DE69526353D1 - Immunologische aktivität der rhamnolipide - Google Patents

Immunologische aktivität der rhamnolipide

Info

Publication number
DE69526353D1
DE69526353D1 DE69526353T DE69526353T DE69526353D1 DE 69526353 D1 DE69526353 D1 DE 69526353D1 DE 69526353 T DE69526353 T DE 69526353T DE 69526353 T DE69526353 T DE 69526353T DE 69526353 D1 DE69526353 D1 DE 69526353D1
Authority
DE
Germany
Prior art keywords
rhamnolipid
immunological activity
mono
saturated
polyunsaturated hydrocarbyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69526353T
Other languages
English (en)
Inventor
Goran Piljac
Visnja Piljac
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69526353D1 publication Critical patent/DE69526353D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Rheumatology (AREA)
DE69526353T 1994-07-20 1995-07-20 Immunologische aktivität der rhamnolipide Expired - Lifetime DE69526353D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/277,975 US5466675A (en) 1992-02-04 1994-07-20 Immunological activity of rhamnolipids
PCT/US1995/008787 WO1996002233A1 (en) 1994-07-20 1995-07-20 Immunological activity of rhamnolipids

Publications (1)

Publication Number Publication Date
DE69526353D1 true DE69526353D1 (de) 2002-05-16

Family

ID=23063162

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526353T Expired - Lifetime DE69526353D1 (de) 1994-07-20 1995-07-20 Immunologische aktivität der rhamnolipide

Country Status (8)

Country Link
US (2) US5466675A (de)
EP (1) EP0771191B1 (de)
JP (2) JP4316672B2 (de)
AT (1) ATE215827T1 (de)
AU (1) AU3126695A (de)
CA (1) CA2195419C (de)
DE (1) DE69526353D1 (de)
WO (1) WO1996002233A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1056462T3 (da) * 1998-02-24 2007-12-03 Paradigm Biomedical Inc Anvendelse af rhamnolipider som kosmetiske midler
US7262171B1 (en) * 1998-02-24 2007-08-28 Paradigm Biomedical, Inc. Use of rhamnolipids in wound healing, treating burn shock, atherosclerosis, organ transplants, depression, schizophrenia and cosmetics
EP1889623A3 (de) * 1998-02-24 2009-04-08 Paradigm Biomedical Inc. Verwendung von Rhamnolipiden für die Wundheilung, für die Behandlung von Verbrennungen, Arteriosklerose, Organtransplantationen, Depressionen und Schizophrenie sowie für Kosmetikartikel
WO2001010447A1 (en) * 1999-08-05 2001-02-15 Tamara Stipcevic Use of rhamnolipids in wound healing, treatment and prevention of gum disease and periodontal regeneration
US6921390B2 (en) * 2001-07-23 2005-07-26 Boston Scientific Scimed, Inc. Long-term indwelling medical devices containing slow-releasing antimicrobial agents and having a surfactant surface
US7262178B2 (en) * 2003-03-24 2007-08-28 Polytechnic University Treatment of sepsis and septic shock
US20050164955A1 (en) * 2003-11-06 2005-07-28 Gross Richard A. Antifungal properties of various forms of sophorolipids
EP2046930A4 (de) * 2006-07-27 2012-06-27 Aurora Advance Beauty Labs Auf rhamnolipid basierende formulierungen
US8592381B2 (en) 2008-12-18 2013-11-26 Rhamnopharma Inc. Method for treating rhinitis and sinusitis by rhamnolipids
IT1393093B1 (it) 2009-02-18 2012-04-11 Bluegreen Biotech S R L Miscela glicolipidica da oscillatoria planktothrix con attivita' immunomodulante ed antiinfiammatoria
BR112013014236B1 (pt) 2010-12-09 2021-03-30 Y&B Mother's Choice Ltd Composição cosmética ou de limpeza e produto de consumo
EP2648809B1 (de) 2010-12-09 2019-04-03 Y&B Mother's Choice Ltd. Natürliche formulierungen
US10434058B2 (en) 2010-12-09 2019-10-08 Y&B Mother's Choice Ltd. Natural formulations
EP2723348B1 (de) 2011-06-21 2019-08-14 Anton Leighton Verfahren zur behandlung von adipositas
US9861702B2 (en) 2012-10-22 2018-01-09 Wisconsin Alumni Research Foundation Lipid-conjugated rhamnose for immune system recruitment and oncotherapy
DE102012221519A1 (de) * 2012-11-26 2014-05-28 Evonik Industries Ag Verfahren zur Isolierung von Rhamnolipiden
IL229836A0 (en) 2013-12-08 2014-03-31 Y & B Mother S Choice Ltd Formulations to reduce or suppress irritation to eye tissue
CN107735495A (zh) * 2015-05-05 2018-02-23 罗格斯技术有限责任公司 以高产量和滴度产生鼠李糖脂的半连续工艺
ES2898721T3 (es) 2016-12-22 2022-03-08 Oreal Uso de ramnolípidos para el tratamiento cosmético de la piel reactiva
EP3338762A1 (de) 2016-12-22 2018-06-27 L'oreal Verwendung von rhamnolipid zur behandlung von hautrötung
WO2018195613A1 (en) 2017-04-28 2018-11-01 L'oreal Deodorant composition
KR102112570B1 (ko) * 2019-01-28 2020-05-19 한국해양과학기술원 신규 람노리피드 화합물 및 이의 용도
WO2024011093A1 (en) * 2022-07-08 2024-01-11 Woolsey Pharmaceuticals, Inc. Treating amyotrophic lateral sclerosis having onset 24 months prior to treatment
WO2024011094A1 (en) * 2022-07-08 2024-01-11 Woolsey Pharmaceuticals, Inc. Regimen for treating amyotrophic lateral sclerosis having onset 24 months prior to treatment
CN116585352A (zh) * 2023-04-21 2023-08-15 江南大学 一种鼠李糖脂/富勒烯复合物在结肠炎药物及改善肠道微生物群中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135099A3 (de) * 1983-08-09 1987-05-13 Petrotec Systems AG Verfahren zur Herstellung von Tensiden
DE3405664A1 (de) * 1984-02-17 1985-09-05 Wintershall Ag, 3100 Celle Verfahren zur biotechnischen herstellung von rhamnolipiden und rhamnolipide mit nur einem ss-hydroxidecancarbonsaeurerest im molekuel
JPS63182029A (ja) * 1987-01-22 1988-07-27 Agency Of Ind Science & Technol リポソ−ム
US4933281A (en) * 1987-03-17 1990-06-12 The University Of Iowa Research Foundation Method for producing rhamnose
JPS63253025A (ja) * 1987-04-09 1988-10-20 Yamanouchi Pharmaceut Co Ltd ホスホリパ−ゼａ↓２阻害剤
EP0288965A2 (de) * 1987-04-29 1988-11-02 Hoechst Aktiengesellschaft Peptide mit Phospholipase A2- hemmender Wirkung
JPH0273093A (ja) * 1988-09-09 1990-03-13 Haruo Ogura ３−デオキシ−ｄ−グリセロ−ｄ−ガラクト−２−ノヌロピラノソン酸誘導体
IT1235162B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisosfingolipidi
FR2645741B1 (fr) * 1989-03-20 1995-06-23 Dior Christian Parfums Procede pour fixer un produit sur la membrane d'un keratinocyte au moyen d'une liaison ligand-recepteur, procede de preparation d'un tel produit, produit obtenu, composition cosmetique ou pharmaceutique le contenant et son procede de preparation
BE1005704A4 (nl) * 1992-02-04 1993-12-21 Piljac Goran & Piljac Visnja Farmaceutisch preparaat op basis van rhamnolipide.
BE1005825A4 (nl) * 1992-05-22 1994-02-08 Piljac Goran Oppervlakteactieve samenstelling op basis van rhamnolopide.

Also Published As

Publication number Publication date
CA2195419C (en) 2008-01-22
CA2195419A1 (en) 1996-02-01
EP0771191A1 (de) 1997-05-07
US5466675A (en) 1995-11-14
EP0771191B1 (de) 2002-04-10
JPH10502925A (ja) 1998-03-17
ATE215827T1 (de) 2002-04-15
JP4316672B2 (ja) 2009-08-19
WO1996002233A1 (en) 1996-02-01
JP2007308514A (ja) 2007-11-29
AU3126695A (en) 1996-02-16
US5514661A (en) 1996-05-07
EP0771191A4 (de) 1998-10-07

Similar Documents

Publication Publication Date Title
DE69526353D1 (de) Immunologische aktivität der rhamnolipide
ATE229524T1 (de) Distamycin a analoga als antitumor- oder antivirale wirkstoffe
FR2430410A1 (fr) Phenethanolamines et compositions pharmaceutiques en contenant
ATE1814T1 (de) 9-hydroxyalkylpurine, verfahren zu ihrer herstellung und 9-hydroxyalkylpurine als aktive mittel enthaltende therapeutische zusammensetzung.
NO843836L (no) Terapeutisk aktive sulfamatderivater
ATE72448T1 (de) 2-alkynyladenosine als aktive bestandteile enthaltende antihypertensive mittel.
RU96117038A (ru) Композиция для обработки полости рта
FI810389L (fi) Foerfarande foer framstaellning av substituerade imidazolderivat
GB2210556B (en) The use of 15-keto-16-halo-prostaglandins in cathartic compositions
GB2075341B (en) Pharmaceutical compositions
MD1688G2 (ro) Benzotiofen, benzofuran şi indoltiazepinone, oxazepinone şi diazepinone, compoziţie farmaceutică, metodă de inhibare a aderării leucocitelor la celulele endoteliale pentru tratamentul proceselor inflamatorii şi metodă de tratament al mamiferelor infectate cu HIV infecţie .
FR2418214A1 (fr) Compose de formule 1-(2',6',6'-trimethylcyclohexyl)-hexane-3-ol utilise notamment comme fixateur pour compositions de parfums
SE8801514L (sv) Farmaceutisk komposition
SE9601677D0 (sv) New use
FR2430408A1 (fr) Phenethanolamines optiquement actives et leur utilisation therapeutique
TNSN90021A1 (fr) Procede de preparation de tetrahydroimidazo (1,4) benzodiazepin -2- thiones antivirales
FR2426679A1 (de)
FR2455587A1 (fr) Derives de benzimidazole, leur preparation et utilisation dans le traitement des affections cardiovasculaires et compositions les contenant
FR2445329A1 (fr) Derives du 11-bromo-14-oxo-15-hydroxy-imino-e-homo-eburnane, leur preparation et leur utilisation comme medicament
BR9611472A (pt) Compostos de di-terc-butilfenol contendo enxofre úteis como agentes antiinflamatórios
FR2420344A1 (fr) Nouveaux oxime-ethers, leur preparation et leur application therapeutique.
DK0632717T3 (da) Middel til anvendelse som et anti-irritationsmiddel
FI875729A0 (fi) Cytostatiska platinafoereningar.
EP0253378A3 (de) 13Beta-Alkyl-derivate von S541-Antibiotika zur Bekämpfung von Parasiten an Nutztieren und Pflanzen
FR2418792A1 (fr) Derives de 3-azabicyclo(3.1.0)hexane, procede pour leur preparation, compositions biologiquement actives les contenant et procede herbicide les utilisant

Legal Events

Date Code Title Description
8332 No legal effect for de