HUP0101012A2 - Orálisan adagolható gyógyszerkompozíció - Google Patents
Orálisan adagolható gyógyszerkompozícióInfo
- Publication number
- HUP0101012A2 HUP0101012A2 HU0101012A HUP0101012A HUP0101012A2 HU P0101012 A2 HUP0101012 A2 HU P0101012A2 HU 0101012 A HU0101012 A HU 0101012A HU P0101012 A HUP0101012 A HU P0101012A HU P0101012 A2 HUP0101012 A2 HU P0101012A2
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical composition
- oral administration
- effect
- tetrahydropyridine
- trifluoromethylfend
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 2
- 125000003163 2-(2-naphthyl)ethyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- VSWICNJIUPRZIK-UHFFFAOYSA-N 2-piperideine Chemical class C1CNC=CC1 VSWICNJIUPRZIK-UHFFFAOYSA-N 0.000 abstract 1
- 206010010774 Constipation Diseases 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 210000000944 nerve tissue Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
Találmányunk tárgya iható vizes oldat, amely 1-[2-(2-naftil)-etil]-4-(3-trifluormetil-fend)-1,2,3,6-tetrahidropiridin-hidrokloridot <-ciklodextrint (<-CD), és valamely gyógyászatilag elfogadott savat vagypuffert tartalmaz, amely 3 vagy ennél alacsonyabb pH-t biztosít. Afenti tetrahidropiridinszármazéknak ismert az antidepresszív hatása,az idegszövetet tápláló hatása, székrekedés ellenes hatása. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9716529A FR2772614B1 (fr) | 1997-12-24 | 1997-12-24 | Solution aqueuse a base de chlorhydrate de 1- [ 2-(2-naphtyl)ethyl]-4- (3-trifluoromethylphenyl) -1,2,3,6-tetrahydropyridine et composition pharmaceutique buvable en contenant |
PCT/FR1998/002712 WO1999033466A1 (fr) | 1997-12-24 | 1998-12-14 | Composition pharmaceutique buvable |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0101012A2 true HUP0101012A2 (hu) | 2001-08-28 |
HUP0101012A3 HUP0101012A3 (en) | 2002-12-28 |
Family
ID=9515152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0101012A HUP0101012A3 (en) | 1997-12-24 | 1998-12-14 | Pharmaceutical composition for oral administration |
Country Status (25)
Country | Link |
---|---|
US (1) | US6191137B1 (hu) |
EP (1) | EP1041984B1 (hu) |
JP (1) | JP2002510599A (hu) |
AR (1) | AR017722A1 (hu) |
AT (1) | ATE252384T1 (hu) |
AU (1) | AU1880599A (hu) |
BR (1) | BR9814414A (hu) |
CA (1) | CA2315696C (hu) |
CO (1) | CO4970813A1 (hu) |
DE (1) | DE69819203T2 (hu) |
DK (1) | DK1041984T3 (hu) |
DZ (1) | DZ2676A1 (hu) |
ES (1) | ES2209238T3 (hu) |
FR (1) | FR2772614B1 (hu) |
GT (1) | GT199800204A (hu) |
HU (1) | HUP0101012A3 (hu) |
MY (1) | MY117156A (hu) |
NO (1) | NO20003284L (hu) |
PT (1) | PT1041984E (hu) |
SA (2) | SA99191002B1 (hu) |
SI (1) | SI1041984T1 (hu) |
TW (1) | TW536409B (hu) |
UY (1) | UY25320A1 (hu) |
WO (1) | WO1999033466A1 (hu) |
ZA (1) | ZA9811824B (hu) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004087870A2 (en) * | 2003-03-25 | 2004-10-14 | The Johns Hopkins University | Neuronal cell lineages and methods of production thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2702656B1 (fr) * | 1993-03-18 | 1995-06-16 | Sanofi Elf | Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments cardioprotecteurs. |
-
1997
- 1997-12-24 FR FR9716529A patent/FR2772614B1/fr not_active Expired - Fee Related
-
1998
- 1998-12-14 EP EP98963579A patent/EP1041984B1/fr not_active Expired - Lifetime
- 1998-12-14 PT PT98963579T patent/PT1041984E/pt unknown
- 1998-12-14 BR BR9814414-6A patent/BR9814414A/pt not_active Application Discontinuation
- 1998-12-14 JP JP2000526223A patent/JP2002510599A/ja active Pending
- 1998-12-14 AT AT98963579T patent/ATE252384T1/de not_active IP Right Cessation
- 1998-12-14 ES ES98963579T patent/ES2209238T3/es not_active Expired - Lifetime
- 1998-12-14 DK DK98963579T patent/DK1041984T3/da active
- 1998-12-14 SI SI9830580T patent/SI1041984T1/xx unknown
- 1998-12-14 AU AU18805/99A patent/AU1880599A/en not_active Abandoned
- 1998-12-14 US US09/581,718 patent/US6191137B1/en not_active Expired - Fee Related
- 1998-12-14 WO PCT/FR1998/002712 patent/WO1999033466A1/fr active IP Right Grant
- 1998-12-14 CA CA002315696A patent/CA2315696C/en not_active Expired - Fee Related
- 1998-12-14 DE DE69819203T patent/DE69819203T2/de not_active Expired - Fee Related
- 1998-12-14 HU HU0101012A patent/HUP0101012A3/hu unknown
- 1998-12-15 DZ DZ980286A patent/DZ2676A1/xx active
- 1998-12-17 CO CO98075012A patent/CO4970813A1/es unknown
- 1998-12-21 UY UY25320A patent/UY25320A1/es not_active IP Right Cessation
- 1998-12-22 GT GT199800204A patent/GT199800204A/es unknown
- 1998-12-22 AR ARP980106588A patent/AR017722A1/es active IP Right Grant
- 1998-12-23 TW TW087121529A patent/TW536409B/zh not_active IP Right Cessation
- 1998-12-23 ZA ZA9811824A patent/ZA9811824B/xx unknown
- 1998-12-24 MY MYPI98005880A patent/MY117156A/en unknown
-
1999
- 1999-01-26 SA SA99191002A patent/SA99191002B1/ar unknown
- 1999-01-26 SA SA99191003A patent/SA99191003B1/ar unknown
-
2000
- 2000-06-22 NO NO20003284A patent/NO20003284L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2315696C (en) | 2008-01-29 |
FR2772614A1 (fr) | 1999-06-25 |
GT199800204A (es) | 2000-06-14 |
AU1880599A (en) | 1999-07-19 |
HUP0101012A3 (en) | 2002-12-28 |
FR2772614B1 (fr) | 2000-03-10 |
US6191137B1 (en) | 2001-02-20 |
PT1041984E (pt) | 2004-02-27 |
DE69819203T2 (de) | 2004-07-15 |
EP1041984B1 (fr) | 2003-10-22 |
CA2315696A1 (en) | 1999-07-08 |
WO1999033466A1 (fr) | 1999-07-08 |
NO20003284D0 (no) | 2000-06-22 |
SA99191002B1 (ar) | 2006-03-07 |
JP2002510599A (ja) | 2002-04-09 |
ZA9811824B (en) | 1999-06-29 |
TW536409B (en) | 2003-06-11 |
MY117156A (en) | 2004-05-31 |
DZ2676A1 (fr) | 2004-09-19 |
SI1041984T1 (en) | 2004-04-30 |
EP1041984A1 (fr) | 2000-10-11 |
SA99191003B1 (ar) | 2006-10-02 |
BR9814414A (pt) | 2000-10-10 |
NO20003284L (no) | 2000-08-24 |
DE69819203D1 (de) | 2003-11-27 |
AR017722A1 (es) | 2001-09-12 |
ES2209238T3 (es) | 2004-06-16 |
DK1041984T3 (da) | 2004-02-16 |
UY25320A1 (es) | 2000-10-31 |
ATE252384T1 (de) | 2003-11-15 |
CO4970813A1 (es) | 2000-11-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |