DE69719408T2 - Verwendung von Strontiumsälze zur Behandlung von Arthrose - Google Patents

Verwendung von Strontiumsälze zur Behandlung von Arthrose

Info

Publication number
DE69719408T2
DE69719408T2 DE69719408T DE69719408T DE69719408T2 DE 69719408 T2 DE69719408 T2 DE 69719408T2 DE 69719408 T DE69719408 T DE 69719408T DE 69719408 T DE69719408 T DE 69719408T DE 69719408 T2 DE69719408 T2 DE 69719408T2
Authority
DE
Germany
Prior art keywords
strontium salts
arthrosis
treat
treat arthrosis
strontium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69719408T
Other languages
English (en)
Other versions
DE69719408D1 (de
Inventor
Yannis Tsouderos
Pascale Deloffre
Michel Wierzbicki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Publication of DE69719408D1 publication Critical patent/DE69719408D1/de
Application granted granted Critical
Publication of DE69719408T2 publication Critical patent/DE69719408T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Medicinal Preparation (AREA)
DE69719408T 1996-06-17 1997-06-16 Verwendung von Strontiumsälze zur Behandlung von Arthrose Expired - Lifetime DE69719408T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9607475A FR2749759B1 (fr) 1996-06-17 1996-06-17 Utilisation de sels de strontium pour l'obtention de compositions pharmaceutiques destinees au traitement de l'arthrose

Publications (2)

Publication Number Publication Date
DE69719408D1 DE69719408D1 (de) 2003-04-10
DE69719408T2 true DE69719408T2 (de) 2003-12-24

Family

ID=9493102

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69719408T Expired - Lifetime DE69719408T2 (de) 1996-06-17 1997-06-16 Verwendung von Strontiumsälze zur Behandlung von Arthrose

Country Status (16)

Country Link
US (1) US5856356A (de)
EP (1) EP0813869B1 (de)
JP (1) JP3935557B2 (de)
CN (1) CN1136856C (de)
AT (1) ATE233558T1 (de)
AU (1) AU711950B2 (de)
BR (1) BR9703603A (de)
CA (1) CA2206837C (de)
DE (1) DE69719408T2 (de)
DK (1) DK0813869T3 (de)
ES (1) ES2193337T3 (de)
FR (1) FR2749759B1 (de)
HU (1) HU227935B1 (de)
NO (1) NO315840B1 (de)
NZ (1) NZ328106A (de)
ZA (1) ZA975323B (de)

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FR2828206B1 (fr) * 2001-08-03 2004-09-24 Centre Nat Rech Scient Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
NO20014746D0 (no) * 2001-09-28 2001-09-28 Clas M Kjoelberg Smertelindrende middel
FR2844797B1 (fr) * 2002-09-24 2004-10-22 Servier Lab Nouveau procede de synthese industriel des tetraesters de l'acide 5-[bis (carboxymethyl)]-3-carboxymethyl-4-cyano-2- thiophenecarboxylique, et application a la synthese des sels bivalents de l'acide ranelique et de leurs hydrates
FR2844795B1 (fr) * 2002-09-24 2004-10-22 Servier Lab Nouveau procede de synthese industriel du ranelate de strontium et de ses hydrates
FR2846558B1 (fr) * 2002-11-05 2006-07-14 Servier Lab Utilisation du sel distrontique de l'acide 2-n,n-di(carboxymethyl)amino-3-cyano-4-carboxymethyl- thiophene-5-carboxylique pour l'obtention de medicaments destines au traitement des douleurs gastro-duodenales
EP2995312A1 (de) * 2003-03-27 2016-03-16 SantoSolve AS Entzündungshemmende zusammensetzung auf der basis von strontiumverbindungen
CA2524610C (en) * 2003-05-07 2014-03-25 Osteologix A/S Strontium combinations for prophylaxis/treatment of cartilage and/or bone conditions
PL1534305T3 (pl) * 2003-05-07 2007-03-30 Osteologix As Leczenie zaburzeń chrząstek i kości solami strontu rozpuszczalnymi w wodzie
EP1622629B1 (de) * 2003-05-07 2013-07-10 Osteologix A/S Strontiumzubereitung mit kontrollierter Freisetzung
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
KR101165614B1 (ko) * 2004-02-26 2012-07-18 오스테올로지스 에이에스 괴사성 골 질환의 예방 또는 치료에 사용하기 위한스트론튬 함유 화합물
EP1744770A2 (de) * 2004-05-06 2007-01-24 Osteologix A/S Schnelle synthesemethoden mit hoher ausbeute zur herstellung von metallorganischen salzen
CA2570389A1 (en) * 2004-06-17 2005-12-29 Osteologix A/S Treatments comprising strontium for rheumatic and arthritic diseases and pain
CA2570503A1 (en) * 2004-06-17 2005-12-29 Osteologix A/S A method of improving the medical treatment of pain
US7618651B2 (en) * 2004-06-24 2009-11-17 Idexx Laboratories Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
US8658206B2 (en) * 2004-06-25 2014-02-25 Mokwalo SA Compositions comprising strontium and vitamin D and uses thereof
CN101018586B (zh) * 2004-06-25 2014-08-27 莫克瓦洛Spf有限公司 含锶和维生素d的组合物及其用途
FR2875807B1 (fr) * 2004-09-30 2006-11-17 Servier Lab Forme cristalline alpha du ranelate de strontium, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
LT2801354T (lt) * 2004-10-08 2017-06-26 Forward Pharma A/S Kontroliuojamo atpalaidavimo farmacinės kompozicijos, apimančios fumaro rūgšties esterį
US20080004344A1 (en) * 2004-11-10 2008-01-03 Aditech Pharma Ab Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use
EP1855654A1 (de) * 2005-02-28 2007-11-21 Osteologix A/S Tabletten mit hoher strontiumladung
FR2899895B1 (fr) * 2006-04-12 2010-09-17 Servier Lab Nouveaux sels de strontium d'acides sulfoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2029184B1 (de) 2006-05-26 2011-02-23 Baxter International Inc. Injizierbare fibrin-zusammensetzung zur knochenverstärkung
GB0612028D0 (en) * 2006-06-16 2006-07-26 Imp Innovations Ltd Bioactive glass
US20070292535A1 (en) * 2006-06-19 2007-12-20 Tabbiner Philip S Strontium compositions and methods of treating arthritic and or osteoporitic conditions
US20070292529A1 (en) * 2006-06-19 2007-12-20 Tabbiner Philip S Strontium compositions and methods of treating osteoporotic conditions
CN101204375B (zh) * 2006-12-19 2010-09-29 北京德众万全药物技术开发有限公司 一种雷奈酸锶干混悬剂
JP5907656B2 (ja) * 2007-04-23 2016-04-26 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated ストロンチウム化合物を含むフィブリン組成物
GB0713094D0 (en) * 2007-07-05 2007-08-15 Imp Innovations Ltd Glass polycarboxylate cements
GB0724556D0 (en) * 2007-12-17 2008-01-30 Queen Mary & Westfield College LAtency associated protein construct with aggrecanase sensitive cleavage site
JP5569398B2 (ja) 2008-02-29 2014-08-13 フェッローサン メディカル ディバイス エー/エス 止血および/または創傷治癒を促進するための装置
AU2009252995A1 (en) * 2008-05-27 2009-12-03 Imperial Innovations Limited Process for producing porous scaffolds from sinterable glass
GB0809592D0 (en) * 2008-05-27 2008-07-02 Imp Innovations Ltd Biomaterials
US8906420B2 (en) 2009-01-09 2014-12-09 Forward Pharma A/S Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix
GB0911365D0 (en) 2009-06-30 2009-08-12 Bioceramic Therapeutics Ltd Multicomponent glasses for use as coatings and in personal care products
FR2953139B1 (fr) 2009-11-27 2012-04-13 Servier Lab Composition pharmaceutique comprenant un sel de strontium, de la vitamine d et une cyclodextrine
WO2011110597A1 (de) 2010-03-11 2011-09-15 Azad Pharmaceutical Ingredients Ag Verfahren zur herstellung von strontiumranelat
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
KR101957625B1 (ko) 2010-06-01 2019-03-12 백스터 인터내셔널 인코포레이티드 건조 및 안정한 지혈 조성물의 제조 방법
EP2530068A1 (de) 2011-05-31 2012-12-05 Lacer, S.A. Neue Strontiumsalze, deren Synthese und Verwendung bei der Behandlung von Osteoporose
CA2851338C (en) 2011-10-11 2019-11-05 Baxter International Inc. Hemostatic compositions
JP6195569B2 (ja) 2011-10-11 2017-09-13 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 止血組成物
DK2771027T3 (en) 2011-10-27 2015-11-02 Baxter Int hemostatic compositions
CA2865349C (en) 2012-03-06 2021-07-06 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
CA2874290C (en) 2012-06-12 2020-02-25 Ferrosan Medical Devices A/S Dry haemostatic composition
CN105358071B (zh) 2013-06-21 2018-07-31 弗罗桑医疗设备公司 真空膨胀的干组合物和用于保留该干组合物的注射器
CA2928963C (en) 2013-12-11 2020-10-27 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
WO2016058612A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
EP3237041B1 (de) 2014-12-24 2020-01-29 Ferrosan Medical Devices A/S Spritze für die enthaltung und die mischung erster und zweiter substanzen
BR112017027695A2 (pt) 2015-07-03 2018-09-04 Ferrosan Medical Devices As seringa para retenção e mistura de primeira e segunda substâncias
WO2018084959A2 (en) * 2016-09-30 2018-05-11 Nelson Deanna J Pharmaceutical quality strontium l-lactate
MX2020011866A (es) 2018-05-09 2021-01-20 Ferrosan Medical Devices As Metodo para preparar una composicion hemostatica.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4152431A (en) * 1977-09-22 1979-05-01 William H. Rorer, Inc. Compositions and method of use
FR2633619B1 (fr) * 1988-06-29 1991-02-08 Adir Nouveau sel de strontium, son procede de preparation et les compositions pharmaceutiques le renfermant
FR2651497B1 (fr) * 1989-09-01 1991-10-25 Adir Nouveaux sels de metaux bivalents de l'acide n, n-di (carboxymethyl)amino-2 cyano-3 carboxymethyl-4 carboxy-5 thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Also Published As

Publication number Publication date
DE69719408D1 (de) 2003-04-10
FR2749759B1 (fr) 1999-11-26
ZA975323B (en) 1998-01-14
US5856356A (en) 1999-01-05
CN1136856C (zh) 2004-02-04
NO972764L (no) 1997-12-18
CA2206837A1 (fr) 1997-12-17
HUP9701059A2 (hu) 1998-03-02
NZ328106A (en) 2001-04-27
HU9701059D0 (en) 1997-08-28
ATE233558T1 (de) 2003-03-15
CN1179944A (zh) 1998-04-29
JPH1059852A (ja) 1998-03-03
DK0813869T3 (da) 2003-06-02
EP0813869A1 (de) 1997-12-29
FR2749759A1 (fr) 1997-12-19
NO315840B1 (no) 2003-11-03
HU227935B1 (en) 2012-06-28
ES2193337T3 (es) 2003-11-01
EP0813869B1 (de) 2003-03-05
HUP9701059A3 (en) 1998-05-28
NO972764D0 (no) 1997-06-16
AU711950B2 (en) 1999-10-28
CA2206837C (fr) 2002-12-03
JP3935557B2 (ja) 2007-06-27
AU2490297A (en) 1998-01-08
BR9703603A (pt) 1998-09-01

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Legal Events

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8364 No opposition during term of opposition