DE69533197D1 - Liposomale mitteln - Google Patents

Liposomale mitteln

Info

Publication number
DE69533197D1
DE69533197D1 DE69533197T DE69533197T DE69533197D1 DE 69533197 D1 DE69533197 D1 DE 69533197D1 DE 69533197 T DE69533197 T DE 69533197T DE 69533197 T DE69533197 T DE 69533197T DE 69533197 D1 DE69533197 D1 DE 69533197D1
Authority
DE
Germany
Prior art keywords
liposomal
liposomal means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69533197T
Other languages
English (en)
Other versions
DE69533197T2 (de
Inventor
Martha Garrity
John Varadarajan
David Watson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amersham Health Salutar Inc
Original Assignee
Amersham Health Salutar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Health Salutar Inc filed Critical Amersham Health Salutar Inc
Application granted granted Critical
Publication of DE69533197D1 publication Critical patent/DE69533197D1/de
Publication of DE69533197T2 publication Critical patent/DE69533197T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1234—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69533197T 1994-10-10 1995-10-09 Liposomale Mittel Expired - Lifetime DE69533197T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9420390 1994-10-10
GB9420390A GB9420390D0 (en) 1994-10-10 1994-10-10 Liposomal agents
PCT/GB1995/002378 WO1996011023A1 (en) 1994-10-10 1995-10-09 Liposomal agents

Publications (2)

Publication Number Publication Date
DE69533197D1 true DE69533197D1 (de) 2004-07-29
DE69533197T2 DE69533197T2 (de) 2005-07-28

Family

ID=10762605

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69533197T Expired - Lifetime DE69533197T2 (de) 1994-10-10 1995-10-09 Liposomale Mittel

Country Status (10)

Country Link
US (1) US6045821A (de)
EP (1) EP0785804B1 (de)
JP (1) JP4057646B2 (de)
CN (1) CN1168636A (de)
AU (1) AU3613695A (de)
CA (1) CA2200867A1 (de)
DE (1) DE69533197T2 (de)
GB (1) GB9420390D0 (de)
MX (1) MX9702523A (de)
WO (1) WO1996011023A1 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern
US6093382A (en) 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
US6342598B1 (en) 1998-11-26 2002-01-29 Bracco International B.V. Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
HUP0200483A3 (en) * 1999-03-11 2004-07-28 Fujisawa Pharmaceutical Co Liposome preparations
US6479300B1 (en) * 1999-03-15 2002-11-12 Millipore Corporation Metal loaded ligand bound membranes for metal ion affinity chromatography
US6379698B1 (en) 1999-04-06 2002-04-30 Isis Pharmaceuticals, Inc. Fusogenic lipids and vesicles
AU784813B2 (en) 2000-01-17 2006-06-29 Bayer Aktiengesellschaft Substituted aryl ketones
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
PT1272507E (pt) 2000-04-12 2005-11-30 Amersham Health As Derivados de peptidos para ligacao a integrina
NO20004795D0 (no) 2000-09-26 2000-09-26 Nycomed Imaging As Peptidbaserte forbindelser
US20040077604A1 (en) * 2001-12-19 2004-04-22 Lenard Lichtenberger Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity
DE10109898A1 (de) 2001-02-21 2002-09-05 Novosom Gmbh Lipide mit veränderlicher Ladung
AU2002303146A1 (en) * 2001-03-22 2002-10-08 The Administrators Of The Tulane Educational Fund Biaryl monomers and dendritic polymers derived therefrom
ATE538206T1 (de) * 2001-04-17 2012-01-15 Danisco Us Inc Verfahren zur bindung von enzym an einen träger unter verwendung kationischer copolymere und damit hergestelltes produkt
GB0111279D0 (en) * 2001-05-10 2001-06-27 Nycomed Imaging As Radiolabelled liposomes
MXPA04000173A (es) 2001-07-10 2004-03-18 Amersham Health As Compuestos basados en peptidos.
EP1420831A1 (de) * 2001-07-27 2004-05-26 Targesome, Inc. Lipid-konstrukte als therapeutische und bildgebende mittel
US7087212B2 (en) * 2001-08-17 2006-08-08 Mallinckrodt, Inc Multicomponent assemblies having enhanced binding properties for diagnosis and therapy
ATE475411T1 (de) * 2001-10-03 2010-08-15 Celator Pharmaceuticals Inc Liposomenladung mit metallionen
US7381426B2 (en) * 2002-01-24 2008-06-03 Southwest Research Institute Targeted delivery of bioactive factors to the systemic skeleton
CA2475567A1 (en) * 2002-02-07 2003-08-14 Covalent Partners, Llc Nanofilm and membrane compositions
AU2003212974B2 (en) * 2002-02-07 2008-08-14 Covalent Partners, Llc Macrocyclic module compositions
US20040034223A1 (en) * 2002-02-07 2004-02-19 Covalent Partners, Llc. Amphiphilic molecular modules and constructs based thereon
US6869591B2 (en) * 2002-03-26 2005-03-22 Barnes-Jewish Hospital Paramagnetic particles that provide improved relaxivity
US7184663B2 (en) * 2002-05-29 2007-02-27 Fujitsu Limited Optical ring network with hub node and method
CN1245153C (zh) * 2002-06-06 2006-03-15 上海家化联合股份有限公司 一种维生素a脂质体及其制备方法
US20040106741A1 (en) * 2002-09-17 2004-06-03 Kriesel Joshua W. Nanofilm compositions with polymeric components
EP1466629A1 (de) * 2003-04-11 2004-10-13 BRACCO IMAGING S.p.A. Adducte zwischen NMR Vershibungsreagenzen und Substraten mit austauschbaren Protonen für die "CEST" Anwendung
US20040258614A1 (en) * 2003-06-20 2004-12-23 University Of Maryland, Baltimore Microparticles for microarterial imaging and radiotherapy
WO2005030711A2 (en) * 2003-08-06 2005-04-07 Covalent Partners Llc Bridged macrocyclic module compositions
JP2007512221A (ja) * 2003-11-21 2007-05-17 富士フイルム株式会社 疎水性キレート化合物を含有するリポソームを含む造影剤
TWI350183B (en) * 2003-12-31 2011-10-11 Ind Tech Res Inst A liposome and a preparation method
AU2005265163B2 (en) 2004-06-18 2009-10-01 Ambrx, Inc. Novel antigen-binding polypeptides and their uses
FR2875410B1 (fr) * 2004-09-23 2012-11-16 Guerbet Sa Composes de diagnostique pour le ciblage de recpteur a chimiokines
EP1793868B1 (de) * 2004-09-23 2010-12-29 Guerbet Liposomale kontrastmittel für die cest-bildgebung
EP1810688A1 (de) * 2004-11-10 2007-07-25 Konica Minolta Medical & Graphic, Inc. Pharmazeutische zubereitung mit beschichteten magnetischen teilchen und verfahren zu ihrer herstellung und diagnose- und therapiesystem
DE102005018330B4 (de) 2005-04-20 2007-04-19 Siemens Ag System zur Erzeugung von CT-Bilddatensätzen und zur Bestrahlung eines Tumor-Patienten
NO20052428D0 (no) * 2005-05-20 2005-05-20 Amersham Health As Kontrastmidler
AR059193A1 (es) 2006-01-31 2008-03-12 Bayer Schering Pharma Ag Modulacion de la actividad de mdl-1 para el tratamiento de enfermedades inflamatorias
NO329127B1 (no) * 2006-09-12 2010-08-30 Epitarget As Sporbart partikulaert materiale for legemiddelavlevering omfattende et matriseeller membranmateriale, et legemiddel, og et T1- og et T2*- magnetisk resonanskontrastmiddel
CN1962683A (zh) * 2006-12-18 2007-05-16 张文芳 聚乙二醇修饰的甾醇共聚物及其应用
FR2914304B1 (fr) 2007-03-28 2012-11-16 Guerbet Sa Composes pour le diagnostic de maladies liees a l'expression de vcam.
FR2914303A1 (fr) * 2007-03-28 2008-10-03 Guerbet Sa Composes pour le diagnostic de l'apoptose.
WO2008134289A2 (en) * 2007-04-26 2008-11-06 Mallinckrodt Inc. High relaxivity coordinatively unsaturated lanthanide complexes
WO2009039192A2 (en) 2007-09-17 2009-03-26 The Regents Of The University Of Californina Internalizing human monoclonal antibodies targeting prostate cancer cells in situ
US9801818B2 (en) * 2007-12-31 2017-10-31 Samyang Biopharmaceuticals Corporation Method for stabilizing amphiphilic block copolymer micelle composition containing poorly water-soluble drug
DE102008003615A1 (de) 2008-01-09 2009-07-16 Magforce Nanotechnologies Ag Magnetische Transducer
US20110200534A1 (en) * 2008-08-21 2011-08-18 Industry-Academic Cooperation Foundation, Yonsei U T1-T2 Dual Modal MRI Contrast Agents
JP5657902B2 (ja) * 2010-03-17 2015-01-21 株式会社コスモステクニカルセンター ポリオキシアルキレンステロールエーテル誘導体及び／又はポリオキシアルキレンスタノールエーテル誘導体、及びそれを含有する外用剤組成物
WO2011147926A2 (en) * 2010-05-26 2011-12-01 Erik Reimhult Magnetically responsive membrane structures
EP2684048B1 (de) 2011-03-11 2018-10-03 Board of Regents of the University of Nebraska Biomarker für koronare herzkrankheit
AU2012292554B2 (en) 2011-08-10 2014-10-30 Magforce Ag Agglomerating magnetic alkoxysilane-coated nanoparticles
KR102162901B1 (ko) 2011-09-29 2020-10-08 피엘엑스 옵코 인코포레이티드 위장관을 따라 약물을 표적화 방출하기 위한 pH 감응성 담체, 그로부터의 조성물, 및 이들의 제조 및 사용 방법
JP6230538B2 (ja) * 2012-08-10 2017-11-15 大鵬薬品工業株式会社 安定なオキサリプラチン封入リポソーム水分散液及びその安定化方法
US20150343079A1 (en) * 2012-10-25 2015-12-03 Sogang University Research Foundation Ultrasound contrast agent with nanoparticles including drug and method for preparing the same
EP2918262B1 (de) 2014-03-10 2023-08-09 PLS-Design GmbH Induktion einer antigenspezifischen Toleranz durch periphere Phagozytose
ES2704299T3 (es) * 2015-01-21 2019-03-15 Pacira Pharmaceuticals Inc Formulaciones de liposomas multivesiculares de ácido tranexámico
AU2016349577B2 (en) * 2015-11-06 2023-10-26 Wisconsin Alumni Research Foundation Long-lived gadolinium based tumor targeted imaging and therapy agents
PT3383920T (pt) 2015-11-30 2024-04-15 Univ California Entrega de carga útil específica para tumores e ativação imune utilizando um anticorpo humano que tem como alvo um antigénio altamente específico da superfície das células tumorais
CN105693807B (zh) * 2016-01-25 2018-06-12 四川大学 新型脑靶向脂质材料及其在药物传递系统中的应用
CN109789227B (zh) * 2016-07-25 2022-10-11 威斯康星校友研究基金会 用于癌症成像和疗法的放射性磷脂金属螯合物
CN109789207B (zh) * 2016-07-25 2022-11-18 威斯康星校友研究基金会 用于原位免疫调节的癌症疫苗接种的靶向放射治疗螯合物
WO2021195319A1 (en) 2020-03-26 2021-09-30 Plx Opco Inc. PHARMACEUTICAL CARRIERS CAPABLE OF pH DEPENDENT RECONSTITUTION AND- METHODS FOR MAKING AND USING SAME
BR112023002346A2 (pt) 2020-08-07 2023-05-02 Fortis Therapeutics Inc Imunoconjugados direcionados a cd46 e métodos de uso dos mesmos
CN112180079B (zh) * 2020-09-25 2024-04-19 上海睿康生物科技有限公司 一种稳定的脂质体颗粒及其在免疫比浊检测中的应用
US11980636B2 (en) 2020-11-18 2024-05-14 Jazz Pharmaceuticals Ireland Limited Treatment of hematological disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603044A (en) * 1983-01-06 1986-07-29 Technology Unlimited, Inc. Hepatocyte Directed Vesicle delivery system
GB8808305D0 (en) * 1988-04-08 1988-05-11 Nycomed As Compositions
GB8824593D0 (en) * 1988-10-20 1988-11-23 Royal Free Hosp School Med Liposomes
US5053503A (en) * 1989-02-17 1991-10-01 Centocor Chelating agents
GB9006977D0 (en) * 1990-03-28 1990-05-23 Nycomed As Compositions
AU660033B2 (en) * 1991-05-23 1995-06-08 Imarx Pharmaceutical Corp. Liposoluble compounds for magnetic resonance imaging
SE9101709L (sv) * 1991-06-03 1992-12-04 Karlshamns Lipidteknik Ab Lipidderivat som diagnostikum eller kontrastmedel
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
US5472605A (en) * 1994-03-10 1995-12-05 Hemasure, Inc. Filtration device useable for removal of leukocytes and other blood components
GB9407435D0 (en) * 1994-04-14 1994-06-08 Nycomed Salutar Inc Compounds

Also Published As

Publication number Publication date
DE69533197T2 (de) 2005-07-28
EP0785804B1 (de) 2004-06-23
CA2200867A1 (en) 1996-04-18
GB9420390D0 (en) 1994-11-23
US6045821A (en) 2000-04-04
MX9702523A (es) 1997-06-28
JP4057646B2 (ja) 2008-03-05
AU3613695A (en) 1996-05-02
WO1996011023A1 (en) 1996-04-18
CN1168636A (zh) 1997-12-24
JPH10507172A (ja) 1998-07-14
EP0785804A1 (de) 1997-07-30

Similar Documents

Publication Publication Date Title
DE69533197D1 (de) Liposomale mitteln
ATA166795A (de) Bis-resorcinyltriazine
ATA163695A (de) 2-hydroxyphenyltriazine
DE59501347D1 (de) Hydroxyphenylharnstoffe
DE59503633D1 (de) Zyklonsichter
BR9506519A (pt) Azatrioxaspiroalquenos
DE29501964U1 (de) Libelle
FI940632A0 (fi) Kombinerat braensle- och ellaos
FI944403A0 (fi) Stigkaelke II
FI1360U1 (fi) Justerbar inpassningsdetalj
FI1305U1 (fi) Foervaringsanordning
FI1428U1 (fi) Pelarfot
FI1464U1 (fi) Dykarhandske
ATE197372T1 (de) Vorteig
BR9400290A (pt) Selo-contrato
BR7400030U (pt) Numeralfa
BR9403309A (pt) Choppometro
BR9403098A (pt) Turnimetro
BR9402584A (pt) Chavecheque
BR9401966A (pt) Intervalômetro-foto ARJ-07
BR9401864A (pt) Pescoço-giratório
BR9401264A (pt) Prevgás
BR9401008A (pt) Helistato
BR9403758A (pt) Multiplic
BR9400287A (pt) Bi-vaso sanitário

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: HAMMONDS LLP, LONDON, GB

R082 Change of representative

Ref document number: 785804

Country of ref document: EP

Representative=s name: J D REYNOLDS & CO., GB