DE69529495D1 - Gasbetätigtes element zum austragen von genmaterial - Google Patents

Gasbetätigtes element zum austragen von genmaterial

Info

Publication number
DE69529495D1
DE69529495D1 DE69529495T DE69529495T DE69529495D1 DE 69529495 D1 DE69529495 D1 DE 69529495D1 DE 69529495 T DE69529495 T DE 69529495T DE 69529495 T DE69529495 T DE 69529495T DE 69529495 D1 DE69529495 D1 DE 69529495D1
Authority
DE
Germany
Prior art keywords
particles
gas
actuated element
general material
gas actuated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69529495T
Other languages
English (en)
Other versions
DE69529495T2 (de
Inventor
E Mccabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Powderject Vaccines Inc
Original Assignee
Powderject Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Powderject Vaccines Inc filed Critical Powderject Vaccines Inc
Publication of DE69529495D1 publication Critical patent/DE69529495D1/de
Application granted granted Critical
Publication of DE69529495T2 publication Critical patent/DE69529495T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • A61M2005/005—Magazines with multiple ampoules directly inserted into an injection or infusion device, e.g. revolver-like magazines containing ampoules with or without needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Saccharide Compounds (AREA)
  • Other Surface Treatments For Metallic Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Air Bags (AREA)
DE69529495T 1994-01-21 1995-01-20 Gasbetätigtes element zum austragen von genmaterial Expired - Lifetime DE69529495T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18481294A 1994-01-21 1994-01-21
PCT/US1995/000780 WO1995019799A1 (en) 1994-01-21 1995-01-20 Gas driven gene delivery instrument

Publications (2)

Publication Number Publication Date
DE69529495D1 true DE69529495D1 (de) 2003-03-06
DE69529495T2 DE69529495T2 (de) 2003-06-12

Family

ID=22678443

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69529495T Expired - Lifetime DE69529495T2 (de) 1994-01-21 1995-01-20 Gasbetätigtes element zum austragen von genmaterial
DE69534348T Expired - Lifetime DE69534348T2 (de) 1994-01-21 1995-01-20 Gasbetätigtes Element zum Austragen von Genmaterial

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69534348T Expired - Lifetime DE69534348T2 (de) 1994-01-21 1995-01-20 Gasbetätigtes Element zum Austragen von Genmaterial

Country Status (16)

Country Link
US (2) US5584807A (de)
EP (3) EP1550713A3 (de)
JP (1) JP3221683B2 (de)
CN (1) CN1112943C (de)
AT (2) ATE300609T1 (de)
AU (1) AU674815B2 (de)
BR (1) BR9505691A (de)
CA (2) CA2158733C (de)
DE (2) DE69529495T2 (de)
DK (2) DK1293559T3 (de)
ES (2) ES2247248T3 (de)
HK (1) HK1013804A1 (de)
NZ (1) NZ279995A (de)
PT (1) PT690732E (de)
RU (1) RU2134295C1 (de)
WO (1) WO1995019799A1 (de)

Families Citing this family (196)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW404844B (en) 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
AU674815B2 (en) * 1994-01-21 1997-01-09 Powderject Vaccines, Inc. Gas driven gene delivery instrument
US5899880A (en) * 1994-04-08 1999-05-04 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
GB9416663D0 (en) 1994-08-17 1994-10-12 Oxford Bioscience Limited Particle delivery
EP0788386B1 (de) * 1994-10-24 1999-01-13 PowderJect Research Limited Nadellose spritze
GB9426379D0 (en) 1994-12-23 1995-03-01 Oxford Biosciences Ltd Particle delivery
GB9502879D0 (en) * 1995-02-14 1995-04-05 Oxford Biosciences Ltd Particle delivery
US7223739B1 (en) 1995-06-07 2007-05-29 Powderject Vaccines, Inc. Adjuvanted genetic vaccines
US6013050A (en) * 1995-10-20 2000-01-11 Powderject Research Limited Particle delivery
US5922685A (en) * 1996-06-05 1999-07-13 Powderject Vaccines, Inc. IL-12 gene therapy of tumors
DE69724428T3 (de) * 1996-06-07 2009-07-23 Poniard Pharmaceuticals, Inc., Seattle Humanisierte antikörper die an das gleiche antigen wie antikörper nr-lu-13 binden und deren verwendung in "pretargeting" verfahren
US6053889A (en) * 1996-06-14 2000-04-25 Powderject Vaccines, Inc. Sample delivery module for particle acceleration apparatus
US6893664B1 (en) 1996-06-17 2005-05-17 Powderject Research Limited Particle delivery techniques
CA2266860C (en) * 1996-09-25 2009-06-23 Powderjet Vaccines, Inc. Gas-driven particle delivery device
DE19648625A1 (de) 1996-11-13 1998-05-14 Soft Gene Gmbh Mikroprojektil für das Einbringen von Substanzen in Zellen durch ballistischen Transfer
US5733600A (en) * 1996-11-13 1998-03-31 Powderject Vaccines, Inc. Method and apparatus for preparing sample cartridges for a particle acceleration device
DE19648656B4 (de) * 1996-11-14 2005-08-11 Hiper Ceramics Gmbh Vorrichtung zum Beschleunigen von Partikeln auf Zellen zum ballistischen Transfer
US6200959B1 (en) * 1996-12-04 2001-03-13 Powerject Vaccines Inc. Genetic induction of anti-viral immune response and genetic vaccine for filovirus
US6433154B1 (en) * 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
US5947928A (en) * 1997-06-19 1999-09-07 Mile Creek Capital, Llc Drug delivery system
US7378506B2 (en) * 1997-07-21 2008-05-27 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US6570062B1 (en) 1997-07-21 2003-05-27 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US6639050B1 (en) 1997-07-21 2003-10-28 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US6548642B1 (en) 1997-07-21 2003-04-15 Ohio University Synthetic genes for plant gums
US6355415B1 (en) 1997-09-29 2002-03-12 Ohio University Compositions and methods for the use of ribozymes to determine gene function
US5994624A (en) * 1997-10-20 1999-11-30 Cotton Incorporated In planta method for the production of transgenic plants
ATE316796T1 (de) * 1997-11-20 2006-02-15 Us Army Medical Res And Materi Dna impfstoffe gegen zecken-flavivieren
US6475994B2 (en) * 1998-01-07 2002-11-05 Donald A. Tomalia Method and articles for transfection of genetic material
US20020147143A1 (en) 1998-03-18 2002-10-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US6706948B1 (en) 1998-03-19 2004-03-16 The United States Of America As Represented By The Secretary Of Agriculture Sugarcane UBI9 gene promoter and methods of use thereof
US6686513B1 (en) 1998-03-19 2004-02-03 The United States Of America As Represented By The Secretary Of Agriculture Sugarcane ubi9 gene promoter sequence and methods of use thereof
CA2328397A1 (en) 1998-05-12 1999-11-18 Temple University - Of The Commonwealth System Of Higher Education Human antithrombin iiis and methods related thereto
JP2002517300A (ja) * 1998-06-10 2002-06-18 ジョージア テック リサーチ コーポレイション 微小針デバイスおよび製造方法ならびにそれらの使用
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US20030235557A1 (en) 1998-09-30 2003-12-25 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
IL142680A0 (en) * 1998-10-19 2002-03-10 Powderject Vaccines Inc Minimal promoters and uses thereof
US6881723B1 (en) 1998-11-05 2005-04-19 Powderject Vaccines, Inc. Nucleic acid constructs
US6232113B1 (en) 1998-12-08 2001-05-15 Tien-Li Lee Particle bombardment device
WO2000047227A2 (en) 1999-02-09 2000-08-17 Powderject Vaccines, Inc. Mycobacterium tuberculosis, immunization
EP1180150A2 (de) * 1999-04-21 2002-02-20 Powderject Vaccines, Inc. Nukleinksäure immunizierung
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6398808B1 (en) * 1999-06-15 2002-06-04 Scimed Life Systems, Inc. Localized delivery of genetic information from biostable materials
US7074210B2 (en) * 1999-10-11 2006-07-11 Felton International, Inc. Universal protector cap with auto-disable features for needle-free injectors
WO2001026717A1 (en) 1999-10-11 2001-04-19 Needleless Ventures, Inc. Universal anti-infectious protector for needleless injectors
US7135282B1 (en) 1999-10-14 2006-11-14 The Dow Chemical Company Viral particles with exogenous internal epitopes
SI1227840T1 (sl) * 1999-11-03 2008-02-29 Powderject Vaccines Inc Genetske vakcine z adjuvansom
ATE374622T1 (de) * 1999-11-03 2007-10-15 Powderject Vaccines Inc Genetische impstoffe mit adjuvans
US20040234539A1 (en) * 1999-11-03 2004-11-25 Powderject Research Limited Nucleic acid vaccine compositions having a mammalian cd80/cd86 gene promoter driving antigen expression
AU1358501A (en) * 1999-11-03 2001-05-14 Powderject Vaccines, Inc. Nucleic acid vaccine compositions having a mammalian cd80/cd86 gene promoter driving antigen expression
US7196066B1 (en) 1999-11-03 2007-03-27 Powderject Vaccines, Inc. DNA-vaccines based on constructs derived from the genomes of human and animal pathogens
US20040109874A1 (en) * 1999-11-10 2004-06-10 Powderject Vaccines, Inc. Induction of mucosal immunity by vaccination via the skin route
US7029457B2 (en) * 1999-11-23 2006-04-18 Felton International, Inc. Jet injector with hand piece
US7887506B1 (en) 1999-11-23 2011-02-15 Pulse Needlefree Systems, Inc. Safety mechanism to prevent accidental patient injection and methods of same
US6770054B1 (en) 1999-11-23 2004-08-03 Felton International, Inc. Injector assembly with driving means and locking means
CN1079430C (zh) * 1999-12-11 2002-02-20 周芳 一种高压气体基因枪
FR2802820B1 (fr) * 1999-12-27 2002-10-18 Poudres & Explosifs Ste Nale Seringue sans aiguille fonctionnant par effet tube a choc, avec maintien prealable du principe actif sur le cote
CA2400842C (en) 2000-02-23 2013-01-15 Smithkline Beecham Biologicals S.A. Novel compounds
GB0006263D0 (en) * 2000-03-15 2000-05-03 Powderject Res Ltd Apparatus and method for adjusting the characteristics of a needleless syringe
GB0008494D0 (en) 2000-04-07 2000-05-24 Secr Defence Microprojectile delivery system
US6716190B1 (en) 2000-04-19 2004-04-06 Scimed Life Systems, Inc. Device and methods for the delivery and injection of therapeutic and diagnostic agents to a target site within a body
CN1247314C (zh) 2000-05-16 2006-03-29 明尼苏达大学评议会 电喷射方法和设备
WO2002000174A2 (en) 2000-06-28 2002-01-03 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US6878861B2 (en) * 2000-07-21 2005-04-12 Washington State University Research Foundation Acyl coenzyme A thioesterases
CA2324045A1 (fr) * 2000-10-20 2002-04-20 Universite De Sherbrooke Seringue sans aiguille pour l'injection sous-cutanee de poudres medicamenteuses
GB0025710D0 (en) * 2000-10-20 2000-12-06 Medical Res Council Biolistic device
US7060442B2 (en) * 2000-10-30 2006-06-13 Regents Of The University Of Michigan Modulators on Nod2 signaling
WO2002043774A2 (en) * 2000-11-02 2002-06-06 Powderject Vaccines, Inc. Compositions and therapeutical use of polynucleotides encoding tcrs
JP2005505231A (ja) * 2000-11-03 2005-02-24 リージェンツ オブ ザ ユニバーシティ オブ ミシガン 表面トランスフェクションおよび発現法
US6897067B2 (en) * 2000-11-03 2005-05-24 Regents Of The University Of Michigan Surface transfection and expression procedure
US6902933B2 (en) * 2000-11-03 2005-06-07 Regents Of The University Of Michigan Surface transfection and expression procedure
US7226764B1 (en) 2000-11-08 2007-06-05 The Board Of Trustees Operating Michigan State University Compositions and methods for the synthesis and subsequent modification of uridine-5′-diphosphosulfoquinovose (UDP-SQ)
US6638246B1 (en) 2000-11-28 2003-10-28 Scimed Life Systems, Inc. Medical device for delivery of a biologically active material to a lumen
US7255865B2 (en) * 2000-12-05 2007-08-14 Allergan, Inc. Methods of administering botulinum toxin
WO2002064193A2 (en) 2000-12-14 2002-08-22 Georgia Tech Research Corporation Microneedle devices and production thereof
GB0100756D0 (en) * 2001-01-11 2001-02-21 Powderject Res Ltd Needleless syringe
CA2340998C (en) 2001-03-21 2012-01-03 Saskatchewan Wheat Pool Selective modification of plant fatty acids
US7169597B2 (en) * 2001-04-13 2007-01-30 Michigan State University Compositions and methods for the production of betaine lipids
US7241935B2 (en) * 2001-04-13 2007-07-10 The Board Of Trustees Operating Michigan State University Compositions and methods for the production of betaine lipids
EP1988097A1 (de) 2001-05-09 2008-11-05 Corixa Corporation Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Prostatakrebs
US7247338B2 (en) 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
US20030033637A1 (en) * 2001-06-05 2003-02-13 Croptech Corporation Gene expression and production of TGF-beta proteins including bioactive mullerian inhibiting substance from plants
US8061006B2 (en) 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
WO2003020936A1 (en) * 2001-08-31 2003-03-13 The Dow Chemical Company Nucleic acid compositions conferring altered metabolic characteristics
AU2002327675A1 (en) * 2001-09-19 2003-04-01 Biovalve Technologies, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
PL207168B1 (pl) 2001-09-20 2010-11-30 Glaxo Group Ltd Sekwencja nukleotydowa, wektor, białko, środek farmaceutyczny, urządzenie do podawania śródskórnego, zastosowanie sekwencji nukleotydowej i sposób wytwarzania nukleotydu
CA2499838C (en) * 2001-09-21 2012-12-18 Biovalve Technologies, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
EP1469903A2 (de) * 2001-09-28 2004-10-27 BioValve Technologies, Inc. Mikronadel mit membran
CA2500452A1 (en) * 2001-09-28 2003-04-03 Biovalve Technologies, Inc. Switchable microneedle arrays and systems and methods relating to same
US20040048822A1 (en) * 2001-11-01 2004-03-11 Juan Harrison Nucleic acid immunization
JP2003164289A (ja) * 2001-11-30 2003-06-10 Seikagaku Kogyo Co Ltd 骨組織導入用遺伝子
WO2003053220A2 (en) 2001-12-17 2003-07-03 Corixa Corporation Compositions and methods for the therapy and diagnosis of inflammatory bowel disease
ATE357219T1 (de) * 2002-01-25 2007-04-15 Glaxo Group Ltd Darreichungsformen für dns
US7255986B2 (en) * 2002-01-31 2007-08-14 The Board Of Trustees Operating Michigan State University Compositions for the diagnosis and treatment of epizootic catarrhal enteritis in ferrets
US20030163111A1 (en) * 2002-02-26 2003-08-28 Daellenbach Keith K. End effector for needle-free injection system
NZ534881A (en) 2002-03-19 2006-09-29 Plant Res Internat B Mammalian GnTIII expression in plants
KR101196023B1 (ko) 2002-03-19 2012-10-30 스티칭 디엔스트 랜드보위쿤디그 온데조에크 식물에서 글리칸 프로세싱의 최적화
CA2380671A1 (fr) * 2002-04-05 2003-10-05 Stephane Dufresne Seringue sans aiguille pour l'injection sous-cutanee de gouttelettes medicamenteuses
US7078037B2 (en) * 2002-04-19 2006-07-18 The Arizona Board Of Regents On Behalf Of The University Of Arizona Peptides and DNA encoding the peptides useful for immunizations against Coccidioides spp. infections
AU2003247582A1 (en) * 2002-06-20 2004-01-06 Board Of Trustees Operating Michigan State University Plastid division and related genes and proteins, and methods of use
EP1517605A2 (de) 2002-06-28 2005-03-30 University of Guelph Gene aus luzerne (medicago sativa), die während der ernte induzierbar werden und methoden für deren verwendung
US7329798B2 (en) * 2002-06-28 2008-02-12 University Of Guelph Harvest-inducible regulatory elements and methods of using same
BR0314751A (pt) * 2002-09-27 2005-07-26 Powderject Res Ltd Partìculas adequadas para suprimento a partir de um dispositivo de suprimento, receptáculo de dosagem para um dispositivo de suprimento, dispositivo de suprimento mediado por partìcula, processo para a preparação de partìculas adequadas para suprimento a partir de um dispositivo de suprimento, e, métodos de imunização por ácido nucleico e de terapia genética
CA2500270A1 (en) * 2002-09-27 2004-04-08 Powderject Research Limited Nucleic acid constructs for gene expression
US6920521B2 (en) * 2002-10-10 2005-07-19 International Business Machines Corporation Method and system of managing virtualized physical memory in a data processing system
US6863731B2 (en) * 2002-10-18 2005-03-08 Controls Corporation Of America System for deposition of inert barrier coating to increase corrosion resistance
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
HUE026376T2 (en) 2003-01-06 2016-05-30 Corixa Corp Certain aminoalkyl glucosamide phosphate compounds and their use
US7262027B2 (en) * 2003-03-14 2007-08-28 Medical College Of Ohio Polypeptide and DNA immunization against Coccidioides spp. infections
US20040241750A1 (en) * 2003-03-24 2004-12-02 David Nordman Novel methods for determining the negative control value for multi-analyte assays
US20060252120A1 (en) * 2003-05-09 2006-11-09 Kieliszewski Marcia J Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US7655833B2 (en) * 2003-05-29 2010-02-02 Brookhaven Science Associates, Llc ADS genes for reducing saturated fatty acid levels in seed oils
GB0321615D0 (en) 2003-09-15 2003-10-15 Glaxo Group Ltd Improvements in vaccination
PL1685251T3 (pl) * 2003-10-10 2014-07-31 Powderject Vaccines Inc Konstrukty kwasu nukleinowego
US8147426B2 (en) * 2003-12-31 2012-04-03 Nipro Diagnostics, Inc. Integrated diagnostic test system
CA2553257A1 (en) * 2004-01-14 2005-08-04 Ohio University Methods of producing peptides/proteins in plants and peptides/proteins produced thereby
US7432057B2 (en) * 2004-01-30 2008-10-07 Michigan State University Genetic test for PSE-susceptible turkeys
AU2004201456B2 (en) * 2004-04-08 2005-11-17 Ronald Allan Greenberg Apparatus and method for transdermal delivery of fluids including oxygen
US8623812B2 (en) * 2004-04-19 2014-01-07 Ohio University Cross-linkable glycoproteins and methods of making the same
US7217428B2 (en) * 2004-05-28 2007-05-15 Technology Innovations Llc Drug delivery apparatus utilizing cantilever
EP1781784A2 (de) 2004-08-02 2007-05-09 BASF Plant Science GmbH Verfahren zur isolierung von transkriptionsterminationssequenzen
EP2305294B1 (de) 2004-09-22 2015-04-01 GlaxoSmithKline Biologicals SA Immunogene Zusammensetzung zur Verwendung zur Impfung gegen Staphylokokken
GB0507997D0 (en) * 2005-02-01 2005-05-25 Powderject Vaccines Inc Nucleic acid constructs
WO2006086782A2 (en) * 2005-02-11 2006-08-17 The Regents Of The University Of California Pneumatic capillary gun for ballistic delivery of microscopic particles into tissue
CN101137752B (zh) 2005-03-08 2013-04-03 巴斯福植物科学有限公司 增强表达的内含子序列
CA2608717A1 (en) * 2005-05-18 2006-11-23 The Board Of Trustees Operating Michigan State University Resistance to soybean aphid in early maturing soybean germplasm
WO2007008708A2 (en) * 2005-07-08 2007-01-18 Ohio University Methods of predicting hyp-glycosylation sites for proteins expressed and secreted in plant cells, and related methods and products
US8998881B2 (en) * 2005-08-10 2015-04-07 Alza Corporation Method for delivering drugs to tissue under microjet propulsion
US8562620B2 (en) * 2008-04-21 2013-10-22 Dfine, Inc. Bone treatment systems
CA2636424A1 (en) 2006-01-09 2007-10-25 The Regents Of The University Of California Immunostimulatory combinations of tnfrsf, tlr, nlr, rhr, purinergic receptor, and cytokine receptor agonists for vaccines and tumor immunotherapy
US20080313769A9 (en) 2006-01-12 2008-12-18 Athenix Corporation EPSP synthase domains conferring glyphosate resistance
US20070164133A1 (en) * 2006-01-18 2007-07-19 Hao-Jan Lin Low pressure gas accelerated gene gun
CA2637883C (en) 2006-01-31 2015-07-07 Regents Of The University Of Minnesota Electrospray coating of objects
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
EP1988941A2 (de) 2006-01-31 2008-11-12 Nanocopoeia, Inc. Oberflächenbeschichtung mit nanoteilchen
US20070190635A1 (en) * 2006-02-10 2007-08-16 Hai-Lung Huang Percussion mechanism for a gene gun
NZ571115A (en) 2006-03-02 2011-11-25 Athenix Corp Method and compositions for improved enzyme activity in transgenic plant
US8075920B2 (en) 2006-05-11 2011-12-13 Regenics A/S Administration of cells and cellular extracts for rejuvenation
US7977535B2 (en) 2006-07-12 2011-07-12 Board Of Trustees Of Michigan State University DNA encoding ring zinc-finger protein and the use of the DNA in vectors and bacteria and in plants
WO2008094316A2 (en) * 2006-09-22 2008-08-07 Stowers Institute Of Medical Research Novel branchiostoma derived fluorescent proteins
US20090061492A1 (en) * 2006-11-15 2009-03-05 The Board Of Trustees For Michigan State University System Method for producing biodiesel
US9040816B2 (en) 2006-12-08 2015-05-26 Nanocopoeia, Inc. Methods and apparatus for forming photovoltaic cells using electrospray
EP2520582A1 (de) 2007-02-12 2012-11-07 The United States of America, as Represented by The Secretary of the Army, on behalf of the U.S. Army Research Institute of Infectious Diseases DNA-Impfstoffe auf Basis von Puumala-Virus M-Segmenten mit voller Länge
GB0708758D0 (en) 2007-05-04 2007-06-13 Powderject Res Ltd Particle cassettes and process thereof
DE102007026752A1 (de) * 2007-06-09 2008-12-11 Ivonne Silvester Vorrichtung zur Aufbewahrung und Applikation von Wirkstoffen
WO2009049351A1 (en) 2007-10-15 2009-04-23 The University Of Queensland Construct system and uses therefor
EP2612868B1 (de) 2007-11-01 2018-08-15 Astellas Pharma Inc. Immunsuppressive Polypeptide und Nucleinsäuren
AU2009244462B2 (en) 2008-05-06 2013-04-11 Cook Medical Technologies Llc Apparatus and methods for delivering therapeutic agents
US9133475B2 (en) 2008-11-26 2015-09-15 Board Of Trustees Of Michigan State University Aphid resistant soybean plants
US8362318B2 (en) 2008-12-18 2013-01-29 Board Of Trustees Of Michigan State University Enzyme directed oil biosynthesis in microalgae
CA2747390C (en) 2008-12-23 2016-10-04 Wilson-Cook Medical Inc. Apparatus and methods for containing and delivering therapeutic agents
CN101768213B (zh) 2008-12-30 2012-05-30 中国科学院遗传与发育生物学研究所 一种与植物分蘖数目相关的蛋白及其编码基因与应用
CN101817879A (zh) 2009-02-26 2010-09-01 中国科学院遗传与发育生物学研究所 金属硫蛋白及其编码基因与应用
US8118777B2 (en) * 2009-05-29 2012-02-21 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
US9101744B2 (en) 2009-05-29 2015-08-11 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
TWI400103B (zh) * 2009-12-03 2013-07-01 Leader Machine Co Ltd Drug delivery device
WO2011082253A2 (en) 2009-12-30 2011-07-07 Board Of Trustees Of Michigan State University A method to produce acetyldiacylglycerols (ac-tags) by expression ofan acetyltransferase gene isolated from euonymus alatus (burning bush)
WO2011082194A2 (en) * 2009-12-30 2011-07-07 E.I. Dupont De Nemours And Company Divider for use with biolistic bombardment device
US9795658B2 (en) 2010-04-20 2017-10-24 Admedus Vaccines Pty Ltd Expression system for modulating an immune response
WO2011138687A2 (en) 2010-05-06 2011-11-10 Regenics As Use of cellular extracts for skin rejuvenation
US9227021B2 (en) 2010-06-29 2016-01-05 Genesis Biosystems, Inc. Microneedle roller (MNR) infusion system
WO2012050907A2 (en) 2010-09-28 2012-04-19 The Regents Of The University Of California Gaba agonists in the treatment of disorders associated with metabolic syndrome and gaba combinations in treatment or prophylaxis of type i diabetes
US20120135526A1 (en) * 2010-11-23 2012-05-31 Kenneth Greenberg Low-pressure biolistic barrels
GB201021881D0 (en) * 2010-12-23 2011-02-02 Profibrix Bv Powder delivery device
WO2012105931A2 (en) 2011-01-31 2012-08-09 The United States Of America, As Represented By The Secretary Of The Army, On Behalf Of The United States Army Sin nombre virus full-length m segment-based dna vaccine
DK2670843T3 (en) 2011-02-03 2015-01-05 Government Of The U S A As Represented By The Secretary Dept Of Health And Human Services MULTIVALENT VACCINES FOR RABIES VIRUS AND FILOVIRUS
US8430839B2 (en) * 2011-04-19 2013-04-30 Palo Alto Research Center Incorporated Drug delivery devices and methods with collimated gas stream and drug reservoir
US8388569B2 (en) * 2011-04-19 2013-03-05 Xerox Corporation Delivery devices and methods with collimated gas stream and particle source
US8486002B2 (en) * 2011-04-19 2013-07-16 Palo Alto Research Center Incorporated Drug delivery devices and methods with collimated gas stream and release-activatable tape
AU2012247572B2 (en) * 2011-04-27 2016-03-17 Biom'up Biomedical haemostatic powder dispenser
DE102011100450B8 (de) 2011-04-27 2013-10-17 Jörg Gerlach Apparat zum Sprühen von Zellen, Herstellung des Apparates, Methode zum Sprühen mit dem Apparat und eine Zellsuspension gesprüht mit dem Apparat
US20150030586A1 (en) 2011-06-21 2015-01-29 Sarah Ellen Warren Compositions and methods for the therapy and diagnosis of cancer
CN102250757B (zh) * 2011-07-20 2013-01-09 宁波新芝生物科技股份有限公司 一种基因枪
CA2875683A1 (en) 2012-06-05 2013-12-12 The Australian National University Vaccination with interleukin-4 antagonists
CA2894448C (en) 2012-12-10 2019-09-17 Regenics As Use of cellular extracts for skin rejuvenation
CA2836403A1 (en) 2013-01-04 2014-07-04 Board Of Trustees Of Michigan State University New sources of aphid resistance in soybean plants
US9783817B2 (en) 2013-03-04 2017-10-10 Arkansas State University Methods of expressing and detecting activity of expansin in plant cells
US9867931B2 (en) 2013-10-02 2018-01-16 Cook Medical Technologies Llc Therapeutic agents for delivery using a catheter and pressure source
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
US10392629B2 (en) 2014-01-17 2019-08-27 Board Of Trustees Of Michigan State University Increased caloric and nutritional content of plant biomass
US9714429B2 (en) 2014-01-28 2017-07-25 Arkansas State University Regulatory sequence of cupin family gene
AR100874A1 (es) 2014-06-16 2016-11-09 Consejo Nac De Investig Científicas Y Técnicas (Conicet) Genes quiméricos y proteínas de resistencia oxidativa, y plantas transgénicas que incluyen los mismos
US10039885B2 (en) 2015-02-09 2018-08-07 Palo Alto Research Center Incorporated System and method for enhancing particle delivery to biological tissue
US10449297B2 (en) * 2015-02-09 2019-10-22 Palo Alto Research Center Incorporated Alignment of elongated particles in a particle delivery device
JP2018511655A (ja) 2015-03-20 2018-04-26 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン ボルデテラ属に対するワクチン接種における使用のための免疫原性組成物
JP2017000667A (ja) * 2015-06-16 2017-01-05 国立大学法人三重大学 無針注射器及びそれを用いた注射対象領域へのｄｎａ導入方法
EP3386593A4 (de) 2015-12-09 2019-07-24 Admedus Vaccines Pty Ltd Immunmodulierende zusammensetzung zur behandlung
US11041170B2 (en) 2016-04-04 2021-06-22 Thomas Jefferson University Multivalent vaccines for rabies virus and coronaviruses
CN105820942B (zh) * 2016-05-24 2017-12-19 中国农业科学院棉花研究所 一种基因枪用活塞样品架
CA3027493C (en) 2016-06-14 2021-04-06 Renovacare Sciences Corp. Modular device for cell spraying
WO2018018082A1 (en) 2016-07-26 2018-02-01 The Australian National University Immunostimulatory compositions and uses therefor
FR3085959B1 (fr) * 2018-09-18 2020-11-20 Centre Nat Rech Scient Dispositif de distribution de microbulles pour une sonoporation cellulaire
WO2020079484A1 (en) 2018-10-19 2020-04-23 Regenics As Use of egg cellular extract for wound healing
WO2021108308A1 (en) * 2019-11-26 2021-06-03 Georgia Tech Research Corporation Systems and devices for delivering cargo material and methods of delivering cargo materials
WO2021195089A1 (en) 2020-03-23 2021-09-30 Sorrento Therapeutics, Inc. Fc-coronavirus antigen fusion proteins, and nucleic acids, vectors, compositions and methods of use thereof
WO2022269570A1 (en) * 2021-06-24 2022-12-29 Avectas Limited Spray nozzle

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2632444A (en) * 1951-06-14 1953-03-24 Kas John Leo Pellet injector
US2850013A (en) * 1956-03-20 1958-09-02 Cordis Nat Animal pellet injector gun
US3744493A (en) * 1972-01-10 1973-07-10 Syntex Corp Implanter having an improved cartridge ejector
GB8311345D0 (en) * 1983-04-26 1983-06-02 Dobson Park Ind Oral administration of capsules to animals
US4945050A (en) * 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5015580A (en) * 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
IL84459A (en) * 1986-12-05 1993-07-08 Agracetus Apparatus and method for the injection of carrier particles carrying genetic material into living cells
US5120657A (en) * 1986-12-05 1992-06-09 Agracetus, Inc. Apparatus for genetic transformation
US4941880A (en) * 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
CA1310870C (en) * 1987-11-16 1992-12-01 Medhi-Tek International Limited Apparatus for hypodermic injection of liquids
US5179022A (en) * 1988-02-29 1993-01-12 E. I. Du Pont De Nemours & Co. Biolistic apparatus for delivering substances into cells and tissues in a non-lethal manner
DK479189D0 (da) * 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator
CN1052695A (zh) * 1989-12-22 1991-07-03 中国科学院生物物理研究所 一种转移基因的方法及其转移基因的粒子枪
US5066587A (en) * 1990-01-26 1991-11-19 The Upjohn Company Gas driven microprojectile accelerator and method of use
US5204253A (en) * 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5149655A (en) * 1990-06-21 1992-09-22 Agracetus, Inc. Apparatus for genetic transformation
WO1992004439A1 (en) * 1990-08-30 1992-03-19 Brian John Bellhouse Ballistic apparatus
US5147295A (en) * 1991-01-23 1992-09-15 Ideal Instruments, Inc. Retractable implanter
TW404844B (en) * 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
AU674815B2 (en) * 1994-01-21 1997-01-09 Powderject Vaccines, Inc. Gas driven gene delivery instrument

Also Published As

Publication number Publication date
ES2247248T3 (es) 2006-03-01
CA2158733A1 (en) 1995-07-27
JPH08509131A (ja) 1996-10-01
JP3221683B2 (ja) 2001-10-22
AU674815B2 (en) 1997-01-09
CA2501743C (en) 2008-11-18
DE69534348T2 (de) 2006-05-24
HK1013804A1 (en) 1999-09-10
CA2158733C (en) 2007-01-16
DK1293559T3 (da) 2005-11-28
CN1124460A (zh) 1996-06-12
PT690732E (pt) 2003-06-30
ATE231733T1 (de) 2003-02-15
NZ279995A (en) 1998-04-27
DE69534348D1 (de) 2005-09-01
BR9505691A (pt) 1996-01-16
RU2134295C1 (ru) 1999-08-10
EP0690732A1 (de) 1996-01-10
CA2501743A1 (en) 1995-07-27
DE69529495T2 (de) 2003-06-12
WO1995019799A1 (en) 1995-07-27
US5584807A (en) 1996-12-17
EP1550713A2 (de) 2005-07-06
ES2192573T3 (es) 2003-10-16
US5865796A (en) 1999-02-02
EP0690732B1 (de) 2003-01-29
EP1550713A3 (de) 2007-09-12
EP1293559B1 (de) 2005-07-27
ATE300609T1 (de) 2005-08-15
DK0690732T3 (da) 2003-05-19
CN1112943C (zh) 2003-07-02
EP0690732A4 (de) 1996-06-12
EP1293559A1 (de) 2003-03-19
AU1729595A (en) 1995-08-08

Similar Documents

Publication Publication Date Title
DE69529495T2 (de) Gasbetätigtes element zum austragen von genmaterial
EP0356455B1 (de) Pulverspritzvorrichtung
EP0848654A4 (de)
ATE43078T1 (de) Verfahren zur gleichmaessigen verteilung voneinander getrennter teilchen auf einem bewegten poroesen gewebe.
DE69320277D1 (de) Vorrichtung zum gleichzeitigen Verteilen von verschiedenen Partikelförmigen Materialien und Absaugen dieser Partikel und Verfahren zur Erzeugung von gemusterten Artikeln mittels dieser Vorrichtung
US5360511A (en) Apparatus and method for spray drying solids-laden high temperature gases
WO2003028868A8 (en) Apparatus and method for fabricating high density microarrays and applications thereof
CA2257141A1 (en) Sample delivery module for particle acceleration apparatus
EP1321538A3 (de) Gasverteiler für Dampfphasenbeschichtungsverfahren und -Anlage
CA1285751C (en) Method of intermittent powder coating
DK0655597T3 (da) Fremgangsmåde og apparat til tørring af væskebåret fast materiale
ATE248749T1 (de) Vorrichtung und verfahren um ein produkt einer kontrollierten atmosphäre auszusetzen
ATE144232T1 (de) Vorrichtung und verfahren zur glasbeschichtung
DE69617574D1 (de) Vorrichtung zum Aussortieren von schweren und leichten Materialteilchen
US4901921A (en) Particle injection device for thermal spraying
JPH09108518A (ja) 集塵機におけるプリコート剤の供給装置
EP0393918A3 (de) Behandlung von Oberflächen
ATE17089T1 (de) Verfahren und vorrichtung zur abtrennung von teilchen aus einem gasstrom.
RU2002128473A (ru) Способ обработки поверхности изделий, способ подготовки поверхности для последующего нанесения покрытия и устройство для их осуществления
EP0770423A3 (de) Vorrichtung und Verfahren zum Granulieren von Pulver
DE69700673T2 (de) Vorrichtung zum stimulierten Ausstossen von Material unter Druck unter Verwendung einer verschliessbaren Düse
GB2073410A (en) Recovering particulate materials from mixtures containing them
JPH06285398A (ja) 塗装装置の塗料噴射機
WO1992002349A2 (en) The removal of material from surfaces

Legal Events

Date Code Title Description
8364 No opposition during term of opposition