ATE167665T1 - Hydroxamat- und hydrazidderivate von polyaminen und ihre medizinische verwendung als chelatierende wirkstoffe - Google Patents
Hydroxamat- und hydrazidderivate von polyaminen und ihre medizinische verwendung als chelatierende wirkstoffeInfo
- Publication number
- ATE167665T1 ATE167665T1 AT92915605T AT92915605T ATE167665T1 AT E167665 T1 ATE167665 T1 AT E167665T1 AT 92915605 T AT92915605 T AT 92915605T AT 92915605 T AT92915605 T AT 92915605T AT E167665 T1 ATE167665 T1 AT E167665T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- agents
- hydroxamat
- polyamines
- chelating agents
- Prior art date
Links
- 239000002738 chelating agent Substances 0.000 title 1
- 229920000768 polyamine Polymers 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 239000002872 contrast media Substances 0.000 abstract 1
- 238000001784 detoxification Methods 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 238000002059 diagnostic imaging Methods 0.000 abstract 1
- 239000002405 nuclear magnetic resonance imaging agent Substances 0.000 abstract 1
- 230000005298 paramagnetic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C243/34—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a carbon skeleton further substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919115375A GB9115375D0 (en) | 1991-07-17 | 1991-07-17 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE167665T1 true ATE167665T1 (de) | 1998-07-15 |
Family
ID=10698465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92915605T ATE167665T1 (de) | 1991-07-17 | 1992-07-16 | Hydroxamat- und hydrazidderivate von polyaminen und ihre medizinische verwendung als chelatierende wirkstoffe |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5869651A (de) |
| EP (1) | EP0594734B1 (de) |
| JP (1) | JPH07500574A (de) |
| AT (1) | ATE167665T1 (de) |
| AU (1) | AU2320392A (de) |
| DE (1) | DE69226022T2 (de) |
| ES (1) | ES2117670T3 (de) |
| GB (1) | GB9115375D0 (de) |
| WO (1) | WO1993002045A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0660925A1 (de) * | 1990-11-21 | 1995-07-05 | Mallinckrodt Medical, Inc. | Chelate von alkoxyamidderivaten für die bilderzeugung mit magnetischer resonanz |
| GB2267494B (en) * | 1992-06-02 | 1995-09-20 | Ciba Geigy Ag | Trisamidodithionodiphosphates |
| EP0686142B1 (de) * | 1993-02-23 | 1998-12-30 | Merrell Pharmaceuticals Inc. | Polyaminderivate als strahlenschutzmittel |
| DE4340809C2 (de) * | 1993-11-24 | 2000-08-03 | Schering Ag | 1.4,7,10-Tetraazacyclododecan-Derivate, diese enthaltende pharmazeutische Mittel und Verfahren zu deren Herstellung |
| NZ277503A (en) * | 1993-12-27 | 1997-07-27 | Ciba Geigy Ag | 1,5,10,14-tetraazatetradec-7-ene derivatives; pharmaceutical compositions thereof |
| CA2156605A1 (en) * | 1994-01-12 | 1995-07-20 | Bracco International B.V. | Ligands and metal complexes thereof |
| ES2096517B1 (es) * | 1994-02-21 | 1998-02-01 | Diaz Agustin Espina | Equipo para el control de suministro de servicios a viviendas, locales y similares. |
| US5476644A (en) * | 1994-04-13 | 1995-12-19 | Sterling Winthrop Inc. | Cyclic triamine chelating agents |
| US6693190B1 (en) | 1994-05-11 | 2004-02-17 | Bracco International B.V. | Enhanced relaxivity monomeric and multimeric compounds |
| EP1204151A4 (de) * | 2000-04-24 | 2006-10-18 | Rohm Co Ltd | Seitlich emittierende leuchtdiode und herstellungsmethode |
| NO20051911D0 (no) | 2005-04-19 | 2005-04-19 | Amersham Health As | Synthesis |
| US20080279768A1 (en) * | 2005-11-29 | 2008-11-13 | Moore Dennis A | Bifunctional Metal Chelating Conjugates |
| JP5730581B2 (ja) * | 2008-01-08 | 2015-06-10 | ランセウス メディカル イメージング， インコーポレイテッド | 造影剤としてのｎ−アルコキシアミド抱合体 |
| EP2451776B1 (de) | 2009-07-08 | 2019-09-18 | Lantheus Medical Imaging, Inc. | N-alkoxyamidkonjugate als bildgebungsmittel |
| BR112022009493A2 (pt) | 2019-12-13 | 2022-08-16 | Bracco Imaging Spa | Fabricação de do3a protegido |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1197798A (en) * | 1967-08-18 | 1970-07-08 | Frederick Charles Bersworth | Chelating Compounds Derived from Amino Acid Derivatives |
| US4609757A (en) * | 1983-08-10 | 1986-09-02 | Nuclear Technology Corporation | Hydrazides of amino-polyacetic acids as chelants |
| DE3855239T2 (de) * | 1987-07-16 | 1996-10-31 | Nycomed Imaging As | Aminocarbonsäure und Derivate |
| GB8900732D0 (en) * | 1989-01-13 | 1989-03-08 | Nycomed As | Agents |
| US5384108A (en) * | 1989-04-24 | 1995-01-24 | Mallinckrodt Medical, Inc. | Magnetic resonance imaging agents |
| DE69018226T2 (de) * | 1989-07-20 | 1995-09-21 | Sandoz-Patent-Gmbh, 79539 Loerrach | Markierte polypeptidderivate. |
| EP0511275A1 (de) * | 1990-01-19 | 1992-11-04 | Nycomed Imaging As | Komplexbildner |
| GB9008134D0 (en) | 1990-04-10 | 1990-06-06 | Murrell Stewart R | Automatic door knocker |
-
1991
- 1991-07-17 GB GB919115375A patent/GB9115375D0/en active Pending
-
1992
- 1992-07-16 EP EP92915605A patent/EP0594734B1/de not_active Expired - Lifetime
- 1992-07-16 AU AU23203/92A patent/AU2320392A/en not_active Abandoned
- 1992-07-16 JP JP5502577A patent/JPH07500574A/ja active Pending
- 1992-07-16 DE DE69226022T patent/DE69226022T2/de not_active Expired - Fee Related
- 1992-07-16 AT AT92915605T patent/ATE167665T1/de not_active IP Right Cessation
- 1992-07-16 ES ES92915605T patent/ES2117670T3/es not_active Expired - Lifetime
- 1992-07-16 WO PCT/EP1992/001598 patent/WO1993002045A1/en not_active Ceased
- 1992-07-16 US US08/190,143 patent/US5869651A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2320392A (en) | 1993-02-23 |
| ES2117670T3 (es) | 1998-08-16 |
| DE69226022D1 (de) | 1998-07-30 |
| US5869651A (en) | 1999-02-09 |
| EP0594734B1 (de) | 1998-06-24 |
| GB9115375D0 (en) | 1991-09-04 |
| EP0594734A1 (de) | 1994-05-04 |
| JPH07500574A (ja) | 1995-01-19 |
| WO1993002045A1 (en) | 1993-02-04 |
| DE69226022T2 (de) | 1999-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |