DK0816377T3 - Peptider, som binder sig til prothrombin og thrombin - Google Patents

Peptider, som binder sig til prothrombin og thrombin

Info

Publication number
DK0816377T3
DK0816377T3 DK97109744T DK97109744T DK0816377T3 DK 0816377 T3 DK0816377 T3 DK 0816377T3 DK 97109744 T DK97109744 T DK 97109744T DK 97109744 T DK97109744 T DK 97109744T DK 0816377 T3 DK0816377 T3 DK 0816377T3
Authority
DK
Denmark
Prior art keywords
leu
gly
peptides
thrombin
tyr
Prior art date
Application number
DK97109744T
Other languages
English (en)
Inventor
Joseph A Buettner
Christopher A Dadd
David J Hammond
George A Baumbach
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0816377T3 publication Critical patent/DK0816377T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
DK97109744T 1996-06-28 1997-06-16 Peptider, som binder sig til prothrombin og thrombin DK0816377T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/672,805 US5831003A (en) 1996-06-28 1996-06-28 Peptides which bind to prothrombin and thrombin

Publications (1)

Publication Number Publication Date
DK0816377T3 true DK0816377T3 (da) 2002-07-22

Family

ID=24700072

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97109744T DK0816377T3 (da) 1996-06-28 1997-06-16 Peptider, som binder sig til prothrombin og thrombin

Country Status (10)

Country Link
US (1) US5831003A (da)
EP (1) EP0816377B1 (da)
JP (1) JP3978258B2 (da)
AT (1) ATE215964T1 (da)
AU (1) AU712575B2 (da)
CA (1) CA2206663A1 (da)
DE (1) DE69711765T2 (da)
DK (1) DK0816377T3 (da)
ES (1) ES2175218T3 (da)
PT (1) PT816377E (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6462180B1 (en) * 1999-11-24 2002-10-08 Bayer Corporation Method of preparing α-1 proteinase inhibitor
AU2001245240A1 (en) 2000-12-14 2002-06-24 Talecris Biotherapeutics, Inc. Method of preparing alpha-1 proteinase inhibitor
GB0211849D0 (en) * 2002-05-23 2002-07-03 Mok Kenneth H Improvments to retro-inverso isomers
FR2884418B1 (fr) * 2005-04-15 2008-11-21 Soc Extraction Principes Actif Utilisation d'un peptide comme principe actif amincissant
DK2032701T3 (da) 2006-06-23 2014-02-10 Alethia Biotherapeutics Inc Polynukleotider og polypeptider, der er inddraget i cancer
MX336869B (es) 2008-11-03 2016-02-04 Alethia Biotherapeutics Inc Anticuerpos que bloquean espicificamente la actividad biologica de un antigeno de tumor.
US8945895B2 (en) 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
HUE045943T2 (hu) 2011-03-31 2020-02-28 Adc Therapeutics Sa Veseasszociált antigén 1 és antigénkötõ fragmensei elleni antitestek
AU2013209234B2 (en) 2012-01-09 2017-11-09 Adc Therapeutics Sa Method for treating breast cancer
ES2791982T3 (es) * 2015-02-25 2020-11-06 Omrix Biopharmaceuticals Ltd Método para purificar y cuantificar la trombina y sus polipéptidos de degradación

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
US5367060A (en) * 1991-05-24 1994-11-22 Genentech, Inc. Structure, production and use of heregulin

Also Published As

Publication number Publication date
JPH1075778A (ja) 1998-03-24
AU712575B2 (en) 1999-11-11
DE69711765D1 (de) 2002-05-16
EP0816377B1 (en) 2002-04-10
ES2175218T3 (es) 2002-11-16
EP0816377A2 (en) 1998-01-07
US5831003A (en) 1998-11-03
DE69711765T2 (de) 2002-10-02
JP3978258B2 (ja) 2007-09-19
CA2206663A1 (en) 1997-12-28
EP0816377A3 (en) 1998-07-15
PT816377E (pt) 2002-08-30
AU2622097A (en) 1998-01-15
ATE215964T1 (de) 2002-04-15

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