DE69532675D1 - Verfahren zum nachweis des antibiotikaresistenzspektrums von mykobakterium spezies - Google Patents

Verfahren zum nachweis des antibiotikaresistenzspektrums von mykobakterium spezies

Info

Publication number
DE69532675D1
DE69532675D1 DE69532675T DE69532675T DE69532675D1 DE 69532675 D1 DE69532675 D1 DE 69532675D1 DE 69532675 T DE69532675 T DE 69532675T DE 69532675 T DE69532675 T DE 69532675T DE 69532675 D1 DE69532675 D1 DE 69532675D1
Authority
DE
Germany
Prior art keywords
antibiotic resistance
sample
detecting
mycobacterium species
mycobacterium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69532675T
Other languages
English (en)
Other versions
DE69532675T2 (de
Inventor
Beenhouwer Hans De
Francoise Portaels
Lieve Machtelinckx
Geert Jannes
Rudi Rossau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Innogenetics NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8218646&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69532675(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA
Publication of DE69532675D1 publication Critical patent/DE69532675D1/de
Application granted granted Critical
Publication of DE69532675T2 publication Critical patent/DE69532675T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
DE69532675T 1994-06-09 1995-06-09 Verfahren zum nachweis des antibiotikaresistenzspektrums von mykobakterium spezies Expired - Lifetime DE69532675T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94870093 1994-06-09
EP94870093 1994-06-09
PCT/EP1995/002230 WO1995033851A2 (en) 1994-06-09 1995-06-09 Method for the detection of the antibiotic resistance spectrum of mycobacterium species

Publications (2)

Publication Number Publication Date
DE69532675D1 true DE69532675D1 (de) 2004-04-15
DE69532675T2 DE69532675T2 (de) 2005-02-24

Family

ID=8218646

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532675T Expired - Lifetime DE69532675T2 (de) 1994-06-09 1995-06-09 Verfahren zum nachweis des antibiotikaresistenzspektrums von mykobakterium spezies

Country Status (14)

Country Link
US (4) US6329138B1 (de)
EP (1) EP0771360B1 (de)
JP (1) JP4558105B2 (de)
AT (1) ATE261496T1 (de)
AU (1) AU703947B2 (de)
BR (1) BR9507960B8 (de)
CA (1) CA2192364C (de)
CZ (1) CZ298020B6 (de)
DE (1) DE69532675T2 (de)
DK (1) DK0771360T3 (de)
ES (1) ES2217280T3 (de)
PT (1) PT771360E (de)
RU (1) RU2204608C2 (de)
WO (1) WO1995033851A2 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9507960B8 (pt) * 1994-06-09 2014-09-30 Fujirebio Europ N V Processos e kits para deteção de resistência à rifampicina e/ou rifabutina de espécies de mycobacterium.
CA2284775C (en) 1997-04-15 2006-11-07 Ciba Specialty Chemicals Holding Inc. Preparation of low-dust stabilisers
DE19734940A1 (de) * 1997-08-12 1999-02-18 Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh Nucleinsäuremolekül-Satz für Salmonella-Nachweis, Nucleinsäuren, Kit und Verwendung
US7108968B2 (en) * 1998-04-03 2006-09-19 Affymetrix, Inc. Mycobacterial rpoB sequences
JP2002532103A (ja) * 1998-12-11 2002-10-02 ビジブル ジェネティクス インコーポレイテッド マイコバクテリウムツバキュロシスにおける抗生物質耐性変異の特徴付けのための方法及びキット
EP1076099A3 (de) * 1999-08-03 2003-03-05 Nisshinbo Industries, Inc. Kit zur Diagnose des Tuberkelbacillus
KR100363615B1 (ko) * 1999-10-27 2002-12-06 주식회사 제니스라이프사이언스 ｒｐｏＢ 유전자 단편 및 이를 이용한 결핵균과 비결핵마이코박테리아의 동정방법
EP1307587A2 (de) 2000-03-03 2003-05-07 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Multiplex hybridisierungsystem zur identifizierung pathogener mycobakterien sowie anwendungsverfahren
KR100451108B1 (ko) * 2000-05-30 2004-10-06 주식회사 바이오메드랩 마이코박테리아 균동정 및 약제내성 탐지를 위한 유전자진단키트 및 그 키트의 제조방법
AP2002002454A0 (en) * 2000-06-28 2002-06-30 Bakulesh Mafatlal Khamar Agents for reversal of drug resistance in mycobacterium tuberculosis.
US6902894B2 (en) * 2001-09-07 2005-06-07 Genetel Pharmaceuticals Ltd. Mutation detection on RNA polmerase beta subunit gene having rifampin resistance
US7094542B2 (en) * 2001-09-18 2006-08-22 Gen-Probe Incorporated Detection of rpoB sequences of Mycobacterium tuberculosis
WO2003025227A1 (en) * 2001-09-18 2003-03-27 Gen-Probe Incorporated Detection of rpob sequences of mycobacterium tuberculosis
KR100454585B1 (ko) * 2001-10-09 2004-11-02 주식회사 에스제이하이테크 마이코박테리아의 균주 감별, 결핵균의 스트레인 감별과항생제 내성을 검출하기 위한 프로브를 포함하는마이크로어레이와 이를 이용한 검출 방법 및 진단 키트
FI115637B (fi) * 2003-12-19 2005-06-15 Mobidiag Oy Diagnostinen menetelmä hengitystieinfektioita aiheuttavien bakteerien osoittamiseksi ja tunnistamiseksi ja menetelmässä käyttökelpoinen alukeseos
GB0403039D0 (en) * 2004-02-11 2004-03-17 Health Prot Agency TB resistance assay
US7445895B2 (en) * 2004-04-28 2008-11-04 Asiagen Corporation Methods, kits and assay system for detecting drug-resistant Mycobacterium tuberculosis
ITRM20050067A1 (it) * 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine.
ITRM20050068A1 (it) * 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine.
US7914982B2 (en) * 2005-02-17 2011-03-29 Trovagene, Inc. Methods for detecting pathogen specific nucleic acids in urine
RU2376387C2 (ru) * 2005-12-26 2009-12-20 Учреждение Российской академии наук Институт молекулярной биологии им. В.А. Энгельгардта РАН Способ одновременного обнаружения микобактерий туберкулезного комплекса и идентификации мутаций в днк микобактерий, приводящих к устойчивости микроорганизмов к рифампицину и изониазиду, на биологических микрочипах, набор праймеров, биочип и набор олигонуклеотидных зондов, используемые в способе
EP1992703B1 (de) * 2006-03-13 2012-04-11 Wako Pure Chemical Industries, Ltd. Verfahren zur erkennung eines mutierten gens
PL2195450T3 (pl) * 2007-08-22 2013-09-30 Trovagene Inc Sposób zastosowania miRNA do wykrywania in vivo śmierci komórki
US7946758B2 (en) * 2008-01-31 2011-05-24 WIMM Labs Modular movement that is fully functional standalone and interchangeable in other portable devices
JP2009189283A (ja) * 2008-02-13 2009-08-27 Nipro Corp 結核菌および非結核性抗酸菌検出試薬
KR101001368B1 (ko) * 2008-05-22 2010-12-14 엠앤디 (주) 나균 리팜핀 내성 진단용 프로브 및 그 키트
KR100990756B1 (ko) 2008-05-22 2010-10-29 엠앤디 (주) 결핵균 약제 내성 진단용 프로브 및 그 키트
ES2689257T3 (es) 2010-11-10 2018-11-12 Brandeis University Kit para la detección e identificación de micobacterias
TWI614345B (zh) * 2012-06-22 2018-02-11 Taichung Veterans General Hospital 檢測數種非結核分枝桿菌、結核分枝桿菌及其抗藥性之探針、晶片、套組與方法
RU2552214C2 (ru) * 2013-04-03 2015-06-10 Федеральное Государственное Бюджетное Учреждение науки Институт химический биологии и фундаментальной медицины Сибирского отделения РАН (ИХБФМ СО РАН) СПОСОБ ВЫЯВЛЕНИЯ УСТОЙЧИВЫХ К ПИРАЗИНАМИНУ ИЗОЛЯТОВ Mycobacterium tuberculosis
KR101472993B1 (ko) * 2013-08-20 2014-12-18 한국생명공학연구원 마이크로박테리움 속 hy-17 균주로부터 생산되는 신규한 알카리 내성 글리코시드 하이드로레이즈 패밀리 10 자일라나제
CN116042880A (zh) 2014-10-10 2023-05-02 新泽西鲁特格斯州立大学 结核分枝杆菌的聚合酶链反应引物和探针
EP3310929A2 (de) * 2015-06-19 2018-04-25 Cambridge Enterprise Limited Diagnose und behandlung einer infektionskrankheit
WO2018026141A1 (ko) * 2016-08-04 2018-02-08 주식회사 옵티팜 퀀타매트릭스 어세이 플랫폼 기반 결핵 및 비결핵 항산균의 검출 및 동정과 결핵균의 리팜핀 내성여부를 동시 확인할 수 있는 진단법 및 그 키트
RU2659958C2 (ru) * 2016-10-17 2018-07-04 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ФПИ" Минздрава России) Способ оценки лекарственной чувствительности Mycobacnerium tuberculosis на основе результатов определения иммунологических показателей крови у больного туберкулезом легких человека
WO2020096858A1 (en) * 2018-11-09 2020-05-14 Longhorn Vaccines And Diagnostics, Llc Rapid pcr methodology

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775361A (en) * 1986-04-10 1988-10-04 The General Hospital Corporation Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
ATE163680T1 (de) * 1986-11-24 1998-03-15 Gen Probe Inc Nukleinsäuresonden zum nachweis und/oder zur quantifizierung von nicht-viralen organismen
WO1989006555A1 (en) * 1988-01-21 1989-07-27 Massachusetts Institute Of Technology Transport of molecules across tissue using electroporation
US5749847A (en) * 1988-01-21 1998-05-12 Massachusetts Institute Of Technology Delivery of nucleotides into organisms by electroporation
US5713845A (en) * 1991-10-29 1998-02-03 Thermolase Corporation Laser assisted drug delivery
US5423803A (en) * 1991-10-29 1995-06-13 Thermotrex Corporation Skin surface peeling process using laser
US5246436A (en) * 1991-12-18 1993-09-21 Alcon Surgical, Inc. Midinfrared laser tissue ablater
US5165418B1 (en) * 1992-03-02 1999-12-14 Nikola I Tankovich Blood sampling device and method using a laser
EP0639229B2 (de) 1992-04-30 2009-11-25 Institut Pasteur Schnellnachweis der antibiotikaresistenz in mycobacterium tuberculosis
US5851763A (en) 1992-09-17 1998-12-22 Institut Pasteur Rapid detection of antibiotic resistance in mycobacterium tuberculosis
US5633131A (en) * 1992-04-30 1997-05-27 Institut Pasteur Rapid detection of isoniazid resistance in mycobacterium tuberculosis probes for selecting nucleic acid encoding isoniazid resistance, and methods and kits
US5464386A (en) * 1992-08-17 1995-11-07 Genetronics, Inc. Transdermal drug delivery by electroincorporation of vesicles
US5462520A (en) * 1992-08-17 1995-10-31 Genetronics, Inc. Transsurface drug delivery by electrofusion of microbubbles to the tissue surface
US5643252A (en) * 1992-10-28 1997-07-01 Venisect, Inc. Laser perforator
US5462743A (en) * 1992-10-30 1995-10-31 Medipro Sciences Limited Substance transfer system for topical application
US5458140A (en) * 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5556612A (en) * 1994-03-15 1996-09-17 The General Hospital Corporation Methods for phototherapeutic treatment of proliferative skin diseases
US5505726A (en) * 1994-03-21 1996-04-09 Dusa Pharmaceuticals, Inc. Article of manufacture for the photodynamic therapy of dermal lesion
US5643723A (en) 1994-05-26 1997-07-01 Roche Molecular Systems, Inc. Detection of a genetic locus encoding resistance to rifampin in mycobacterial cultures and in clinical specimens
BR9507960B8 (pt) 1994-06-09 2014-09-30 Fujirebio Europ N V Processos e kits para deteção de resistência à rifampicina e/ou rifabutina de espécies de mycobacterium.
US5554153A (en) * 1994-08-29 1996-09-10 Cell Robotics, Inc. Laser skin perforator

Also Published As

Publication number Publication date
AU2789695A (en) 1996-01-04
US7252936B2 (en) 2007-08-07
WO1995033851A2 (en) 1995-12-14
BR9507960B8 (pt) 2014-09-30
EP0771360A1 (de) 1997-05-07
JP4558105B2 (ja) 2010-10-06
DK0771360T3 (da) 2004-07-12
AU703947B2 (en) 1999-04-01
ATE261496T1 (de) 2004-03-15
BR9507960B1 (pt) 2010-08-10
PT771360E (pt) 2004-07-30
US6329138B1 (en) 2001-12-11
CA2192364C (en) 2009-01-20
EP0771360B1 (de) 2004-03-10
RU2204608C2 (ru) 2003-05-20
WO1995033851A3 (en) 1996-02-08
JPH10500857A (ja) 1998-01-27
CZ361296A3 (en) 1997-07-16
ES2217280T3 (es) 2004-11-01
US20030152982A1 (en) 2003-08-14
DE69532675T2 (de) 2005-02-24
US20090068651A1 (en) 2009-03-12
CA2192364A1 (en) 1995-12-14
CZ298020B6 (cs) 2007-05-23
US6632607B1 (en) 2003-10-14
BR9507960A (pt) 1997-09-02

Similar Documents

Publication Publication Date Title
DE69532675D1 (de) Verfahren zum nachweis des antibiotikaresistenzspektrums von mykobakterium spezies
HK1037687A1 (en) Simultaneous detection, identification and differentiation of mycobacterium species using a hybridization assay
EP0228075A3 (de) Eukaryotisches genomisches DNA Dot-Blot-Hybridisationsverfahren
CA2217325A1 (en) Nucleic acid detection and amplification by chemical linkage of oligonucleotides
DE69740039D1 (de) Verfahren zur typisierung und zum nachweis von hbv
PL278176A1 (en) Method of detecting sequences of nucleotides and sets for carrying out diagnostic tests
WO1999037806A3 (en) Modified nucleic acid probes and uses thereof
SE8604436L (sv) Hybridiseringsforfarande for detektion av polynukleotidsekvens
CA2155387A1 (en) Species-Specific Detection of Mycobacterium Kansasii
CA2075037A1 (en) Methods and reagents for hla drbeta dna typing
DE59611460D1 (de) Extraktion, amplifikation und sequentielle hybridisierung von pilzzellen-dna sowie verfahren zum nachweisen von pilzzellen in klinischem material
EP2302075A3 (de) Verfahren für HLA Typisierung
CA2075052A1 (en) Hla dqbeta dna typing
ATE184055T1 (de) Verfahren zum sensitiven nachweis von reverser transcriptase
DK0689609T3 (da) Fremgangsmåde til typisering af HLA-B under anvendelse af specifikke primere og probesæt
EP0453290A3 (en) Nucleic acid probes for the detection of giardia lamblia and methods of detection
WO1998000565A3 (en) NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING $i(MYCOPLASMA PNEUMONIAE)
WO2001075173A3 (en) β 2 ADRENERGIC POLYMORPHISM DETECTION
CA2211165A1 (en) Methods for sensitive detection of reverse transcriptase

Legal Events

Date Code Title Description
8364 No opposition during term of opposition