DE69638142D1 - Regulierte Gene und ihre Verwendungen - Google Patents

Regulierte Gene und ihre Verwendungen

Info

Publication number
DE69638142D1
DE69638142D1 DE69638142T DE69638142T DE69638142D1 DE 69638142 D1 DE69638142 D1 DE 69638142D1 DE 69638142 T DE69638142 T DE 69638142T DE 69638142 T DE69638142 T DE 69638142T DE 69638142 D1 DE69638142 D1 DE 69638142D1
Authority
DE
Germany
Prior art keywords
regulated genes
protein
therapy
mitogenic activity
purposes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69638142T
Other languages
German (de)
English (en)
Inventor
Salvatore Oliviero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universita degli Studi di Siena
Original Assignee
Universita degli Studi di Siena
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26307843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69638142(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9519928.7A external-priority patent/GB9519928D0/en
Priority claimed from GBGB9612368.2A external-priority patent/GB9612368D0/en
Application filed by Universita degli Studi di Siena filed Critical Universita degli Studi di Siena
Application granted granted Critical
Publication of DE69638142D1 publication Critical patent/DE69638142D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69638142T 1995-09-29 1996-09-30 Regulierte Gene und ihre Verwendungen Expired - Lifetime DE69638142D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9519928.7A GB9519928D0 (en) 1995-09-29 1995-09-29 Regulated genes and uses thereof
GBGB9612368.2A GB9612368D0 (en) 1996-06-13 1996-06-13 Regulated genes and uses thereof

Publications (1)

Publication Number Publication Date
DE69638142D1 true DE69638142D1 (de) 2010-04-15

Family

ID=26307843

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69638142T Expired - Lifetime DE69638142D1 (de) 1995-09-29 1996-09-30 Regulierte Gene und ihre Verwendungen
DE69634412T Expired - Lifetime DE69634412T3 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69634412T Expired - Lifetime DE69634412T3 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen

Country Status (11)

Country Link
US (1) US8383788B2 (enExample)
EP (2) EP0853668B2 (enExample)
JP (1) JP4086315B2 (enExample)
AT (2) ATE290077T1 (enExample)
AU (1) AU7142996A (enExample)
CA (1) CA2230957A1 (enExample)
DE (2) DE69638142D1 (enExample)
ES (2) ES2239338T5 (enExample)
IL (1) IL123649A0 (enExample)
NO (1) NO981353D0 (enExample)
WO (1) WO1997012972A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6824777B1 (en) 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
US7423125B2 (en) 1995-08-01 2008-09-09 Vegenics Limited Antibodies to VEGF-C
AU710696C (en) 1995-09-08 2002-10-24 Genentech Inc. VEGF-related protein
JP4086315B2 (ja) 1995-09-29 2008-05-14 ユニベルシタ デグリ スチュディ ディ シエナ 調節遺伝子およびその使用
WO1998002543A1 (fr) 1996-07-15 1998-01-22 Chugai Research Institute For Molecular Medicine, Inc. Nouveaux facteurs analogues au vegf
DK1749836T3 (da) * 1996-08-23 2009-08-31 Vegenics Ltd Rekombinant vaskulær endothelcellevækstfaktor D
AU5439998A (en) * 1996-12-06 1998-06-29 Zymogenetics Inc. Vascular endothelial growth factor
US7125714B2 (en) 1997-02-05 2006-10-24 Licentia Ltd. Progenitor cell materials and methods
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
DE69839529D1 (de) * 1997-12-24 2008-07-03 Ludwig Inst Cancer Res Expressionsvektoren und zellinien zur expression von vaskulärem wachstumsfaktor d, sowie verfahren zur behandlung von melanomen
DE19847422C1 (de) * 1998-10-14 2000-01-13 Forschungszentrum Juelich Gmbh Chinese-Hamster-Ovary-Zellen zur Produktion von Proteinen
CA2354325C (en) 1998-12-07 2011-08-16 Zymogenetics, Inc. Growth factor homolog zvegf3
WO2001012669A1 (en) * 1999-08-16 2001-02-22 Universita' Degli Studi Di Siena Vegf-d and angiogenic use thereof
ATE377081T1 (de) 2000-02-25 2007-11-15 Ludwig Inst Cancer Res Material und verfahren die hybridvaskularendothelwachstumfaktoren dns und proteine enthalten und screeningverfahren für modulatoren
US7611711B2 (en) 2001-01-17 2009-11-03 Vegenics Limited VEGFR-3 inhibitor materials and methods
CA2435503C (en) 2001-01-19 2011-02-22 Ludwig Institute For Cancer Research Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy
CA2453161A1 (en) * 2001-07-12 2003-01-23 Ludwig Institute For Cancer Research Lymphatic endothelial cells materials and methods
US20030113324A1 (en) * 2001-10-01 2003-06-19 Kari Alitalo Neuropilin/VEGF-C/VEGFR-3 materials and methods
US20040214766A1 (en) * 2001-10-01 2004-10-28 Kari Alitalo VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
US20040248796A1 (en) * 2003-02-04 2004-12-09 Kari Alitalo VEGF-B and PDGF modulation of stem cells
WO2005011722A2 (en) * 2003-06-12 2005-02-10 Ludwig Institute For Cancer Research Use of vegf-c or vegf-d in reconstructive surgery
US20050032697A1 (en) * 2003-06-12 2005-02-10 Kari Alitalo Heparin binding VEGFR-3 ligands
WO2005087177A2 (en) 2004-03-05 2005-09-22 Ludwig Institute For Cancer Research Chimeric anti-vegf-d antibodies and humanized anti-vegf-d antibodies and methods of using same
ITRM20050367A1 (it) * 2005-07-08 2007-01-09 Univ Siena Uso del vegf-d o di suoi frammenti funzionalmente attivi per la ricostruzione o per la riparazione ossea.
EP1919944B1 (en) 2005-08-15 2011-03-23 Vegenics Pty Ltd Modified vegf and pdgf with improved angiogenic properties
US9073997B2 (en) 2007-02-02 2015-07-07 Vegenics Pty Limited Growth factor antagonists for organ transplant alloimmunity and arteriosclerosis
US8571840B2 (en) * 2007-03-28 2013-10-29 Autodesk, Inc. Constraint reduction for dynamic simulation
WO2011154308A1 (en) 2010-06-08 2011-12-15 Proyecto De Biomedicina Cima, S.L. New compositions and cell therapy methods for the treatment of cirrhosis
RU2014129392A (ru) 2012-01-06 2016-02-27 Эмболайн, Инк. Встроенные устройства противоэмболической защиты
AU2014218318B2 (en) 2013-02-18 2018-02-15 Vegenics Pty Limited Ligand binding molecules and uses thereof
EP3341397B1 (en) * 2015-08-25 2024-12-18 Histide AG Compounds for inducing tissue formation and uses thereof
AU2016311298A1 (en) 2015-08-25 2018-02-08 Histide Ag Compounds for inducing tissue formation and uses thereof
US10617509B2 (en) 2015-12-29 2020-04-14 Emboline, Inc. Multi-access intraprocedural embolic protection device
CN113677296B (zh) 2019-02-13 2024-12-31 艾姆伯莱恩公司 具有整合的栓塞防护装置的导管

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135983D0 (da) 1983-03-25 1983-03-25 Novo Industri As Maltogen amylaseenzymprodukt og fremgangsmade til dets fremstilling og anvendelse
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5968778A (en) * 1989-01-12 1999-10-19 Jurgen Hoppe PDGF-AB, preparation process and pharmaceuticals containing them
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
JP3024311B2 (ja) 1991-10-03 2000-03-21 味の素株式会社 Ｉｌ−２受容体重鎖に結合するポリペプチド
JPH05271294A (ja) 1992-01-24 1993-10-19 Japan Found Cancer Res ヒトプロヒビチンおよびそれをコードするｄｎａ
KR950702577A (ko) 1992-07-27 1995-07-29 알렌 제이. 스피겔 아젤레높시스 아페르타(agelenopsis aperta)로 부터의 칼슘 채널 차단 폴리펩티드(calcium channel blocking polypeptide from agelenopsis aperta)
DK0751992T3 (da) 1994-03-08 2006-03-06 Human Genome Sciences Inc Karendotelvækstfaktor 2
US5814464A (en) 1994-10-07 1998-09-29 Regeneron Pharma Nucleic acids encoding TIE-2 ligand-2
US6645933B1 (en) 1995-08-01 2003-11-11 Helsinki University Licensing Ltd. Oy Receptor ligand VEGF-C
US6221839B1 (en) * 1994-11-14 2001-04-24 Helsinki University Licensing Ltd. Oy FIt4 ligand and methods of use
JPH08185216A (ja) 1994-12-28 1996-07-16 Meidensha Corp 工具姿勢パラメータ設定方法及びロボット制御装置
US5928939A (en) 1995-03-01 1999-07-27 Ludwig Institute For Cancer Research Vascular endothelial growth factor-b and dna coding therefor
KR100414615B1 (ko) 1995-03-02 2004-05-27 암레드 오퍼레이션즈 피티와이, 리미티드 신규의증식인자및이를암호하는유전자서열
WO1996039421A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Human vascular endothelial growth factor 3
JP4086315B2 (ja) 1995-09-29 2008-05-14 ユニベルシタ デグリ スチュディ ディ シエナ 調節遺伝子およびその使用
WO1998002543A1 (fr) 1996-07-15 1998-01-22 Chugai Research Institute For Molecular Medicine, Inc. Nouveaux facteurs analogues au vegf
DK1749836T3 (da) * 1996-08-23 2009-08-31 Vegenics Ltd Rekombinant vaskulær endothelcellevækstfaktor D
AU5439998A (en) 1996-12-06 1998-06-29 Zymogenetics Inc. Vascular endothelial growth factor
US6262337B1 (en) 1997-02-18 2001-07-17 Ludwig Institute For Cancer Research Transgenic animal with recombinant vascular endothelial growth factor B (VEGF-B DNA) and uses thereof
PT1140175E (pt) * 1998-12-21 2006-06-30 Ludwig Inst Cancer Res Anticorpos para o vegf-d truncado e suas utilizacoes
WO2001012669A1 (en) * 1999-08-16 2001-02-22 Universita' Degli Studi Di Siena Vegf-d and angiogenic use thereof
CN104356177A (zh) 2008-02-12 2015-02-18 陶氏益农公司 杀虫组合物

Also Published As

Publication number Publication date
WO1997012972A3 (en) 1997-06-12
IL123649A0 (en) 1998-10-30
ES2341864T3 (es) 2010-06-29
DE69634412T3 (de) 2013-07-04
EP1553182A3 (en) 2008-03-05
JP4086315B2 (ja) 2008-05-14
DE69634412T2 (de) 2005-12-15
US8383788B2 (en) 2013-02-26
NO981353L (no) 1998-03-25
NO981353D0 (no) 1998-03-25
EP0853668A2 (en) 1998-07-22
US20020123481A1 (en) 2002-09-05
CA2230957A1 (en) 1997-04-10
ATE459715T1 (de) 2010-03-15
DE69634412D1 (de) 2005-04-07
EP0853668B1 (en) 2005-03-02
EP0853668B2 (en) 2013-03-06
JP2001501442A (ja) 2001-02-06
WO1997012972A2 (en) 1997-04-10
EP1553182B1 (en) 2010-03-03
EP1553182A2 (en) 2005-07-13
ES2239338T5 (es) 2013-05-31
ATE290077T1 (de) 2005-03-15
ES2239338T3 (es) 2005-09-16
AU7142996A (en) 1997-04-28

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Legal Events

Date Code Title Description
8363 Opposition against the patent