DE69623303T2 - Pufferzusammensetzung fur immunologische reagenzien - Google Patents

Pufferzusammensetzung fur immunologische reagenzien

Info

Publication number
DE69623303T2
DE69623303T2 DE69623303T DE69623303T DE69623303T2 DE 69623303 T2 DE69623303 T2 DE 69623303T2 DE 69623303 T DE69623303 T DE 69623303T DE 69623303 T DE69623303 T DE 69623303T DE 69623303 T2 DE69623303 T2 DE 69623303T2
Authority
DE
Germany
Prior art keywords
composition
acid
range
concentration
biological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69623303T
Other languages
German (de)
English (en)
Other versions
DE69623303D1 (de
Inventor
D. Figard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69623303D1 publication Critical patent/DE69623303D1/de
Publication of DE69623303T2 publication Critical patent/DE69623303T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/82Hepatitis associated antigens and antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/826Additives, e.g. buffers, diluents, preservatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
DE69623303T 1995-06-07 1996-05-24 Pufferzusammensetzung fur immunologische reagenzien Expired - Fee Related DE69623303T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/482,710 US5616460A (en) 1995-06-07 1995-06-07 Buffer composition for reagents for immunoassay
PCT/US1996/007745 WO1996041164A1 (en) 1995-06-07 1996-05-24 Buffer composition for reagents for immunoassay

Publications (2)

Publication Number Publication Date
DE69623303D1 DE69623303D1 (de) 2002-10-02
DE69623303T2 true DE69623303T2 (de) 2003-04-17

Family

ID=23917128

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69623303T Expired - Fee Related DE69623303T2 (de) 1995-06-07 1996-05-24 Pufferzusammensetzung fur immunologische reagenzien

Country Status (7)

Country Link
US (2) US5616460A (https=)
EP (1) EP0852009B1 (https=)
JP (2) JP4101874B2 (https=)
AT (1) ATE223046T1 (https=)
DE (1) DE69623303T2 (https=)
ES (1) ES2184866T3 (https=)
WO (1) WO1996041164A1 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171586B1 (en) 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
EP0999853B1 (en) * 1997-06-13 2003-01-02 Genentech, Inc. Stabilized antibody formulation
US6991790B1 (en) 1997-06-13 2006-01-31 Genentech, Inc. Antibody formulation
ATE417275T1 (de) 1997-09-22 2008-12-15 Novartis Vaccines & Diagnostic Puffern zur stabilizierung von hcv antigenen
AU9497998A (en) 1997-09-22 1999-04-12 Chiron Corporation Method for detecting antibodies in a sample
BRPI9909678B8 (pt) * 1998-04-17 2021-05-25 Fujirebio Europe N V aperfeiçoados ensaios de imunodiagnóstico usando agentes redutores
US6623921B2 (en) 1998-07-30 2003-09-23 Advanced Life Science Institute, Inc. Method for measurement of hepatitis C virus
US7316905B1 (en) 1998-07-30 2008-01-08 Advanced Life Science Institute, Inc. Method for measurement of hepatitis C virus
DE10013794A1 (de) * 2000-03-15 2001-10-11 Gluesenkamp Karl Heinz Herstellung, Stabilisierung und Anwendung einer neuen Art von chemisch aktivierten Oberflächen
AU2001273264A1 (en) * 2000-07-21 2002-02-05 Cuno, Incorporated Improved blocking chemistries for nylon membrane
AU2001287423B2 (en) * 2000-08-21 2007-04-05 Queen's University At Kingston Methods and kits for separation and detection of proteins in biological samples
US20030170618A1 (en) * 2001-02-02 2003-09-11 Chien David Y. Buffers for stabilizing antigens
AU785380B2 (en) * 2001-03-28 2007-03-15 Ortho-Clinical Diagnostics, Inc. A hepatitis C antigen - antibody combination assay for the early detection of HCV infection
JP2003066047A (ja) * 2001-06-14 2003-03-05 Matsushita Electric Ind Co Ltd 免疫反応測定方法及びそれに用いる免疫反応測定用試薬
US7101683B2 (en) 2001-06-26 2006-09-05 Abbott Laboratories Methods for the simultaneous detection of HCV antigens and HCV antibodies
CH698246B1 (de) * 2001-12-20 2009-06-30 Hoffmann La Roche Test zur Identifizierung von Inhibitoren von Beta-Sekretasen.
US20030157556A1 (en) * 2002-02-13 2003-08-21 Maggiore Jack A. Biological fluid stabilizing composition and method of use thereof
AU2003238767A1 (en) * 2002-05-31 2003-12-19 Penn State Research Foundation Dot-elisa for the detection of animal viruses
US20040152070A1 (en) * 2003-02-04 2004-08-05 Shah Dinesh O. Method of detection of HCV antibodies in combination assay or sole antibody assay
US20050014136A1 (en) * 2003-05-28 2005-01-20 Innogenetics N.V. Modified HCV NS5
CA2544185C (en) * 2003-10-28 2010-09-28 Advanced Life Science Institute, Inc. Method of detecting hepatitis c virus
CN104090097B (zh) * 2004-02-26 2017-04-12 康多尔生物技术有限公司 一种用作结合对的特异性结合反应培养基的水溶液
ATE476658T1 (de) 2004-02-26 2010-08-15 Candor Bioscience Gmbh Wässrige lösung zur verwendung als medium für die spezifischen bindungsreaktion eines bindespaares
US7867443B2 (en) * 2004-07-23 2011-01-11 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
US20080108147A1 (en) * 2006-11-03 2008-05-08 Tie Wei Reduction of non-specific binding in immunoassays
JP2007084579A (ja) * 2006-12-28 2007-04-05 Mitsubishi Pharma Corp ヘパリン溶液入りプレフィルドシリンジ製剤およびその製造方法
US8617820B2 (en) * 2007-08-28 2013-12-31 Ortho-Clinical Diagnostics, Inc. Use of glycosaminoglycans to reduce non-specific binding in immunoassays
JP5416159B2 (ja) * 2011-03-31 2014-02-12 富士フイルム株式会社 高感度なイムノクロマトグラフ方法
CN103630690B (zh) * 2013-12-17 2014-08-20 朱之炜 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法
WO2016127318A1 (zh) * 2015-02-10 2016-08-18 深圳市新产业生物医学工程股份有限公司 心肌肌钙蛋白i超敏检测试剂盒及其超敏检测方法
US12493034B2 (en) * 2021-01-08 2025-12-09 George Mason University Reagent buffer
CN114200125B (zh) * 2021-12-06 2024-02-13 武汉生之源生物科技股份有限公司 一种不含蛋白的碱性磷酸酶-抗体偶联物稀释液及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59198999A (ja) * 1983-04-27 1984-11-10 Denka Seiken Co Ltd クレアチンキナ−ゼ測定用組成物
JPS6339582A (ja) * 1986-08-04 1988-02-20 Takara Shuzo Co Ltd 酵素組成物
US4956274A (en) * 1987-04-06 1990-09-11 Microgenics Corporation Reagent stabilization in enzyme-donor and acceptor assay
US5075221A (en) * 1988-10-07 1991-12-24 Eastman Kodak Company Stabilized extraction composition containing a sulfhydryl-containing reducing agent and its use in chlamydial and gonococcal determinations
EP0401379B1 (en) * 1988-12-06 1994-06-15 Otsuka Pharmaceutical Co., Ltd. STABILIZED COMPOSITION OF INTERLEUKIN-1$g(b)
CA2079912C (en) * 1990-04-06 2000-07-11 Gregory Reyes Hepatitis c virus epitopes
AU2679492A (en) * 1991-09-16 1993-04-27 Abbott Laboratories Hepatitis c assay
US5376313A (en) * 1992-03-27 1994-12-27 Abbott Laboratories Injection molding a plastic assay cuvette having low birefringence
GR1001480B (el) * 1992-12-29 1994-02-28 Eyaggelia Protopapa Ενζυμικά σκευάσματα περιέχοντα παπαϊνη ή χυμο?ρυψίνη και μέ?οδοι μόνιμης ενζυμικής αποτρίχωσης.

Also Published As

Publication number Publication date
EP0852009A1 (en) 1998-07-08
JP2005300552A (ja) 2005-10-27
JP2001516440A (ja) 2001-09-25
JP4101874B2 (ja) 2008-06-18
WO1996041164A1 (en) 1996-12-19
JP3930519B2 (ja) 2007-06-13
DE69623303D1 (de) 2002-10-02
ES2184866T3 (es) 2003-04-16
EP0852009B1 (en) 2002-08-28
ATE223046T1 (de) 2002-09-15
US5773212A (en) 1998-06-30
US5616460A (en) 1997-04-01

Similar Documents

Publication Publication Date Title
DE69623303T2 (de) Pufferzusammensetzung fur immunologische reagenzien
DE69837703T2 (de) Methoden zum nachweis und zur analyse von virus
DE68924878T2 (de) Bestimmung eines felinen pathogen-specifischen Antikörpers und eines felinen pathogenen Antigens in einem Immuntest.
DE60019458T2 (de) Stabilisierendes verdünnungsmittel für polypeptide und antigene
DE69516007T2 (de) Verfahren zum nachweiss von antikörpern
EP0944832B1 (de) ANTIGENSPEZIFISCHER IgM-NACHWEIS
CN102426231B (zh) 一种免疫层析试条用封闭剂组合物以及一种免疫层析试条
DE69331845T3 (de) Immunoassays für anti-hcv-antikörper unter verwendung von antigenen mit konformationsepitopen
EP0481020B1 (en) Silver enhanced gold-labelled immuno assay method
EP0770679A2 (de) HCV-spezifische Peptide, Mittel dazu und ihre Verwendung
DE19649390A1 (de) Antigenspezifischer IgG-Nachweis
DE3930376A1 (de) Enzymimmunometrisches bestimmungsverfahren unter verwendung von peroxidase als markierungsenzym
EP0957360B1 (de) Entstörung durch Rheumafaktoren
DE69837155T2 (de) Verfahren zum nachweiss von antikörpern in einer probe
US4684609A (en) Method and substance for the enhanced labelling of cellular material
DE69016617T2 (de) Gepufferte Waschzusammensetzung, Zusammensetzung zur Unlöslichmachung, Testsätze und Verfahren zu ihrer Verwendung.
DE3532626A1 (de) Verfahren zur bestimmung eines partners einer immunreaktion
NZ210990A (en) Stabilised enzyme conjugate compositions containing polyethylene glycol
DE69822446T2 (de) Cyclosporin derivate und deren verwendung
DE69132257T2 (de) Verfahren zur Herstellung eines gereinigten Treponema-Antigens und dessen Verwendung
JP3993670B2 (ja) 感作金属コロイド試薬溶液の安定化方法および安定な感作金属コロイド試薬含有溶液
CA2221556C (en) Buffer composition for reagents for immunoassay
EP0763740A1 (de) Verfahren zur Bestimmung von Autoimmunphänomenen
DE69526143T2 (de) Abtrennfreier, spezifischer Bindungsassay mit Anti-Inhibitor-Antikörpern
DE69119445T2 (de) Analysemethode für infektiöse Pferdeanämie-Viren (EIA-Virus)

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee