DE69720026T2 - Verfahren zur herstellung von d-aminosäuren durch direkte gärung - Google Patents

Verfahren zur herstellung von d-aminosäuren durch direkte gärung Download PDF

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Publication number
DE69720026T2
DE69720026T2 DE69720026T DE69720026T DE69720026T2 DE 69720026 T2 DE69720026 T2 DE 69720026T2 DE 69720026 T DE69720026 T DE 69720026T DE 69720026 T DE69720026 T DE 69720026T DE 69720026 T2 DE69720026 T2 DE 69720026T2
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DE
Germany
Prior art keywords
cell
amino acids
relates
producing
culture medium
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69720026T
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English (en)
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DE69720026D1 (de
Inventor
G Fotheringham
P Taylor
L Ton
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PCBU Services Inc
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PCBU Services Inc
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Application filed by PCBU Services Inc filed Critical PCBU Services Inc
Publication of DE69720026D1 publication Critical patent/DE69720026D1/de
Application granted granted Critical
Publication of DE69720026T2 publication Critical patent/DE69720026T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69720026T 1996-09-30 1997-09-25 Verfahren zur herstellung von d-aminosäuren durch direkte gärung Expired - Lifetime DE69720026T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/723,896 US5728555A (en) 1996-09-30 1996-09-30 Preparation of d-amino acids by direct fermentative means
PCT/US1997/017133 WO1998014602A2 (en) 1996-09-30 1997-09-25 Preparation of d-amino acids by direct fermentative means

Publications (2)

Publication Number Publication Date
DE69720026D1 DE69720026D1 (de) 2003-04-24
DE69720026T2 true DE69720026T2 (de) 2004-01-15

Family

ID=24908159

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69720026T Expired - Lifetime DE69720026T2 (de) 1996-09-30 1997-09-25 Verfahren zur herstellung von d-aminosäuren durch direkte gärung

Country Status (9)

Country Link
US (1) US5728555A (de)
EP (1) EP0937156B1 (de)
JP (1) JP4548864B2 (de)
KR (1) KR20000048776A (de)
AT (1) ATE234933T1 (de)
AU (1) AU728884B2 (de)
CA (1) CA2267205A1 (de)
DE (1) DE69720026T2 (de)
WO (1) WO1998014602A2 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358714B1 (en) * 1995-04-03 2002-03-19 The Nutrasweet Company Materials and methods for the production of D-phenylalanine
JPH10286098A (ja) * 1997-02-14 1998-10-27 Daicel Chem Ind Ltd Ｄ−アミノ酸の製造方法、ならびにアミンの製造方法
WO2000023609A1 (en) * 1998-10-19 2000-04-27 Nsc Technologies Llc Transaminase biotransformation process employing glutamic acid
US6365380B2 (en) * 2000-02-23 2002-04-02 Pcbu Services, Inc. Method for stereoselectively inverting a chiral center of a chemical compound using an enzyme and a metal catalyst
AU2001285833A1 (en) * 2000-07-24 2002-02-05 Degussa A.G. Process for the fermentative preparation of l-glutamic acid using coryneform bacteria
US8048665B2 (en) * 2000-07-24 2011-11-01 Evonik Degussa Gmbh Nucleotide sequences encoding alanine racemase from coryneform
DE10046934A1 (de) * 2000-09-21 2002-04-18 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren
US7186532B2 (en) 2000-11-01 2007-03-06 Kyowa Hakko Kogyo Co., Ltd. Process for producing D-serine
US7297800B2 (en) * 2001-12-27 2007-11-20 Ajinomoto Co., Inc. Process of producing glutamate derivatives
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US8372989B2 (en) * 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
EP2280068A1 (de) 2002-08-26 2011-02-02 Ajinomoto Co., Inc. Neuartige Aldolase und Herstellungsverfahren für substituierte Alpha-Ketosäuren
DE10251184A1 (de) * 2002-11-04 2004-05-13 Degussa Ag Mutanten zur Herstellung von D-Aminosäuren
KR100723826B1 (ko) 2002-12-09 2007-06-04 아지노모토 가부시키가이샤 변이형 ｄ－아미노트랜스퍼라제 및 이를 사용하는 광학활성글루탐산 유도체의 제조방법
US20050112260A1 (en) * 2003-08-01 2005-05-26 Cargill, Inc. Monatin tabletop sweetener compositions and methods of making same
JP2007503214A (ja) * 2003-08-25 2007-02-22 カーギル，インコーポレイティド モナチンを含む飲料組成物及びその製造方法
KR101158592B1 (ko) * 2003-10-21 2012-06-22 카아길, 인코포레이팃드 모나틴 및 모나틴 전구체의 생산
US7180370B2 (en) * 2004-09-01 2007-02-20 Micron Technology, Inc. CMOS amplifiers with frequency compensating capacitors
US8158389B2 (en) * 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US8153405B2 (en) * 2005-04-20 2012-04-10 Cargill, Incorporated Products and methods for in vivo secretion of monatin
EP1883697A4 (de) 2005-04-26 2010-05-05 Cargill Inc Polypeptide und biosynthesewege zur herstellung von stereoisomeren von monatin und deren vorläufern
EP1994161A2 (de) 2006-03-07 2008-11-26 Cargill, Incorporated Aldolasen, diese kodierende nukleinsäuren und verfahren zu deren herstellung und verwendung
AU2007267618B2 (en) * 2006-05-24 2013-07-18 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
US20090198072A1 (en) * 2006-05-24 2009-08-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
WO2008080138A1 (en) 2006-12-22 2008-07-03 Richmond Chemical Corporation Stereoinversion of amino acids
EP2132322A4 (de) * 2007-03-02 2013-02-20 Richmond Chemical Corp Verfahren zur erhöhung der ausbeute und verbesserung der reinigung von produkten aus transaminasereaktionen
KR20120098235A (ko) * 2011-02-28 2012-09-05 이화여자대학교 산학협력단 비천연 아미노산 생산 균주 및 이를 이용한 비천연 아미노산의 제조 방법
CN104744278A (zh) * 2015-03-09 2015-07-01 黄冈威尔曼生物科技有限责任公司 一种新型l-缬氨酸的制备工艺
CN108384818A (zh) * 2018-05-18 2018-08-10 南京大学 一种酶法转化制备d-组氨酸的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0785718B2 (ja) * 1986-03-07 1995-09-20 ダイセル化学工業株式会社 Ｄ−アミノ酸の製造方法
US4753883A (en) * 1986-05-07 1988-06-28 Biotechnica International, Inc. Enzyme deregulation
JPS63112978A (ja) * 1986-10-31 1988-05-18 Daicel Chem Ind Ltd エシエリチア・コリ
JPH01285193A (ja) * 1988-05-12 1989-11-16 Daicel Chem Ind Ltd Ｄ−アスパラギン酸の製造方法
US5120837A (en) * 1989-09-20 1992-06-09 The Nutrasweet Company Dna encoding phe a feedback inhibition resistant enzyme analogues
AU6603090A (en) * 1989-10-17 1991-05-16 Rockefeller University, The Enzymatic production of d-amino acids
US5354672A (en) * 1992-11-24 1994-10-11 Ian Fotheringham Materials and methods for hypersecretion of amino acids
JP3151075B2 (ja) * 1992-12-22 2001-04-03 協和醗酵工業株式会社 アラニンの製造法

Also Published As

Publication number Publication date
US5728555A (en) 1998-03-17
WO1998014602A3 (en) 1998-07-09
AU728884B2 (en) 2001-01-18
DE69720026D1 (de) 2003-04-24
EP0937156A2 (de) 1999-08-25
EP0937156B1 (de) 2003-03-19
KR20000048776A (ko) 2000-07-25
WO1998014602A2 (en) 1998-04-09
AU4499597A (en) 1998-04-24
JP2001505048A (ja) 2001-04-17
ATE234933T1 (de) 2003-04-15
CA2267205A1 (en) 1998-04-09
JP4548864B2 (ja) 2010-09-22

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