DE69721250D1 - Zusammensetzungen zur kontrasterhöhung in der kernspin-tomographie für untersuchungen des verdauungstraktes von patienten - Google Patents

Zusammensetzungen zur kontrasterhöhung in der kernspin-tomographie für untersuchungen des verdauungstraktes von patienten

Info

Publication number
DE69721250D1
DE69721250D1 DE69721250T DE69721250T DE69721250D1 DE 69721250 D1 DE69721250 D1 DE 69721250D1 DE 69721250 T DE69721250 T DE 69721250T DE 69721250 T DE69721250 T DE 69721250T DE 69721250 D1 DE69721250 D1 DE 69721250D1
Authority
DE
Germany
Prior art keywords
examinations
patients
compositions
nuclear spin
paramagnetic metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69721250T
Other languages
English (en)
Other versions
DE69721250T2 (de
Inventor
Herve Tournier
Philippe Bussat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Research SA
Original Assignee
Bracco Research SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Research SA filed Critical Bracco Research SA
Application granted granted Critical
Publication of DE69721250D1 publication Critical patent/DE69721250D1/de
Publication of DE69721250T2 publication Critical patent/DE69721250T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F22/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides or nitriles thereof
    • C08F22/10—Esters
    • C08F22/1006—Esters of polyhydric alcohols or polyhydric phenols, e.g. ethylene glycol dimethacrylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/10—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10—Esters
    • C08F20/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • C08F20/36—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate containing oxygen in addition to the carboxy oxygen, e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE69721250T 1996-12-23 1997-12-23 Zusammensetzungen zur kontrasterhöhung in der kernspin-tomographie für untersuchungen des verdauungstraktes von patienten Expired - Lifetime DE69721250T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96810888 1996-12-23
EP96810888 1996-12-23
PCT/IB1997/001594 WO1998028258A1 (en) 1996-12-23 1997-12-23 Compositions for increasing the mri contrast in visualising the digestive tract of patients

Publications (2)

Publication Number Publication Date
DE69721250D1 true DE69721250D1 (de) 2003-05-28
DE69721250T2 DE69721250T2 (de) 2004-02-19

Family

ID=8225777

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69721250T Expired - Lifetime DE69721250T2 (de) 1996-12-23 1997-12-23 Zusammensetzungen zur kontrasterhöhung in der kernspin-tomographie für untersuchungen des verdauungstraktes von patienten

Country Status (6)

Country Link
US (2) US6060040A (de)
EP (1) EP0904264B1 (de)
JP (1) JP4432000B2 (de)
AT (1) ATE238272T1 (de)
DE (1) DE69721250T2 (de)
WO (1) WO1998028258A1 (de)

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US6723052B2 (en) * 2001-06-07 2004-04-20 Stanley L. Mills Echogenic medical device
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US20040265235A1 (en) * 2003-06-26 2004-12-30 Uzgiris Egidijus Edward Magnetic resonance contrast-enhancing agents and method for detecting and imaging artherosclerotic plaque
US20050152842A1 (en) * 2003-12-24 2005-07-14 Chun Li Poly (L-glutamic acid) paramagnetic material complex and use as a biodegradable MRI contrast agent
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DE102004038134B4 (de) * 2004-08-05 2013-07-25 Johann Wolfgang Goethe-Universität Frankfurt am Main Multivalente Chelatoren zum Modifizieren und Organisieren von Zielmolekülen, Verfahren zu ihrer Herstellung sowie ihre Verwendung
EP1647283A1 (de) * 2004-10-12 2006-04-19 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Polymerisches Kontrastmittel
CN101203249A (zh) * 2005-04-01 2008-06-18 德克萨斯大学体系董事会 多（肽）作为螯合剂：制造方法和用途
US8457712B2 (en) 2005-12-30 2013-06-04 Wisconsin Alumni Research Foundation Multi-mode medical device system and methods of manufacturing and using same
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WO2008035759A1 (fr) * 2006-09-22 2008-03-27 Terumo Kabushiki Kaisha Polymère visible en imagerie par résonance magnétique et permettant d'obtenir une surface lubrifiée et dispositif médical
US7875747B2 (en) * 2006-10-10 2011-01-25 Afton Chemical Corporation Branched succinimide dispersant compounds and methods of making the compounds
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Also Published As

Publication number Publication date
US6241968B1 (en) 2001-06-05
WO1998028258A1 (en) 1998-07-02
EP0904264B1 (de) 2003-04-23
ATE238272T1 (de) 2003-05-15
DE69721250T2 (de) 2004-02-19
US6060040A (en) 2000-05-09
JP4432000B2 (ja) 2010-03-17
EP0904264A1 (de) 1999-03-31
JP2000507962A (ja) 2000-06-27

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