ATE167665T1 - Hydroxamat- und hydrazidderivate von polyaminen und ihre medizinische verwendung als chelatierende wirkstoffe - Google Patents
Hydroxamat- und hydrazidderivate von polyaminen und ihre medizinische verwendung als chelatierende wirkstoffeInfo
- Publication number
- ATE167665T1 ATE167665T1 AT92915605T AT92915605T ATE167665T1 AT E167665 T1 ATE167665 T1 AT E167665T1 AT 92915605 T AT92915605 T AT 92915605T AT 92915605 T AT92915605 T AT 92915605T AT E167665 T1 ATE167665 T1 AT E167665T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- agents
- hydroxamat
- polyamines
- chelating agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C243/34—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a carbon skeleton further substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Materials For Medical Uses (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919115375A GB9115375D0 (en) | 1991-07-17 | 1991-07-17 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE167665T1 true ATE167665T1 (de) | 1998-07-15 |
Family
ID=10698465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92915605T ATE167665T1 (de) | 1991-07-17 | 1992-07-16 | Hydroxamat- und hydrazidderivate von polyaminen und ihre medizinische verwendung als chelatierende wirkstoffe |
Country Status (9)
Country | Link |
---|---|
US (1) | US5869651A (de) |
EP (1) | EP0594734B1 (de) |
JP (1) | JPH07500574A (de) |
AT (1) | ATE167665T1 (de) |
AU (1) | AU2320392A (de) |
DE (1) | DE69226022T2 (de) |
ES (1) | ES2117670T3 (de) |
GB (1) | GB9115375D0 (de) |
WO (1) | WO1993002045A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0660925A1 (de) * | 1990-11-21 | 1995-07-05 | Mallinckrodt Medical, Inc. | Chelate von alkoxyamidderivaten für die bilderzeugung mit magnetischer resonanz |
GB2267494B (en) * | 1992-06-02 | 1995-09-20 | Ciba Geigy Ag | Trisamidodithionodiphosphates |
WO1994019311A1 (en) * | 1993-02-23 | 1994-09-01 | Merrell Dow Pharmaceuticals Inc. | Polyamine derivatives as radioprotective agents |
DE4340809C2 (de) * | 1993-11-24 | 2000-08-03 | Schering Ag | 1.4,7,10-Tetraazacyclododecan-Derivate, diese enthaltende pharmazeutische Mittel und Verfahren zu deren Herstellung |
DK0686143T3 (da) * | 1993-12-27 | 1999-05-17 | Novartis Ag | Umættede aminoforbindelser som middel mod cancer og mod protozoer |
JPH08508048A (ja) * | 1994-01-12 | 1996-08-27 | ブラッコ インターナショナル ベスローテン フェンノートシャップ | リガンド及びその金属錯体 |
ES2096517B1 (es) * | 1994-02-21 | 1998-02-01 | Diaz Agustin Espina | Equipo para el control de suministro de servicios a viviendas, locales y similares. |
US5476644A (en) * | 1994-04-13 | 1995-12-19 | Sterling Winthrop Inc. | Cyclic triamine chelating agents |
US6693190B1 (en) | 1994-05-11 | 2004-02-17 | Bracco International B.V. | Enhanced relaxivity monomeric and multimeric compounds |
KR100832956B1 (ko) * | 2000-04-24 | 2008-05-27 | 로무 가부시키가이샤 | 측면발광반도체 발광장치 |
NO20051911D0 (no) * | 2005-04-19 | 2005-04-19 | Amersham Health As | Synthesis |
CA2631784A1 (en) * | 2005-11-29 | 2007-06-07 | Mallinckrodt Inc. | Bifunctional metal chelating conjugates |
CN101970015B (zh) | 2008-01-08 | 2014-05-07 | 兰休斯医疗成像公司 | 作为显像剂的n-烷氧基酰胺共轭物 |
US8877157B2 (en) | 2009-07-08 | 2014-11-04 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
MX2022007108A (es) | 2019-12-13 | 2022-07-11 | Bracco Imaging Spa | Fabricacion de do3a protegido. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL6711460A (de) * | 1967-08-18 | 1969-02-20 | ||
US4609757A (en) * | 1983-08-10 | 1986-09-02 | Nuclear Technology Corporation | Hydrazides of amino-polyacetic acids as chelants |
DE3855239T2 (de) * | 1987-07-16 | 1996-10-31 | Nycomed Imaging As | Aminocarbonsäure und Derivate |
GB8900732D0 (en) * | 1989-01-13 | 1989-03-08 | Nycomed As | Agents |
US5384108A (en) * | 1989-04-24 | 1995-01-24 | Mallinckrodt Medical, Inc. | Magnetic resonance imaging agents |
HU219336B (en) * | 1989-07-20 | 2001-03-28 | Novartis Ag | Process for producing peptide derivatives and pharmaceutical compositions comprising such compounds and diagnostic unit containing such compounds |
WO1991010669A1 (en) * | 1990-01-19 | 1991-07-25 | Cockbain, Julian, Roderick, Michaelson | Chelating compounds |
-
1991
- 1991-07-17 GB GB919115375A patent/GB9115375D0/en active Pending
-
1992
- 1992-07-16 US US08/190,143 patent/US5869651A/en not_active Expired - Fee Related
- 1992-07-16 AU AU23203/92A patent/AU2320392A/en not_active Abandoned
- 1992-07-16 AT AT92915605T patent/ATE167665T1/de not_active IP Right Cessation
- 1992-07-16 WO PCT/EP1992/001598 patent/WO1993002045A1/en active IP Right Grant
- 1992-07-16 JP JP5502577A patent/JPH07500574A/ja active Pending
- 1992-07-16 ES ES92915605T patent/ES2117670T3/es not_active Expired - Lifetime
- 1992-07-16 EP EP92915605A patent/EP0594734B1/de not_active Expired - Lifetime
- 1992-07-16 DE DE69226022T patent/DE69226022T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2320392A (en) | 1993-02-23 |
EP0594734A1 (de) | 1994-05-04 |
DE69226022D1 (de) | 1998-07-30 |
ES2117670T3 (es) | 1998-08-16 |
EP0594734B1 (de) | 1998-06-24 |
JPH07500574A (ja) | 1995-01-19 |
GB9115375D0 (en) | 1991-09-04 |
WO1993002045A1 (en) | 1993-02-04 |
DE69226022T2 (de) | 1999-04-01 |
US5869651A (en) | 1999-02-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE167665T1 (de) | Hydroxamat- und hydrazidderivate von polyaminen und ihre medizinische verwendung als chelatierende wirkstoffe | |
ES2088492T3 (es) | Uso de particulas superparamagneticas para analisis magnetometricos (squid). | |
GB9200387D0 (en) | Improvements in or relating to contrast agents | |
ATE138809T1 (de) | Anwendung von chelat-komplexen | |
ES2085617T3 (es) | Ion paramagnetico incluido en tamiz molecular para diagnostico. | |
ATE252916T1 (de) | Verabreichbare formulierugen und ihre anwendung in mri | |
ATE454390T1 (de) | Amphipatische polycarboxylchelaten und komplexen mit paramagnetischen metallen als mri kontrastmitteln | |
DE69320173T2 (de) | Kontrastmittel | |
NO933421L (no) | Konstrastmiddel | |
DE3854717D1 (de) | Verfahren zur erhöhung der sicherheit von metall-ligandchelaten als röntgenstrahlen-kontrastmittel. | |
DE69120826T2 (de) | Chelatbildende mittel | |
BR9508435A (pt) | Quelentes macrocíclicos seus quelatos e usos dos mesmos no campo diagnóstico |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |