PT816377E - Peptideos que se ligam a protrombina e a trombina - Google Patents

Peptideos que se ligam a protrombina e a trombina

Info

Publication number
PT816377E
PT816377E PT97109744T PT97109744T PT816377E PT 816377 E PT816377 E PT 816377E PT 97109744 T PT97109744 T PT 97109744T PT 97109744 T PT97109744 T PT 97109744T PT 816377 E PT816377 E PT 816377E
Authority
PT
Portugal
Prior art keywords
leu
gly
tyr
trp
pro
Prior art date
Application number
PT97109744T
Other languages
English (en)
Inventor
George A Baumbach
Joseph A Buettner
Christopher A Dadd
David J Hammond
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PT816377E publication Critical patent/PT816377E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
PT97109744T 1996-06-28 1997-06-16 Peptideos que se ligam a protrombina e a trombina PT816377E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/672,805 US5831003A (en) 1996-06-28 1996-06-28 Peptides which bind to prothrombin and thrombin

Publications (1)

Publication Number Publication Date
PT816377E true PT816377E (pt) 2002-08-30

Family

ID=24700072

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97109744T PT816377E (pt) 1996-06-28 1997-06-16 Peptideos que se ligam a protrombina e a trombina

Country Status (10)

Country Link
US (1) US5831003A (pt)
EP (1) EP0816377B1 (pt)
JP (1) JP3978258B2 (pt)
AT (1) ATE215964T1 (pt)
AU (1) AU712575B2 (pt)
CA (1) CA2206663A1 (pt)
DE (1) DE69711765T2 (pt)
DK (1) DK0816377T3 (pt)
ES (1) ES2175218T3 (pt)
PT (1) PT816377E (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6462180B1 (en) * 1999-11-24 2002-10-08 Bayer Corporation Method of preparing α-1 proteinase inhibitor
PT1343809E (pt) 2000-12-14 2015-09-22 Grifols Therapeutics Inc Método de preparação de inibidor de proteinase alfa-1
GB0211849D0 (en) * 2002-05-23 2002-07-03 Mok Kenneth H Improvments to retro-inverso isomers
FR2884418B1 (fr) * 2005-04-15 2008-11-21 Soc Extraction Principes Actif Utilisation d'un peptide comme principe actif amincissant
JP5564249B2 (ja) 2006-06-23 2014-07-30 アレシア・バイオセラピューティクス・インコーポレーテッド 癌に関与するポリヌクレオチド配列およびポリペプチド配列
BRPI0921805A2 (pt) 2008-11-03 2016-11-01 Alethia Biotherapeutics Inc anticorpos que especificamente bloqueiam a atividade biológica de um antígeno de tumor
US8945895B2 (en) 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
CN106146664B (zh) 2011-03-31 2021-09-07 Adc治疗股份有限公司 针对肾相关抗原1的抗体及其抗原结合片段
SI2802351T1 (sl) 2012-01-09 2019-07-31 ADC Therapeutics SA, Biopole Sredstva za zdravljenje trojno negativnega raka dojke
ES2791982T3 (es) * 2015-02-25 2020-11-06 Omrix Biopharmaceuticals Ltd Método para purificar y cuantificar la trombina y sus polipéptidos de degradación

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
US5367060A (en) * 1991-05-24 1994-11-22 Genentech, Inc. Structure, production and use of heregulin

Also Published As

Publication number Publication date
JP3978258B2 (ja) 2007-09-19
EP0816377B1 (en) 2002-04-10
EP0816377A3 (en) 1998-07-15
DK0816377T3 (da) 2002-07-22
DE69711765T2 (de) 2002-10-02
CA2206663A1 (en) 1997-12-28
DE69711765D1 (de) 2002-05-16
US5831003A (en) 1998-11-03
ES2175218T3 (es) 2002-11-16
EP0816377A2 (en) 1998-01-07
AU712575B2 (en) 1999-11-11
ATE215964T1 (de) 2002-04-15
AU2622097A (en) 1998-01-15
JPH1075778A (ja) 1998-03-24

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