DE69616027T2 - Verfahren zur herstellung von 4,6-dichloro-pyrimidine - Google Patents

Verfahren zur herstellung von 4,6-dichloro-pyrimidine

Info

Publication number
DE69616027T2
DE69616027T2 DE69616027T DE69616027T DE69616027T2 DE 69616027 T2 DE69616027 T2 DE 69616027T2 DE 69616027 T DE69616027 T DE 69616027T DE 69616027 T DE69616027 T DE 69616027T DE 69616027 T2 DE69616027 T2 DE 69616027T2
Authority
DE
Germany
Prior art keywords
pct
dichloropyrimidine
sec
dichloro
pyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69616027T
Other languages
English (en)
Other versions
DE69616027D1 (de
Inventor
Vincent Jones
John Whitton
Campbell Boyd
John Ritchie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Syngenta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9501738.0A external-priority patent/GB9501738D0/en
Priority claimed from GBGB9507787.1A external-priority patent/GB9507787D0/en
Priority claimed from GBGB9510751.2A external-priority patent/GB9510751D0/en
Application filed by Syngenta Ltd filed Critical Syngenta Ltd
Publication of DE69616027D1 publication Critical patent/DE69616027D1/de
Application granted granted Critical
Publication of DE69616027T2 publication Critical patent/DE69616027T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69616027T 1995-01-30 1996-01-04 Verfahren zur herstellung von 4,6-dichloro-pyrimidine Expired - Lifetime DE69616027T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9501738.0A GB9501738D0 (en) 1995-01-30 1995-01-30 Chemical process
GBGB9507787.1A GB9507787D0 (en) 1995-04-13 1995-04-13 Chemical process
GBGB9510751.2A GB9510751D0 (en) 1995-05-26 1995-05-26 Chemical process
PCT/GB1996/000013 WO1996023776A1 (en) 1995-01-30 1996-01-04 Process for preparing 4,6-dichloro-pyrimidine

Publications (2)

Publication Number Publication Date
DE69616027D1 DE69616027D1 (de) 2001-11-22
DE69616027T2 true DE69616027T2 (de) 2002-05-16

Family

ID=27267567

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69616027T Expired - Lifetime DE69616027T2 (de) 1995-01-30 1996-01-04 Verfahren zur herstellung von 4,6-dichloro-pyrimidine

Country Status (15)

Country Link
US (1) US6018045A (de)
EP (1) EP0807106B1 (de)
JP (1) JP3930903B2 (de)
KR (1) KR100406481B1 (de)
CN (1) CN1137099C (de)
AT (1) ATE207059T1 (de)
BR (1) BR9606817A (de)
DE (1) DE69616027T2 (de)
ES (1) ES2162019T3 (de)
GR (1) GR3036925T3 (de)
IL (1) IL116721A (de)
IN (1) IN184958B (de)
PT (1) PT807106E (de)
TW (1) TW343970B (de)
WO (1) WO1996023776A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9002375D0 (en) * 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
DE19531299A1 (de) * 1995-08-25 1997-02-27 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidinen
GB9709810D0 (en) * 1997-05-14 1997-07-09 Zeneca Ltd Chemical process
DE19730224A1 (de) * 1997-07-15 1999-01-21 Bayer Ag Verfahren zur Reinigung Phosphoroxychlorid
WO1999032458A1 (en) * 1997-12-19 1999-07-01 Dow Agrosciences Llc Chloropyrimidine process
DE19929350A1 (de) 1999-06-26 2000-12-28 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidin mit Säurechloriden
DE19929353A1 (de) * 1999-06-26 2000-12-28 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidin
DE19935322A1 (de) * 1999-07-28 2001-02-01 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidin mit Phosgen
US6608199B2 (en) 2000-07-07 2003-08-19 Syngenta Limited Synthesis of chlorinated pyrimidines
US6982331B2 (en) * 2001-06-08 2006-01-03 Syngenta Crop Protection, Inc. Synthesis of chlorinated pyrimidines
CN103482592B (zh) * 2013-09-13 2016-09-28 重庆紫光化工股份有限公司 一种含磷废液的处理方法
CN107324300A (zh) * 2013-09-13 2017-11-07 重庆紫光化工股份有限公司 一种含磷废液的体系
CN103450094B (zh) * 2013-09-13 2015-08-26 重庆紫光化工股份有限公司 一种4,6-二氯嘧啶的纯化方法
CN106045917A (zh) * 2016-07-19 2016-10-26 安徽广信农化股份有限公司 一步法制备4,6‑二氯嘧啶的合成工艺
CN106187912A (zh) * 2016-07-19 2016-12-07 安徽广信农化股份有限公司 一种4,6‑二氯嘧啶的生产工艺
CN111635367B (zh) * 2020-06-24 2023-05-30 山东京博农化科技股份有限公司 一种4,6-二氯嘧啶的纯化方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789763A (fr) * 1971-10-08 1973-04-06 Ciba Geigy Procede de regeneration de l'oxychlorure ou -bromure de phosphore a partir de melanges reactionnels
DE3228712A1 (de) * 1982-07-31 1984-02-02 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,4,5,6-tetrachlorpyrimidin
DE3431698A1 (de) * 1984-08-29 1986-03-13 Bayer Ag, 5090 Leverkusen 5,5-dichlor-4,5-dihydro-6-hydroxy-2-trichlormethyl-pyrimidin-4-on, ein verfahren zu seiner herstellung und seine verwendung
DE3441789A1 (de) * 1984-11-15 1986-05-15 Bayer Ag, 5090 Leverkusen 5,6-dichlor-4-hydroxy-2-trichlormethylpyrimidin
DE3441935A1 (de) * 1984-11-16 1986-05-28 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,4-dihydroxypyrimidinen
GB8916698D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel process
AU652968B2 (en) * 1990-10-09 1994-09-15 Neurogen Corporation Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a new class of gaba brain receptor ligands
DE4222518A1 (de) * 1992-07-09 1994-01-13 Bayer Ag Verfahren zur Hertellung von 5-(Trifluormethyl)-uracil und die neuen Verbindungen 2,4-Dichlor-5-trichlormethyl-pyrimidin und 2,4-Difluor-5-trifluormethyl-pyrimidin
GB9220585D0 (en) * 1992-09-30 1992-11-11 Smithkline Beecham Plc Pharmaceuticals
CN1082031A (zh) * 1993-05-20 1994-02-16 郑州市孝义制药厂 磺胺间甲氧嘧啶的制备方法
DE4408404A1 (de) * 1994-03-12 1995-09-14 Huels Chemische Werke Ag Verfahren zur Herstellung von Chlorpyrimidinen
DE4429466A1 (de) * 1994-08-19 1996-02-22 Bayer Ag Verfahren zur Herstellung von Polychlorpyrimidinen
AT402818B (de) * 1995-06-02 1997-09-25 Chemie Linz Gmbh Verfahren zur herstellung von reinem 4,6-dichlorpyrimidin
DE19531299A1 (de) * 1995-08-25 1997-02-27 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidinen

Also Published As

Publication number Publication date
CN1206408A (zh) 1999-01-27
GR3036925T3 (en) 2002-01-31
PT807106E (pt) 2002-02-28
IN184958B (de) 2000-10-07
EP0807106B1 (de) 2001-10-17
DE69616027D1 (de) 2001-11-22
BR9606817A (pt) 1997-12-30
CN1137099C (zh) 2004-02-04
ATE207059T1 (de) 2001-11-15
EP0807106A1 (de) 1997-11-19
KR100406481B1 (ko) 2004-03-24
JP3930903B2 (ja) 2007-06-13
JPH11507909A (ja) 1999-07-13
US6018045A (en) 2000-01-25
IL116721A (en) 2000-02-17
TW343970B (en) 1998-11-01
WO1996023776A1 (en) 1996-08-08
KR19980701747A (ko) 1998-06-25
ES2162019T3 (es) 2001-12-16
IL116721A0 (en) 1996-08-04

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SYNGENTA LTD., GUILDFORD, GB