyclobutyl]-3-methylbutyl amin derivate zur senkung von harnsäurespiegeln beim menschen

Country Status (26)

Country Link
US (1) US6162831A (de)
EP (1) EP1007023B1 (de)
JP (1) JP2001501608A (de)
KR (1) KR20000048568A (de)
CN (1) CN1231604A (de)
AT (1) ATE239460T1 (de)
AU (1) AU722129B2 (de)
BG (1) BG103278A (de)
BR (1) BR9711414A (de)
CA (1) CA2266438A1 (de)
DE (1) DE69721838T2 (de)
DK (1) DK1007023T3 (de)
ES (1) ES2199374T3 (de)
GB (1) GB9619962D0 (de)
HR (1) HRP970519A2 (de)
HU (1) HUP9904545A3 (de)
IL (1) IL128851A (de)
NO (1) NO991425D0 (de)
NZ (1) NZ334668A (de)
PL (1) PL332423A1 (de)
PT (1) PT1007023E (de)
SK (1) SK32199A3 (de)
TR (1) TR199900649T2 (de)
TW (1) TW415842B (de)
WO (1) WO1998013033A1 (de)
ZA (1) ZA978573B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6331571B1 (en) 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
PL365463A1 (en) * 1999-03-19 2005-01-10 Knoll Gmbh Treatment of osteoarthritis
US6552087B1 (en) 1999-03-19 2003-04-22 Abbott Gmbh & Co. Kg Therapeutic agent comprising (+)-sibutramine
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
WO2002083631A1 (en) 2001-04-13 2002-10-24 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
US9655932B2 (en) * 2002-03-13 2017-05-23 Kibow Biotech, Inc. Composition and method for preventing or treating gout or hyperuricemia
US11103542B2 (en) 2002-03-13 2021-08-31 Kibow Biotech, Inc. Composition and method for maintaining healthy kidney function
JP4278652B2 (ja) * 2002-10-05 2009-06-17 ハンミ ファーム． シーオー．， エルティーディー． 結晶性シブトラミンメタンスルホン酸塩半水和物を含む医薬組成物
US20050131074A1 (en) * 2003-08-04 2005-06-16 Beckman Kristen M. Methods for treating metabolic syndrome
WO2006012438A2 (en) * 2004-07-21 2006-02-02 University Of Florida Research Foundation, Inc. Compositions and methods for treatment and prevention of insulin resistance
KR100627687B1 (ko) * 2005-04-20 2006-09-25 주식회사 씨티씨바이오 시부트라민 유리염기 함유 조성물 및 이의 제조방법
KR20080046601A (ko) * 2006-11-22 2008-05-27 에스케이케미칼주식회사 보관안정성이 우수한 시부트라민 함유 포접복합체
US11179426B2 (en) 2016-12-29 2021-11-23 Kibow Biotech, Inc. Composition and method for maintaining healthy kidney function
EP3906059A4 (de) * 2018-11-02 2022-06-22 Ampersand Biopharmaceuticals, Inc. Verwaltung des risikos auf kationenüberladung und elektrolytungleichgewicht mit topisch angewendeten puffern

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
GB8531071D0 (en) * 1985-12-17 1986-01-29 Boots Co Plc Therapeutic compound
GB8704777D0 (en) * 1987-02-28 1987-04-01 Boots Co Plc Medical treatment
JP2675573B2 (ja) * 1988-03-31 1997-11-12 科研製薬株式会社 脳機能改善剤
IE61928B1 (en) * 1988-11-29 1994-11-30 Boots Co Plc Treatment of obesity
EP0647134A4 (de) * 1992-06-23 1997-07-30 Sepracor Inc Verfahren und zusammensetzungen zur behandlung von depression und anderen erkrankungen unter verwendung von optisch-reinem sibutramin.
EP0708639A4 (de) * 1992-06-23 1997-08-20 Sepracor Inc Verfahern und zusammensetzungen zur behandlumng von depression und anderen erkrankungen unter verwendung von optisch-reienem sibuttramin
US5459164A (en) * 1994-02-03 1995-10-17 Boots Pharmaceuticals, Inc. Medical treatment

Also Published As

Publication number Publication date
PL332423A1 (en) 1999-09-13
KR20000048568A (ko) 2000-07-25
AU722129B2 (en) 2000-07-20
ZA978573B (en) 1999-03-25
NZ334668A (en) 2000-07-28
HUP9904545A2 (hu) 2000-11-28
HRP970519A2 (en) 1998-08-31
SK32199A3 (en) 1999-12-10
IL128851A (en) 2001-08-26
GB9619962D0 (en) 1996-11-13
NO991425L (no) 1999-03-24
BG103278A (en) 2000-01-31
NO991425D0 (no) 1999-03-24
ES2199374T3 (es) 2004-02-16
DE69721838T2 (de) 2004-01-22
HUP9904545A3 (en) 2000-12-28
EP1007023B1 (de) 2003-05-07
BR9711414A (pt) 2000-04-25
EP1007023A1 (de) 2000-06-14
TR199900649T2 (xx) 1999-07-21
US6162831A (en) 2000-12-19
IL128851A0 (en) 2000-01-31
CN1231604A (zh) 1999-10-13
WO1998013033A1 (en) 1998-04-02
AU4385197A (en) 1998-04-17
DK1007023T3 (da) 2003-08-25
TW415842B (en) 2000-12-21
JP2001501608A (ja) 2001-02-06
CA2266438A1 (en) 1998-04-02
PT1007023E (pt) 2003-08-29
ATE239460T1 (de) 2003-05-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee