DE69711765T2 - Phrothrombin und Thrombin bindende Peptide. - Google Patents
Phrothrombin und Thrombin bindende Peptide.Info
- Publication number
- DE69711765T2 DE69711765T2 DE69711765T DE69711765T DE69711765T2 DE 69711765 T2 DE69711765 T2 DE 69711765T2 DE 69711765 T DE69711765 T DE 69711765T DE 69711765 T DE69711765 T DE 69711765T DE 69711765 T2 DE69711765 T2 DE 69711765T2
- Authority
- DE
- Germany
- Prior art keywords
- thrombin
- peptide
- seq
- leu
- gly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 239000001044 red dye Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 239000003001 serine protease inhibitor Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000012622 synthetic inhibitor Substances 0.000 description 1
- 108010031354 thermitase Proteins 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6429—Thrombin (3.4.21.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/672,805 US5831003A (en) | 1996-06-28 | 1996-06-28 | Peptides which bind to prothrombin and thrombin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69711765D1 DE69711765D1 (de) | 2002-05-16 |
| DE69711765T2 true DE69711765T2 (de) | 2002-10-02 |
Family
ID=24700072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69711765T Expired - Lifetime DE69711765T2 (de) | 1996-06-28 | 1997-06-16 | Phrothrombin und Thrombin bindende Peptide. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5831003A (https=) |
| EP (1) | EP0816377B1 (https=) |
| JP (1) | JP3978258B2 (https=) |
| AT (1) | ATE215964T1 (https=) |
| AU (1) | AU712575B2 (https=) |
| CA (1) | CA2206663A1 (https=) |
| DE (1) | DE69711765T2 (https=) |
| DK (1) | DK0816377T3 (https=) |
| ES (1) | ES2175218T3 (https=) |
| PT (1) | PT816377E (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6462180B1 (en) * | 1999-11-24 | 2002-10-08 | Bayer Corporation | Method of preparing α-1 proteinase inhibitor |
| ES2543829T5 (es) | 2000-12-14 | 2023-07-13 | Grifols Therapeutics Inc | Procedimiento para la preparación del inhibidor de proteinasa alfa 1 |
| GB0211849D0 (en) * | 2002-05-23 | 2002-07-03 | Mok Kenneth H | Improvments to retro-inverso isomers |
| FR2884418B1 (fr) * | 2005-04-15 | 2008-11-21 | Soc Extraction Principes Actif | Utilisation d'un peptide comme principe actif amincissant |
| CA2655933C (en) | 2006-06-23 | 2014-09-09 | Alethia Biotherapeutics Inc. | Polynucleotides and polypeptide sequences involved in cancer |
| KR20110084280A (ko) | 2008-11-03 | 2011-07-21 | 알레시아 바이오쎄라퓨틱스 인코포레이티드 | 종양 항원의 생물 활성을 특이적으로 차단하는 항체 |
| US8945895B2 (en) | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| RS59080B1 (sr) | 2011-03-31 | 2019-09-30 | Adc Therapeutics Sa | Antitela protiv antigena 1 povezanog sa bubrezima i njihovi fragmenti koji se vezuju za antigen |
| HRP20190946T1 (hr) | 2012-01-09 | 2019-07-26 | Adc Therapeutics Sa | Sredstva za liječenje trostruko negativnog raka dojke |
| CN107406840B (zh) | 2015-02-25 | 2021-05-28 | 奥姆里克斯生物药品有限公司 | 用于纯化和定量凝血酶及其降解多肽的方法 |
| ES2791982T3 (es) * | 2015-02-25 | 2020-11-06 | Omrix Biopharmaceuticals Ltd | Método para purificar y cuantificar la trombina y sus polipéptidos de degradación |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1341032C (en) * | 1987-01-23 | 2000-06-20 | John L. Krstenansky | Anticoagulant peptides |
| US5367060A (en) * | 1991-05-24 | 1994-11-22 | Genentech, Inc. | Structure, production and use of heregulin |
-
1996
- 1996-06-28 US US08/672,805 patent/US5831003A/en not_active Expired - Lifetime
-
1997
- 1997-06-16 DK DK97109744T patent/DK0816377T3/da active
- 1997-06-16 AT AT97109744T patent/ATE215964T1/de active
- 1997-06-16 ES ES97109744T patent/ES2175218T3/es not_active Expired - Lifetime
- 1997-06-16 EP EP97109744A patent/EP0816377B1/en not_active Expired - Lifetime
- 1997-06-16 DE DE69711765T patent/DE69711765T2/de not_active Expired - Lifetime
- 1997-06-16 PT PT97109744T patent/PT816377E/pt unknown
- 1997-06-23 AU AU26220/97A patent/AU712575B2/en not_active Ceased
- 1997-06-24 JP JP18189597A patent/JP3978258B2/ja not_active Expired - Fee Related
- 1997-06-25 CA CA002206663A patent/CA2206663A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU712575B2 (en) | 1999-11-11 |
| PT816377E (pt) | 2002-08-30 |
| EP0816377A3 (en) | 1998-07-15 |
| JPH1075778A (ja) | 1998-03-24 |
| DK0816377T3 (da) | 2002-07-22 |
| CA2206663A1 (en) | 1997-12-28 |
| DE69711765D1 (de) | 2002-05-16 |
| ATE215964T1 (de) | 2002-04-15 |
| JP3978258B2 (ja) | 2007-09-19 |
| US5831003A (en) | 1998-11-03 |
| ES2175218T3 (es) | 2002-11-16 |
| EP0816377A2 (en) | 1998-01-07 |
| EP0816377B1 (en) | 2002-04-10 |
| AU2622097A (en) | 1998-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |